Predictive value of extubation failure diagnosed by decrease in central venous oxygen saturation: a systematic review and meta-analysis Article Swipe
Chenxia Wu
,
Luoxia Hu
,
Qinkang Shen
,
Hua Xu
,
Haijun Huang
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-1647779/v1
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-1647779/v1
Background: The predictive power of extubation failure diagnosed by decrease in central venous oxygen saturation(ΔScvO2) varies by studies. Here we summarized the diagnostic value of extubation failure tested by ΔScvO2. Methods: A comprehensive online search was performed to select potentially eligible studies that evaluated the predictive power of extubation failure tested by ΔScvO2. A manual search was also performed to identify additional studies. Data were extracted to calculate the pooled sensitivity, specificity, positive likelihood ratio (LR),negative LR, diagnostic odds ratio (DOR), and area under the receiver operating characteristic curve (AUC) to evaluate the predictive power of extubation failure. Results: Overall, five studies including 353 patients were included in this review, of whom 105 (30%) were extubation failure. The cutoff values of ΔScvO2 varied across studies, ranging from 3.8% to 5.4%. Heterogeneity between studies was assessed with an overall Q = 0.007, I 2 = 0%, and P = 0.498. The pooled sensitivity and specificity for the overall population were 0.83 (95% CI: 0.74-0.90) and 0.88 (95% CI: 0.83-0.92), respectively. The pooled positive LR and negative LR were 7.2 (95%CI: 4.6-11.2) and 0.19 (95%CI: 0.12-0.31), respectively. The DOR was 38 (95% CI: 17–86). Overall, the pooled AUROC was 0.92 (95% CI: 0.90–0.94). Conclusions: The ΔScvO2 performed well in predicting extubation failure in adult mechanical ventilation patients.Further studies with a larger data set and well-designed models are required to confirm the diagnostic accuracy and utility of ScvO2 in predicting extubation outcomes in mechanical ventilation patients.
Related Topics
Concepts
Medicine
Diagnostic odds ratio
Meta-analysis
Receiver operating characteristic
Odds ratio
Mechanical ventilation
Likelihood ratios in diagnostic testing
Area under the curve
Internal medicine
Cutoff
Confidence interval
Population
Pooled variance
Positive predicative value
Predictive value of tests
Predictive value
Surgery
Environmental health
Physics
Quantum mechanics
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-1647779/v1
- https://www.researchsquare.com/article/rs-1647779/latest.pdf
- OA Status
- green
- References
- 18
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4280617463
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4280617463Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.21203/rs.3.rs-1647779/v1Digital Object Identifier
- Title
-
Predictive value of extubation failure diagnosed by decrease in central venous oxygen saturation: a systematic review and meta-analysisWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-05-17Full publication date if available
- Authors
-
Chenxia Wu, Luoxia Hu, Qinkang Shen, Hua Xu, Haijun HuangList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.3.rs-1647779/v1Publisher landing page
- PDF URL
-
https://www.researchsquare.com/article/rs-1647779/latest.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
greenOpen access status per OpenAlex
- OA URL
-
https://www.researchsquare.com/article/rs-1647779/latest.pdfDirect OA link when available
- Concepts
-
Medicine, Diagnostic odds ratio, Meta-analysis, Receiver operating characteristic, Odds ratio, Mechanical ventilation, Likelihood ratios in diagnostic testing, Area under the curve, Internal medicine, Cutoff, Confidence interval, Population, Pooled variance, Positive predicative value, Predictive value of tests, Predictive value, Surgery, Environmental health, Physics, Quantum mechanicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
18Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4280617463 |
|---|---|
| doi | https://doi.org/10.21203/rs.3.rs-1647779/v1 |
| ids.doi | https://doi.org/10.21203/rs.3.rs-1647779/v1 |
| ids.openalex | https://openalex.org/W4280617463 |
| fwci | 0.0 |
| type | review |
| title | Predictive value of extubation failure diagnosed by decrease in central venous oxygen saturation: a systematic review and meta-analysis |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T10322 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9979000091552734 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2740 |
| topics[0].subfield.display_name | Pulmonary and Respiratory Medicine |
| topics[0].display_name | Respiratory Support and Mechanisms |
| topics[1].id | https://openalex.org/T10218 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9908000230789185 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2713 |
| topics[1].subfield.display_name | Epidemiology |
| topics[1].display_name | Sepsis Diagnosis and Treatment |
| topics[2].id | https://openalex.org/T10830 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9901000261306763 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2703 |
| topics[2].subfield.display_name | Anesthesiology and Pain Medicine |
| topics[2].display_name | Airway Management and Intubation Techniques |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.7515721321105957 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C157481446 |
| concepts[1].level | 3 |
| concepts[1].score | 0.7455118298530579 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q5270351 |
| concepts[1].display_name | Diagnostic odds ratio |
| concepts[2].id | https://openalex.org/C95190672 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6901742219924927 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q815382 |
| concepts[2].display_name | Meta-analysis |
| concepts[3].id | https://openalex.org/C58471807 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6610088348388672 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q327120 |
| concepts[3].display_name | Receiver operating characteristic |
| concepts[4].id | https://openalex.org/C156957248 |
| concepts[4].level | 2 |
| concepts[4].score | 0.6120085120201111 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q1862216 |
| concepts[4].display_name | Odds ratio |
| concepts[5].id | https://openalex.org/C2777080012 |
| concepts[5].level | 2 |
| concepts[5].score | 0.606239378452301 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q3766250 |
| concepts[5].display_name | Mechanical ventilation |
| concepts[6].id | https://openalex.org/C144494922 |
| concepts[6].level | 3 |
| concepts[6].score | 0.579714834690094 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q6547272 |
| concepts[6].display_name | Likelihood ratios in diagnostic testing |
| concepts[7].id | https://openalex.org/C76318530 |
| concepts[7].level | 2 |
| concepts[7].score | 0.5403357744216919 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q16833590 |
| concepts[7].display_name | Area under the curve |
| concepts[8].id | https://openalex.org/C126322002 |
| concepts[8].level | 1 |
| concepts[8].score | 0.5362915396690369 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[8].display_name | Internal medicine |
| concepts[9].id | https://openalex.org/C2778217198 |
| concepts[9].level | 2 |
| concepts[9].score | 0.523112952709198 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q556977 |
| concepts[9].display_name | Cutoff |
| concepts[10].id | https://openalex.org/C44249647 |
| concepts[10].level | 2 |
| concepts[10].score | 0.47726982831954956 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q208498 |
| concepts[10].display_name | Confidence interval |
| concepts[11].id | https://openalex.org/C2908647359 |
| concepts[11].level | 2 |
| concepts[11].score | 0.47689583897590637 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q2625603 |
| concepts[11].display_name | Population |
| concepts[12].id | https://openalex.org/C143781015 |
| concepts[12].level | 3 |
| concepts[12].score | 0.44467946887016296 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7228635 |
| concepts[12].display_name | Pooled variance |
| concepts[13].id | https://openalex.org/C53789813 |
| concepts[13].level | 3 |
| concepts[13].score | 0.4329088628292084 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q3553769 |
| concepts[13].display_name | Positive predicative value |
| concepts[14].id | https://openalex.org/C198433322 |
| concepts[14].level | 2 |
| concepts[14].score | 0.42798590660095215 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q3910099 |
| concepts[14].display_name | Predictive value of tests |
| concepts[15].id | https://openalex.org/C3019719930 |
| concepts[15].level | 2 |
| concepts[15].score | 0.40875884890556335 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q3910099 |
| concepts[15].display_name | Predictive value |
| concepts[16].id | https://openalex.org/C141071460 |
| concepts[16].level | 1 |
| concepts[16].score | 0.34109795093536377 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q40821 |
| concepts[16].display_name | Surgery |
| concepts[17].id | https://openalex.org/C99454951 |
| concepts[17].level | 1 |
| concepts[17].score | 0.0 |
| concepts[17].wikidata | https://www.wikidata.org/wiki/Q932068 |
| concepts[17].display_name | Environmental health |
| concepts[18].id | https://openalex.org/C121332964 |
| concepts[18].level | 0 |
| concepts[18].score | 0.0 |
| concepts[18].wikidata | https://www.wikidata.org/wiki/Q413 |
| concepts[18].display_name | Physics |
| concepts[19].id | https://openalex.org/C62520636 |
| concepts[19].level | 1 |
| concepts[19].score | 0.0 |
| concepts[19].wikidata | https://www.wikidata.org/wiki/Q944 |
| concepts[19].display_name | Quantum mechanics |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.7515721321105957 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/diagnostic-odds-ratio |
| keywords[1].score | 0.7455118298530579 |
| keywords[1].display_name | Diagnostic odds ratio |
| keywords[2].id | https://openalex.org/keywords/meta-analysis |
| keywords[2].score | 0.6901742219924927 |
| keywords[2].display_name | Meta-analysis |
| keywords[3].id | https://openalex.org/keywords/receiver-operating-characteristic |
| keywords[3].score | 0.6610088348388672 |
| keywords[3].display_name | Receiver operating characteristic |
| keywords[4].id | https://openalex.org/keywords/odds-ratio |
| keywords[4].score | 0.6120085120201111 |
| keywords[4].display_name | Odds ratio |
| keywords[5].id | https://openalex.org/keywords/mechanical-ventilation |
| keywords[5].score | 0.606239378452301 |
| keywords[5].display_name | Mechanical ventilation |
| keywords[6].id | https://openalex.org/keywords/likelihood-ratios-in-diagnostic-testing |
| keywords[6].score | 0.579714834690094 |
| keywords[6].display_name | Likelihood ratios in diagnostic testing |
| keywords[7].id | https://openalex.org/keywords/area-under-the-curve |
| keywords[7].score | 0.5403357744216919 |
| keywords[7].display_name | Area under the curve |
| keywords[8].id | https://openalex.org/keywords/internal-medicine |
| keywords[8].score | 0.5362915396690369 |
| keywords[8].display_name | Internal medicine |
| keywords[9].id | https://openalex.org/keywords/cutoff |
| keywords[9].score | 0.523112952709198 |
| keywords[9].display_name | Cutoff |
| keywords[10].id | https://openalex.org/keywords/confidence-interval |
| keywords[10].score | 0.47726982831954956 |
| keywords[10].display_name | Confidence interval |
| keywords[11].id | https://openalex.org/keywords/population |
| keywords[11].score | 0.47689583897590637 |
| keywords[11].display_name | Population |
| keywords[12].id | https://openalex.org/keywords/pooled-variance |
| keywords[12].score | 0.44467946887016296 |
| keywords[12].display_name | Pooled variance |
| keywords[13].id | https://openalex.org/keywords/positive-predicative-value |
| keywords[13].score | 0.4329088628292084 |
| keywords[13].display_name | Positive predicative value |
| keywords[14].id | https://openalex.org/keywords/predictive-value-of-tests |
| keywords[14].score | 0.42798590660095215 |
| keywords[14].display_name | Predictive value of tests |
| keywords[15].id | https://openalex.org/keywords/predictive-value |
| keywords[15].score | 0.40875884890556335 |
| keywords[15].display_name | Predictive value |
| keywords[16].id | https://openalex.org/keywords/surgery |
| keywords[16].score | 0.34109795093536377 |
| keywords[16].display_name | Surgery |
| language | en |
| locations[0].id | doi:10.21203/rs.3.rs-1647779/v1 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4306402450 |
| locations[0].source.issn | |
| locations[0].source.type | repository |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | |
| locations[0].source.is_core | False |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Research Square (Research Square) |
| locations[0].source.host_organization | https://openalex.org/I4210096694 |
| locations[0].source.host_organization_name | Research Square (United States) |
| locations[0].source.host_organization_lineage | https://openalex.org/I4210096694 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.researchsquare.com/article/rs-1647779/latest.pdf |
| locations[0].version | acceptedVersion |
| locations[0].raw_type | posted-content |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | False |
| locations[0].raw_source_name | |
| locations[0].landing_page_url | https://doi.org/10.21203/rs.3.rs-1647779/v1 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5115592740 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-5624-1546 |
| authorships[0].author.display_name | Chenxia Wu |
| authorships[0].countries | CN |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I114539943 |
| authorships[0].affiliations[0].raw_affiliation_string | Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I114539943 |
| authorships[0].affiliations[1].raw_affiliation_string | Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[0].affiliations[2].institution_ids | https://openalex.org/I114539943 |
| authorships[0].affiliations[2].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[0].affiliations[3].institution_ids | https://openalex.org/I114539943 |
| authorships[0].affiliations[3].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research |
| authorships[0].institutions[0].id | https://openalex.org/I114539943 |
| authorships[0].institutions[0].ror | https://ror.org/04epb4p87 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I114539943 |
| authorships[0].institutions[0].country_code | CN |
| authorships[0].institutions[0].display_name | Zhejiang Chinese Medical University |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Chenxia Wu |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University, Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research, Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University, Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[1].author.id | https://openalex.org/A5038941968 |
| authorships[1].author.orcid | |
| authorships[1].author.display_name | Luoxia Hu |
| authorships[1].countries | CN |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I114539943 |
| authorships[1].affiliations[0].raw_affiliation_string | Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[1].affiliations[1].institution_ids | https://openalex.org/I114539943 |
| authorships[1].affiliations[1].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[1].affiliations[2].institution_ids | https://openalex.org/I114539943 |
| authorships[1].affiliations[2].raw_affiliation_string | Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University |
| authorships[1].affiliations[3].institution_ids | https://openalex.org/I114539943 |
| authorships[1].affiliations[3].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research |
| authorships[1].institutions[0].id | https://openalex.org/I114539943 |
| authorships[1].institutions[0].ror | https://ror.org/04epb4p87 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I114539943 |
| authorships[1].institutions[0].country_code | CN |
| authorships[1].institutions[0].display_name | Zhejiang Chinese Medical University |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Luoxia Hu |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University, Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research, Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University, Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[2].author.id | https://openalex.org/A5022538763 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Qinkang Shen |
| authorships[2].countries | CN |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I114539943 |
| authorships[2].affiliations[0].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research |
| authorships[2].affiliations[1].institution_ids | https://openalex.org/I114539943 |
| authorships[2].affiliations[1].raw_affiliation_string | Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[2].affiliations[2].institution_ids | https://openalex.org/I114539943 |
| authorships[2].affiliations[2].raw_affiliation_string | Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University |
| authorships[2].affiliations[3].institution_ids | https://openalex.org/I114539943 |
| authorships[2].affiliations[3].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[2].institutions[0].id | https://openalex.org/I114539943 |
| authorships[2].institutions[0].ror | https://ror.org/04epb4p87 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I114539943 |
| authorships[2].institutions[0].country_code | CN |
| authorships[2].institutions[0].display_name | Zhejiang Chinese Medical University |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Qinkang Shen |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University, Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research, Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University, Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[3].author.id | https://openalex.org/A5101412755 |
| authorships[3].author.orcid | https://orcid.org/0009-0008-9988-3291 |
| authorships[3].author.display_name | Hua Xu |
| authorships[3].countries | CN |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I114539943 |
| authorships[3].affiliations[0].raw_affiliation_string | Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University |
| authorships[3].affiliations[1].institution_ids | https://openalex.org/I114539943 |
| authorships[3].affiliations[1].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[3].affiliations[2].institution_ids | https://openalex.org/I114539943 |
| authorships[3].affiliations[2].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research |
| authorships[3].affiliations[3].institution_ids | https://openalex.org/I114539943 |
| authorships[3].affiliations[3].raw_affiliation_string | Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[3].institutions[0].id | https://openalex.org/I114539943 |
| authorships[3].institutions[0].ror | https://ror.org/04epb4p87 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I114539943 |
| authorships[3].institutions[0].country_code | CN |
| authorships[3].institutions[0].display_name | Zhejiang Chinese Medical University |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Hua Xu |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University, Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research, Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University, Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[4].author.id | https://openalex.org/A5053853169 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-2591-8729 |
| authorships[4].author.display_name | Haijun Huang |
| authorships[4].countries | CN |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I114539943 |
| authorships[4].affiliations[0].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I114539943 |
| authorships[4].affiliations[1].raw_affiliation_string | Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University |
| authorships[4].affiliations[2].institution_ids | https://openalex.org/I114539943 |
| authorships[4].affiliations[2].raw_affiliation_string | Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[4].affiliations[3].institution_ids | https://openalex.org/I114539943 |
| authorships[4].affiliations[3].raw_affiliation_string | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| authorships[4].institutions[0].id | https://openalex.org/I114539943 |
| authorships[4].institutions[0].ror | https://ror.org/04epb4p87 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I114539943 |
| authorships[4].institutions[0].country_code | CN |
| authorships[4].institutions[0].display_name | Zhejiang Chinese Medical University |
| authorships[4].author_position | last |
| authorships[4].raw_author_name | Haijun Huang |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University, Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University Research, Emergency Department,The First Affiliated Hospital of Zhejiang Chinese Medical University, Luoxia Hu Emergency Department,The First A liated Hospital of Zhejiang Chinese Medical University |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.researchsquare.com/article/rs-1647779/latest.pdf |
| open_access.oa_status | green |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Predictive value of extubation failure diagnosed by decrease in central venous oxygen saturation: a systematic review and meta-analysis |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10322 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9979000091552734 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2740 |
| primary_topic.subfield.display_name | Pulmonary and Respiratory Medicine |
| primary_topic.display_name | Respiratory Support and Mechanisms |
| related_works | https://openalex.org/W2903426880, https://openalex.org/W2369690752, https://openalex.org/W2016457032, https://openalex.org/W2790008348, https://openalex.org/W2907414186, https://openalex.org/W2036972161, https://openalex.org/W2064349045, https://openalex.org/W2486647127, https://openalex.org/W2037653269, https://openalex.org/W2944750878 |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.21203/rs.3.rs-1647779/v1 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4306402450 |
| best_oa_location.source.issn | |
| best_oa_location.source.type | repository |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Research Square (Research Square) |
| best_oa_location.source.host_organization | https://openalex.org/I4210096694 |
| best_oa_location.source.host_organization_name | Research Square (United States) |
| best_oa_location.source.host_organization_lineage | https://openalex.org/I4210096694 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.researchsquare.com/article/rs-1647779/latest.pdf |
| best_oa_location.version | acceptedVersion |
| best_oa_location.raw_type | posted-content |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | |
| best_oa_location.landing_page_url | https://doi.org/10.21203/rs.3.rs-1647779/v1 |
| primary_location.id | doi:10.21203/rs.3.rs-1647779/v1 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4306402450 |
| primary_location.source.issn | |
| primary_location.source.type | repository |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | |
| primary_location.source.is_core | False |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Research Square (Research Square) |
| primary_location.source.host_organization | https://openalex.org/I4210096694 |
| primary_location.source.host_organization_name | Research Square (United States) |
| primary_location.source.host_organization_lineage | https://openalex.org/I4210096694 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.researchsquare.com/article/rs-1647779/latest.pdf |
| primary_location.version | acceptedVersion |
| primary_location.raw_type | posted-content |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | False |
| primary_location.raw_source_name | |
| primary_location.landing_page_url | https://doi.org/10.21203/rs.3.rs-1647779/v1 |
| publication_date | 2022-05-17 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W2502274362, https://openalex.org/W2042878027, https://openalex.org/W1603519426, https://openalex.org/W2073079549, https://openalex.org/W2978081422, https://openalex.org/W2092926517, https://openalex.org/W1969162117, https://openalex.org/W2093579014, https://openalex.org/W2129015321, https://openalex.org/W2094786624, https://openalex.org/W2041468256, https://openalex.org/W2149809698, https://openalex.org/W4236476849, https://openalex.org/W4241883466, https://openalex.org/W2081516016, https://openalex.org/W4243841242, https://openalex.org/W2156098321, https://openalex.org/W2518493950 |
| referenced_works_count | 18 |
| abstract_inverted_index.2 | 143 |
| abstract_inverted_index.= | 140, 144, 148 |
| abstract_inverted_index.A | 32, 54 |
| abstract_inverted_index.I | 142 |
| abstract_inverted_index.P | 147 |
| abstract_inverted_index.Q | 139 |
| abstract_inverted_index.a | 218 |
| abstract_inverted_index.38 | 189 |
| abstract_inverted_index.LR | 173, 176 |
| abstract_inverted_index.an | 137 |
| abstract_inverted_index.by | 9, 17, 29, 52 |
| abstract_inverted_index.in | 11, 108, 207, 211, 236, 240 |
| abstract_inverted_index.of | 5, 25, 48, 96, 111, 121, 234 |
| abstract_inverted_index.to | 38, 60, 67, 91, 129, 227 |
| abstract_inverted_index.we | 20 |
| abstract_inverted_index.0%, | 145 |
| abstract_inverted_index.105 | 113 |
| abstract_inverted_index.353 | 104 |
| abstract_inverted_index.7.2 | 178 |
| abstract_inverted_index.CI: | 162, 167, 191, 200 |
| abstract_inverted_index.DOR | 187 |
| abstract_inverted_index.LR, | 77 |
| abstract_inverted_index.The | 2, 118, 150, 170, 186, 203 |
| abstract_inverted_index.and | 82, 146, 153, 164, 174, 181, 222, 232 |
| abstract_inverted_index.are | 225 |
| abstract_inverted_index.for | 155 |
| abstract_inverted_index.set | 221 |
| abstract_inverted_index.the | 22, 45, 69, 85, 93, 156, 194, 229 |
| abstract_inverted_index.was | 36, 57, 134, 188, 197 |
| abstract_inverted_index.(95% | 161, 166, 190, 199 |
| abstract_inverted_index.0.19 | 182 |
| abstract_inverted_index.0.83 | 160 |
| abstract_inverted_index.0.88 | 165 |
| abstract_inverted_index.0.92 | 198 |
| abstract_inverted_index.3.8% | 128 |
| abstract_inverted_index.Data | 64 |
| abstract_inverted_index.Here | 19 |
| abstract_inverted_index.also | 58 |
| abstract_inverted_index.area | 83 |
| abstract_inverted_index.data | 220 |
| abstract_inverted_index.five | 101 |
| abstract_inverted_index.from | 127 |
| abstract_inverted_index.odds | 79 |
| abstract_inverted_index.that | 43 |
| abstract_inverted_index.this | 109 |
| abstract_inverted_index.well | 206 |
| abstract_inverted_index.were | 65, 106, 115, 159, 177 |
| abstract_inverted_index.whom | 112 |
| abstract_inverted_index.with | 136, 217 |
| abstract_inverted_index.(30%) | 114 |
| abstract_inverted_index.(AUC) | 90 |
| abstract_inverted_index.5.4%. | 130 |
| abstract_inverted_index.AUROC | 196 |
| abstract_inverted_index.ScvO2 | 235 |
| abstract_inverted_index.adult | 212 |
| abstract_inverted_index.curve | 89 |
| abstract_inverted_index.power | 4, 47, 95 |
| abstract_inverted_index.ratio | 75, 80 |
| abstract_inverted_index.under | 84 |
| abstract_inverted_index.value | 24 |
| abstract_inverted_index.(DOR), | 81 |
| abstract_inverted_index.0.007, | 141 |
| abstract_inverted_index.0.498. | 149 |
| abstract_inverted_index.across | 124 |
| abstract_inverted_index.cutoff | 119 |
| abstract_inverted_index.larger | 219 |
| abstract_inverted_index.manual | 55 |
| abstract_inverted_index.models | 224 |
| abstract_inverted_index.online | 34 |
| abstract_inverted_index.oxygen | 14 |
| abstract_inverted_index.pooled | 70, 151, 171, 195 |
| abstract_inverted_index.search | 35, 56 |
| abstract_inverted_index.select | 39 |
| abstract_inverted_index.tested | 28, 51 |
| abstract_inverted_index.values | 120 |
| abstract_inverted_index.varied | 123 |
| abstract_inverted_index.varies | 16 |
| abstract_inverted_index.venous | 13 |
| abstract_inverted_index.(95%CI: | 179, 183 |
| abstract_inverted_index.between | 132 |
| abstract_inverted_index.central | 12 |
| abstract_inverted_index.confirm | 228 |
| abstract_inverted_index.failure | 7, 27, 50, 210 |
| abstract_inverted_index.overall | 138, 157 |
| abstract_inverted_index.ranging | 126 |
| abstract_inverted_index.review, | 110 |
| abstract_inverted_index.studies | 42, 102, 133, 216 |
| abstract_inverted_index.utility | 233 |
| abstract_inverted_index.ΔScvO2 | 122, 204 |
| abstract_inverted_index.Abstract | 0 |
| abstract_inverted_index.Methods: | 31 |
| abstract_inverted_index.Overall, | 100, 193 |
| abstract_inverted_index.Results: | 99 |
| abstract_inverted_index.accuracy | 231 |
| abstract_inverted_index.assessed | 135 |
| abstract_inverted_index.decrease | 10 |
| abstract_inverted_index.eligible | 41 |
| abstract_inverted_index.evaluate | 92 |
| abstract_inverted_index.failure. | 98, 117 |
| abstract_inverted_index.identify | 61 |
| abstract_inverted_index.included | 107 |
| abstract_inverted_index.negative | 175 |
| abstract_inverted_index.outcomes | 239 |
| abstract_inverted_index.patients | 105 |
| abstract_inverted_index.positive | 73, 172 |
| abstract_inverted_index.receiver | 86 |
| abstract_inverted_index.required | 226 |
| abstract_inverted_index.studies, | 125 |
| abstract_inverted_index.studies. | 18, 63 |
| abstract_inverted_index.ΔScvO2. | 30, 53 |
| abstract_inverted_index.17–86). | 192 |
| abstract_inverted_index.4.6-11.2) | 180 |
| abstract_inverted_index.calculate | 68 |
| abstract_inverted_index.diagnosed | 8 |
| abstract_inverted_index.evaluated | 44 |
| abstract_inverted_index.extracted | 66 |
| abstract_inverted_index.including | 103 |
| abstract_inverted_index.operating | 87 |
| abstract_inverted_index.patients. | 243 |
| abstract_inverted_index.performed | 37, 59, 205 |
| abstract_inverted_index.0.74-0.90) | 163 |
| abstract_inverted_index.additional | 62 |
| abstract_inverted_index.diagnostic | 23, 78, 230 |
| abstract_inverted_index.extubation | 6, 26, 49, 97, 116, 209, 238 |
| abstract_inverted_index.likelihood | 74 |
| abstract_inverted_index.mechanical | 213, 241 |
| abstract_inverted_index.population | 158 |
| abstract_inverted_index.predicting | 208, 237 |
| abstract_inverted_index.predictive | 3, 46, 94 |
| abstract_inverted_index.summarized | 21 |
| abstract_inverted_index.0.12-0.31), | 184 |
| abstract_inverted_index.0.83-0.92), | 168 |
| abstract_inverted_index.Background: | 1 |
| abstract_inverted_index.potentially | 40 |
| abstract_inverted_index.sensitivity | 152 |
| abstract_inverted_index.specificity | 154 |
| abstract_inverted_index.ventilation | 214, 242 |
| abstract_inverted_index.Conclusions: | 202 |
| abstract_inverted_index.sensitivity, | 71 |
| abstract_inverted_index.specificity, | 72 |
| abstract_inverted_index.(LR),negative | 76 |
| abstract_inverted_index.0.90–0.94). | 201 |
| abstract_inverted_index.Heterogeneity | 131 |
| abstract_inverted_index.comprehensive | 33 |
| abstract_inverted_index.respectively. | 169, 185 |
| abstract_inverted_index.well-designed | 223 |
| abstract_inverted_index.characteristic | 88 |
| abstract_inverted_index.patients.Further | 215 |
| abstract_inverted_index.saturation(ΔScvO2) | 15 |
| cited_by_percentile_year | |
| countries_distinct_count | 1 |
| institutions_distinct_count | 5 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.41999998688697815 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.10301874 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |