Precision‐Arranged DNA Origami Plasmonic Nanoantennas for Multidimensional Smart‐Warning of Weightlessness Induced Bone Loss Article Swipe
Yufan Ling
,
Xuan Qin
,
Weijia Sun
,
Yue Fan
,
Yiwei Wang
,
Di Fan
,
Haoyuan Xu
,
Ruijie Xie
,
Jiawei Zhang
,
Jianwei Li
,
Bingyan Li
,
Yang Yang
,
Yingxian Li
,
Houyu Wang
,
Guangming Zhou
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1002/advs.202507189
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1002/advs.202507189
Surface‐Enhanced Raman Scattering (SERS) shows promise for monitoring health during space missions, particularly in assessing the effects of microgravity and radiation. However, traditional SERS sensors struggle with precise interfacial engineering, leading to a relatively poor assembly efficiency, and are unable to meet the practical needs of extreme spaceflight environments. To address this, it is designed and fabricated precision‐arranged DNA origami plasmonic nanoantennas. By leveraging DNA origami's addressability, it is built a 3 × 4 antenna array with a controlled spacing of 21.76 nm, enhancing assembly efficiency fourfold compared to disordered systems. The ordered system enabled accurate detection of calcium ions, interleukin‐6, and microRNA‐214 in serum from mice exposed to microgravity and radiation, with intraclass correlation coefficients > 0.75, comparable to ELISA and qPCR. More importantly, integrating the system with a convolutional neural network enabled precise bone health prediction. This platform provides a promising tool for astronaut health monitoring.
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/advs.202507189
- OA Status
- gold
- Cited By
- 1
- References
- 55
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4413101511
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4413101511Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1002/advs.202507189Digital Object Identifier
- Title
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Precision‐Arranged DNA Origami Plasmonic Nanoantennas for Multidimensional Smart‐Warning of Weightlessness Induced Bone LossWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-08-11Full publication date if available
- Authors
-
Yufan Ling, Xuan Qin, Weijia Sun, Yue Fan, Yiwei Wang, Di Fan, Haoyuan Xu, Ruijie Xie, Jiawei Zhang, Jianwei Li, Bingyan Li, Yang Yang, Yingxian Li, Houyu Wang, Guangming ZhouList of authors in order
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https://doi.org/10.1002/advs.202507189Publisher landing page
- Open access
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://doi.org/10.1002/advs.202507189Direct OA link when available
- Concepts
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Plasmon, Computer science, Nanotechnology, Materials science, Nanomedicine, Aerospace engineering, Nanoparticle, Optoelectronics, EngineeringTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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55Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.antenna | 75 |
| abstract_inverted_index.calcium | 99 |
| abstract_inverted_index.effects | 17 |
| abstract_inverted_index.enabled | 95, 134 |
| abstract_inverted_index.exposed | 108 |
| abstract_inverted_index.extreme | 47 |
| abstract_inverted_index.leading | 31 |
| abstract_inverted_index.network | 133 |
| abstract_inverted_index.ordered | 93 |
| abstract_inverted_index.origami | 60 |
| abstract_inverted_index.precise | 28, 135 |
| abstract_inverted_index.promise | 6 |
| abstract_inverted_index.sensors | 25 |
| abstract_inverted_index.spacing | 80 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.However, | 22 |
| abstract_inverted_index.accurate | 96 |
| abstract_inverted_index.assembly | 36, 85 |
| abstract_inverted_index.compared | 88 |
| abstract_inverted_index.designed | 55 |
| abstract_inverted_index.fourfold | 87 |
| abstract_inverted_index.platform | 140 |
| abstract_inverted_index.provides | 141 |
| abstract_inverted_index.struggle | 26 |
| abstract_inverted_index.systems. | 91 |
| abstract_inverted_index.assessing | 15 |
| abstract_inverted_index.astronaut | 146 |
| abstract_inverted_index.detection | 97 |
| abstract_inverted_index.enhancing | 84 |
| abstract_inverted_index.missions, | 12 |
| abstract_inverted_index.origami's | 66 |
| abstract_inverted_index.plasmonic | 61 |
| abstract_inverted_index.practical | 44 |
| abstract_inverted_index.promising | 143 |
| abstract_inverted_index.Scattering | 3 |
| abstract_inverted_index.comparable | 119 |
| abstract_inverted_index.controlled | 79 |
| abstract_inverted_index.disordered | 90 |
| abstract_inverted_index.efficiency | 86 |
| abstract_inverted_index.fabricated | 57 |
| abstract_inverted_index.intraclass | 114 |
| abstract_inverted_index.leveraging | 64 |
| abstract_inverted_index.monitoring | 8 |
| abstract_inverted_index.radiation, | 112 |
| abstract_inverted_index.radiation. | 21 |
| abstract_inverted_index.relatively | 34 |
| abstract_inverted_index.correlation | 115 |
| abstract_inverted_index.efficiency, | 37 |
| abstract_inverted_index.integrating | 126 |
| abstract_inverted_index.interfacial | 29 |
| abstract_inverted_index.monitoring. | 148 |
| abstract_inverted_index.prediction. | 138 |
| abstract_inverted_index.spaceflight | 48 |
| abstract_inverted_index.traditional | 23 |
| abstract_inverted_index.coefficients | 116 |
| abstract_inverted_index.engineering, | 30 |
| abstract_inverted_index.importantly, | 125 |
| abstract_inverted_index.microgravity | 19, 110 |
| abstract_inverted_index.particularly | 13 |
| abstract_inverted_index.convolutional | 131 |
| abstract_inverted_index.environments. | 49 |
| abstract_inverted_index.nanoantennas. | 62 |
| abstract_inverted_index.microRNA‐214 | 103 |
| abstract_inverted_index.addressability, | 67 |
| abstract_inverted_index.interleukin‐6, | 101 |
| abstract_inverted_index.Surface‐Enhanced | 1 |
| abstract_inverted_index.precision‐arranged | 58 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| corresponding_author_ids | https://openalex.org/A5033893564, https://openalex.org/A5006506036, https://openalex.org/A5100397670, https://openalex.org/A5016132929 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 15 |
| corresponding_institution_ids | https://openalex.org/I116953780, https://openalex.org/I3923682, https://openalex.org/I4210092495, https://openalex.org/I4210127126, https://openalex.org/I4210163738 |
| citation_normalized_percentile.value | 0.86261122 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |