Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip Article Swipe
Jiarui Wu
,
Haoyang Yu
,
Xiaowei Dou
,
Bin Yin
,
Hou‐Wen Lin
,
Yuanchao Xue
,
Boqin Qiang
,
Pengcheng Shu
,
Xiaozhong Peng
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1002/advs.202411732
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1002/advs.202411732
The development of the mammalian neocortex is precisely regulated by temporal gene expression, yet the temporal regulatory mechanisms of cortical neurogenesis, particularly how radial glial cells (RGCs) sequentially generate deep to superficial neurons, remain unclear. Here, the hnRNP family member Syncrip (hnRNP Q) is identified as a key modulator of superficial neuronal differentiation in neocortical neurogenesis. Syncrip knockout in RGCs disrupts differentiation and abnormal neuronal localization, ultimately resulting in superficial cortical layer defects as well as learning and memory impairments in mice. Single‐cell RNA sequencing analysis demonstrated that the knockout of Syncrip disrupts the late‐stage neurogenesis, stalling transcriptional progression in RGCs. Mechanistically, Syncrip maintains the transcription of temporal process‐related transcription factors by recruiting stabilization complexes through phase separation, crucially regulating the Notch signaling pathway that determines the fate of RGCs. Furthermore, pathogenic human mutations in Syncrip weaken its phase‐separation capability, failing to form stable complexes normally. Thus, Syncrip acts as a mediator of posttranscriptional regulatory mechanisms, governing the fate progression of RGCs and the advancement of intrinsic temporal programs. This study establishes an intracellular mechanism for posttranscriptional regulation of progressive fate determination in cortical neurogenesis.
Related Topics
Concepts
Neurogenesis
Neocortex
Biology
Cell fate determination
Neural stem cell
Neuroscience
Transcription factor
Cell biology
Conditional gene knockout
Fate mapping
Progenitor cell
Stem cell
Gene
Genetics
Phenotype
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/advs.202411732
- OA Status
- gold
- Cited By
- 1
- References
- 67
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4406117135
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4406117135Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/advs.202411732Digital Object Identifier
- Title
-
Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by SyncripWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-01-07Full publication date if available
- Authors
-
Jiarui Wu, Haoyang Yu, Xiaowei Dou, Bin Yin, Hou‐Wen Lin, Yuanchao Xue, Boqin Qiang, Pengcheng Shu, Xiaozhong PengList of authors in order
- Landing page
-
https://doi.org/10.1002/advs.202411732Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1002/advs.202411732Direct OA link when available
- Concepts
-
Neurogenesis, Neocortex, Biology, Cell fate determination, Neural stem cell, Neuroscience, Transcription factor, Cell biology, Conditional gene knockout, Fate mapping, Progenitor cell, Stem cell, Gene, Genetics, PhenotypeTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1Per-year citation counts (last 5 years)
- References (count)
-
67Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4406117135 |
|---|---|
| doi | https://doi.org/10.1002/advs.202411732 |
| ids.doi | https://doi.org/10.1002/advs.202411732 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/39776340 |
| ids.openalex | https://openalex.org/W4406117135 |
| fwci | 2.68294463 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000818 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Animals |
| mesh[1].qualifier_ui | Q000378 |
| mesh[1].descriptor_ui | D019579 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | metabolism |
| mesh[1].descriptor_name | Neocortex |
| mesh[2].qualifier_ui | Q000166 |
| mesh[2].descriptor_ui | D019579 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | cytology |
| mesh[2].descriptor_name | Neocortex |
| mesh[3].qualifier_ui | |
| mesh[3].descriptor_ui | D051379 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | |
| mesh[3].descriptor_name | Mice |
| mesh[4].qualifier_ui | Q000235 |
| mesh[4].descriptor_ui | D055495 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | genetics |
| mesh[4].descriptor_name | Neurogenesis |
| mesh[5].qualifier_ui | Q000502 |
| mesh[5].descriptor_ui | D055495 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | physiology |
| mesh[5].descriptor_name | Neurogenesis |
| mesh[6].qualifier_ui | Q000378 |
| mesh[6].descriptor_ui | D058953 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | metabolism |
| mesh[6].descriptor_name | Neural Stem Cells |
| mesh[7].qualifier_ui | Q000166 |
| mesh[7].descriptor_ui | D058953 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | cytology |
| mesh[7].descriptor_name | Neural Stem Cells |
| mesh[8].qualifier_ui | Q000378 |
| mesh[8].descriptor_ui | D034441 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | metabolism |
| mesh[8].descriptor_name | Heterogeneous-Nuclear Ribonucleoproteins |
| mesh[9].qualifier_ui | Q000235 |
| mesh[9].descriptor_ui | D034441 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | genetics |
| mesh[9].descriptor_name | Heterogeneous-Nuclear Ribonucleoproteins |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D018345 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Mice, Knockout |
| mesh[11].qualifier_ui | Q000235 |
| mesh[11].descriptor_ui | D002454 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | genetics |
| mesh[11].descriptor_name | Cell Differentiation |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D016601 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | RNA-Binding Proteins |
| mesh[13].qualifier_ui | |
| mesh[13].descriptor_ui | D000818 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | |
| mesh[13].descriptor_name | Animals |
| mesh[14].qualifier_ui | Q000378 |
| mesh[14].descriptor_ui | D019579 |
| mesh[14].is_major_topic | True |
| mesh[14].qualifier_name | metabolism |
| mesh[14].descriptor_name | Neocortex |
| mesh[15].qualifier_ui | Q000254 |
| mesh[15].descriptor_ui | D019579 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | growth & development |
| mesh[15].descriptor_name | Neocortex |
| mesh[16].qualifier_ui | Q000196 |
| mesh[16].descriptor_ui | D019579 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | embryology |
| mesh[16].descriptor_name | Neocortex |
| mesh[17].qualifier_ui | |
| mesh[17].descriptor_ui | D051379 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | |
| mesh[17].descriptor_name | Mice |
| mesh[18].qualifier_ui | Q000235 |
| mesh[18].descriptor_ui | D055495 |
| mesh[18].is_major_topic | True |
| mesh[18].qualifier_name | genetics |
| mesh[18].descriptor_name | Neurogenesis |
| mesh[19].qualifier_ui | Q000502 |
| mesh[19].descriptor_ui | D055495 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | physiology |
| mesh[19].descriptor_name | Neurogenesis |
| mesh[20].qualifier_ui | Q000378 |
| mesh[20].descriptor_ui | D058953 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | metabolism |
| mesh[20].descriptor_name | Neural Stem Cells |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D006801 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Humans |
| mesh[22].qualifier_ui | Q000235 |
| mesh[22].descriptor_ui | D034441 |
| mesh[22].is_major_topic | True |
| mesh[22].qualifier_name | genetics |
| mesh[22].descriptor_name | Heterogeneous-Nuclear Ribonucleoproteins |
| mesh[23].qualifier_ui | Q000378 |
| mesh[23].descriptor_ui | D034441 |
| mesh[23].is_major_topic | True |
| mesh[23].qualifier_name | metabolism |
| mesh[23].descriptor_name | Heterogeneous-Nuclear Ribonucleoproteins |
| mesh[24].qualifier_ui | Q000235 |
| mesh[24].descriptor_ui | D002454 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | genetics |
| mesh[24].descriptor_name | Cell Differentiation |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D018345 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Mice, Knockout |
| mesh[26].qualifier_ui | Q000378 |
| mesh[26].descriptor_ui | D009474 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | metabolism |
| mesh[26].descriptor_name | Neurons |
| mesh[27].qualifier_ui | Q000378 |
| mesh[27].descriptor_ui | D063928 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | metabolism |
| mesh[27].descriptor_name | Ependymoglial Cells |
| mesh[28].qualifier_ui | |
| mesh[28].descriptor_ui | D015398 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | |
| mesh[28].descriptor_name | Signal Transduction |
| mesh[29].qualifier_ui | |
| mesh[29].descriptor_ui | D000818 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | |
| mesh[29].descriptor_name | Animals |
| mesh[30].qualifier_ui | Q000378 |
| mesh[30].descriptor_ui | D019579 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | metabolism |
| mesh[30].descriptor_name | Neocortex |
| mesh[31].qualifier_ui | Q000166 |
| mesh[31].descriptor_ui | D019579 |
| mesh[31].is_major_topic | True |
| mesh[31].qualifier_name | cytology |
| mesh[31].descriptor_name | Neocortex |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D051379 |
| mesh[32].is_major_topic | False |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Mice |
| mesh[33].qualifier_ui | Q000235 |
| mesh[33].descriptor_ui | D055495 |
| mesh[33].is_major_topic | True |
| mesh[33].qualifier_name | genetics |
| mesh[33].descriptor_name | Neurogenesis |
| mesh[34].qualifier_ui | Q000502 |
| mesh[34].descriptor_ui | D055495 |
| mesh[34].is_major_topic | True |
| mesh[34].qualifier_name | physiology |
| mesh[34].descriptor_name | Neurogenesis |
| mesh[35].qualifier_ui | Q000378 |
| mesh[35].descriptor_ui | D058953 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | metabolism |
| mesh[35].descriptor_name | Neural Stem Cells |
| mesh[36].qualifier_ui | Q000166 |
| mesh[36].descriptor_ui | D058953 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | cytology |
| mesh[36].descriptor_name | Neural Stem Cells |
| mesh[37].qualifier_ui | Q000378 |
| mesh[37].descriptor_ui | D034441 |
| mesh[37].is_major_topic | False |
| mesh[37].qualifier_name | metabolism |
| mesh[37].descriptor_name | Heterogeneous-Nuclear Ribonucleoproteins |
| mesh[38].qualifier_ui | Q000235 |
| mesh[38].descriptor_ui | D034441 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | genetics |
| mesh[38].descriptor_name | Heterogeneous-Nuclear Ribonucleoproteins |
| mesh[39].qualifier_ui | |
| mesh[39].descriptor_ui | D018345 |
| mesh[39].is_major_topic | False |
| mesh[39].qualifier_name | |
| mesh[39].descriptor_name | Mice, Knockout |
| mesh[40].qualifier_ui | Q000235 |
| mesh[40].descriptor_ui | D002454 |
| mesh[40].is_major_topic | False |
| mesh[40].qualifier_name | genetics |
| mesh[40].descriptor_name | Cell Differentiation |
| mesh[41].qualifier_ui | |
| mesh[41].descriptor_ui | D016601 |
| mesh[41].is_major_topic | False |
| mesh[41].qualifier_name | |
| mesh[41].descriptor_name | RNA-Binding Proteins |
| mesh[42].qualifier_ui | |
| mesh[42].descriptor_ui | D000818 |
| mesh[42].is_major_topic | False |
| mesh[42].qualifier_name | |
| mesh[42].descriptor_name | Animals |
| mesh[43].qualifier_ui | Q000378 |
| mesh[43].descriptor_ui | D019579 |
| mesh[43].is_major_topic | True |
| mesh[43].qualifier_name | metabolism |
| mesh[43].descriptor_name | Neocortex |
| mesh[44].qualifier_ui | Q000166 |
| mesh[44].descriptor_ui | D019579 |
| mesh[44].is_major_topic | True |
| mesh[44].qualifier_name | cytology |
| mesh[44].descriptor_name | Neocortex |
| mesh[45].qualifier_ui | |
| mesh[45].descriptor_ui | D051379 |
| mesh[45].is_major_topic | False |
| mesh[45].qualifier_name | |
| mesh[45].descriptor_name | Mice |
| mesh[46].qualifier_ui | Q000235 |
| mesh[46].descriptor_ui | D055495 |
| mesh[46].is_major_topic | True |
| mesh[46].qualifier_name | genetics |
| mesh[46].descriptor_name | Neurogenesis |
| mesh[47].qualifier_ui | Q000502 |
| mesh[47].descriptor_ui | D055495 |
| mesh[47].is_major_topic | True |
| mesh[47].qualifier_name | physiology |
| mesh[47].descriptor_name | Neurogenesis |
| mesh[48].qualifier_ui | Q000378 |
| mesh[48].descriptor_ui | D058953 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | metabolism |
| mesh[48].descriptor_name | Neural Stem Cells |
| mesh[49].qualifier_ui | Q000166 |
| mesh[49].descriptor_ui | D058953 |
| mesh[49].is_major_topic | False |
| mesh[49].qualifier_name | cytology |
| mesh[49].descriptor_name | Neural Stem Cells |
| type | article |
| title | Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip |
| awards[0].id | https://openalex.org/G2904601951 |
| awards[0].funder_id | https://openalex.org/F4320321001 |
| awards[0].display_name | |
| awards[0].funder_award_id | 32370883 |
| awards[0].funder_display_name | National Natural Science Foundation of China |
| awards[1].id | https://openalex.org/G413330150 |
| awards[1].funder_id | https://openalex.org/F4320336698 |
| awards[1].display_name | |
| awards[1].funder_award_id | BP0820029 |
| awards[1].funder_display_name | Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center) |
| biblio.issue | 8 |
| biblio.volume | 12 |
| biblio.last_page | e2411732 |
| biblio.first_page | e2411732 |
| topics[0].id | https://openalex.org/T10604 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1312 |
| topics[0].subfield.display_name | Molecular Biology |
| topics[0].display_name | RNA Research and Splicing |
| topics[1].id | https://openalex.org/T10062 |
| topics[1].field.id | https://openalex.org/fields/13 |
| topics[1].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[1].score | 0.9986000061035156 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1306 |
| topics[1].subfield.display_name | Cancer Research |
| topics[1].display_name | MicroRNA in disease regulation |
| topics[2].id | https://openalex.org/T11765 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9969000220298767 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | Circular RNAs in diseases |
| funders[0].id | https://openalex.org/F4320321001 |
| funders[0].ror | https://ror.org/01h0zpd94 |
| funders[0].display_name | National Natural Science Foundation of China |
| funders[1].id | https://openalex.org/F4320336698 |
| funders[1].ror | |
| funders[1].display_name | Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center) |
| is_xpac | False |
| apc_list.value | 5000 |
| apc_list.currency | USD |
| apc_list.value_usd | 5000 |
| apc_paid.value | 5000 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 5000 |
| concepts[0].id | https://openalex.org/C4746552 |
| concepts[0].level | 2 |
| concepts[0].score | 0.9485575556755066 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q1456827 |
| concepts[0].display_name | Neurogenesis |
| concepts[1].id | https://openalex.org/C2777222312 |
| concepts[1].level | 2 |
| concepts[1].score | 0.7443521022796631 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q726562 |
| concepts[1].display_name | Neocortex |
| concepts[2].id | https://openalex.org/C86803240 |
| concepts[2].level | 0 |
| concepts[2].score | 0.7091237902641296 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[2].display_name | Biology |
| concepts[3].id | https://openalex.org/C163952510 |
| concepts[3].level | 4 |
| concepts[3].score | 0.617214560508728 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q5058196 |
| concepts[3].display_name | Cell fate determination |
| concepts[4].id | https://openalex.org/C136834591 |
| concepts[4].level | 3 |
| concepts[4].score | 0.6099995374679565 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q2944097 |
| concepts[4].display_name | Neural stem cell |
| concepts[5].id | https://openalex.org/C169760540 |
| concepts[5].level | 1 |
| concepts[5].score | 0.5946997404098511 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q207011 |
| concepts[5].display_name | Neuroscience |
| concepts[6].id | https://openalex.org/C86339819 |
| concepts[6].level | 3 |
| concepts[6].score | 0.5127424001693726 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q407384 |
| concepts[6].display_name | Transcription factor |
| concepts[7].id | https://openalex.org/C95444343 |
| concepts[7].level | 1 |
| concepts[7].score | 0.4422937333583832 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7141 |
| concepts[7].display_name | Cell biology |
| concepts[8].id | https://openalex.org/C164659718 |
| concepts[8].level | 4 |
| concepts[8].score | 0.43387794494628906 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q5159266 |
| concepts[8].display_name | Conditional gene knockout |
| concepts[9].id | https://openalex.org/C63101894 |
| concepts[9].level | 4 |
| concepts[9].score | 0.4211848974227905 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q604095 |
| concepts[9].display_name | Fate mapping |
| concepts[10].id | https://openalex.org/C201750760 |
| concepts[10].level | 3 |
| concepts[10].score | 0.4169533848762512 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q1896218 |
| concepts[10].display_name | Progenitor cell |
| concepts[11].id | https://openalex.org/C28328180 |
| concepts[11].level | 2 |
| concepts[11].score | 0.2508186995983124 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q48196 |
| concepts[11].display_name | Stem cell |
| concepts[12].id | https://openalex.org/C104317684 |
| concepts[12].level | 2 |
| concepts[12].score | 0.1883704960346222 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[12].display_name | Gene |
| concepts[13].id | https://openalex.org/C54355233 |
| concepts[13].level | 1 |
| concepts[13].score | 0.15507933497428894 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[13].display_name | Genetics |
| concepts[14].id | https://openalex.org/C127716648 |
| concepts[14].level | 3 |
| concepts[14].score | 0.12850716710090637 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q104053 |
| concepts[14].display_name | Phenotype |
| keywords[0].id | https://openalex.org/keywords/neurogenesis |
| keywords[0].score | 0.9485575556755066 |
| keywords[0].display_name | Neurogenesis |
| keywords[1].id | https://openalex.org/keywords/neocortex |
| keywords[1].score | 0.7443521022796631 |
| keywords[1].display_name | Neocortex |
| keywords[2].id | https://openalex.org/keywords/biology |
| keywords[2].score | 0.7091237902641296 |
| keywords[2].display_name | Biology |
| keywords[3].id | https://openalex.org/keywords/cell-fate-determination |
| keywords[3].score | 0.617214560508728 |
| keywords[3].display_name | Cell fate determination |
| keywords[4].id | https://openalex.org/keywords/neural-stem-cell |
| keywords[4].score | 0.6099995374679565 |
| keywords[4].display_name | Neural stem cell |
| keywords[5].id | https://openalex.org/keywords/neuroscience |
| keywords[5].score | 0.5946997404098511 |
| keywords[5].display_name | Neuroscience |
| keywords[6].id | https://openalex.org/keywords/transcription-factor |
| keywords[6].score | 0.5127424001693726 |
| keywords[6].display_name | Transcription factor |
| keywords[7].id | https://openalex.org/keywords/cell-biology |
| keywords[7].score | 0.4422937333583832 |
| keywords[7].display_name | Cell biology |
| keywords[8].id | https://openalex.org/keywords/conditional-gene-knockout |
| keywords[8].score | 0.43387794494628906 |
| keywords[8].display_name | Conditional gene knockout |
| keywords[9].id | https://openalex.org/keywords/fate-mapping |
| keywords[9].score | 0.4211848974227905 |
| keywords[9].display_name | Fate mapping |
| keywords[10].id | https://openalex.org/keywords/progenitor-cell |
| keywords[10].score | 0.4169533848762512 |
| keywords[10].display_name | Progenitor cell |
| keywords[11].id | https://openalex.org/keywords/stem-cell |
| keywords[11].score | 0.2508186995983124 |
| keywords[11].display_name | Stem cell |
| keywords[12].id | https://openalex.org/keywords/gene |
| keywords[12].score | 0.1883704960346222 |
| keywords[12].display_name | Gene |
| keywords[13].id | https://openalex.org/keywords/genetics |
| keywords[13].score | 0.15507933497428894 |
| keywords[13].display_name | Genetics |
| keywords[14].id | https://openalex.org/keywords/phenotype |
| keywords[14].score | 0.12850716710090637 |
| keywords[14].display_name | Phenotype |
| language | en |
| locations[0].id | doi:10.1002/advs.202411732 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2737737698 |
| locations[0].source.issn | 2198-3844 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2198-3844 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Advanced Science |
| locations[0].source.host_organization | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_name | Wiley |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310320595 |
| locations[0].source.host_organization_lineage_names | Wiley |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Advanced Science |
| locations[0].landing_page_url | https://doi.org/10.1002/advs.202411732 |
| locations[1].id | pmid:39776340 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Advanced science (Weinheim, Baden-Wurttemberg, Germany) |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/39776340 |
| locations[2].id | pmh:oai:doaj.org/article:834fd38f2bab46db85ba1b402ce9fe25 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Advanced Science, Vol 12, Iss 8, Pp n/a-n/a (2025) |
| locations[2].landing_page_url | https://doaj.org/article/834fd38f2bab46db85ba1b402ce9fe25 |
| locations[3].id | pmh:oai:pubmedcentral.nih.gov:11848603 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S2764455111 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | PubMed Central |
| locations[3].source.host_organization | https://openalex.org/I1299303238 |
| locations[3].source.host_organization_name | National Institutes of Health |
| locations[3].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[3].license | other-oa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/other-oa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Adv Sci (Weinh) |
| locations[3].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11848603 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5028026003 |
| authorships[0].author.orcid | https://orcid.org/0009-0009-9257-8646 |
| authorships[0].author.display_name | Jiarui Wu |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[0].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[0].institutions[0].id | https://openalex.org/I200296433 |
| authorships[0].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Jiarui Wu |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[1].author.id | https://openalex.org/A5073708075 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-0748-9414 |
| authorships[1].author.display_name | Haoyang Yu |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[1].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[1].institutions[0].id | https://openalex.org/I200296433 |
| authorships[1].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Haoyang Yu |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[2].author.id | https://openalex.org/A5081403581 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-9601-7047 |
| authorships[2].author.display_name | Xiaowei Dou |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[2].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[2].institutions[0].id | https://openalex.org/I200296433 |
| authorships[2].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Xinyi Dou |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[3].author.id | https://openalex.org/A5050213589 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-1762-7585 |
| authorships[3].author.display_name | Bin Yin |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[3].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[3].institutions[0].id | https://openalex.org/I200296433 |
| authorships[3].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Bin Yin |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[4].author.id | https://openalex.org/A5045258292 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-7097-0876 |
| authorships[4].author.display_name | Hou‐Wen Lin |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[4].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[4].institutions[0].id | https://openalex.org/I200296433 |
| authorships[4].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Lin Hou |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[5].author.id | https://openalex.org/A5000073753 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Yuanchao Xue |
| authorships[5].countries | CN |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I19820366, https://openalex.org/I4210112540 |
| authorships[5].affiliations[0].raw_affiliation_string | Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101 China |
| authorships[5].institutions[0].id | https://openalex.org/I19820366 |
| authorships[5].institutions[0].ror | https://ror.org/034t30j35 |
| authorships[5].institutions[0].type | government |
| authorships[5].institutions[0].lineage | https://openalex.org/I19820366 |
| authorships[5].institutions[0].country_code | CN |
| authorships[5].institutions[0].display_name | Chinese Academy of Sciences |
| authorships[5].institutions[1].id | https://openalex.org/I4210112540 |
| authorships[5].institutions[1].ror | https://ror.org/01tyv8576 |
| authorships[5].institutions[1].type | facility |
| authorships[5].institutions[1].lineage | https://openalex.org/I19820366, https://openalex.org/I4210112540 |
| authorships[5].institutions[1].country_code | CN |
| authorships[5].institutions[1].display_name | Institute of Biophysics |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Yuanchao Xue |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101 China |
| authorships[6].author.id | https://openalex.org/A5103678747 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Boqin Qiang |
| authorships[6].countries | CN |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[6].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[6].institutions[0].id | https://openalex.org/I200296433 |
| authorships[6].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[6].institutions[0].country_code | CN |
| authorships[6].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Boqin Qiang |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[7].author.id | https://openalex.org/A5080390336 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-3091-2559 |
| authorships[7].author.display_name | Pengcheng Shu |
| authorships[7].countries | CN |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I200296433 |
| authorships[7].affiliations[0].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I4210115644 |
| authorships[7].affiliations[1].raw_affiliation_string | Chinese Institute for Brain Research, Beijing, 102206 China |
| authorships[7].institutions[0].id | https://openalex.org/I200296433 |
| authorships[7].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[7].institutions[0].country_code | CN |
| authorships[7].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[7].institutions[1].id | https://openalex.org/I4210115644 |
| authorships[7].institutions[1].ror | https://ror.org/029819q61 |
| authorships[7].institutions[1].type | government |
| authorships[7].institutions[1].lineage | https://openalex.org/I4210115644 |
| authorships[7].institutions[1].country_code | CN |
| authorships[7].institutions[1].display_name | Chinese Institute for Brain Research |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Pengcheng Shu |
| authorships[7].is_corresponding | True |
| authorships[7].raw_affiliation_strings | Chinese Institute for Brain Research, Beijing, 102206 China, State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[8].author.id | https://openalex.org/A5019309501 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-9592-9554 |
| authorships[8].author.display_name | Xiaozhong Peng |
| authorships[8].countries | CN |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I200296433, https://openalex.org/I4210131085 |
| authorships[8].affiliations[0].raw_affiliation_string | State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021 China |
| authorships[8].affiliations[1].institution_ids | https://openalex.org/I200296433 |
| authorships[8].affiliations[1].raw_affiliation_string | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China |
| authorships[8].institutions[0].id | https://openalex.org/I200296433 |
| authorships[8].institutions[0].ror | https://ror.org/02drdmm93 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I200296433 |
| authorships[8].institutions[0].country_code | CN |
| authorships[8].institutions[0].display_name | Chinese Academy of Medical Sciences & Peking Union Medical College |
| authorships[8].institutions[1].id | https://openalex.org/I4210131085 |
| authorships[8].institutions[1].ror | https://ror.org/038z7hb11 |
| authorships[8].institutions[1].type | facility |
| authorships[8].institutions[1].lineage | https://openalex.org/I4210131085, https://openalex.org/I4210141683 |
| authorships[8].institutions[1].country_code | CN |
| authorships[8].institutions[1].display_name | Institute of Laboratory Animal Science |
| authorships[8].author_position | last |
| authorships[8].raw_author_name | Xiaozhong Peng |
| authorships[8].is_corresponding | True |
| authorships[8].raw_affiliation_strings | State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry & Molecular Biology, Medical Primate Research Center, Neuroscience Center, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, 100005 China, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021 China |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.1002/advs.202411732 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Posttranscriptional Control of Neural Progenitors Temporal Dynamics During Neocortical Development by Syncrip |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10604 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1312 |
| primary_topic.subfield.display_name | Molecular Biology |
| primary_topic.display_name | RNA Research and Splicing |
| related_works | https://openalex.org/W2180812410, https://openalex.org/W2901458271, https://openalex.org/W2969998161, https://openalex.org/W4251701033, https://openalex.org/W2045980853, https://openalex.org/W131407539, https://openalex.org/W2941332545, https://openalex.org/W4200422867, https://openalex.org/W2159265403, https://openalex.org/W1140975977 |
| cited_by_count | 1 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| locations_count | 4 |
| best_oa_location.id | doi:10.1002/advs.202411732 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2737737698 |
| best_oa_location.source.issn | 2198-3844 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2198-3844 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Advanced Science |
| best_oa_location.source.host_organization | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_name | Wiley |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| best_oa_location.source.host_organization_lineage_names | Wiley |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Advanced Science |
| best_oa_location.landing_page_url | https://doi.org/10.1002/advs.202411732 |
| primary_location.id | doi:10.1002/advs.202411732 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2737737698 |
| primary_location.source.issn | 2198-3844 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2198-3844 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Advanced Science |
| primary_location.source.host_organization | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_name | Wiley |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310320595 |
| primary_location.source.host_organization_lineage_names | Wiley |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Advanced Science |
| primary_location.landing_page_url | https://doi.org/10.1002/advs.202411732 |
| publication_date | 2025-01-07 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W1981164058, https://openalex.org/W1988976106, https://openalex.org/W1967497564, https://openalex.org/W2944693844, https://openalex.org/W3175922295, https://openalex.org/W2944137180, https://openalex.org/W3174272230, https://openalex.org/W2225257929, https://openalex.org/W2099511737, https://openalex.org/W3005703665, https://openalex.org/W2167460636, https://openalex.org/W2138033133, https://openalex.org/W2506784803, https://openalex.org/W3154328670, https://openalex.org/W3093292403, https://openalex.org/W2902000867, https://openalex.org/W2581649032, https://openalex.org/W2806956737, https://openalex.org/W2292671099, https://openalex.org/W2164846750, https://openalex.org/W2303605232, https://openalex.org/W2065179254, https://openalex.org/W1996736819, https://openalex.org/W2135027010, https://openalex.org/W3135143003, https://openalex.org/W4210447846, https://openalex.org/W3173202634, https://openalex.org/W2023453764, https://openalex.org/W3092332391, https://openalex.org/W3171019759, https://openalex.org/W2022722148, https://openalex.org/W1921704775, https://openalex.org/W2092041178, https://openalex.org/W2760498857, https://openalex.org/W1965921323, https://openalex.org/W2117302968, https://openalex.org/W2785836753, https://openalex.org/W3213543422, https://openalex.org/W2759609596, https://openalex.org/W2147997023, https://openalex.org/W3114473647, https://openalex.org/W4292264352, https://openalex.org/W2810672236, https://openalex.org/W2615767183, https://openalex.org/W4366742718, https://openalex.org/W3021900349, https://openalex.org/W2114955073, https://openalex.org/W3213313835, https://openalex.org/W4387439798, https://openalex.org/W3045023537, https://openalex.org/W2791418880, https://openalex.org/W4308654581, https://openalex.org/W2946016273, https://openalex.org/W3096891241, https://openalex.org/W2898850951, https://openalex.org/W4381187055, https://openalex.org/W4307975131, https://openalex.org/W3192163773, https://openalex.org/W1964628768, https://openalex.org/W2793785833, https://openalex.org/W2735092275, https://openalex.org/W2124985265, https://openalex.org/W1968458420, https://openalex.org/W2964849163, https://openalex.org/W2152239989, https://openalex.org/W3036206386, https://openalex.org/W4226165246 |
| referenced_works_count | 67 |
| abstract_inverted_index.a | 47, 151 |
| abstract_inverted_index.Q) | 43 |
| abstract_inverted_index.an | 173 |
| abstract_inverted_index.as | 46, 74, 76, 150 |
| abstract_inverted_index.by | 10, 112 |
| abstract_inverted_index.in | 54, 59, 69, 81, 100, 135, 183 |
| abstract_inverted_index.is | 7, 44 |
| abstract_inverted_index.of | 3, 19, 50, 91, 107, 129, 153, 161, 166, 179 |
| abstract_inverted_index.to | 31, 142 |
| abstract_inverted_index.RNA | 84 |
| abstract_inverted_index.The | 1 |
| abstract_inverted_index.and | 63, 78, 163 |
| abstract_inverted_index.for | 176 |
| abstract_inverted_index.how | 23 |
| abstract_inverted_index.its | 138 |
| abstract_inverted_index.key | 48 |
| abstract_inverted_index.the | 4, 15, 37, 89, 94, 105, 121, 127, 158, 164 |
| abstract_inverted_index.yet | 14 |
| abstract_inverted_index.RGCs | 60, 162 |
| abstract_inverted_index.This | 170 |
| abstract_inverted_index.acts | 149 |
| abstract_inverted_index.deep | 30 |
| abstract_inverted_index.fate | 128, 159, 181 |
| abstract_inverted_index.form | 143 |
| abstract_inverted_index.gene | 12 |
| abstract_inverted_index.that | 88, 125 |
| abstract_inverted_index.well | 75 |
| abstract_inverted_index.Here, | 36 |
| abstract_inverted_index.Notch | 122 |
| abstract_inverted_index.RGCs. | 101, 130 |
| abstract_inverted_index.Thus, | 147 |
| abstract_inverted_index.cells | 26 |
| abstract_inverted_index.glial | 25 |
| abstract_inverted_index.hnRNP | 38 |
| abstract_inverted_index.human | 133 |
| abstract_inverted_index.layer | 72 |
| abstract_inverted_index.mice. | 82 |
| abstract_inverted_index.phase | 117 |
| abstract_inverted_index.study | 171 |
| abstract_inverted_index.(RGCs) | 27 |
| abstract_inverted_index.(hnRNP | 42 |
| abstract_inverted_index.family | 39 |
| abstract_inverted_index.member | 40 |
| abstract_inverted_index.memory | 79 |
| abstract_inverted_index.radial | 24 |
| abstract_inverted_index.remain | 34 |
| abstract_inverted_index.stable | 144 |
| abstract_inverted_index.weaken | 137 |
| abstract_inverted_index.Syncrip | 41, 57, 92, 103, 136, 148 |
| abstract_inverted_index.defects | 73 |
| abstract_inverted_index.factors | 111 |
| abstract_inverted_index.failing | 141 |
| abstract_inverted_index.pathway | 124 |
| abstract_inverted_index.through | 116 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.abnormal | 64 |
| abstract_inverted_index.analysis | 86 |
| abstract_inverted_index.cortical | 20, 71, 184 |
| abstract_inverted_index.disrupts | 61, 93 |
| abstract_inverted_index.generate | 29 |
| abstract_inverted_index.knockout | 58, 90 |
| abstract_inverted_index.learning | 77 |
| abstract_inverted_index.mediator | 152 |
| abstract_inverted_index.neuronal | 52, 65 |
| abstract_inverted_index.neurons, | 33 |
| abstract_inverted_index.stalling | 97 |
| abstract_inverted_index.temporal | 11, 16, 108, 168 |
| abstract_inverted_index.unclear. | 35 |
| abstract_inverted_index.complexes | 115, 145 |
| abstract_inverted_index.crucially | 119 |
| abstract_inverted_index.governing | 157 |
| abstract_inverted_index.intrinsic | 167 |
| abstract_inverted_index.maintains | 104 |
| abstract_inverted_index.mammalian | 5 |
| abstract_inverted_index.mechanism | 175 |
| abstract_inverted_index.modulator | 49 |
| abstract_inverted_index.mutations | 134 |
| abstract_inverted_index.neocortex | 6 |
| abstract_inverted_index.normally. | 146 |
| abstract_inverted_index.precisely | 8 |
| abstract_inverted_index.programs. | 169 |
| abstract_inverted_index.regulated | 9 |
| abstract_inverted_index.resulting | 68 |
| abstract_inverted_index.signaling | 123 |
| abstract_inverted_index.determines | 126 |
| abstract_inverted_index.identified | 45 |
| abstract_inverted_index.mechanisms | 18 |
| abstract_inverted_index.pathogenic | 132 |
| abstract_inverted_index.recruiting | 113 |
| abstract_inverted_index.regulating | 120 |
| abstract_inverted_index.regulation | 178 |
| abstract_inverted_index.regulatory | 17, 155 |
| abstract_inverted_index.sequencing | 85 |
| abstract_inverted_index.ultimately | 67 |
| abstract_inverted_index.advancement | 165 |
| abstract_inverted_index.capability, | 140 |
| abstract_inverted_index.development | 2 |
| abstract_inverted_index.establishes | 172 |
| abstract_inverted_index.expression, | 13 |
| abstract_inverted_index.impairments | 80 |
| abstract_inverted_index.mechanisms, | 156 |
| abstract_inverted_index.neocortical | 55 |
| abstract_inverted_index.progression | 99, 160 |
| abstract_inverted_index.progressive | 180 |
| abstract_inverted_index.separation, | 118 |
| abstract_inverted_index.superficial | 32, 51, 70 |
| abstract_inverted_index.Furthermore, | 131 |
| abstract_inverted_index.demonstrated | 87 |
| abstract_inverted_index.late‐stage | 95 |
| abstract_inverted_index.particularly | 22 |
| abstract_inverted_index.sequentially | 28 |
| abstract_inverted_index.Single‐cell | 83 |
| abstract_inverted_index.determination | 182 |
| abstract_inverted_index.intracellular | 174 |
| abstract_inverted_index.localization, | 66 |
| abstract_inverted_index.neurogenesis, | 21, 96 |
| abstract_inverted_index.neurogenesis. | 56, 185 |
| abstract_inverted_index.stabilization | 114 |
| abstract_inverted_index.transcription | 106, 110 |
| abstract_inverted_index.differentiation | 53, 62 |
| abstract_inverted_index.transcriptional | 98 |
| abstract_inverted_index.Mechanistically, | 102 |
| abstract_inverted_index.process‐related | 109 |
| abstract_inverted_index.phase‐separation | 139 |
| abstract_inverted_index.posttranscriptional | 154, 177 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| corresponding_author_ids | https://openalex.org/A5019309501, https://openalex.org/A5080390336 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 9 |
| corresponding_institution_ids | https://openalex.org/I200296433, https://openalex.org/I4210115644, https://openalex.org/I4210131085 |
| citation_normalized_percentile.value | 0.74094727 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |