Predictive Value of Frailty Index in Comparison to Traditional Markers of Sepsis in Predicting Mortality among Elderly Admitted in Tertiary Care Hospital Article Swipe
Ashwariya Murlidharan
,
Minakshi Dhar
,
Monika Pathania
,
Mayank Agarwal
,
Prativa Priyadarshani Sethi
,
Vartika Saxena
,
Nowneet Kumar Bhat
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.5005/japi-11001-0094
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.5005/japi-11001-0094
Introduction: The frailty index’s potential as a prognostic marker of sepsis is so far been untapped. Here we studied the predictive value of frailty index in the elderly with sepsis. Methods: This prospective cohort study was conducted in a tertiary level hospital in North India. The duration of the study was 18 months starting from January 2020 to July 2021. The frailty index was calculated along with traditional markers of sepsis such as sequential organ failure assessment (SOFA), quick sequential organ failure assessment (qSOFA), and systemic inflammatory response syndrome (SIRS) within 24 hours of admission in elderly patients suspected to have sepsis. The area under the receiver operating characteristic (AUROC) of frailty index, SOFA, qSOFA, and SIRS was compared for in-hospital and 3-month mortality. Results: There was no significant difference between the performance of the frailty index and SOFA (DeLong’s test p = 0.242) in predicting in-hospital mortality, but there was a statistical difference between the AUROC of SOFA score (AUC = 0.548) and frailty in predicting 3-month mortality (DeLong’s test p ≤0.001). Conclusion: The frailty index had greater sensitivity and negative predictive value among the other scores in predicting in-hospital mortality, whereas SOFA had higher specificity in predicting in-hospital mortality. The frailty index was superior to SOFA and the other prognostic markers of sepsis in predicting 3-month mortality
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.5005/japi-11001-0094
- https://doi.org/10.5005/japi-11001-0094
- OA Status
- bronze
- Cited By
- 6
- References
- 15
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4295078831
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4295078831Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.5005/japi-11001-0094Digital Object Identifier
- Title
-
Predictive Value of Frailty Index in Comparison to Traditional Markers of Sepsis in Predicting Mortality among Elderly Admitted in Tertiary Care HospitalWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
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2022Year of publication
- Publication date
-
2022-09-01Full publication date if available
- Authors
-
Ashwariya Murlidharan, Minakshi Dhar, Monika Pathania, Mayank Agarwal, Prativa Priyadarshani Sethi, Vartika Saxena, Nowneet Kumar BhatList of authors in order
- Landing page
-
https://doi.org/10.5005/japi-11001-0094Publisher landing page
- PDF URL
-
https://doi.org/10.5005/japi-11001-0094Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.5005/japi-11001-0094Direct OA link when available
- Concepts
-
Medicine, Sepsis, SOFA score, Receiver operating characteristic, Systemic inflammatory response syndrome, Frailty Index, Internal medicine, Prospective cohort study, Cohort, Cohort study, Predictive value of tests, Emergency medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
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6Total citation count in OpenAlex
- Citations by year (recent)
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2025: 3, 2023: 1, 2022: 2Per-year citation counts (last 5 years)
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15Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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