Probing the effect of the capping polyelectrolyte on the internal structure of Layer-by-Layer decorated nanoliposomes Article Swipe
Ana Mateos Maroto
,
J.E. Rubio
,
Sylvain Prévost
,
Armando Maestro
,
Ramón G. Rubio
,
Francisco Ortega
,
Eduardo Guzmán
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.5281/zenodo.7852860
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.5281/zenodo.7852860
Hypothesis The internal organization of polyelectrolyte layers deposited on colloidal templates plays a very important role for the potential applications of these systems as capsules for drug delivery purposes. Experiments The mutual arrangement of oppositely charged polyelectrolyte layers upon their deposition on positively charged liposomes has been studied by combining up three different scattering techniques and Electronic Spin Resonance, which has provided information about the inter-layer interactions and their effect on the final structure of the capsules. Findings The sequential deposition of oppositely charged polyelectrolytes on the external leaflet of positively charged liposomes allows modulating the organization of the obtained supramolecular structures, impacting the packing and rigidity of the obtained capsules due to the change of the ionic cross-linking of the multi-layered film as a result of the specific charge of the last deposited layer. The possibility to modulate the properties of the LbL capsules by tuning the characteristics of the last deposited layers offers a very interesting route for the design of materials for encapsulation purposes with their properties controlled almost at will by changing the number of deposited layers and their chemistry.
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- OA Status
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4366574541Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.5281/zenodo.7852860Digital Object Identifier
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Probing the effect of the capping polyelectrolyte on the internal structure of Layer-by-Layer decorated nanoliposomesWork title
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articleOpenAlex work type
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enPrimary language
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2023Year of publication
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2023-02-18Full publication date if available
- Authors
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Ana Mateos Maroto, J.E. Rubio, Sylvain Prévost, Armando Maestro, Ramón G. Rubio, Francisco Ortega, Eduardo GuzmánList of authors in order
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https://doi.org/10.5281/zenodo.7852860Publisher landing page
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YesWhether a free full text is available
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greenOpen access status per OpenAlex
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https://doi.org/10.5281/zenodo.7852860Direct OA link when available
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Polyelectrolyte, Layer (electronics), Layer by layer, Materials science, Chemical engineering, Chemistry, Nanotechnology, Composite material, Polymer, EngineeringTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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