Platelet Pathophysiology: Unexpected New Research Directions Article Swipe
Alan D. Michelson
,
Andrew L. Frelinger
,
Robin L. Haynes
,
Hannah C. Kinney
,
Thomas Gremmel
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1055/s-0044-1787663
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1055/s-0044-1787663
We are very honored that our 2016 review of platelet physiology[1] is one of the top three most downloaded papers in Seminars and Thrombosis and Haemostasis from 2014 to 2023. But why study platelet physiology? Because these remarkable little cells play key roles in many important pathophysiological processes, including thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis, and tumor growth and metastasis.[2] In addition to primary disorders of platelet number and function, platelets have a critical role in many other very common diseases, including coronary artery disease, stroke, peripheral vascular disease, and diabetes mellitus.[2] There remain many incompletely understood aspects of platelet physiology and its relationship to diseases, a few examples of which are the role of platelets in innate and adaptive immunity,[3] [4] the genetic basis of thrombocytopenia,[5] the role of platelet activation in coronavirus disease 2019,[6] the role of platelet activation in liver disease,[7] and novel targets for antiplatelet therapy.[8] [9] [10] But science in general, and the study of platelet physiology in particular, can sometimes lead researchers in an unexpected new direction, as will be discussed in this commentary focused on the relationship between platelet function and sudden infant death syndrome (SIDS).
Related Topics
Concepts
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1055/s-0044-1787663
- OA Status
- green
- Cited By
- 4
- References
- 41
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4399761587
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4399761587Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1055/s-0044-1787663Digital Object Identifier
- Title
-
Platelet Pathophysiology: Unexpected New Research DirectionsWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-06-18Full publication date if available
- Authors
-
Alan D. Michelson, Andrew L. Frelinger, Robin L. Haynes, Hannah C. Kinney, Thomas GremmelList of authors in order
- Landing page
-
https://doi.org/10.1055/s-0044-1787663Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.ncbi.nlm.nih.gov/pmc/articles/11471377Direct OA link when available
- Concepts
-
Platelet, Medicine, Disease, Platelet activation, Thrombosis, Pathophysiology, Coronary artery disease, Angiogenesis, Immunology, Bioinformatics, Pathology, Internal medicine, BiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
4Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 2, 2024: 2Per-year citation counts (last 5 years)
- References (count)
-
41Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4399761587 |
|---|---|
| doi | https://doi.org/10.1055/s-0044-1787663 |
| ids.doi | https://doi.org/10.1055/s-0044-1787663 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38889800 |
| ids.openalex | https://openalex.org/W4399761587 |
| fwci | 2.29590714 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000378 |
| mesh[1].descriptor_ui | D001792 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | metabolism |
| mesh[1].descriptor_name | Blood Platelets |
| mesh[2].qualifier_ui | Q000502 |
| mesh[2].descriptor_ui | D001792 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | physiology |
| mesh[2].descriptor_name | Blood Platelets |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D006801 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Humans |
| mesh[4].qualifier_ui | Q000378 |
| mesh[4].descriptor_ui | D001792 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | metabolism |
| mesh[4].descriptor_name | Blood Platelets |
| mesh[5].qualifier_ui | Q000502 |
| mesh[5].descriptor_ui | D001792 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | physiology |
| mesh[5].descriptor_name | Blood Platelets |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D006801 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Humans |
| mesh[7].qualifier_ui | Q000378 |
| mesh[7].descriptor_ui | D001792 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | metabolism |
| mesh[7].descriptor_name | Blood Platelets |
| mesh[8].qualifier_ui | Q000502 |
| mesh[8].descriptor_ui | D001792 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | physiology |
| mesh[8].descriptor_name | Blood Platelets |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D006801 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Humans |
| mesh[10].qualifier_ui | Q000378 |
| mesh[10].descriptor_ui | D001792 |
| mesh[10].is_major_topic | True |
| mesh[10].qualifier_name | metabolism |
| mesh[10].descriptor_name | Blood Platelets |
| mesh[11].qualifier_ui | Q000502 |
| mesh[11].descriptor_ui | D001792 |
| mesh[11].is_major_topic | True |
| mesh[11].qualifier_name | physiology |
| mesh[11].descriptor_name | Blood Platelets |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D006801 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Humans |
| mesh[13].qualifier_ui | Q000378 |
| mesh[13].descriptor_ui | D001792 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | metabolism |
| mesh[13].descriptor_name | Blood Platelets |
| mesh[14].qualifier_ui | Q000502 |
| mesh[14].descriptor_ui | D001792 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | physiology |
| mesh[14].descriptor_name | Blood Platelets |
| type | review |
| title | Platelet Pathophysiology: Unexpected New Research Directions |
| biblio.issue | 08 |
| biblio.volume | 50 |
| biblio.last_page | 1190 |
| biblio.first_page | 1187 |
| topics[0].id | https://openalex.org/T11456 |
| topics[0].field.id | https://openalex.org/fields/28 |
| topics[0].field.display_name | Neuroscience |
| topics[0].score | 0.9932000041007996 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2807 |
| topics[0].subfield.display_name | Endocrine and Autonomic Systems |
| topics[0].display_name | Neuroscience of respiration and sleep |
| topics[1].id | https://openalex.org/T11171 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9884999990463257 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1311 |
| topics[1].subfield.display_name | Genetics |
| topics[1].display_name | Diabetes and associated disorders |
| topics[2].id | https://openalex.org/T10560 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9854000210762024 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2712 |
| topics[2].subfield.display_name | Endocrinology, Diabetes and Metabolism |
| topics[2].display_name | Diabetes Management and Research |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C89560881 |
| concepts[0].level | 2 |
| concepts[0].score | 0.7677435874938965 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q101026 |
| concepts[0].display_name | Platelet |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.6873793601989746 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C2779134260 |
| concepts[2].level | 2 |
| concepts[2].score | 0.5956776738166809 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q12136 |
| concepts[2].display_name | Disease |
| concepts[3].id | https://openalex.org/C3018697912 |
| concepts[3].level | 3 |
| concepts[3].score | 0.587792694568634 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q179217 |
| concepts[3].display_name | Platelet activation |
| concepts[4].id | https://openalex.org/C2780868729 |
| concepts[4].level | 2 |
| concepts[4].score | 0.544996976852417 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q261327 |
| concepts[4].display_name | Thrombosis |
| concepts[5].id | https://openalex.org/C10162356 |
| concepts[5].level | 2 |
| concepts[5].score | 0.5105324983596802 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q1135939 |
| concepts[5].display_name | Pathophysiology |
| concepts[6].id | https://openalex.org/C2778213512 |
| concepts[6].level | 2 |
| concepts[6].score | 0.4692307114601135 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q844935 |
| concepts[6].display_name | Coronary artery disease |
| concepts[7].id | https://openalex.org/C2780394083 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4625586271286011 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q539568 |
| concepts[7].display_name | Angiogenesis |
| concepts[8].id | https://openalex.org/C203014093 |
| concepts[8].level | 1 |
| concepts[8].score | 0.457701712846756 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[8].display_name | Immunology |
| concepts[9].id | https://openalex.org/C60644358 |
| concepts[9].level | 1 |
