Prevalence and incidence of Parkinson’s disease and other forms of parkinsonism in a cohort of elderly individuals in Southern Brazil: protocol for a population-based study Article Swipe
Gabriela Magalhães Pereira
,
Nayron Medeiros Soares
,
Neide Maria Bruscato
,
Emílio Hideyuki Moriguchi
,
João Senger
,
Berenice Maria Werle
,
Rosa M. M. de Almeida
,
Artur Francisco Schumacher Schuh
,
Carlos Roberto de Mello Rieder
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2021-054423
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2021-054423
Introduction Parkinsonism is one of the most common neurological disorders affecting the elderly. Several population-based studies have determined the epidemiology of parkinsonism, mainly Parkinson’s disease (PD), but there is still little evidence in the Brazilian population. This protocol study aims to assess the prevalence and incidence of cases of PD and other parkinsonian syndromes in a 5-year cohort in a population-based study in the southern region of Brazil. Methods and analysis A prospective population-based longitudinal study, with a cohort of development of cases of parkinsonism, divided into two phases: in phase I, two questionnaires to screen for parkinsonism (Tanner’s questionnaire), Rapid Eyes Movement (REM) sleep behaviour disorder (REM Sleep Behavior Disorder Single-Question Screen) and a short interview will be conducted with all elderly residents of Veranópolis (the first longevity Brazilian county located in the Rio Grande do Sul, Brazil) aged 60 or over. The positive screened cases will be examined independently by at least two movement disorder-trained physicians and prevalence will be determined. A comprehensive evaluation of prodromic symptoms, risk factors and clinical characteristics will be carried out. Subjects with subtle parkinsonism and a sample of healthy subjects will be followed for 5 years in a developmental cohort of parkinsonism cases. For crude incidence, all individuals admitted at the beginning of the study will be re-evaluated. Ethics and dissemination The study was approved by the research ethics committee of the Hospital de Clínicas de Porto Alegre (protocol n° 4.095.609). All participants provide their informed consent before evaluations. Findings from this survey will be disseminated through peer-reviewed publications and will be presented at conferences.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/bmjopen-2021-054423
- https://bmjopen.bmj.com/content/bmjopen/11/12/e054423.full.pdf
- OA Status
- gold
- Cited By
- 2
- References
- 39
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4200598170
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4200598170Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1136/bmjopen-2021-054423Digital Object Identifier
- Title
-
Prevalence and incidence of Parkinson’s disease and other forms of parkinsonism in a cohort of elderly individuals in Southern Brazil: protocol for a population-based studyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2021Year of publication
- Publication date
-
2021-12-01Full publication date if available
- Authors
-
Gabriela Magalhães Pereira, Nayron Medeiros Soares, Neide Maria Bruscato, Emílio Hideyuki Moriguchi, João Senger, Berenice Maria Werle, Rosa M. M. de Almeida, Artur Francisco Schumacher Schuh, Carlos Roberto de Mello RiederList of authors in order
- Landing page
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https://doi.org/10.1136/bmjopen-2021-054423Publisher landing page
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https://bmjopen.bmj.com/content/bmjopen/11/12/e054423.full.pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
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https://bmjopen.bmj.com/content/bmjopen/11/12/e054423.full.pdfDirect OA link when available
- Concepts
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Parkinsonism, Medicine, Cohort, Epidemiology, Incidence (geometry), Population, Cohort study, Pediatrics, Movement disorders, Parkinson's disease, Disease, Gerontology, Psychiatry, Internal medicine, Environmental health, Physics, OpticsTop concepts (fields/topics) attached by OpenAlex
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2Total citation count in OpenAlex
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2025: 1, 2024: 1Per-year citation counts (last 5 years)
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39Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.behaviour | 105 |
| abstract_inverted_index.committee | 227 |
| abstract_inverted_index.conducted | 119 |
| abstract_inverted_index.disorders | 9 |
| abstract_inverted_index.incidence | 45 |
| abstract_inverted_index.interview | 116 |
| abstract_inverted_index.longevity | 128 |
| abstract_inverted_index.presented | 260 |
| abstract_inverted_index.prodromic | 167 |
| abstract_inverted_index.residents | 123 |
| abstract_inverted_index.symptoms, | 168 |
| abstract_inverted_index.syndromes | 53 |
| abstract_inverted_index.determined | 17 |
| abstract_inverted_index.evaluation | 165 |
| abstract_inverted_index.incidence, | 203 |
| abstract_inverted_index.physicians | 157 |
| abstract_inverted_index.prevalence | 43, 159 |
| abstract_inverted_index.(Tanner’s | 98 |
| abstract_inverted_index.4.095.609). | 238 |
| abstract_inverted_index.determined. | 162 |
| abstract_inverted_index.development | 80 |
| abstract_inverted_index.individuals | 205 |
| abstract_inverted_index.population. | 35 |
| abstract_inverted_index.prospective | 72 |
| abstract_inverted_index.Introduction | 0 |
| abstract_inverted_index.Parkinsonism | 1 |
| abstract_inverted_index.Veranópolis | 125 |
| abstract_inverted_index.conferences. | 262 |
| abstract_inverted_index.disseminated | 253 |
| abstract_inverted_index.epidemiology | 19 |
| abstract_inverted_index.evaluations. | 246 |
| abstract_inverted_index.longitudinal | 74 |
| abstract_inverted_index.neurological | 8 |
| abstract_inverted_index.parkinsonian | 52 |
| abstract_inverted_index.parkinsonism | 97, 181, 199 |
| abstract_inverted_index.participants | 240 |
| abstract_inverted_index.publications | 256 |
| abstract_inverted_index.Parkinson’s | 23 |
| abstract_inverted_index.comprehensive | 164 |
| abstract_inverted_index.developmental | 196 |
| abstract_inverted_index.dissemination | 218 |
| abstract_inverted_index.independently | 150 |
| abstract_inverted_index.parkinsonism, | 21, 84 |
| abstract_inverted_index.peer-reviewed | 255 |
| abstract_inverted_index.re-evaluated. | 215 |
| abstract_inverted_index.questionnaires | 93 |
| abstract_inverted_index.Single-Question | 111 |
| abstract_inverted_index.characteristics | 173 |
| abstract_inverted_index.questionnaire), | 99 |
| abstract_inverted_index.disorder-trained | 156 |
| abstract_inverted_index.population-based | 14, 60, 73 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 90 |
| corresponding_author_ids | https://openalex.org/A5012332324 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 9 |
| corresponding_institution_ids | https://openalex.org/I130442723, https://openalex.org/I4210097146 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.8199999928474426 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.51372054 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |