PMSG and HCG hormones effect on the development and growth of ovarian follicles Article Swipe
Masoumeh Majidi Zolbin
,
Sepidah Nematin
,
Faeze Daghigh
,
Fariba Namdar
,
Mahmoodreza Madadian
,
Mahdi Abbasi
,
Seyed Mohammad Hosein Noori Mogahi
,
Nasrin Takzaree
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.22317/jcms.03201811
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.22317/jcms.03201811
Objective Gonadotropins are generally used in animals and humans to stimulate ovulation and increase the number of available oocytes for techniques such as in vitro fertilization. Ovulation-inducing drugs are used to achieve multiple oocytes in one cycle, thereby increasing the chances of pregnancy in patients with infertility. The aim of this study was to evaluate the effect of gonadotropins on stimulation of ovulation and their inductive role on the growth and development of follicles in the ovary. Methods To determine the effect of human chronic gonadotrophin (HCG) and pregnant mare serum gonadotrophin (PMSG) on ovary, this study used 20 rats that were randomly divided to experimental and control groups. Rats were subsequently euthanized 48 h after injection and the ovaries were fixed and stained with H&E. Data were analyzed with Tukey’s multiple comparisons with one-way ANOVA test in GraphPad Prism software. Result Our analysis demonstrated that HCG and PMSG hormones will significantly increase the number of stimulated oocyte in the ovary but it does not have any significant role on the ovary weight and volume (P < 0.05). Conclusion This study’s results confirmed the inductive role of PMSG and HCG hormones on folliculogenesis.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.22317/jcms.03201811
- http://www.jocms.org/index.php/jcms/article/download/340/195/
- OA Status
- gold
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- References
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- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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- DOI
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https://doi.org/10.22317/jcms.03201811Digital Object Identifier
- Title
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PMSG and HCG hormones effect on the development and growth of ovarian folliclesWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2018Year of publication
- Publication date
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2018-03-26Full publication date if available
- Authors
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Masoumeh Majidi Zolbin, Sepidah Nematin, Faeze Daghigh, Fariba Namdar, Mahmoodreza Madadian, Mahdi Abbasi, Seyed Mohammad Hosein Noori Mogahi, Nasrin TakzareeList of authors in order
- Landing page
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https://doi.org/10.22317/jcms.03201811Publisher landing page
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https://www.jocms.org/index.php/jcms/article/download/340/195/Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.jocms.org/index.php/jcms/article/download/340/195/Direct OA link when available
- Concepts
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Hormone, Ovary, Endocrinology, Andrology, Biology, Internal medicine, MedicineTop concepts (fields/topics) attached by OpenAlex
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8Total citation count in OpenAlex
- Citations by year (recent)
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2024: 2, 2023: 1, 2022: 3, 2021: 2Per-year citation counts (last 5 years)
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20Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| primary_location.raw_source_name | Journal of Contemporary Medical Sciences |
| primary_location.landing_page_url | https://doi.org/10.22317/jcms.03201811 |
| publication_date | 2018-03-26 |
| publication_year | 2018 |
| referenced_works | https://openalex.org/W2064320023, https://openalex.org/W2574224286, https://openalex.org/W4300982572, https://openalex.org/W2001731917, https://openalex.org/W4232583658, https://openalex.org/W6666374803, https://openalex.org/W2083030380, https://openalex.org/W2068796004, https://openalex.org/W2408219734, https://openalex.org/W2007932490, https://openalex.org/W2091024514, https://openalex.org/W2114066459, https://openalex.org/W2711117354, https://openalex.org/W2118545571, https://openalex.org/W4234939150, https://openalex.org/W2087209804, https://openalex.org/W4242201858, https://openalex.org/W2131644540, https://openalex.org/W2064525704, https://openalex.org/W2099401496 |
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