PIRD: Pan immune repertoire database Article Swipe
Wei Zhang
,
Longlong Wang
,
Ke Liu
,
Xiaofeng Wei
,
Kai Yang
,
Wensi Du
,
Shiyu Wang
,
Nannan Guo
,
Chuanchuan Ma
,
Lihua Luo
,
Jinghua Wu
,
Liya Lin
,
Fan Yang
,
Fei Gao
,
Xie Wang
,
Tao Li
,
Ruifang Zhang
,
Nitin K. Saksena
,
Huanming Yang
,
Jian Wang
,
Lin Fang
,
Yong Hou
,
Xun Xu
,
Xiao Liu
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1101/399493
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1101/399493
Motivation T and B cell receptors (TCRs and BCRs) play a pivotal role in the adaptive immune system by recognizing an enormous variety of external and internal antigens. Understanding these receptors is critical for exploring the process of immunoreaction and exploiting potential applications in immunotherapy and antibody drug design. Although a large number of samples have had their TCR and BCR repertoires sequenced using high-throughput sequencing in recent years, very few databases have been constructed to store these kinds of data. To resolve this issue, we developed a database. Results We developed a database, the Pan Immune Repertoire Database (PIRD), located in China National GeneBank (CNGBdb), to collect and store annotated TCR and BCR sequencing data, including from Homo sapiens and other species. In addition to data storage, PIRD also provides functions of data visualisation and interactive online analysis. Additionally, a manually curated database of TCRs and BCRs targeting known antigens (TBAdb) was also deposited in PIRD. Availability and Implementation PIRD can be freely accessed at https://db.cngb.org/pird .
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Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/399493
- OA Status
- green
- Cited By
- 5
- References
- 58
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2888151585
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W2888151585Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/399493Digital Object Identifier
- Title
-
PIRD: Pan immune repertoire databaseWork title
- Type
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preprintOpenAlex work type
- Language
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enPrimary language
- Publication year
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2018Year of publication
- Publication date
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2018-08-25Full publication date if available
- Authors
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Wei Zhang, Longlong Wang, Ke Liu, Xiaofeng Wei, Kai Yang, Wensi Du, Shiyu Wang, Nannan Guo, Chuanchuan Ma, Lihua Luo, Jinghua Wu, Liya Lin, Fan Yang, Fei Gao, Xie Wang, Tao Li, Ruifang Zhang, Nitin K. Saksena, Huanming Yang, Jian Wang, Lin Fang, Yong Hou, Xun Xu, Xiao LiuList of authors in order
- Landing page
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https://doi.org/10.1101/399493Publisher landing page
- Open access
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://curis.ku.dk/portal/da/publications/pird(9b657681-e81d-40cd-a175-f8466b243895).htmlDirect OA link when available
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Repertoire, T-cell receptor, Database, Computational biology, Antigen, Biology, Computer science, breakpoint cluster region, Immune system, T cell, Gene, Immunology, Genetics, Acoustics, PhysicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
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2025: 1, 2024: 2, 2020: 1, 2019: 1Per-year citation counts (last 5 years)
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58Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| countries_distinct_count | 2 |
| institutions_distinct_count | 24 |
| corresponding_institution_ids | https://openalex.org/I100135526, https://openalex.org/I4210149137 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7699999809265137 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.51759977 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |