Pretreatment circulating MAIT cells, neutrophils, and periostin predicted the real-world response after 1-year mepolizumab treatment in asthmatics Article Swipe
Hitoshi Sasano
,
Norihiro Harada
,
Sonoko Harada
,
Tomohito Takeshige
,
Yuuki Sandhu
,
Yuki Tanabe
,
Ayako Ishimori
,
Kei Matsuno
,
Tetsutaro Nagaoka
,
Jun Ito
,
Asako Chiba
,
Hisaya Akiba
,
Ryo Atsuta
,
Kenji Izuhara
,
Sachiko Miyake
,
Kazuhisa Takahashi
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1016/j.alit.2023.06.001
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1016/j.alit.2023.06.001
This study shows that circulating CD69-positive MAIT cells, neutrophils, and serum periostin might predict the real-world response after 1-year mepolizumab treatment. Furthermore, MAIT cells potentially have a protective role against type 2 airway inflammation.
Related Topics
Concepts
Periostin
Mepolizumab
Exhaled nitric oxide
Immunology
Medicine
Asthma
Eosinophil
Innate lymphoid cell
Biomarker
CD69
Inflammation
Internal medicine
IL-2 receptor
T cell
Innate immune system
Immune system
Systemic inflammation
Biology
Biochemistry
Cell biology
Extracellular matrix
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.alit.2023.06.001
- OA Status
- gold
- Cited By
- 11
- References
- 64
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4381095042
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4381095042Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1016/j.alit.2023.06.001Digital Object Identifier
- Title
-
Pretreatment circulating MAIT cells, neutrophils, and periostin predicted the real-world response after 1-year mepolizumab treatment in asthmaticsWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-06-17Full publication date if available
- Authors
-
Hitoshi Sasano, Norihiro Harada, Sonoko Harada, Tomohito Takeshige, Yuuki Sandhu, Yuki Tanabe, Ayako Ishimori, Kei Matsuno, Tetsutaro Nagaoka, Jun Ito, Asako Chiba, Hisaya Akiba, Ryo Atsuta, Kenji Izuhara, Sachiko Miyake, Kazuhisa TakahashiList of authors in order
- Landing page
-
https://doi.org/10.1016/j.alit.2023.06.001Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.1016/j.alit.2023.06.001Direct OA link when available
- Concepts
-
Periostin, Mepolizumab, Exhaled nitric oxide, Immunology, Medicine, Asthma, Eosinophil, Innate lymphoid cell, Biomarker, CD69, Inflammation, Internal medicine, IL-2 receptor, T cell, Innate immune system, Immune system, Systemic inflammation, Biology, Biochemistry, Cell biology, Extracellular matrixTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
11Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 6, 2024: 4, 2023: 1Per-year citation counts (last 5 years)
- References (count)
-
64Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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| corresponding_institution_ids | https://openalex.org/I34077901 |
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