Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection Article Swipe

PDF

A. Christy Wyckoff , Nathan L. Galloway , Crystal Meyerett-Reid , Jenny G. Powers , Terry R. Spraker , Ryan J. Monello , Bruce Pulford , Margaret A. Wild , Michael F. Antolin , Kurt C. VerCauteren , Mark D. Zabel ·

YOU? · · 2015 · Open Access · · DOI: https://doi.org/10.1038/srep08358

Related Topics

Chronic Wasting Disease

Concepts

Chronic wasting disease Population Disease Gold standard (test) Prion protein Credible interval Biology Pathology Lymph node Medicine Internal medicine Confidence interval Scrapie Environmental health

Metadata

Type: article
Language: en
Landing Page: https://doi.org/10.1038/srep08358
PDF: https://www.nature.com/articles/srep08358.pdf
OA Status: gold
Cited By: 8
References: 52
Related Works: 10
OpenAlex ID: https://openalex.org/W2041703436

All OpenAlex metadata

Raw OpenAlex JSON

OpenAlex ID: https://openalex.org/W2041703436

Canonical identifier for this work in OpenAlex
DOI: https://doi.org/10.1038/srep08358

Digital Object Identifier
Title: Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection

Work title
Type: article

OpenAlex work type
Language: en

Primary language
Publication year: 2015

Year of publication
Publication date: 2015-02-10

Full publication date if available
Authors: A. Christy Wyckoff, Nathan L. Galloway, Crystal Meyerett-Reid, Jenny G. Powers, Terry R. Spraker, Ryan J. Monello, Bruce Pulford, Margaret A. Wild, Michael F. Antolin, Kurt C. VerCauteren, Mark D. Zabel

List of authors in order
Landing page: https://doi.org/10.1038/srep08358

Publisher landing page
PDF URL: https://www.nature.com/articles/srep08358.pdf

Direct link to full text PDF
Open access: Yes

Whether a free full text is available
OA status: gold

Open access status per OpenAlex
OA URL: https://www.nature.com/articles/srep08358.pdf

Direct OA link when available
Concepts: Chronic wasting disease, Population, Disease, Gold standard (test), Prion protein, Credible interval, Biology, Pathology, Lymph node, Medicine, Internal medicine, Confidence interval, Scrapie, Environmental health

Top concepts (fields/topics) attached by OpenAlex
Cited by: 8

Total citation count in OpenAlex
Citations by year (recent): 2025: 1, 2024: 1, 2018: 1, 2017: 2, 2016: 2