| concepts[9].score | 0.34488028287887573 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q128570 |
| concepts[9].display_name | Bioinformatics |
| concepts[10].id | https://openalex.org/C142724271 |
| concepts[10].level | 1 |
| concepts[10].score | 0.25278592109680176 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[10].display_name | Pathology |
| concepts[11].id | https://openalex.org/C126322002 |
| concepts[11].level | 1 |
| concepts[11].score | 0.2404915988445282 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[11].display_name | Internal medicine |
| concepts[12].id | https://openalex.org/C86803240 |
| concepts[12].level | 0 |
| concepts[12].score | 0.17231446504592896 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[12].display_name | Biology |
| keywords[0].id | https://openalex.org/keywords/platelet |
| keywords[0].score | 0.7677435874938965 |
| keywords[0].display_name | Platelet |
| keywords[1].id | https://openalex.org/keywords/medicine |
| keywords[1].score | 0.6873793601989746 |
| keywords[1].display_name | Medicine |
| keywords[2].id | https://openalex.org/keywords/disease |
| keywords[2].score | 0.5956776738166809 |
| keywords[2].display_name | Disease |
| keywords[3].id | https://openalex.org/keywords/platelet-activation |
| keywords[3].score | 0.587792694568634 |
| keywords[3].display_name | Platelet activation |
| keywords[4].id | https://openalex.org/keywords/thrombosis |
| keywords[4].score | 0.544996976852417 |
| keywords[4].display_name | Thrombosis |
| keywords[5].id | https://openalex.org/keywords/pathophysiology |
| keywords[5].score | 0.5105324983596802 |
| keywords[5].display_name | Pathophysiology |
| keywords[6].id | https://openalex.org/keywords/coronary-artery-disease |
| keywords[6].score | 0.4692307114601135 |
| keywords[6].display_name | Coronary artery disease |
| keywords[7].id | https://openalex.org/keywords/angiogenesis |
| keywords[7].score | 0.4625586271286011 |
| keywords[7].display_name | Angiogenesis |
| keywords[8].id | https://openalex.org/keywords/immunology |
| keywords[8].score | 0.457701712846756 |
| keywords[8].display_name | Immunology |
| keywords[9].id | https://openalex.org/keywords/bioinformatics |
| keywords[9].score | 0.34488028287887573 |
| keywords[9].display_name | Bioinformatics |
| keywords[10].id | https://openalex.org/keywords/pathology |
| keywords[10].score | 0.25278592109680176 |
| keywords[10].display_name | Pathology |
| keywords[11].id | https://openalex.org/keywords/internal-medicine |
| keywords[11].score | 0.2404915988445282 |
| keywords[11].display_name | Internal medicine |
| keywords[12].id | https://openalex.org/keywords/biology |
| keywords[12].score | 0.17231446504592896 |
| keywords[12].display_name | Biology |
| language | en |
| locations[0].id | doi:10.1055/s-0044-1787663 |
| locations[0].is_oa | False |
| locations[0].source.id | https://openalex.org/S96726197 |
| locations[0].source.issn | 0094-6176, 1098-9064 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 0094-6176 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Seminars in Thrombosis and Hemostasis |
| locations[0].source.host_organization | https://openalex.org/P4310320000 |
| locations[0].source.host_organization_name | Thieme Medical Publishers (Germany) |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320000 |
| locations[0].license | |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Seminars in Thrombosis and Hemostasis |
| locations[0].landing_page_url | https://doi.org/10.1055/s-0044-1787663 |
| locations[1].id | pmid:38889800 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Seminars in thrombosis and hemostasis |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38889800 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11471377 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Semin Thromb Hemost |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11471377 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5049630475 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-1746-4819 |
| authorships[0].author.display_name | Alan D. Michelson |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I1288882113, https://openalex.org/I136199984, https://openalex.org/I4210117453 |
| authorships[0].affiliations[0].raw_affiliation_string | Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts |
| authorships[0].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[0].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Boston Children's Hospital |
| authorships[0].institutions[1].id | https://openalex.org/I4210117453 |
| authorships[0].institutions[1].ror | https://ror.org/02jzgtq86 |
| authorships[0].institutions[1].type | facility |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210117453 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | Dana-Farber Cancer Institute |
| authorships[0].institutions[2].id | https://openalex.org/I136199984 |
| authorships[0].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[0].institutions[2].type | education |
| authorships[0].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[0].institutions[2].country_code | US |
| authorships[0].institutions[2].display_name | Harvard University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Alan D. Michelson |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts |
| authorships[1].author.id | https://openalex.org/A5067192657 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-6871-7441 |
| authorships[1].author.display_name | Andrew L. Frelinger |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I1288882113, https://openalex.org/I136199984, https://openalex.org/I4210117453 |
| authorships[1].affiliations[0].raw_affiliation_string | Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts |
| authorships[1].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[1].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Boston Children's Hospital |
| authorships[1].institutions[1].id | https://openalex.org/I4210117453 |
| authorships[1].institutions[1].ror | https://ror.org/02jzgtq86 |
| authorships[1].institutions[1].type | facility |
| authorships[1].institutions[1].lineage | https://openalex.org/I4210117453 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | Dana-Farber Cancer Institute |
| authorships[1].institutions[2].id | https://openalex.org/I136199984 |
| authorships[1].institutions[2].ror | https://ror.org/03vek6s52 |
| authorships[1].institutions[2].type | education |
| authorships[1].institutions[2].lineage | https://openalex.org/I136199984 |
| authorships[1].institutions[2].country_code | US |
| authorships[1].institutions[2].display_name | Harvard University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Andrew L. Frelinger III |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Division of Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts |
| authorships[2].author.id | https://openalex.org/A5058695201 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-4909-9585 |
| authorships[2].author.display_name | Robin L. Haynes |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I1288882113, https://openalex.org/I136199984 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts |
| authorships[2].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[2].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Boston Children's Hospital |
| authorships[2].institutions[1].id | https://openalex.org/I136199984 |
| authorships[2].institutions[1].ror | https://ror.org/03vek6s52 |
| authorships[2].institutions[1].type | education |
| authorships[2].institutions[1].lineage | https://openalex.org/I136199984 |
| authorships[2].institutions[1].country_code | US |
| authorships[2].institutions[1].display_name | Harvard University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Robin L. Haynes |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts |
| authorships[3].author.id | https://openalex.org/A5069304796 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-5199-279X |
| authorships[3].author.display_name | Hannah C. Kinney |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I1288882113, https://openalex.org/I136199984 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts |
| authorships[3].institutions[0].id | https://openalex.org/I1288882113 |
| authorships[3].institutions[0].ror | https://ror.org/00dvg7y05 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I1288882113 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Boston Children's Hospital |
| authorships[3].institutions[1].id | https://openalex.org/I136199984 |
| authorships[3].institutions[1].ror | https://ror.org/03vek6s52 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I136199984 |
