Prevalence of Cerebral Visual Impairment in Developmental and Epileptic Encephalopathies: a systematic review protocol Article Swipe
Martina Giorgia Perinelli
,
Megan Abbott
,
Ganna Balagura
,
Antonella Riva
,
Elisabetta Amadori
,
Alberto Verrotti
,
Scott Demarest
,
Pasquale Striano
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-4237921/v1
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.21203/rs.3.rs-4237921/v1
Background Developmental and Epileptic Encephalopathies (DEEs) are defined by drug-resistant seizures and neurodevelopmental disorders. Over 50% of patients have a genetic cause. Studies have shown that patients with DEEs, regardless of genetic diagnosis, experience a central visual function disorder known as Cerebral (cortical) Visual Impairment (CVI). The prevalence of CVI in DEE patients is currently unknown. A quantitative synthesis of existing data on prevalence rates of this condition would aid in understanding the magnitude of the problem, outlining future research, and suggesting the need for therapeutic strategies for early identification and prevention of the disorder. Methods This systematic review and meta-analysis protocol adheres to the PRISMA-P statement and utilizes the JBI Manual for Evidence Synthesis, focusing on the prevalence of cerebral visual impairments in patients with developmental and epileptic encephalopathy. Eligibility criteria are established following the CoCoPop framework. Comprehensive database searches will include MEDLINE, EMBASE, Science Direct, Scopus, PsychINFO, Wiley, Highwire Press, and the Cochrane Library of Systematic Reviews. The risk of bias will be assessed using the JBI Critical Appraisal Checklist for Studies reporting prevalence data. Heterogeneity will be evaluated using Cochran’s Q statistic and the I2 statistic. Summary tables and narrative text will present characteristics of the included studies. Pooled prevalence estimates will be calculated using a random-effects model and presented graphically in forest plots. If heterogeneity is high, a narrative summary will be provided. The quality of evidence will be assessed using the GRADE methodology. Discussion This protocol outlines a systematic review and meta-analysis that aims to identify, collect, evaluate, and integrate epidemiological knowledge related to the prevalence of CVI in patients with DEEs. To the best of our knowledge, no other systematic review and meta-analysis has addressed this specific issue. The results will provide useful information for understanding the extent of the problem, outlining future research, and suggesting the need for early identification strategies. Systematic review registrations: This Systematic Review Protocol was registered in PROSPERO (CRD42023448910).
Related Topics
Concepts
Checklist
Systematic review
Critical appraisal
MEDLINE
Cochrane Library
Protocol (science)
Meta-analysis
Statistic
Medicine
Study heterogeneity
Visual impairment
Clinical psychology
Psychology
Psychiatry
Pathology
Cognitive psychology
Alternative medicine
Statistics
Law
Political science
Mathematics
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.21203/rs.3.rs-4237921/v1
- https://www.researchsquare.com/article/rs-4237921/latest.pdf
- OA Status
- gold
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4401101187
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4401101187Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.21203/rs.3.rs-4237921/v1Digital Object Identifier
- Title
-
Prevalence of Cerebral Visual Impairment in Developmental and Epileptic Encephalopathies: a systematic review protocolWork title
- Type
-
reviewOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-07-29Full publication date if available
- Authors
-
Martina Giorgia Perinelli, Megan Abbott, Ganna Balagura, Antonella Riva, Elisabetta Amadori, Alberto Verrotti, Scott Demarest, Pasquale StrianoList of authors in order
- Landing page
-
https://doi.org/10.21203/rs.3.rs-4237921/v1Publisher landing page
- PDF URL
-
https://www.researchsquare.com/article/rs-4237921/latest.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.researchsquare.com/article/rs-4237921/latest.pdfDirect OA link when available
- Concepts
-
Checklist, Systematic review, Critical appraisal, MEDLINE, Cochrane Library, Protocol (science), Meta-analysis, Statistic, Medicine, Study heterogeneity, Visual impairment, Clinical psychology, Psychology, Psychiatry, Pathology, Cognitive psychology, Alternative medicine, Statistics, Law, Political science, MathematicsTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
-
36Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4401101187 |
|---|---|
| doi | https://doi.org/10.21203/rs.3.rs-4237921/v1 |
| ids.doi | https://doi.org/10.21203/rs.3.rs-4237921/v1 |
| ids.openalex | https://openalex.org/W4401101187 |
| fwci | 0.0 |
| type | review |
| title | Prevalence of Cerebral Visual Impairment in Developmental and Epileptic Encephalopathies: a systematic review protocol |
| biblio.issue | |
| biblio.volume | |
| biblio.last_page | |
| biblio.first_page | |
| topics[0].id | https://openalex.org/T10094 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9837999939918518 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2738 |
| topics[0].subfield.display_name | Psychiatry and Mental health |
| topics[0].display_name | Epilepsy research and treatment |
| topics[1].id | https://openalex.org/T11438 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9707000255584717 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2741 |
| topics[1].subfield.display_name | Radiology, Nuclear Medicine and Imaging |
| topics[1].display_name | Retinal Imaging and Analysis |
| topics[2].id | https://openalex.org/T10170 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9355999827384949 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2731 |
| topics[2].subfield.display_name | Ophthalmology |
| topics[2].display_name | Retinal Diseases and Treatments |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C2779356329 |
| concepts[0].level | 2 |
| concepts[0].score | 0.6902610659599304 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q922625 |
| concepts[0].display_name | Checklist |
| concepts[1].id | https://openalex.org/C189708586 |
| concepts[1].level | 3 |
| concepts[1].score | 0.6490954756736755 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q1504425 |
| concepts[1].display_name | Systematic review |
| concepts[2].id | https://openalex.org/C152541439 |
| concepts[2].level | 3 |
| concepts[2].score | 0.6467718482017517 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q5186693 |
| concepts[2].display_name | Critical appraisal |
| concepts[3].id | https://openalex.org/C2779473830 |
| concepts[3].level | 2 |
| concepts[3].score | 0.6025614142417908 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q1540899 |
| concepts[3].display_name | MEDLINE |
| concepts[4].id | https://openalex.org/C2776478404 |
| concepts[4].level | 3 |
| concepts[4].score | 0.6006965041160583 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q1105187 |
| concepts[4].display_name | Cochrane Library |
| concepts[5].id | https://openalex.org/C2780385302 |
| concepts[5].level | 3 |
| concepts[5].score | 0.5204463601112366 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q367158 |
| concepts[5].display_name | Protocol (science) |
| concepts[6].id | https://openalex.org/C95190672 |
| concepts[6].level | 2 |
| concepts[6].score | 0.5055811405181885 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q815382 |
| concepts[6].display_name | Meta-analysis |
| concepts[7].id | https://openalex.org/C89128539 |
| concepts[7].level | 2 |
| concepts[7].score | 0.4871785044670105 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q1949963 |
| concepts[7].display_name | Statistic |
| concepts[8].id | https://openalex.org/C71924100 |
| concepts[8].level | 0 |
| concepts[8].score | 0.47537532448768616 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[8].display_name | Medicine |
| concepts[9].id | https://openalex.org/C119423318 |
| concepts[9].level | 3 |
| concepts[9].score | 0.4742019474506378 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q7628405 |
| concepts[9].display_name | Study heterogeneity |
| concepts[10].id | https://openalex.org/C2781372952 |
| concepts[10].level | 2 |
| concepts[10].score | 0.4275131821632385 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q737460 |
| concepts[10].display_name | Visual impairment |
| concepts[11].id | https://openalex.org/C70410870 |
| concepts[11].level | 1 |
| concepts[11].score | 0.3683100938796997 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q199906 |
| concepts[11].display_name | Clinical psychology |
| concepts[12].id | https://openalex.org/C15744967 |
| concepts[12].level | 0 |
| concepts[12].score | 0.36616623401641846 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q9418 |
| concepts[12].display_name | Psychology |
| concepts[13].id | https://openalex.org/C118552586 |
| concepts[13].level | 1 |
| concepts[13].score | 0.3498491644859314 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q7867 |
| concepts[13].display_name | Psychiatry |
| concepts[14].id | https://openalex.org/C142724271 |
| concepts[14].level | 1 |
| concepts[14].score | 0.16116172075271606 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q7208 |
| concepts[14].display_name | Pathology |
| concepts[15].id | https://openalex.org/C180747234 |
| concepts[15].level | 1 |
| concepts[15].score | 0.14236116409301758 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q23373 |
| concepts[15].display_name | Cognitive psychology |
| concepts[16].id | https://openalex.org/C204787440 |
| concepts[16].level | 2 |
| concepts[16].score | 0.12371575832366943 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q188504 |
| concepts[16].display_name | Alternative medicine |
| concepts[17].id | https://openalex.org/C105795698 |
| concepts[17].level | 1 |
| concepts[17].score | 0.0871700644493103 |
| concepts[17].wikidata | https://www.wikidata.org/wiki/Q12483 |
| concepts[17].display_name | Statistics |
| concepts[18].id | https://openalex.org/C199539241 |
| concepts[18].level | 1 |
| concepts[18].score | 0.0 |
| concepts[18].wikidata | https://www.wikidata.org/wiki/Q7748 |
| concepts[18].display_name | Law |
| concepts[19].id | https://openalex.org/C17744445 |
| concepts[19].level | 0 |
| concepts[19].score | 0.0 |
| concepts[19].wikidata | https://www.wikidata.org/wiki/Q36442 |
| concepts[19].display_name | Political science |
| concepts[20].id | https://openalex.org/C33923547 |
| concepts[20].level | 0 |
| concepts[20].score | 0.0 |
| concepts[20].wikidata | https://www.wikidata.org/wiki/Q395 |
| concepts[20].display_name | Mathematics |
| keywords[0].id | https://openalex.org/keywords/checklist |
| keywords[0].score | 0.6902610659599304 |
| keywords[0].display_name | Checklist |
| keywords[1].id | https://openalex.org/keywords/systematic-review |
| keywords[1].score | 0.6490954756736755 |
| keywords[1].display_name | Systematic review |
| keywords[2].id | https://openalex.org/keywords/critical-appraisal |
| keywords[2].score | 0.6467718482017517 |
| keywords[2].display_name | Critical appraisal |
| keywords[3].id | https://openalex.org/keywords/medline |
| keywords[3].score | 0.6025614142417908 |
| keywords[3].display_name | MEDLINE |
| keywords[4].id | https://openalex.org/keywords/cochrane-library |
| keywords[4].score | 0.6006965041160583 |
| keywords[4].display_name | Cochrane Library |
| keywords[5].id | https://openalex.org/keywords/protocol |
| keywords[5].score | 0.5204463601112366 |
| keywords[5].display_name | Protocol (science) |
| keywords[6].id | https://openalex.org/keywords/meta-analysis |
| keywords[6].score | 0.5055811405181885 |
| keywords[6].display_name | Meta-analysis |
| keywords[7].id | https://openalex.org/keywords/statistic |
| keywords[7].score | 0.4871785044670105 |
| keywords[7].display_name | Statistic |
| keywords[8].id | https://openalex.org/keywords/medicine |
| keywords[8].score | 0.47537532448768616 |
| keywords[8].display_name | Medicine |
| keywords[9].id | https://openalex.org/keywords/study-heterogeneity |
| keywords[9].score | 0.4742019474506378 |
| keywords[9].display_name | Study heterogeneity |
| keywords[10].id | https://openalex.org/keywords/visual-impairment |
| keywords[10].score | 0.4275131821632385 |
| keywords[10].display_name | Visual impairment |
| keywords[11].id | https://openalex.org/keywords/clinical-psychology |
| keywords[11].score | 0.3683100938796997 |
| keywords[11].display_name | Clinical psychology |
| keywords[12].id | https://openalex.org/keywords/psychology |
| keywords[12].score | 0.36616623401641846 |
| keywords[12].display_name | Psychology |
| keywords[13].id | https://openalex.org/keywords/psychiatry |
| keywords[13].score | 0.3498491644859314 |
| keywords[13].display_name | Psychiatry |
| keywords[14].id | https://openalex.org/keywords/pathology |
| keywords[14].score | 0.16116172075271606 |
| keywords[14].display_name | Pathology |
| keywords[15].id | https://openalex.org/keywords/cognitive-psychology |
| keywords[15].score | 0.14236116409301758 |
| keywords[15].display_name | Cognitive psychology |
| keywords[16].id | https://openalex.org/keywords/alternative-medicine |
| keywords[16].score | 0.12371575832366943 |
| keywords[16].display_name | Alternative medicine |
| keywords[17].id | https://openalex.org/keywords/statistics |
| keywords[17].score | 0.0871700644493103 |
| keywords[17].display_name | Statistics |
| language | en |
| locations[0].id | doi:10.21203/rs.3.rs-4237921/v1 |
| locations[0].is_oa | True |
| locations[0].source | |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.researchsquare.com/article/rs-4237921/latest.pdf |
| locations[0].version | acceptedVersion |
| locations[0].raw_type | posted-content |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | False |
| locations[0].raw_source_name | |
| locations[0].landing_page_url | https://doi.org/10.21203/rs.3.rs-4237921/v1 |
| indexed_in | crossref |
| authorships[0].author.id | https://openalex.org/A5072915122 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-7621-7183 |
| authorships[0].author.display_name | Martina Giorgia Perinelli |
| authorships[0].countries | IT, US |
| authorships[0].affiliations[0].raw_affiliation_string | IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini Alberto Verrotti University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina Scott Demarest Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I285663978 |
| authorships[0].affiliations[1].raw_affiliation_string | .org/0000-0002-6065-1476 |
| authorships[0].affiliations[2].institution_ids | https://openalex.org/I2801463291 |
| authorships[0].affiliations[2].raw_affiliation_string | IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini |
| authorships[0].affiliations[3].institution_ids | https://openalex.org/I4210096275, https://openalex.org/I921990950 |
| authorships[0].affiliations[3].raw_affiliation_string | University of Genoa: Universita degli Studi di Genova Megan Abbott Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience |
| authorships[0].institutions[0].id | https://openalex.org/I2801463291 |
| authorships[0].institutions[0].ror | https://ror.org/0424g0k78 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I2801463291, https://openalex.org/I4210153126 |
| authorships[0].institutions[0].country_code | IT |
| authorships[0].institutions[0].display_name | Istituto Giannina Gaslini |
| authorships[0].institutions[1].id | https://openalex.org/I4210096275 |
| authorships[0].institutions[1].ror | https://ror.org/00mj9k629 |
| authorships[0].institutions[1].type | healthcare |
| authorships[0].institutions[1].lineage | https://openalex.org/I4210096275 |
| authorships[0].institutions[1].country_code | US |
| authorships[0].institutions[1].display_name | Children's Hospital Colorado |
| authorships[0].institutions[2].id | https://openalex.org/I921990950 |
| authorships[0].institutions[2].ror | https://ror.org/02hh7en24 |
| authorships[0].institutions[2].type | education |
| authorships[0].institutions[2].lineage | https://openalex.org/I921990950 |
| authorships[0].institutions[2].country_code | US |
| authorships[0].institutions[2].display_name | University of Colorado Denver |
| authorships[0].institutions[3].id | https://openalex.org/I285663978 |
| authorships[0].institutions[3].ror | https://ror.org/02xwsbr93 |
| authorships[0].institutions[3].type | education |
| authorships[0].institutions[3].lineage | https://openalex.org/I285663978 |
| authorships[0].institutions[3].country_code | US |
| authorships[0].institutions[3].display_name | Weatherford College |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Martina Giorgia Perinelli |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | .org/0000-0002-6065-1476, IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini, IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini Alberto Verrotti University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina Scott Demarest Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute, University of Genoa: Universita degli Studi di Genova Megan Abbott Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience |
| authorships[1].author.id | https://openalex.org/A5101469184 |
| authorships[1].author.orcid | https://orcid.org/0009-0007-8692-0770 |
| authorships[1].author.display_name | Megan Abbott |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I4210096275, https://openalex.org/I921990950 |
| authorships[1].affiliations[0].raw_affiliation_string | Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[1].institutions[0].id | https://openalex.org/I4210096275 |
| authorships[1].institutions[0].ror | https://ror.org/00mj9k629 |
| authorships[1].institutions[0].type | healthcare |
| authorships[1].institutions[0].lineage | https://openalex.org/I4210096275 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Children's Hospital Colorado |
| authorships[1].institutions[1].id | https://openalex.org/I921990950 |
| authorships[1].institutions[1].ror | https://ror.org/02hh7en24 |
| authorships[1].institutions[1].type | education |
| authorships[1].institutions[1].lineage | https://openalex.org/I921990950 |
| authorships[1].institutions[1].country_code | US |
| authorships[1].institutions[1].display_name | University of Colorado Denver |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Megan Abbott |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[2].author.id | https://openalex.org/A5002614095 |
| authorships[2].author.orcid | https://orcid.org/0000-0003-0212-8318 |
| authorships[2].author.display_name | Ganna Balagura |
| authorships[2].countries | IT |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I83816512 |
| authorships[2].affiliations[0].raw_affiliation_string | Università degli Studi di Genova: Universita degli Studi di Genova |
| authorships[2].institutions[0].id | https://openalex.org/I83816512 |
| authorships[2].institutions[0].ror | https://ror.org/0107c5v14 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I83816512 |
| authorships[2].institutions[0].country_code | IT |
| authorships[2].institutions[0].display_name | University of Genoa |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Ganna Balagura |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Università degli Studi di Genova: Universita degli Studi di Genova |
| authorships[3].author.id | https://openalex.org/A5050764295 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-9152-5571 |
| authorships[3].author.display_name | Antonella Riva |
| authorships[3].countries | IT |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I83816512 |
| authorships[3].affiliations[0].raw_affiliation_string | Università degli Studi di Genova: Universita degli Studi di Genova |
| authorships[3].institutions[0].id | https://openalex.org/I83816512 |
| authorships[3].institutions[0].ror | https://ror.org/0107c5v14 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I83816512 |
| authorships[3].institutions[0].country_code | IT |
| authorships[3].institutions[0].display_name | University of Genoa |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Antonella Riva |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Università degli Studi di Genova: Universita degli Studi di Genova |
| authorships[4].author.id | https://openalex.org/A5020745215 |
| authorships[4].author.orcid | https://orcid.org/0000-0003-0935-7404 |
| authorships[4].author.display_name | Elisabetta Amadori |
| authorships[4].countries | IT, US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I4210096275, https://openalex.org/I921990950 |
| authorships[4].affiliations[0].raw_affiliation_string | University of Genoa: Universita degli Studi di Genova Megan Abbott Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I2801463291 |
| authorships[4].affiliations[1].raw_affiliation_string | IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini |
| authorships[4].affiliations[2].raw_affiliation_string | IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini Alberto Verrotti University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina Scott Demarest Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[4].affiliations[3].institution_ids | https://openalex.org/I285663978 |
| authorships[4].affiliations[3].raw_affiliation_string | .org/0000-0002-6065-1476 |
| authorships[4].institutions[0].id | https://openalex.org/I2801463291 |
| authorships[4].institutions[0].ror | https://ror.org/0424g0k78 |
| authorships[4].institutions[0].type | healthcare |
| authorships[4].institutions[0].lineage | https://openalex.org/I2801463291, https://openalex.org/I4210153126 |
| authorships[4].institutions[0].country_code | IT |
| authorships[4].institutions[0].display_name | Istituto Giannina Gaslini |
| authorships[4].institutions[1].id | https://openalex.org/I4210096275 |
| authorships[4].institutions[1].ror | https://ror.org/00mj9k629 |
| authorships[4].institutions[1].type | healthcare |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210096275 |
| authorships[4].institutions[1].country_code | US |
| authorships[4].institutions[1].display_name | Children's Hospital Colorado |
| authorships[4].institutions[2].id | https://openalex.org/I921990950 |
| authorships[4].institutions[2].ror | https://ror.org/02hh7en24 |
| authorships[4].institutions[2].type | education |
| authorships[4].institutions[2].lineage | https://openalex.org/I921990950 |
| authorships[4].institutions[2].country_code | US |
| authorships[4].institutions[2].display_name | University of Colorado Denver |
| authorships[4].institutions[3].id | https://openalex.org/I285663978 |
| authorships[4].institutions[3].ror | https://ror.org/02xwsbr93 |
| authorships[4].institutions[3].type | education |
| authorships[4].institutions[3].lineage | https://openalex.org/I285663978 |
| authorships[4].institutions[3].country_code | US |
| authorships[4].institutions[3].display_name | Weatherford College |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Elisabetta Amadori |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | .org/0000-0002-6065-1476, IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini, IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini Alberto Verrotti University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina Scott Demarest Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute, University of Genoa: Universita degli Studi di Genova Megan Abbott Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience |
| authorships[5].author.id | https://openalex.org/A5113310451 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Alberto Verrotti |
| authorships[5].countries | IT |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I27483092 |
| authorships[5].affiliations[0].raw_affiliation_string | University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina |
| authorships[5].institutions[0].id | https://openalex.org/I27483092 |
| authorships[5].institutions[0].ror | https://ror.org/00x27da85 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I27483092 |
| authorships[5].institutions[0].country_code | IT |
| authorships[5].institutions[0].display_name | University of Perugia |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Alberto Verrotti |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina |
| authorships[6].author.id | https://openalex.org/A5067016209 |
| authorships[6].author.orcid | https://orcid.org/0000-0002-4544-3724 |
| authorships[6].author.display_name | Scott Demarest |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I4210096275, https://openalex.org/I921990950 |
| authorships[6].affiliations[0].raw_affiliation_string | Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[6].institutions[0].id | https://openalex.org/I4210096275 |
| authorships[6].institutions[0].ror | https://ror.org/00mj9k629 |
| authorships[6].institutions[0].type | healthcare |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210096275 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | Children's Hospital Colorado |
| authorships[6].institutions[1].id | https://openalex.org/I921990950 |
| authorships[6].institutions[1].ror | https://ror.org/02hh7en24 |
| authorships[6].institutions[1].type | education |
| authorships[6].institutions[1].lineage | https://openalex.org/I921990950 |
| authorships[6].institutions[1].country_code | US |
| authorships[6].institutions[1].display_name | University of Colorado Denver |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Scott Demarest |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[7].author.id | https://openalex.org/A5088309302 |
| authorships[7].author.orcid | |
| authorships[7].author.display_name | Pasquale Striano |
| authorships[7].countries | IT, US |
| authorships[7].affiliations[0].raw_affiliation_string | IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini Alberto Verrotti University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina Scott Demarest Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute |
| authorships[7].affiliations[1].institution_ids | https://openalex.org/I4210096275, https://openalex.org/I921990950 |
| authorships[7].affiliations[1].raw_affiliation_string | University of Genoa: Universita degli Studi di Genova Megan Abbott Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience |
| authorships[7].affiliations[2].institution_ids | https://openalex.org/I2801463291 |
| authorships[7].affiliations[2].raw_affiliation_string | IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini |
| authorships[7].affiliations[3].institution_ids | https://openalex.org/I285663978 |
| authorships[7].affiliations[3].raw_affiliation_string | .org/0000-0002-6065-1476 |
| authorships[7].institutions[0].id | https://openalex.org/I2801463291 |
| authorships[7].institutions[0].ror | https://ror.org/0424g0k78 |
| authorships[7].institutions[0].type | healthcare |
| authorships[7].institutions[0].lineage | https://openalex.org/I2801463291, https://openalex.org/I4210153126 |
| authorships[7].institutions[0].country_code | IT |
| authorships[7].institutions[0].display_name | Istituto Giannina Gaslini |
| authorships[7].institutions[1].id | https://openalex.org/I4210096275 |
| authorships[7].institutions[1].ror | https://ror.org/00mj9k629 |
| authorships[7].institutions[1].type | healthcare |
| authorships[7].institutions[1].lineage | https://openalex.org/I4210096275 |
| authorships[7].institutions[1].country_code | US |
| authorships[7].institutions[1].display_name | Children's Hospital Colorado |
| authorships[7].institutions[2].id | https://openalex.org/I921990950 |
| authorships[7].institutions[2].ror | https://ror.org/02hh7en24 |
| authorships[7].institutions[2].type | education |
| authorships[7].institutions[2].lineage | https://openalex.org/I921990950 |
| authorships[7].institutions[2].country_code | US |
| authorships[7].institutions[2].display_name | University of Colorado Denver |
| authorships[7].institutions[3].id | https://openalex.org/I285663978 |
| authorships[7].institutions[3].ror | https://ror.org/02xwsbr93 |
| authorships[7].institutions[3].type | education |
| authorships[7].institutions[3].lineage | https://openalex.org/I285663978 |
| authorships[7].institutions[3].country_code | US |
| authorships[7].institutions[3].display_name | Weatherford College |
| authorships[7].author_position | last |
| authorships[7].raw_author_name | Pasquale Striano |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | .org/0000-0002-6065-1476, IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini, IRCCS Istituto Giannina Gaslini: Istituto Giannina Gaslini Alberto Verrotti University of Perugia Faculty of Medicine and Surgery: Universita degli Studi di Perugia Dipartimento di Medicina Scott Demarest Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience Institute, University of Genoa: Universita degli Studi di Genova Megan Abbott Children's Hospital Department of Neurology: Children's Hospital Colorado Pediatric Neuroscience |
| has_content.pdf | True |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.researchsquare.com/article/rs-4237921/latest.pdf |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Prevalence of Cerebral Visual Impairment in Developmental and Epileptic Encephalopathies: a systematic review protocol |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10094 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9837999939918518 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2738 |
| primary_topic.subfield.display_name | Psychiatry and Mental health |
| primary_topic.display_name | Epilepsy research and treatment |
| related_works | https://openalex.org/W115921393, https://openalex.org/W1985608330, https://openalex.org/W2942682264, https://openalex.org/W374461855, https://openalex.org/W4253161191, https://openalex.org/W1596653299, https://openalex.org/W2359776416, https://openalex.org/W2375153091, https://openalex.org/W2387779728, https://openalex.org/W4386190142 |
| cited_by_count | 0 |
| locations_count | 1 |
| best_oa_location.id | doi:10.21203/rs.3.rs-4237921/v1 |
| best_oa_location.is_oa | True |
| best_oa_location.source | |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.researchsquare.com/article/rs-4237921/latest.pdf |
| best_oa_location.version | acceptedVersion |
| best_oa_location.raw_type | posted-content |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | False |
| best_oa_location.raw_source_name | |
| best_oa_location.landing_page_url | https://doi.org/10.21203/rs.3.rs-4237921/v1 |
| primary_location.id | doi:10.21203/rs.3.rs-4237921/v1 |
| primary_location.is_oa | True |
| primary_location.source | |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.researchsquare.com/article/rs-4237921/latest.pdf |
| primary_location.version | acceptedVersion |
| primary_location.raw_type | posted-content |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | False |
| primary_location.raw_source_name | |
| primary_location.landing_page_url | https://doi.org/10.21203/rs.3.rs-4237921/v1 |
| publication_date | 2024-07-29 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W4225383465, https://openalex.org/W1967526806, https://openalex.org/W2041060472, https://openalex.org/W2958456424, https://openalex.org/W3199145020, https://openalex.org/W3165590853, https://openalex.org/W4210788278, https://openalex.org/W4289755212, https://openalex.org/W2916172020, https://openalex.org/W2081395445, https://openalex.org/W2051627253, https://openalex.org/W2118653361, https://openalex.org/W2149377521, https://openalex.org/W1997714962, https://openalex.org/W3130236979, https://openalex.org/W6796872752, https://openalex.org/W2888876174, https://openalex.org/W2604355298, https://openalex.org/W2617578303, https://openalex.org/W1969745014, https://openalex.org/W2080099923, https://openalex.org/W1979469164, https://openalex.org/W1999628548, https://openalex.org/W2161374186, https://openalex.org/W1979423827, https://openalex.org/W3118615836, https://openalex.org/W2417616718, https://openalex.org/W4210542220, https://openalex.org/W2021593215, https://openalex.org/W6634211006, https://openalex.org/W2981167946, https://openalex.org/W2157823046, https://openalex.org/W2165010366, https://openalex.org/W3020176834, https://openalex.org/W2104675861, https://openalex.org/W2010149513 |
| referenced_works_count | 36 |
| abstract_inverted_index.A | 57 |
| abstract_inverted_index.Q | 184 |
| abstract_inverted_index.a | 20, 35, 209, 222, 243 |
| abstract_inverted_index.I2 | 188 |
| abstract_inverted_index.If | 218 |
| abstract_inverted_index.To | 268 |
| abstract_inverted_index.as | 41 |
| abstract_inverted_index.be | 165, 180, 206, 226, 233 |
| abstract_inverted_index.by | 9 |
| abstract_inverted_index.in | 51, 71, 124, 215, 264, 318 |
| abstract_inverted_index.is | 54, 220 |
| abstract_inverted_index.no | 274 |
| abstract_inverted_index.of | 17, 31, 49, 60, 66, 75, 93, 120, 157, 162, 198, 230, 262, 271, 295 |
| abstract_inverted_index.on | 63, 117 |
| abstract_inverted_index.to | 104, 250, 259 |
| abstract_inverted_index.50% | 16 |
| abstract_inverted_index.CVI | 50, 263 |
| abstract_inverted_index.DEE | 52 |
| abstract_inverted_index.JBI | 111, 169 |
| abstract_inverted_index.The | 47, 160, 228, 285 |
| abstract_inverted_index.aid | 70 |
| abstract_inverted_index.and | 3, 12, 81, 91, 100, 108, 128, 153, 186, 192, 212, 246, 254, 278, 301 |
| abstract_inverted_index.are | 7, 133 |
| abstract_inverted_index.for | 85, 88, 113, 173, 291, 305 |
| abstract_inverted_index.has | 280 |
| abstract_inverted_index.our | 272 |
| abstract_inverted_index.the | 73, 76, 83, 94, 105, 110, 118, 136, 154, 168, 187, 199, 236, 260, 269, 293, 296, 303 |
| abstract_inverted_index.was | 316 |
| abstract_inverted_index.Over | 15 |
| abstract_inverted_index.This | 97, 240, 312 |
| abstract_inverted_index.aims | 249 |
| abstract_inverted_index.best | 270 |
| abstract_inverted_index.bias | 163 |
| abstract_inverted_index.data | 62 |
| abstract_inverted_index.have | 19, 24 |
| abstract_inverted_index.need | 84, 304 |
| abstract_inverted_index.risk | 161 |
| abstract_inverted_index.text | 194 |
| abstract_inverted_index.that | 26, 248 |
| abstract_inverted_index.this | 67, 282 |
| abstract_inverted_index.will | 142, 164, 179, 195, 205, 225, 232, 287 |
| abstract_inverted_index.with | 28, 126, 266 |
| abstract_inverted_index.DEEs, | 29 |
| abstract_inverted_index.DEEs. | 267 |
| abstract_inverted_index.GRADE | 237 |
| abstract_inverted_index.data. | 177 |
| abstract_inverted_index.early | 89, 306 |
| abstract_inverted_index.high, | 221 |
| abstract_inverted_index.known | 40 |
| abstract_inverted_index.model | 211 |
| abstract_inverted_index.other | 275 |
| abstract_inverted_index.rates | 65 |
| abstract_inverted_index.shown | 25 |
| abstract_inverted_index.using | 167, 182, 208, 235 |
| abstract_inverted_index.would | 69 |
| abstract_inverted_index.(CVI). | 46 |
| abstract_inverted_index.(DEEs) | 6 |
| abstract_inverted_index.Manual | 112 |
| abstract_inverted_index.Pooled | 202 |
| abstract_inverted_index.Press, | 152 |
| abstract_inverted_index.Review | 314 |
| abstract_inverted_index.Visual | 44 |
| abstract_inverted_index.Wiley, | 150 |
| abstract_inverted_index.cause. | 22 |
| abstract_inverted_index.extent | 294 |
| abstract_inverted_index.forest | 216 |
| abstract_inverted_index.future | 79, 299 |
| abstract_inverted_index.issue. | 284 |
| abstract_inverted_index.plots. | 217 |
| abstract_inverted_index.review | 99, 245, 277, 310 |
| abstract_inverted_index.tables | 191 |
| abstract_inverted_index.useful | 289 |
| abstract_inverted_index.visual | 37, 122 |
| abstract_inverted_index.CoCoPop | 137 |
| abstract_inverted_index.Direct, | 147 |
| abstract_inverted_index.EMBASE, | 145 |
| abstract_inverted_index.Library | 156 |
| abstract_inverted_index.Methods | 96 |
| abstract_inverted_index.Science | 146 |
| abstract_inverted_index.Scopus, | 148 |
| abstract_inverted_index.Studies | 23, 174 |
| abstract_inverted_index.Summary | 190 |
| abstract_inverted_index.adheres | 103 |
| abstract_inverted_index.central | 36 |
| abstract_inverted_index.defined | 8 |
| abstract_inverted_index.genetic | 21, 32 |
| abstract_inverted_index.include | 143 |
| abstract_inverted_index.present | 196 |
| abstract_inverted_index.provide | 288 |
| abstract_inverted_index.quality | 229 |