Per-year citation counts (last 5 years)
References (count): 52

Number of works referenced by this work
Related works (count): 10

Other works algorithmically related by OpenAlex

Full payload

id	https://openalex.org/W2041703436
doi	https://doi.org/10.1038/srep08358
ids.doi	https://doi.org/10.1038/srep08358
ids.mag	2041703436
ids.pmid	https://pubmed.ncbi.nlm.nih.gov/25665713
ids.openalex	https://openalex.org/W2041703436
fwci	0.86655855
mesh[0].qualifier_ui
mesh[0].descriptor_ui	D000818
mesh[0].is_major_topic	False
mesh[0].qualifier_name
mesh[0].descriptor_name	Animals
mesh[1].qualifier_ui
mesh[1].descriptor_ui	D001499
mesh[1].is_major_topic	False
mesh[1].qualifier_name
mesh[1].descriptor_name	Bayes Theorem
mesh[2].qualifier_ui	Q000378
mesh[2].descriptor_ui	D001921
mesh[2].is_major_topic	False
mesh[2].qualifier_name	metabolism
mesh[2].descriptor_name	Brain
mesh[3].qualifier_ui	Q000473
mesh[3].descriptor_ui	D001921
mesh[3].is_major_topic	False
mesh[3].qualifier_name	pathology
mesh[3].descriptor_name	Brain
mesh[4].qualifier_ui
mesh[4].descriptor_ui	D003670
mesh[4].is_major_topic	False
mesh[4].qualifier_name
mesh[4].descriptor_name	Deer
mesh[5].qualifier_ui
mesh[5].descriptor_ui	D051379
mesh[5].is_major_topic	False
mesh[5].qualifier_name
mesh[5].descriptor_name	Mice
mesh[6].qualifier_ui
mesh[6].descriptor_ui	D008954
mesh[6].is_major_topic	True
mesh[6].qualifier_name
mesh[6].descriptor_name	Models, Biological
mesh[7].qualifier_ui	Q000378
mesh[7].descriptor_ui	D011328
mesh[7].is_major_topic	False
mesh[7].qualifier_name	metabolism
mesh[7].descriptor_name	Prions
mesh[8].qualifier_ui	Q000175
mesh[8].descriptor_ui	D034081
mesh[8].is_major_topic	True
mesh[8].qualifier_name	diagnosis
mesh[8].descriptor_name	Wasting Disease, Chronic
mesh[9].qualifier_ui	Q000378
mesh[9].descriptor_ui	D034081
mesh[9].is_major_topic	True
mesh[9].qualifier_name	metabolism
mesh[9].descriptor_name	Wasting Disease, Chronic
mesh[10].qualifier_ui
mesh[10].descriptor_ui	D000818
mesh[10].is_major_topic	False
mesh[10].qualifier_name
mesh[10].descriptor_name	Animals
mesh[11].qualifier_ui
mesh[11].descriptor_ui	D001499
mesh[11].is_major_topic	False
mesh[11].qualifier_name
mesh[11].descriptor_name	Bayes Theorem
mesh[12].qualifier_ui	Q000378
mesh[12].descriptor_ui	D001921
mesh[12].is_major_topic	False
mesh[12].qualifier_name	metabolism
mesh[12].descriptor_name	Brain
mesh[13].qualifier_ui	Q000473
mesh[13].descriptor_ui	D001921
mesh[13].is_major_topic	False
mesh[13].qualifier_name	pathology
mesh[13].descriptor_name	Brain
mesh[14].qualifier_ui
mesh[14].descriptor_ui	D003670
mesh[14].is_major_topic	False
mesh[14].qualifier_name
mesh[14].descriptor_name	Deer
mesh[15].qualifier_ui
mesh[15].descriptor_ui	D051379
mesh[15].is_major_topic	False
mesh[15].qualifier_name
mesh[15].descriptor_name	Mice
mesh[16].qualifier_ui
mesh[16].descriptor_ui	D008954
mesh[16].is_major_topic	True
mesh[16].qualifier_name
mesh[16].descriptor_name	Models, Biological
mesh[17].qualifier_ui	Q000378
mesh[17].descriptor_ui	D011328
mesh[17].is_major_topic	False
mesh[17].qualifier_name	metabolism
mesh[17].descriptor_name	Prions
mesh[18].qualifier_ui	Q000175
mesh[18].descriptor_ui	D034081
mesh[18].is_major_topic	True
mesh[18].qualifier_name	diagnosis
mesh[18].descriptor_name	Wasting Disease, Chronic
mesh[19].qualifier_ui	Q000378
mesh[19].descriptor_ui	D034081
mesh[19].is_major_topic	True
mesh[19].qualifier_name	metabolism
mesh[19].descriptor_name	Wasting Disease, Chronic
type	article
title	Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection
biblio.issue	1
biblio.volume	5
biblio.last_page	8358
biblio.first_page	8358
topics[0].id	https://openalex.org/T11335
topics[0].field.id	https://openalex.org/fields/13
topics[0].field.display_name	Biochemistry, Genetics and Molecular Biology
topics[0].score	0.9998999834060669
topics[0].domain.id	https://openalex.org/domains/1
topics[0].domain.display_name	Life Sciences
topics[0].subfield.id	https://openalex.org/subfields/1312
topics[0].subfield.display_name	Molecular Biology
topics[0].display_name	Prion Diseases and Protein Misfolding
topics[1].id	https://openalex.org/T13481
topics[1].field.id	https://openalex.org/fields/28
topics[1].field.display_name	Neuroscience
topics[1].score	0.9624999761581421
topics[1].domain.id	https://openalex.org/domains/1
topics[1].domain.display_name	Life Sciences
topics[1].subfield.id	https://openalex.org/subfields/2808
topics[1].subfield.display_name	Neurology
topics[1].display_name	Neurological diseases and metabolism
topics[2].id	https://openalex.org/T10915
topics[2].field.id	https://openalex.org/fields/29
topics[2].field.display_name	Nursing
topics[2].score	0.9172000288963318
topics[2].domain.id	https://openalex.org/domains/4
topics[2].domain.display_name	Health Sciences
topics[2].subfield.id	https://openalex.org/subfields/2916
topics[2].subfield.display_name	Nutrition and Dietetics
topics[2].display_name	Trace Elements in Health
is_xpac	False
apc_list.value	1890
apc_list.currency	EUR
apc_list.value_usd	2190
apc_paid.value	1890
apc_paid.currency	EUR
apc_paid.value_usd	2190
concepts[0].id	https://openalex.org/C2779728475
concepts[0].level	5
concepts[0].score	0.9084206819534302
concepts[0].wikidata	https://www.wikidata.org/wiki/Q1087811
concepts[0].display_name	Chronic wasting disease
concepts[1].id	https://openalex.org/C2908647359
concepts[1].level	2
concepts[1].score	0.5698465704917908
concepts[1].wikidata	https://www.wikidata.org/wiki/Q2625603
concepts[1].display_name	Population
concepts[2].id	https://openalex.org/C2779134260
concepts[2].level	2
concepts[2].score	0.4771311283111572
concepts[2].wikidata	https://www.wikidata.org/wiki/Q12136
concepts[2].display_name	Disease
concepts[3].id	https://openalex.org/C40993552
concepts[3].level	2
concepts[3].score	0.45394283533096313
concepts[3].wikidata	https://www.wikidata.org/wiki/Q514654
concepts[3].display_name	Gold standard (test)
concepts[4].id	https://openalex.org/C3019804061
concepts[4].level	3
concepts[4].score	0.4448170065879822
concepts[4].wikidata	https://www.wikidata.org/wiki/Q14881255
concepts[4].display_name	Prion protein
concepts[5].id	https://openalex.org/C121117317
concepts[5].level	3
concepts[5].score	0.4381091892719269
concepts[5].wikidata	https://www.wikidata.org/wiki/Q4439221
concepts[5].display_name	Credible interval
concepts[6].id	https://openalex.org/C86803240
concepts[6].level	0
concepts[6].score	0.43145880103111267
concepts[6].wikidata	https://www.wikidata.org/wiki/Q420
concepts[6].display_name	Biology
concepts[7].id	https://openalex.org/C142724271
concepts[7].level	1
concepts[7].score	0.4158351719379425
concepts[7].wikidata	https://www.wikidata.org/wiki/Q7208
concepts[7].display_name	Pathology
concepts[8].id	https://openalex.org/C2780849966
concepts[8].level	2
concepts[8].score	0.4101313650608063
concepts[8].wikidata	https://www.wikidata.org/wiki/Q170758
concepts[8].display_name	Lymph node
concepts[9].id	https://openalex.org/C71924100
concepts[9].level	0
concepts[9].score	0.401577353477478
concepts[9].wikidata	https://www.wikidata.org/wiki/Q11190
concepts[9].display_name	Medicine
concepts[10].id	https://openalex.org/C126322002
concepts[10].level	1
concepts[10].score	0.3520662486553192
concepts[10].wikidata	https://www.wikidata.org/wiki/Q11180
concepts[10].display_name	Internal medicine
concepts[11].id	https://openalex.org/C44249647
concepts[11].level	2
concepts[11].score	0.3112959861755371
concepts[11].wikidata	https://www.wikidata.org/wiki/Q208498
concepts[11].display_name	Confidence interval
concepts[12].id	https://openalex.org/C2776735649
concepts[12].level	4
concepts[12].score	0.08292999863624573
concepts[12].wikidata	https://www.wikidata.org/wiki/Q170102
concepts[12].display_name	Scrapie
concepts[13].id	https://openalex.org/C99454951
concepts[13].level	1
concepts[13].score	0.0
concepts[13].wikidata	https://www.wikidata.org/wiki/Q932068
concepts[13].display_name	Environmental health
keywords[0].id	https://openalex.org/keywords/chronic-wasting-disease
keywords[0].score	0.9084206819534302
keywords[0].display_name	Chronic wasting disease
keywords[1].id	https://openalex.org/keywords/population
keywords[1].score	0.5698465704917908
keywords[1].display_name	Population
keywords[2].id	https://openalex.org/keywords/disease
keywords[2].score	0.4771311283111572
keywords[2].display_name	Disease
keywords[3].id	https://openalex.org/keywords/gold-standard
keywords[3].score	0.45394283533096313
keywords[3].display_name	Gold standard (test)
keywords[4].id	https://openalex.org/keywords/prion-protein
keywords[4].score	0.4448170065879822
keywords[4].display_name	Prion protein
keywords[5].id	https://openalex.org/keywords/credible-interval
keywords[5].score	0.4381091892719269
keywords[5].display_name	Credible interval
keywords[6].id	https://openalex.org/keywords/biology
keywords[6].score	0.43145880103111267
keywords[6].display_name	Biology
keywords[7].id	https://openalex.org/keywords/pathology
keywords[7].score	0.4158351719379425
keywords[7].display_name	Pathology
keywords[8].id	https://openalex.org/keywords/lymph-node
keywords[8].score	0.4101313650608063
keywords[8].display_name	Lymph node
keywords[9].id	https://openalex.org/keywords/medicine
keywords[9].score	0.401577353477478
keywords[9].display_name	Medicine
keywords[10].id	https://openalex.org/keywords/internal-medicine
keywords[10].score	0.3520662486553192
keywords[10].display_name	Internal medicine
keywords[11].id	https://openalex.org/keywords/confidence-interval
keywords[11].score	0.3112959861755371
keywords[11].display_name	Confidence interval
keywords[12].id	https://openalex.org/keywords/scrapie
keywords[12].score	0.08292999863624573
keywords[12].display_name	Scrapie
language	en
locations[0].id	doi:10.1038/srep08358
locations[0].is_oa	True
locations[0].source.id	https://openalex.org/S196734849
locations[0].source.issn	2045-2322
locations[0].source.type	journal
locations[0].source.is_oa	True
locations[0].source.issn_l	2045-2322
locations[0].source.is_core	True
locations[0].source.is_in_doaj	True
locations[0].source.display_name	Scientific Reports
locations[0].source.host_organization	https://openalex.org/P4310319908
locations[0].source.host_organization_name	Nature Portfolio
locations[0].source.host_organization_lineage	https://openalex.org/P4310319908, https://openalex.org/P4310319965
locations[0].source.host_organization_lineage_names	Nature Portfolio, Springer Nature
locations[0].license	cc-by
locations[0].pdf_url	https://www.nature.com/articles/srep08358.pdf
locations[0].version	publishedVersion
locations[0].raw_type	journal-article
locations[0].license_id	https://openalex.org/licenses/cc-by
locations[0].is_accepted	True
locations[0].is_published	True
locations[0].raw_source_name	Scientific Reports
locations[0].landing_page_url	https://doi.org/10.1038/srep08358
locations[1].id	pmid:25665713
locations[1].is_oa	False
locations[1].source.id	https://openalex.org/S4306525036
locations[1].source.issn
locations[1].source.type	repository
locations[1].source.is_oa	False
locations[1].source.issn_l
locations[1].source.is_core	False
locations[1].source.is_in_doaj	False
locations[1].source.display_name	PubMed
locations[1].source.host_organization	https://openalex.org/I1299303238
locations[1].source.host_organization_name	National Institutes of Health
locations[1].source.host_organization_lineage	https://openalex.org/I1299303238
locations[1].license
locations[1].pdf_url
locations[1].version	publishedVersion
locations[1].raw_type
locations[1].license_id
locations[1].is_accepted	True
locations[1].is_published	True
locations[1].raw_source_name	Scientific reports
locations[1].landing_page_url	https://pubmed.ncbi.nlm.nih.gov/25665713
locations[2].id	pmh:oai:pubmedcentral.nih.gov:5389033
locations[2].is_oa	True
locations[2].source.id	https://openalex.org/S2764455111
locations[2].source.issn
locations[2].source.type	repository
locations[2].source.is_oa	False
locations[2].source.issn_l
locations[2].source.is_core	False
locations[2].source.is_in_doaj	False
locations[2].source.display_name	PubMed Central
locations[2].source.host_organization	https://openalex.org/I1299303238
locations[2].source.host_organization_name	National Institutes of Health
locations[2].source.host_organization_lineage	https://openalex.org/I1299303238
locations[2].license	cc-by
locations[2].pdf_url
locations[2].version	submittedVersion
locations[2].raw_type	Text
locations[2].license_id	https://openalex.org/licenses/cc-by
locations[2].is_accepted	False
locations[2].is_published	False
locations[2].raw_source_name
locations[2].landing_page_url	http://doi.org/10.1038/srep08358
indexed_in	crossref, doaj, pubmed
authorships[0].author.id	https://openalex.org/A5070654142
authorships[0].author.orcid	https://orcid.org/0000-0002-1295-4640
authorships[0].author.display_name	A. Christy Wyckoff
authorships[0].countries	US
authorships[0].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[0].affiliations[0].raw_affiliation_string	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[0].affiliations[1].institution_ids	https://openalex.org/I1336096307
