Positive Ratio of Polymerase Chain Reaction (PCR) and Validity of Pre-Screening Criteria at an Outpatient Screening Center during the Early Phase of the COVID-19 Epidemic in Japan Article Swipe
Satoshi Ide
,
Kayoko Hayakawa
,
Kei Yamamoto
,
Shinya Tsuzuki
,
Junko Tanuma
,
Kaori Ohara
,
Gen Yamada
,
Ayako Okuhama
,
Kohei Kanda
,
Tetsuya Suzuki
,
Yutaro Akiyama
,
Yusuke Miyazato
,
Keiji Nakamura
,
Hidetoshi Nomoto
,
Takato Nakamoto
,
Mugen Ujiie
,
Sho Saito
,
Shinichiro Morioka
,
Masahiro Ishikane
,
Noriko Kinoshita
,
Satoshi Kutsuna
,
Keiko Tanaka
,
Norio Ohmagari
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.7883/yoken.jjid.2020.813
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.7883/yoken.jjid.2020.813
Despite the increase in COVID-19 cases globally, the number of cases in Japan has been relatively low, and an explosive surge in the prevalence has not occurred. In March 2020, the Ministry of Health, Labour and Welfare (MHLW) in Japan recommended the original criteria for polymerase chain reaction (PCR) testing, although there was a lack of evidence for appropriate targets for COVID-19 testing. This study aimed to evaluate the COVID-19 positive ratio and pre-screening criteria in Tokyo immediately after the insurance-covered SARS-CoV-2 PCR testing became available in Japan. We subjected 277 individuals with mild symptoms in metropolitan Tokyo (positive: 9.0%) from March 9 to 29, 2020, to SARS-CoV-2 PCR testing. The results revealed that 25 (9.0%) of them were PCR-positive. The sensitivity and specificity of the MHLW criteria were 100% and 10.7%, respectively. When the criteria excluded nonspecific symptoms, fatigue, and dyspnea, the sensitivity slightly decreased to 92%, and the specificity increased to 22.2%. The specificity was highest when the fever criterion was ≥37.5°C for ≥4 days, and exposure/travel history, including age and underlying comorbidities, was considered. Our findings suggest that the MHLW criteria, including the symptoms and exposure/travel history, may be useful for COVID-19 pre-screening.
Related Topics
Concepts
Medicine
Coronavirus disease 2019 (COVID-19)
Christian ministry
Polymerase chain reaction
Internal medicine
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Biology
Genetics
Gene
Disease
Philosophy
Theology
Infectious disease (medical specialty)
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.7883/yoken.jjid.2020.813
- https://www.jstage.jst.go.jp/article/yoken/74/5/74_JJID.2020.813/_pdf
- OA Status
- diamond
- Cited By
- 2
- References
- 5
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3135484152
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3135484152Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.7883/yoken.jjid.2020.813Digital Object Identifier
- Title
-
Positive Ratio of Polymerase Chain Reaction (PCR) and Validity of Pre-Screening Criteria at an Outpatient Screening Center during the Early Phase of the COVID-19 Epidemic in JapanWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-02-25Full publication date if available
- Authors
-
Satoshi Ide, Kayoko Hayakawa, Kei Yamamoto, Shinya Tsuzuki, Junko Tanuma, Kaori Ohara, Gen Yamada, Ayako Okuhama, Kohei Kanda, Tetsuya Suzuki, Yutaro Akiyama, Yusuke Miyazato, Keiji Nakamura, Hidetoshi Nomoto, Takato Nakamoto, Mugen Ujiie, Sho Saito, Shinichiro Morioka, Masahiro Ishikane, Noriko Kinoshita, Satoshi Kutsuna, Keiko Tanaka, Norio OhmagariList of authors in order
- Landing page
-
https://doi.org/10.7883/yoken.jjid.2020.813Publisher landing page
- PDF URL
-
https://www.jstage.jst.go.jp/article/yoken/74/5/74_JJID.2020.813/_pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
diamondOpen access status per OpenAlex
- OA URL
-
https://www.jstage.jst.go.jp/article/yoken/74/5/74_JJID.2020.813/_pdfDirect OA link when available
- Concepts
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Medicine, Coronavirus disease 2019 (COVID-19), Christian ministry, Polymerase chain reaction, Internal medicine, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Biology, Genetics, Gene, Disease, Philosophy, Theology, Infectious disease (medical specialty)Top concepts (fields/topics) attached by OpenAlex
- Cited by
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2Total citation count in OpenAlex
- Citations by year (recent)
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2022: 2Per-year citation counts (last 5 years)
- References (count)
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5Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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