Primary Prevention of Fatal Ventricular Arrhythmias With Implantable Cardioverter- Defibrillator Therapy – An Analysis of Implications Based on MADIT II Criteria Article Swipe
Zia I. Carrim
,
Ashraf Khan
,
Shazad Aslam
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.26443/mjm.v9i1.745
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.26443/mjm.v9i1.745
Aims: The primary aim of this retrospective study was to determine the proportion of patients with myocardial infarction (MI) who fulfil the criteria of the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II and the implications of MADIT II criteria in practice. Methods: We performed a retrospective analysis of three hundred and ninety four admissions to the Coronary Care Unit (CCU) of the Royal Infirmary of Edinburgh. We selected those with myocardial infarction (MI) and attempted to retrieve electronic copies of their echocardiogram reports. When available, these were used to assess requirement for primary-prevention Implantable Cardioverter Defibrillator (ICD) therapy based on reported left ventricular function. Results: One hundred and ninety patients were admitted to the CCU with a diagnosis of MI. Of these, 100 patients (51.5%) had an echocardiogram. Requirement for ICD therapy was unlikely in 87 (87%), probable in 6 (6%) and necessary in 7 (7%). Since a significant number of patients in the probable category were also likely to meet MADIT II criteria, we concluded that the proportion of patients requiring primary-prevention ICD therapy would be no less than 7% and more likely to be 13%. Conclusion: In the context of a busy teaching hospital, a figure of 13% for the requirement of ICD therapy in MI patients represents annual implantation activity of at least 100 per million. This is likely to have very significant resource implications.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.26443/mjm.v9i1.745
- https://mjm.mcgill.ca/article/download/745/544
- OA Status
- diamond
- Cited By
- 1
- References
- 23
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W30021580
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W30021580Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.26443/mjm.v9i1.745Digital Object Identifier
- Title
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Primary Prevention of Fatal Ventricular Arrhythmias With Implantable Cardioverter- Defibrillator Therapy – An Analysis of Implications Based on MADIT II CriteriaWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-12-01Full publication date if available
- Authors
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Zia I. Carrim, Ashraf Khan, Shazad AslamList of authors in order
- Landing page
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https://doi.org/10.26443/mjm.v9i1.745Publisher landing page
- PDF URL
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https://mjm.mcgill.ca/article/download/745/544Direct link to full text PDF
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YesWhether a free full text is available
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-
diamondOpen access status per OpenAlex
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https://mjm.mcgill.ca/article/download/745/544Direct OA link when available
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Medicine, Context (archaeology), Myocardial infarction, Implantable cardioverter-defibrillator, Coronary care unit, Internal medicine, Retrospective cohort study, Cardiology, Secondary prevention, Emergency medicine, Paleontology, BiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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1Total citation count in OpenAlex
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23Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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 | 0, 1, 2, 3, 232, 233, 234 |
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 | 231 |
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