authorships[0].affiliations[1].raw_affiliation_string	United States Department of Agriculture, National Wildlife Research Center, Wildlife Services, Fort Collins
authorships[0].institutions[0].id	https://openalex.org/I92446798
authorships[0].institutions[0].ror	https://ror.org/03k1gpj17
authorships[0].institutions[0].type	education
authorships[0].institutions[0].lineage	https://openalex.org/I92446798
authorships[0].institutions[0].country_code	US
authorships[0].institutions[0].display_name	Colorado State University
authorships[0].institutions[1].id	https://openalex.org/I1336096307
authorships[0].institutions[1].ror	https://ror.org/01na82s61
authorships[0].institutions[1].type	government
authorships[0].institutions[1].lineage	https://openalex.org/I1336096307
authorships[0].institutions[1].country_code	US
authorships[0].institutions[1].display_name	United States Department of Agriculture
authorships[0].author_position	first
authorships[0].raw_author_name	A. Christy Wyckoff
authorships[0].is_corresponding	False
authorships[0].raw_affiliation_strings	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA, United States Department of Agriculture, National Wildlife Research Center, Wildlife Services, Fort Collins
authorships[1].author.id	https://openalex.org/A5074926997
authorships[1].author.orcid	https://orcid.org/0000-0002-0614-2988
authorships[1].author.display_name	Nathan L. Galloway
authorships[1].countries	US
authorships[1].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[1].affiliations[0].raw_affiliation_string	Department of Biology, College of Natural Sciences, Colorado State University, Fort Collins
authorships[1].institutions[0].id	https://openalex.org/I92446798
authorships[1].institutions[0].ror	https://ror.org/03k1gpj17
authorships[1].institutions[0].type	education
authorships[1].institutions[0].lineage	https://openalex.org/I92446798
authorships[1].institutions[0].country_code	US
authorships[1].institutions[0].display_name	Colorado State University
authorships[1].author_position	middle
authorships[1].raw_author_name	Nathan Galloway
authorships[1].is_corresponding	False
authorships[1].raw_affiliation_strings	Department of Biology, College of Natural Sciences, Colorado State University, Fort Collins
authorships[2].author.id	https://openalex.org/A5012808347
authorships[2].author.orcid
authorships[2].author.display_name	Crystal Meyerett-Reid
authorships[2].countries	US
authorships[2].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[2].affiliations[0].raw_affiliation_string	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[2].institutions[0].id	https://openalex.org/I92446798
authorships[2].institutions[0].ror	https://ror.org/03k1gpj17
authorships[2].institutions[0].type	education
authorships[2].institutions[0].lineage	https://openalex.org/I92446798
authorships[2].institutions[0].country_code	US
authorships[2].institutions[0].display_name	Colorado State University
authorships[2].author_position	middle
authorships[2].raw_author_name	Crystal Meyerett-Reid
authorships[2].is_corresponding	False
authorships[2].raw_affiliation_strings	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[3].author.id	https://openalex.org/A5075384319
authorships[3].author.orcid	https://orcid.org/0000-0002-6813-449X
authorships[3].author.display_name	Jenny G. Powers
authorships[3].countries	US
authorships[3].affiliations[0].institution_ids	https://openalex.org/I1304808963
authorships[3].affiliations[0].raw_affiliation_string	National Park Service, Biological Resource Management Division, Fort Collins, USA
authorships[3].institutions[0].id	https://openalex.org/I1304808963
authorships[3].institutions[0].ror	https://ror.org/044zqqy65
authorships[3].institutions[0].type	government
authorships[3].institutions[0].lineage	https://openalex.org/I1304808963, https://openalex.org/I1335927249
authorships[3].institutions[0].country_code	US
authorships[3].institutions[0].display_name	National Park Service
authorships[3].author_position	middle
authorships[3].raw_author_name	Jenny Powers
authorships[3].is_corresponding	False
authorships[3].raw_affiliation_strings	National Park Service, Biological Resource Management Division, Fort Collins, USA
authorships[4].author.id	https://openalex.org/A5030455651
authorships[4].author.orcid	https://orcid.org/0000-0002-6717-2937
authorships[4].author.display_name	Terry R. Spraker
authorships[4].countries	US
authorships[4].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[4].affiliations[0].raw_affiliation_string	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[4].institutions[0].id	https://openalex.org/I92446798
authorships[4].institutions[0].ror	https://ror.org/03k1gpj17
authorships[4].institutions[0].type	education
authorships[4].institutions[0].lineage	https://openalex.org/I92446798
authorships[4].institutions[0].country_code	US
authorships[4].institutions[0].display_name	Colorado State University
authorships[4].author_position	middle
authorships[4].raw_author_name	Terry Spraker
authorships[4].is_corresponding	False
authorships[4].raw_affiliation_strings	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[5].author.id	https://openalex.org/A5080320084
authorships[5].author.orcid
authorships[5].author.display_name	Ryan J. Monello
authorships[5].countries	US
authorships[5].affiliations[0].institution_ids	https://openalex.org/I1304808963
authorships[5].affiliations[0].raw_affiliation_string	National Park Service, Biological Resource Management Division, Fort Collins, USA
authorships[5].institutions[0].id	https://openalex.org/I1304808963
authorships[5].institutions[0].ror	https://ror.org/044zqqy65
authorships[5].institutions[0].type	government
authorships[5].institutions[0].lineage	https://openalex.org/I1304808963, https://openalex.org/I1335927249
authorships[5].institutions[0].country_code	US
authorships[5].institutions[0].display_name	National Park Service
authorships[5].author_position	middle
authorships[5].raw_author_name	Ryan J. Monello
authorships[5].is_corresponding	False
authorships[5].raw_affiliation_strings	National Park Service, Biological Resource Management Division, Fort Collins, USA
authorships[6].author.id	https://openalex.org/A5003192085
authorships[6].author.orcid
authorships[6].author.display_name	Bruce Pulford
authorships[6].countries	US
authorships[6].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[6].affiliations[0].raw_affiliation_string	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[6].institutions[0].id	https://openalex.org/I92446798
authorships[6].institutions[0].ror	https://ror.org/03k1gpj17
authorships[6].institutions[0].type	education
authorships[6].institutions[0].lineage	https://openalex.org/I92446798
authorships[6].institutions[0].country_code	US
authorships[6].institutions[0].display_name	Colorado State University
authorships[6].author_position	middle
authorships[6].raw_author_name	Bruce Pulford
authorships[6].is_corresponding	False
authorships[6].raw_affiliation_strings	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[7].author.id	https://openalex.org/A5032709832
authorships[7].author.orcid	https://orcid.org/0000-0003-3110-3515
authorships[7].author.display_name	Margaret A. Wild
authorships[7].countries	US
authorships[7].affiliations[0].institution_ids	https://openalex.org/I1304808963
authorships[7].affiliations[0].raw_affiliation_string	National Park Service, Biological Resource Management Division, Fort Collins, USA
authorships[7].institutions[0].id	https://openalex.org/I1304808963
authorships[7].institutions[0].ror	https://ror.org/044zqqy65
authorships[7].institutions[0].type	government
authorships[7].institutions[0].lineage	https://openalex.org/I1304808963, https://openalex.org/I1335927249
authorships[7].institutions[0].country_code	US
authorships[7].institutions[0].display_name	National Park Service
authorships[7].author_position	middle
authorships[7].raw_author_name	Margaret Wild
authorships[7].is_corresponding	False
authorships[7].raw_affiliation_strings	National Park Service, Biological Resource Management Division, Fort Collins, USA
authorships[8].author.id	https://openalex.org/A5108387664
authorships[8].author.orcid
authorships[8].author.display_name	Michael F. Antolin
authorships[8].countries	US
authorships[8].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[8].affiliations[0].raw_affiliation_string	Department of Biology, College of Natural Sciences, Colorado State University, Fort Collins
authorships[8].institutions[0].id	https://openalex.org/I92446798
authorships[8].institutions[0].ror	https://ror.org/03k1gpj17
authorships[8].institutions[0].type	education
authorships[8].institutions[0].lineage	https://openalex.org/I92446798
authorships[8].institutions[0].country_code	US
authorships[8].institutions[0].display_name	Colorado State University
authorships[8].author_position	middle
authorships[8].raw_author_name	Michael Antolin
authorships[8].is_corresponding	False
authorships[8].raw_affiliation_strings	Department of Biology, College of Natural Sciences, Colorado State University, Fort Collins
authorships[9].author.id	https://openalex.org/A5086302568
authorships[9].author.orcid	https://orcid.org/0000-0002-4783-493X
authorships[9].author.display_name	Kurt C. VerCauteren
authorships[9].countries	US
authorships[9].affiliations[0].institution_ids	https://openalex.org/I1336096307
authorships[9].affiliations[0].raw_affiliation_string	United States Department of Agriculture, National Wildlife Research Center, Wildlife Services, Fort Collins
authorships[9].institutions[0].id	https://openalex.org/I1336096307
authorships[9].institutions[0].ror	https://ror.org/01na82s61
authorships[9].institutions[0].type	government
authorships[9].institutions[0].lineage	https://openalex.org/I1336096307
authorships[9].institutions[0].country_code	US
authorships[9].institutions[0].display_name	United States Department of Agriculture
authorships[9].author_position	middle
authorships[9].raw_author_name	Kurt VerCauteren
authorships[9].is_corresponding	False
authorships[9].raw_affiliation_strings	United States Department of Agriculture, National Wildlife Research Center, Wildlife Services, Fort Collins
authorships[10].author.id	https://openalex.org/A5102894857
authorships[10].author.orcid	https://orcid.org/0000-0002-2666-9197
authorships[10].author.display_name	Mark D. Zabel
authorships[10].countries	US
authorships[10].affiliations[0].institution_ids	https://openalex.org/I92446798
authorships[10].affiliations[0].raw_affiliation_string	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
authorships[10].institutions[0].id	https://openalex.org/I92446798
authorships[10].institutions[0].ror	https://ror.org/03k1gpj17
authorships[10].institutions[0].type	education
authorships[10].institutions[0].lineage	https://openalex.org/I92446798
authorships[10].institutions[0].country_code	US
authorships[10].institutions[0].display_name	Colorado State University
authorships[10].author_position	last
authorships[10].raw_author_name	Mark Zabel
authorships[10].is_corresponding	False
authorships[10].raw_affiliation_strings	Colorado State University Prion Research Center, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, USA
has_content.pdf	True
has_content.grobid_xml	True
is_paratext	False
open_access.is_oa	True
open_access.oa_url	https://www.nature.com/articles/srep08358.pdf
open_access.oa_status	gold
open_access.any_repository_has_fulltext	False
created_date	2025-10-10T00:00:00
display_name	Prion Amplification and Hierarchical Bayesian Modeling Refine Detection of Prion Infection
has_fulltext	True
is_retracted	False
updated_date	2025-11-06T03:46:38.306776
primary_topic.id	https://openalex.org/T11335
primary_topic.field.id	https://openalex.org/fields/13
primary_topic.field.display_name	Biochemistry, Genetics and Molecular Biology
primary_topic.score	0.9998999834060669
primary_topic.domain.id	https://openalex.org/domains/1
primary_topic.domain.display_name	Life Sciences
primary_topic.subfield.id	https://openalex.org/subfields/1312
primary_topic.subfield.display_name	Molecular Biology
primary_topic.display_name	Prion Diseases and Protein Misfolding
related_works	https://openalex.org/W4224103197, https://openalex.org/W4386541214, https://openalex.org/W4312066126, https://openalex.org/W2115092764, https://openalex.org/W4285026280, https://openalex.org/W4317871187, https://openalex.org/W3184257628, https://openalex.org/W2993954718, https://openalex.org/W3038806533, https://openalex.org/W4239013579
cited_by_count	8
counts_by_year[0].year	2025
counts_by_year[0].cited_by_count	1
counts_by_year[1].year	2024
counts_by_year[1].cited_by_count	1
counts_by_year[2].year	2018
counts_by_year[2].cited_by_count	1
counts_by_year[3].year	2017
counts_by_year[3].cited_by_count	2
counts_by_year[4].year	2016
counts_by_year[4].cited_by_count	2
counts_by_year[5].year	2015
counts_by_year[5].cited_by_count	1
locations_count	3
best_oa_location.id	doi:10.1038/srep08358
best_oa_location.is_oa	True
best_oa_location.source.id	https://openalex.org/S196734849
best_oa_location.source.issn	2045-2322
best_oa_location.source.type	journal
best_oa_location.source.is_oa	True
best_oa_location.source.issn_l	2045-2322
best_oa_location.source.is_core	True
best_oa_location.source.is_in_doaj	True
best_oa_location.source.display_name	Scientific Reports
best_oa_location.source.host_organization	https://openalex.org/P4310319908
best_oa_location.source.host_organization_name	Nature Portfolio
best_oa_location.source.host_organization_lineage	https://openalex.org/P4310319908, https://openalex.org/P4310319965
best_oa_location.source.host_organization_lineage_names	Nature Portfolio, Springer Nature
best_oa_location.license	cc-by
best_oa_location.pdf_url	https://www.nature.com/articles/srep08358.pdf
best_oa_location.version	publishedVersion
best_oa_location.raw_type	journal-article
best_oa_location.license_id	https://openalex.org/licenses/cc-by
best_oa_location.is_accepted	True
best_oa_location.is_published	True
best_oa_location.raw_source_name	Scientific Reports
best_oa_location.landing_page_url	https://doi.org/10.1038/srep08358
primary_location.id	doi:10.1038/srep08358
primary_location.is_oa	True
primary_location.source.id	https://openalex.org/S196734849
primary_location.source.issn	2045-2322
primary_location.source.type	journal
primary_location.source.is_oa	True
primary_location.source.issn_l	2045-2322
primary_location.source.is_core	True
primary_location.source.is_in_doaj	True
primary_location.source.display_name	Scientific Reports
primary_location.source.host_organization	https://openalex.org/P4310319908
primary_location.source.host_organization_name	Nature Portfolio
primary_location.source.host_organization_lineage	https://openalex.org/P4310319908, https://openalex.org/P4310319965
primary_location.source.host_organization_lineage_names	Nature Portfolio, Springer Nature
primary_location.license	cc-by
primary_location.pdf_url	https://www.nature.com/articles/srep08358.pdf
primary_location.version	publishedVersion
primary_location.raw_type	journal-article
primary_location.license_id	https://openalex.org/licenses/cc-by
primary_location.is_accepted	True
primary_location.is_published	True
primary_location.raw_source_name	Scientific Reports
primary_location.landing_page_url	https://doi.org/10.1038/srep08358
publication_date	2015-02-10
publication_year	2015
referenced_works	https://openalex.org/W2138498069, https://openalex.org/W2076133781, https://openalex.org/W2011815408, https://openalex.org/W2070289358, https://openalex.org/W2086996663, https://openalex.org/W2069859543, https://openalex.org/W2099763646, https://openalex.org/W2126586779, https://openalex.org/W2083120573, https://openalex.org/W2133762154, https://openalex.org/W2052283764, https://openalex.org/W2123651142, https://openalex.org/W2171785626, https://openalex.org/W2010715530, https://openalex.org/W2050331074, https://openalex.org/W2117580648, https://openalex.org/W2170770427, https://openalex.org/W2155298520, https://openalex.org/W1993393898, https://openalex.org/W2115158951, https://openalex.org/W2145364729, https://openalex.org/W2014142698, https://openalex.org/W2017126556, https://openalex.org/W2070174956, https://openalex.org/W2073381196, https://openalex.org/W2156884776, https://openalex.org/W1994239210, https://openalex.org/W2124617432, https://openalex.org/W2162189420, https://openalex.org/W2138468217, https://openalex.org/W2051363082, https://openalex.org/W2161452466, https://openalex.org/W1992666783, https://openalex.org/W2121674689, https://openalex.org/W2061629007, https://openalex.org/W2143337243, https://openalex.org/W2138542466, https://openalex.org/W2324608744, https://openalex.org/W1518605921, https://openalex.org/W2029797840, https://openalex.org/W2159037445, https://openalex.org/W2081000358, https://openalex.org/W1997666701, https://openalex.org/W2146255380, https://openalex.org/W2093697965, https://openalex.org/W2148351296, https://openalex.org/W2142401333, https://openalex.org/W2112515788, https://openalex.org/W2101570135, https://openalex.org/W2047495451, https://openalex.org/W2133307731, https://openalex.org/W68436435
referenced_works_count	52
abstract_inverted_index
cited_by_percentile_year.max	96
cited_by_percentile_year.min	89
countries_distinct_count	1
institutions_distinct_count	11
sustainable_development_goals[0].id	https://metadata.un.org/sdg/15
sustainable_development_goals[0].score	0.5299999713897705
sustainable_development_goals[0].display_name	Life in Land
citation_normalized_percentile.value	0.75122061
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False