Predictors of cognitive dysfunction after cardiac surgery: a systematic review Article Swipe
Tracey Bowden
,
Catherine S. Hurt
,
Julie Sanders
,
Leanne M. Aitken
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1093/eurjcn/zvab086
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1093/eurjcn/zvab086
Aims Postoperative cognitive dysfunction (POCD) is often experienced by cardiac surgery patients; however, it is not known if some groups of patients experience this more frequently or severely than others. The aim of this systematic review was to identify preoperative and postoperative predictors of cognitive dysfunction in adults following cardiac surgery. Methods and results Eight bibliographic databases were searched (January 2005 to March 2021) in relation to cardiac surgery and cognition. Studies including adult patients who had undergone open cardiac surgery and using a validated measurement of cognitive function were included. Full-text review for inclusion, quality assessment, and data extraction were undertaken independently by two authors. A total of 2870 papers were identified, of which 36 papers met the inclusion criteria and were included in the review. The majority were prospective observational studies [n = 28 (75.7%)]. In total, 61 independent predictors (45 preoperative and 16 postoperative) were identified as significant in at least one study; advancing age and education level appear important. Age has emerged as the most common predictor of cognitive outcome. Conclusion Although a number of predictors of POCD have been identified, they have inconsistently been reported as significantly affecting cognitive outcome. Consistent with previous research, our findings indicate that older patients and those with lower educational levels should be prioritized when developing and trialling interventions to improve cognitive function. These findings are less than surprising if we consider the methodological shortcomings of included studies. It is evident that further high-quality research exploring predictors of POCD is required. Registration This review was registered on Prospero, CRD42020167037
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1093/eurjcn/zvab086
- https://academic.oup.com/eurjcn/article-pdf/21/3/192/43349243/zvab086.pdf
- OA Status
- bronze
- Cited By
- 25
- References
- 62
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3203778085
All OpenAlex metadata
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https://openalex.org/W3203778085Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/eurjcn/zvab086Digital Object Identifier
- Title
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Predictors of cognitive dysfunction after cardiac surgery: a systematic reviewWork title
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
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2021-09-08Full publication date if available
- Authors
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Tracey Bowden, Catherine S. Hurt, Julie Sanders, Leanne M. AitkenList of authors in order
- Landing page
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https://doi.org/10.1093/eurjcn/zvab086Publisher landing page
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https://academic.oup.com/eurjcn/article-pdf/21/3/192/43349243/zvab086.pdfDirect link to full text PDF
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YesWhether a free full text is available
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bronzeOpen access status per OpenAlex
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https://academic.oup.com/eurjcn/article-pdf/21/3/192/43349243/zvab086.pdfDirect OA link when available
- Concepts
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Medicine, Cognition, Postoperative cognitive dysfunction, Cardiac surgery, Intensive care medicine, Internal medicine, Cardiology, PsychiatryTop concepts (fields/topics) attached by OpenAlex
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25Total citation count in OpenAlex
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2025: 8, 2024: 5, 2023: 10, 2022: 2Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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