| abstract_inverted_index.related | 258 |
| abstract_inverted_index.results | 286 |
| abstract_inverted_index.summary | 224 |
| abstract_inverted_index.Cerebral | 42 |
| abstract_inverted_index.Cochrane | 155 |
| abstract_inverted_index.Critical | 170 |
| abstract_inverted_index.Evidence | 114 |
| abstract_inverted_index.Highwire | 151 |
| abstract_inverted_index.MEDLINE, | 144 |
| abstract_inverted_index.PRISMA-P | 106 |
| abstract_inverted_index.PROSPERO | 319 |
| abstract_inverted_index.Protocol | 315 |
| abstract_inverted_index.Reviews. | 159 |
| abstract_inverted_index.assessed | 166, 234 |
| abstract_inverted_index.cerebral | 121 |
| abstract_inverted_index.collect, | 252 |
| abstract_inverted_index.criteria | 132 |
| abstract_inverted_index.database | 140 |
| abstract_inverted_index.disorder | 39 |
| abstract_inverted_index.evidence | 231 |
| abstract_inverted_index.existing | 61 |
| abstract_inverted_index.focusing | 116 |
| abstract_inverted_index.function | 38 |
| abstract_inverted_index.included | 200 |
| abstract_inverted_index.outlines | 242 |
| abstract_inverted_index.patients | 18, 27, 53, 125, 265 |
| abstract_inverted_index.problem, | 77, 297 |
| abstract_inverted_index.protocol | 102, 241 |
| abstract_inverted_index.searches | 141 |
| abstract_inverted_index.seizures | 11 |
| abstract_inverted_index.specific | 283 |
| abstract_inverted_index.studies. | 201 |
| abstract_inverted_index.unknown. | 56 |
| abstract_inverted_index.utilizes | 109 |
| abstract_inverted_index.Appraisal | 171 |
| abstract_inverted_index.Checklist | 172 |
| abstract_inverted_index.Epileptic | 4 |
| abstract_inverted_index.addressed | 281 |
| abstract_inverted_index.condition | 68 |
| abstract_inverted_index.currently | 55 |
| abstract_inverted_index.disorder. | 95 |
| abstract_inverted_index.epileptic | 129 |
| abstract_inverted_index.estimates | 204 |
| abstract_inverted_index.evaluate, | 253 |
| abstract_inverted_index.evaluated | 181 |
| abstract_inverted_index.following | 135 |
| abstract_inverted_index.identify, | 251 |
| abstract_inverted_index.integrate | 255 |
| abstract_inverted_index.knowledge | 257 |
| abstract_inverted_index.magnitude | 74 |
| abstract_inverted_index.narrative | 193, 223 |
| abstract_inverted_index.outlining | 78, 298 |
| abstract_inverted_index.presented | 213 |
| abstract_inverted_index.provided. | 227 |
| abstract_inverted_index.reporting | 175 |
| abstract_inverted_index.research, | 80, 300 |
| abstract_inverted_index.statement | 107 |
| abstract_inverted_index.statistic | 185 |
| abstract_inverted_index.synthesis | 59 |
| abstract_inverted_index.(cortical) | 43 |
| abstract_inverted_index.Background | 1 |
| abstract_inverted_index.Discussion | 239 |
| abstract_inverted_index.Impairment | 45 |
| abstract_inverted_index.PsychINFO, | 149 |
| abstract_inverted_index.Synthesis, | 115 |
| abstract_inverted_index.Systematic | 158, 309, 313 |
| abstract_inverted_index.calculated | 207 |
| abstract_inverted_index.diagnosis, | 33 |
| abstract_inverted_index.disorders. | 14 |
| abstract_inverted_index.experience | 34 |
| abstract_inverted_index.framework. | 138 |
| abstract_inverted_index.knowledge, | 273 |
| abstract_inverted_index.prevalence | 48, 64, 119, 176, 203, 261 |
| abstract_inverted_index.prevention | 92 |
| abstract_inverted_index.regardless | 30 |
| abstract_inverted_index.registered | 317 |
| abstract_inverted_index.statistic. | 189 |
| abstract_inverted_index.strategies | 87 |
| abstract_inverted_index.suggesting | 82, 302 |
| abstract_inverted_index.systematic | 98, 244, 276 |
| abstract_inverted_index.Cochran’s | 183 |
| abstract_inverted_index.Eligibility | 131 |
| abstract_inverted_index.established | 134 |
| abstract_inverted_index.graphically | 214 |
| abstract_inverted_index.impairments | 123 |
| abstract_inverted_index.information | 290 |
| abstract_inverted_index.strategies. | 308 |
| abstract_inverted_index.therapeutic | 86 |
| abstract_inverted_index.methodology. | 238 |
| abstract_inverted_index.quantitative | 58 |
| abstract_inverted_index.Comprehensive | 139 |
| abstract_inverted_index.Developmental | 2 |
| abstract_inverted_index.Heterogeneity | 178 |
| abstract_inverted_index.developmental | 127 |
| abstract_inverted_index.heterogeneity | 219 |
| abstract_inverted_index.meta-analysis | 101, 247, 279 |
| abstract_inverted_index.understanding | 72, 292 |
| abstract_inverted_index.drug-resistant | 10 |
| abstract_inverted_index.identification | 90, 307 |
| abstract_inverted_index.random-effects | 210 |
| abstract_inverted_index.registrations: | 311 |
| abstract_inverted_index.characteristics | 197 |
| abstract_inverted_index.encephalopathy. | 130 |
| abstract_inverted_index.epidemiological | 256 |
| abstract_inverted_index.Encephalopathies | 5 |
| abstract_inverted_index.(CRD42023448910). | 320 |
| abstract_inverted_index.neurodevelopmental | 13 |
| abstract_inverted_index.<title>Abstract</title> | 0 |
| cited_by_percentile_year | |
| countries_distinct_count | 2 |
| institutions_distinct_count | 8 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7799999713897705 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.19201459 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |