Pre-pandemic SARS-CoV-2 serological reactivity in rural malaria-experienced Cambodians Article Swipe
Jessica E. Manning
,
Irfan Zaidi
,
Chanthap Lon
,
Luz Angela Rosas
,
Jae-Keun Park
,
Aiyana Ponce
,
Jennifer A. Bohl
,
Sophana Chea
,
Maria Karkanitsa
,
Sokunthea Sreng
,
Rekol Huy
,
Char Meng Chour
,
Dominic Esposito
,
Jeffery K. Taubenberger
,
Matthew J. Memoli
,
Kaitlyn Sadtler
,
Patrick E. Duffy
,
Fabiano Oliveira
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1101/2021.09.27.21264000
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1101/2021.09.27.21264000
Greater Mekong inhabitants are exposed to pathogens, zoonotic and otherwise, that may influence SARS-CoV-2 seroreactivity. A pre-pandemic (2005 to 2011) serosurvey of from 528 malaria-experienced Cambodians demonstrated higher-than-expected (up to 13.8 %) positivity of non-neutralizing IgG to SARS-CoV-2 spike and RBD antigens. These findings have implications for interpreting large-scale serosurveys. Article Summary Line In the pre-COVID19 pandemic years of 2005 to 2011, malaria experienced Cambodians from rural settings had higher-than-expected seroreactivity to SARS-CoV-2 spike and receptor binding domain proteins.
Related Topics
Concepts
Pandemic
Malaria
Serology
Coronavirus disease 2019 (COVID-19)
Virology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Medicine
Coronavirus
2019-20 coronavirus outbreak
Immunology
Antibody
Internal medicine
Outbreak
Infectious disease (medical specialty)
Disease
Metadata
- Type
- preprint
- Language
- en
- Landing Page
- https://doi.org/10.1101/2021.09.27.21264000
- https://www.medrxiv.org/content/medrxiv/early/2021/09/28/2021.09.27.21264000.full.pdf
- OA Status
- green
- Cited By
- 4
- References
- 22
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3203713090
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3203713090Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1101/2021.09.27.21264000Digital Object Identifier
- Title
-
Pre-pandemic SARS-CoV-2 serological reactivity in rural malaria-experienced CambodiansWork title
- Type
-
preprintOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-09-28Full publication date if available
- Authors
-
Jessica E. Manning, Irfan Zaidi, Chanthap Lon, Luz Angela Rosas, Jae-Keun Park, Aiyana Ponce, Jennifer A. Bohl, Sophana Chea, Maria Karkanitsa, Sokunthea Sreng, Rekol Huy, Char Meng Chour, Dominic Esposito, Jeffery K. Taubenberger, Matthew J. Memoli, Kaitlyn Sadtler, Patrick E. Duffy, Fabiano OliveiraList of authors in order
- Landing page
-
https://doi.org/10.1101/2021.09.27.21264000Publisher landing page
- PDF URL
-
https://www.medrxiv.org/content/medrxiv/early/2021/09/28/2021.09.27.21264000.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.medrxiv.org/content/medrxiv/early/2021/09/28/2021.09.27.21264000.full.pdfDirect OA link when available
- Concepts
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Pandemic, Malaria, Serology, Coronavirus disease 2019 (COVID-19), Virology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicine, Coronavirus, 2019-20 coronavirus outbreak, Immunology, Antibody, Internal medicine, Outbreak, Infectious disease (medical specialty), DiseaseTop concepts (fields/topics) attached by OpenAlex
- Cited by
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4Total citation count in OpenAlex
- Citations by year (recent)
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2022: 3, 2021: 1Per-year citation counts (last 5 years)
- References (count)
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22Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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