Precariousness Represents an Independent Risk Factor for Depression in Children With Sickle Cell Disease Article Swipe
Narcisse Elenga
,
Janaine Lony
,
Joddy Mafemamissindu
,
Noelis Thomas Boizan
,
Lindsay Osei
,
Mathieu Nacher
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1155/2024/1689091
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1155/2024/1689091
Importance: While the prevalence and impact of depression have been widely described in sickle cell disease, its relationship with precariousness has never been studied. Objective: This study aimed to describe the prevalence of depression and its relationship with clinical and demographic factors including social precariousness in children with sickle cell disease in French Guiana. Methods: We included children aged 12–18 years with sickle cell disease from the Sickle Cell Reference Center in French Guiana. A simple depression questionnaire “Child depression inventory 2” was proposed and completed by a clinical examination and consultation by a psychologist. Using the known assessment of health inequalities and poverty in health screening centres (EPICES) score, we developed a composite precariousness score that uses five items (each item is scored from 0 to 2). According to the chosen items, precariousness was defined as a score ≥5. Results: The prevalence of depression was 42.5% [95% CI: 31.5–54]. The median age was 15 years [95% CI: 13–17]. The age distribution peaked at 14 years in patients with depression. There were 76% of precarious patients in the depressed group and 18% in the control group ( p < 0.0001). In multivariate analysis, genotype SC (OR = 7.66, [1.17; 50.13], p = 0.0338) and precariousness (OR = 15.68, [4.73; 51.94], p < 0.0001) were associated with higher rates of depression. Baseline hemoglobin levels (OR = 0.48, [0.27; 0.88], p = 0.0173) were also associated with lower rates of depression. Conclusions and Relevance: Despite free healthcare, precariousness is an independent risk factor for depression.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1155/2024/1689091
- OA Status
- hybrid
- References
- 48
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4403735800
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- OpenAlex ID
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https://openalex.org/W4403735800Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1155/2024/1689091Digital Object Identifier
- Title
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Precariousness Represents an Independent Risk Factor for Depression in Children With Sickle Cell DiseaseWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-01-01Full publication date if available
- Authors
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Narcisse Elenga, Janaine Lony, Joddy Mafemamissindu, Noelis Thomas Boizan, Lindsay Osei, Mathieu NacherList of authors in order
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https://doi.org/10.1155/2024/1689091Publisher landing page
- Open access
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1155/2024/1689091Direct OA link when available
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Depression (economics), Disease, Risk factor, Psychiatry, Psychology, Medicine, Clinical psychology, Internal medicine, Macroeconomics, EconomicsTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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48Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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