Point-of-Care Ultrasound in the Diagnosis of Melioidosis in Laos Article Swipe
YOU?
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· 2020
· Open Access
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· DOI: https://doi.org/10.4269/ajtmh.20-0069
Melioidosis is endemic in many rural areas in Southeast Asia where facilities for culture and identification of Burkholderia pseudomallei are often limited. We performed a prospective observational study in patients presenting with fever to Mahosot Hospital, the primary referral hospital in Laos, to establish whether the detection of abscesses on ultrasound could support a presumptive diagnosis of melioidosis. All patients underwent ultrasound examination to detect abscesses in the liver, spleen, prostate, or, if indicated, subcutaneous tissue. We enrolled 153 patients, including 18 patients with melioidosis. Of these, 11 (61%) had an abscess at one or more sites, including five (28%) with splenic and/or liver abscesses. Absence of abscesses cannot rule out melioidosis, but the positive predictive value of abscesses for melioidosis was high at 93% (88-96%). Therefore, in endemic areas, the presence of abscesses in febrile patients should prompt empiric antibiotic therapy for melioidosis even in the absence of culture confirmation.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.4269/ajtmh.20-0069
- https://www.ajtmh.org/downloadpdf/journals/tpmd/103/2/article-p675.pdf
- OA Status
- hybrid
- Cited By
- 10
- References
- 13
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3029718119
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3029718119Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.4269/ajtmh.20-0069Digital Object Identifier
- Title
-
Point-of-Care Ultrasound in the Diagnosis of Melioidosis in LaosWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-06-02Full publication date if available
- Authors
-
Michaëla A. M. Huson, Kerstin Kling, Somaphone Chankongsin, Khampheng Phongluxa, Valy Keoluangkhot, Paul N. Newton, David A. B. Dance, Tom Heller, Andreas NeumayrList of authors in order
- Landing page
-
https://doi.org/10.4269/ajtmh.20-0069Publisher landing page
- PDF URL
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https://www.ajtmh.org/downloadpdf/journals/tpmd/103/2/article-p675.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://www.ajtmh.org/downloadpdf/journals/tpmd/103/2/article-p675.pdfDirect OA link when available
- Concepts
-
Melioidosis, Burkholderia pseudomallei, Medicine, Liver abscess, Abscess, Internal medicine, Surgery, Pathology, Biology, Genetics, BacteriaTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
10Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2023: 7, 2022: 1, 2020: 1Per-year citation counts (last 5 years)
- References (count)
-
13Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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