| authorships[3].institutions[1].country_code | US |
| authorships[3].institutions[1].display_name | Harvard University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Hannah C. Kinney |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts |
| authorships[4].author.id | https://openalex.org/A5076070541 |
| authorships[4].author.orcid | https://orcid.org/0000-0001-9554-7292 |
| authorships[4].author.display_name | Thomas Gremmel |
| authorships[4].countries | AT |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210129948 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Internal Medicine I, Cardiology and Intensive Care Medicine, Landesklinikum Mistelbach-Gänserndorf, Mistelbach, Austria |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I4210161345 |
| authorships[4].affiliations[1].raw_affiliation_string | Institute of Cardiovascular Pharmacotherapy and Interventional Cardiology, Karl Landsteiner Society, St. Pölten, Austria |
| authorships[4].affiliations[2].institution_ids | https://openalex.org/I4210149039 |
| authorships[4].affiliations[2].raw_affiliation_string | Karl Landsteiner University of Health Sciences, Krems, Austria |
| authorships[4].institutions[0].id | https://openalex.org/I4210161345 |
| authorships[4].institutions[0].ror | https://ror.org/05r0e4p82 |
| authorships[4].institutions[0].type | other |
| authorships[4].institutions[0].lineage | https://openalex.org/I4210161345 |
| authorships[4].institutions[0].country_code | AT |
| authorships[4].institutions[0].display_name | Karl Landsteiner Society |
| authorships[4].institutions[1].id | https://openalex.org/I4210149039 |
| authorships[4].institutions[1].ror | https://ror.org/04t79ze18 |
| authorships[4].institutions[1].type | education |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210149039 |
| authorships[4].institutions[1].country_code | AT |
| authorships[4].institutions[1].display_name | Karl Landsteiner University of Health Sciences |
| authorships[4].institutions[2].id | https://openalex.org/I4210129948 |
| authorships[4].institutions[2].ror | https://ror.org/03n0q0765 |
| authorships[4].institutions[2].type | healthcare |
| authorships[4].institutions[2].lineage | https://openalex.org/I4210129948 |
| authorships[4].institutions[2].country_code | AT |
| authorships[4].institutions[2].display_name | Landesklinikum Korneuburg |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Thomas Gremmel |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Internal Medicine I, Cardiology and Intensive Care Medicine, Landesklinikum Mistelbach-Gänserndorf, Mistelbach, Austria, Institute of Cardiovascular Pharmacotherapy and Interventional Cardiology, Karl Landsteiner Society, St. Pölten, Austria, Karl Landsteiner University of Health Sciences, Krems, Austria |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11471377 |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Platelet Pathophysiology: Unexpected New Research Directions |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11456 |
| primary_topic.field.id | https://openalex.org/fields/28 |
| primary_topic.field.display_name | Neuroscience |
| primary_topic.score | 0.9932000041007996 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2807 |
| primary_topic.subfield.display_name | Endocrine and Autonomic Systems |
| primary_topic.display_name | Neuroscience of respiration and sleep |
| related_works | https://openalex.org/W2075734225, https://openalex.org/W2042474810, https://openalex.org/W2561802298, https://openalex.org/W3152246802, https://openalex.org/W2127463799, https://openalex.org/W73242545, https://openalex.org/W638153814, https://openalex.org/W4206699628, https://openalex.org/W4210967366, https://openalex.org/W2123707479 |
| cited_by_count | 4 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 2 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 2 |
| locations_count | 3 |
| best_oa_location.id | pmh:oai:pubmedcentral.nih.gov:11471377 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2764455111 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | PubMed Central |
| best_oa_location.source.host_organization | https://openalex.org/I1299303238 |
| best_oa_location.source.host_organization_name | National Institutes of Health |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I1299303238 |
| best_oa_location.license | |
| best_oa_location.pdf_url | |
| best_oa_location.version | submittedVersion |
| best_oa_location.raw_type | Text |
| best_oa_location.license_id | |
| best_oa_location.is_accepted | False |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | Semin Thromb Hemost |
| best_oa_location.landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11471377 |
| primary_location.id | doi:10.1055/s-0044-1787663 |
| primary_location.is_oa | False |
| primary_location.source.id | https://openalex.org/S96726197 |
| primary_location.source.issn | 0094-6176, 1098-9064 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 0094-6176 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Seminars in Thrombosis and Hemostasis |
| primary_location.source.host_organization | https://openalex.org/P4310320000 |
| primary_location.source.host_organization_name | Thieme Medical Publishers (Germany) |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320000 |
| primary_location.license | |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Seminars in Thrombosis and Hemostasis |
| primary_location.landing_page_url | https://doi.org/10.1055/s-0044-1787663 |
| publication_date | 2024-06-18 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W4256314182, https://openalex.org/W2403674414, https://openalex.org/W4206012410, https://openalex.org/W4394728290, https://openalex.org/W4394714701, https://openalex.org/W4376129094, https://openalex.org/W4390265265, https://openalex.org/W2807642223, https://openalex.org/W3001654026, https://openalex.org/W4308991631, https://openalex.org/W2208416917, https://openalex.org/W2973153970, https://openalex.org/W2052554098, https://openalex.org/W87529271, https://openalex.org/W1606835851, https://openalex.org/W2109831177, https://openalex.org/W2104671291, https://openalex.org/W2102488356, https://openalex.org/W2969763909, https://openalex.org/W2097785193, https://openalex.org/W2004862250, https://openalex.org/W1969144895, https://openalex.org/W2062528505, https://openalex.org/W2156303565, https://openalex.org/W2049543100, https://openalex.org/W2015442311, https://openalex.org/W2159920363, https://openalex.org/W4391592209, https://openalex.org/W2724974118, https://openalex.org/W4396934349, https://openalex.org/W2084691835, https://openalex.org/W4391324472, https://openalex.org/W2032998869, https://openalex.org/W3092261881, https://openalex.org/W4385254308, https://openalex.org/W3180897730, https://openalex.org/W3009178140, https://openalex.org/W1967141088, https://openalex.org/W2183920415, https://openalex.org/W4206628154, https://openalex.org/W4225870322 |
| referenced_works_count | 41 |
| abstract_inverted_index.a | 75, 109 |
| abstract_inverted_index.In | 63 |
| abstract_inverted_index.We | 0 |
| abstract_inverted_index.an | 172 |
| abstract_inverted_index.as | 176 |
| abstract_inverted_index.be | 178 |
| abstract_inverted_index.in | 20, 43, 78, 119, 135, 144, 157, 165, 171, 180 |
| abstract_inverted_index.is | 11 |
| abstract_inverted_index.of | 8, 13, 68, 101, 112, 117, 128, 132, 141, 162 |
| abstract_inverted_index.on | 184 |
| abstract_inverted_index.to | 28, 65, 107 |
| abstract_inverted_index.But | 30, 155 |
| abstract_inverted_index.[4] | 124 |
| abstract_inverted_index.[9] | 153 |
| abstract_inverted_index.and | 22, 24, 58, 61, 71, 92, 104, 121, 147, 159, 190 |
| abstract_inverted_index.are | 1, 114 |
| abstract_inverted_index.can | 167 |
| abstract_inverted_index.few | 110 |
| abstract_inverted_index.for | 150 |
| abstract_inverted_index.its | 105 |
| abstract_inverted_index.key | 41 |
| abstract_inverted_index.new | 174 |
| abstract_inverted_index.one | 12 |
| abstract_inverted_index.our | 5 |
| abstract_inverted_index.the | 14, 115, 125, 130, 139, 160, 185 |
| abstract_inverted_index.top | 15 |
| abstract_inverted_index.why | 31 |
| abstract_inverted_index.2014 | 27 |
| abstract_inverted_index.2016 | 6 |
| abstract_inverted_index.[10] | 154 |
| abstract_inverted_index.from | 26 |
| abstract_inverted_index.have | 74 |
| abstract_inverted_index.host | 53 |
| abstract_inverted_index.lead | 169 |
| abstract_inverted_index.many | 44, 79, 97 |
| abstract_inverted_index.most | 17 |
| abstract_inverted_index.play | 40 |
| abstract_inverted_index.role | 77, 116, 131, 140 |
| abstract_inverted_index.that | 4 |
| abstract_inverted_index.this | 181 |
| abstract_inverted_index.very | 2, 81 |
| abstract_inverted_index.will | 177 |
| abstract_inverted_index.2023. | 29 |
| abstract_inverted_index.There | 95 |
| abstract_inverted_index.basis | 127 |
| abstract_inverted_index.cells | 39 |
| abstract_inverted_index.death | 193 |
| abstract_inverted_index.liver | 145 |
| abstract_inverted_index.novel | 148 |
| abstract_inverted_index.other | 80 |
| abstract_inverted_index.roles | 42 |
| abstract_inverted_index.study | 32, 161 |
| abstract_inverted_index.these | 36 |
| abstract_inverted_index.three | 16 |
| abstract_inverted_index.tumor | 59 |
| abstract_inverted_index.which | 113 |
| abstract_inverted_index.wound | 55 |
| abstract_inverted_index.artery | 86 |
| abstract_inverted_index.common | 82 |
| abstract_inverted_index.growth | 60 |
| abstract_inverted_index.infant | 192 |
| abstract_inverted_index.innate | 120 |
| abstract_inverted_index.little | 38 |
| abstract_inverted_index.number | 70 |
| abstract_inverted_index.papers | 19 |
| abstract_inverted_index.remain | 96 |
| abstract_inverted_index.review | 7 |
| abstract_inverted_index.sudden | 191 |
| abstract_inverted_index.(SIDS). | 195 |
| abstract_inverted_index.Because | 35 |
| abstract_inverted_index.aspects | 100 |
| abstract_inverted_index.between | 187 |
| abstract_inverted_index.disease | 137 |
| abstract_inverted_index.focused | 183 |
| abstract_inverted_index.genetic | 126 |
| abstract_inverted_index.honored | 3 |
| abstract_inverted_index.primary | 66 |
| abstract_inverted_index.science | 156 |
| abstract_inverted_index.stroke, | 88 |
| abstract_inverted_index.targets | 149 |
| abstract_inverted_index.2019,[6] | 138 |
| abstract_inverted_index.Seminars | 21 |
| abstract_inverted_index.adaptive | 122 |
| abstract_inverted_index.addition | 64 |
| abstract_inverted_index.coronary | 85 |
| abstract_inverted_index.critical | 76 |
| abstract_inverted_index.defense, | 54 |
| abstract_inverted_index.diabetes | 93 |
| abstract_inverted_index.disease, | 87, 91 |
| abstract_inverted_index.examples | 111 |
| abstract_inverted_index.function | 189 |
| abstract_inverted_index.general, | 158 |
| abstract_inverted_index.healing, | 56 |
| abstract_inverted_index.platelet | 9, 33, 69, 102, 133, 142, 163, 188 |
| abstract_inverted_index.syndrome | 194 |
| abstract_inverted_index.vascular | 90 |
| abstract_inverted_index.discussed | 179 |
| abstract_inverted_index.diseases, | 83, 108 |
| abstract_inverted_index.disorders | 67 |
| abstract_inverted_index.function, | 72 |
| abstract_inverted_index.important | 45 |
| abstract_inverted_index.including | 48, 84 |
| abstract_inverted_index.platelets | 73, 118 |
| abstract_inverted_index.sometimes | 168 |
| abstract_inverted_index.Thrombosis | 23 |
| abstract_inverted_index.activation | 134, 143 |
| abstract_inverted_index.commentary | 182 |
| abstract_inverted_index.direction, | 175 |
| abstract_inverted_index.downloaded | 18 |
| abstract_inverted_index.peripheral | 89 |
| abstract_inverted_index.physiology | 103, 164 |
| abstract_inverted_index.processes, | 47 |
| abstract_inverted_index.remarkable | 37 |
| abstract_inverted_index.understood | 99 |
| abstract_inverted_index.unexpected | 173 |
| abstract_inverted_index.Haemostasis | 25 |
| abstract_inverted_index.coronavirus | 136 |
| abstract_inverted_index.disease,[7] | 146 |
| abstract_inverted_index.hemorrhage, | 50 |
| abstract_inverted_index.particular, | 166 |
| abstract_inverted_index.physiology? | 34 |
| abstract_inverted_index.researchers | 170 |
| abstract_inverted_index.therapy.[8] | 152 |
| abstract_inverted_index.thrombosis, | 49 |
| abstract_inverted_index.antiplatelet | 151 |
| abstract_inverted_index.immunity,[3] | 123 |
| abstract_inverted_index.incompletely | 98 |
| abstract_inverted_index.mellitus.[2] | 94 |
| abstract_inverted_index.relationship | 106, 186 |
| abstract_inverted_index.angiogenesis, | 57 |
| abstract_inverted_index.antimicrobial | 52 |
| abstract_inverted_index.inflammation, | 51 |
| abstract_inverted_index.physiology[1] | 10 |
| abstract_inverted_index.metastasis.[2] | 62 |
| abstract_inverted_index.pathophysiological | 46 |
| abstract_inverted_index.thrombocytopenia,[5] | 129 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 94 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 5 |
| citation_normalized_percentile.value | 0.80204342 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |