Proceedings of the 13th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical Article Swipe
E.N. Balashova
,
Olivia Beaulieu
,
Imen Benhmida
,
Ala Birca
,
Geraldine B. Boylan
,
Katherine Carkeek
,
Rasheda A. Chowdhury
,
Maria Roberta Cilio
,
Anna Consoli
,
Gabriel Côté‐Corriveau
,
Deborah Cuddyer
,
Dmitriy Degtyarev
,
Mathieu Dehaes
,
Eugene Dempsey
,
A Dereymaeker
,
Béatrice Desnous
,
Mohamed El‐Dib
,
Elhaytham Elsayed
,
Henry A. Feldman
,
Daragh Finn
,
Maria Angela Franceschini
,
Shoshana Freeman
,
Marie-Michele Gagnon
,
Mélanie Gagnon
,
Aisling A. Garvey
,
Anirban Ghosh
,
Yulia Golubtsova
,
P. Ellen Grant
,
Susanne C. Hay
,
Tim H. J. Hermans
,
Emily Herzberg
,
C. Hsiao
,
Maria Iennaco
,
Terrie E. Inder
,
Oleg Ionov
,
Kutlu Kaya
,
Faith Keister
,
Miriah Kemigisha
,
Anna Kirtbaya
,
Sarah Lee
,
Lara M. Leijser
,
Steve M. Liao
,
Pei‐Yi Lin
,
Rachel Lippman
,
Vicki Livingstone
,
Thuy Mai Luu
,
Joshua Magombe
,
Zamzam Mahdi
,
Bohdana Marandyuk
,
Alyssa Martin
,
Sean Mathieson
,
Edith Mbabazi
,
Khorshid Mohammad
,
Michael Moore
,
Ronald Mulondo
,
Chelsea Munster
,
Deirdre M. Murray
,
Esther Nalule
,
Davis Natukwatsa
,
Gunnar Naulaers
,
Mona Noroozi
,
Brian Nsubuga Kaaya
,
John E. O’Toole
,
Andreea Pavel
,
Mallory Peterson
,
Elana Pinchefsky
,
Katharine Playter
,
Jennifer Queally
,
Ajay Rajaram
,
А. Yu. Ryndin
,
Steven J. Schiff
,
Marvin Seruwu
,
Diiana Sharafutdinova
,
Yvonne Sheldon
,
Marie‐Noëlle Simard
,
Jessica Sims
,
Tina Steele
,
Amélie Stritzke
,
John B. Sunwoo
,
Jason Sutin
,
Julia Tatz
,
Taylor Vadset
,
Zachary A. Vesoulis
,
Rutvi Vyas
,
Moses Wabukoma
,
Brian H. Walsh
,
Joshua Wandukwa
,
Benjamin C. Warf
,
Halana V. Whitehead
,
Michael Woglom
,
Fan-Yu Yen
,
Lucca Zampolli
,
Alexander I. Zavriyev
,
Hussein Zein
,
Bernhard Zimmermann
,
V.V. Zubkov
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3233/npm-229005
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3233/npm-229005
Hypoxic ischaemic encephalopathy (HIE), an important complication of perinatal asphyxia, remains a major health burden.Neonates are classifi ed using the Sarnat score and neonates >35 weeks with moderate/ severe HIE are treated with therapeutic hypothermia (TH).TH improves survival/ decreases disability however 30-50% of mild HIE cases (not offered TH) develop cognitive impairment.Early biomarkers are vital to redefi ne HIE and better manage these infants.Cerebral monitoring is essential to establish cerebral activity, categorise encephalopathy stages, diagnose seizures, and monitor treatment.EEG and near infrared spectroscopy (NIRS) may be used concomitantly as monitoring tools (combined cerebral activity and haemodynamics) in order to study neurovascular coupling (NVC).NVC as a biomarker may increase sensitivity and specifi city for HIE outcome prediction.Limited research exists on NVC in neonates and in HIE where lower oxygen saturation may exist, physiological patterns may be altered.Easy integration of EEG and NIRS, continuous results over long periods, different clinical settings, favors studies.NVC analysis may identify neonates at risk earlier and reduce neurodevelopmental disabilities. AIM:-Study continuous EEG and NIRS data in HIE.-Measure NVC as biomarker for asphyxia severity -Identify/establish patterns of outcome prediction -Study effects of physiological variability and medication on NVC. METHODOLOGY:-Single center retrospective cohort study -UZ Leuven, Belgium: 10-year period 2010 -2020.-Establish database and inclusions.-Inclusion: 72 hours TH, EEG and NIRS, magnetic resonance imaging (MRI) < day 10 of life.-Demographic and clinical data (REDCap system) -Statistical analysis using GraphPad Prism.-MRIs scored blinded (Weeke HIE score).Score = 0 considered normal outcome, 1-2 a mild/moderate and >2 severe HIE.Comparisons between groups were performed.
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- article
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- https://doi.org/10.3233/npm-229005
- https://content.iospress.com:443/download/journal-of-neonatal-perinatal-medicine/npm229005?id=journal-of-neonatal-perinatal-medicine%2Fnpm229005
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- References
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- OpenAlex ID
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Proceedings of the 13th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemicalWork title
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articleOpenAlex work type
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enPrimary language
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2022Year of publication
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2022-04-12Full publication date if available
- Authors
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E.N. Balashova, Olivia Beaulieu, Imen Benhmida, Ala Birca, Geraldine B. Boylan, Katherine Carkeek, Rasheda A. Chowdhury, Maria Roberta Cilio, Anna Consoli, Gabriel Côté‐Corriveau, Deborah Cuddyer, Dmitriy Degtyarev, Mathieu Dehaes, Eugene Dempsey, A Dereymaeker, Béatrice Desnous, Mohamed El‐Dib, Elhaytham Elsayed, Henry A. Feldman, Daragh Finn, Maria Angela Franceschini, Shoshana Freeman, Marie-Michele Gagnon, Mélanie Gagnon, Aisling A. Garvey, Anirban Ghosh, Yulia Golubtsova, P. Ellen Grant, Susanne C. Hay, Tim H. J. Hermans, Emily Herzberg, C. Hsiao, Maria Iennaco, Terrie E. Inder, Oleg Ionov, Kutlu Kaya, Faith Keister, Miriah Kemigisha, Anna Kirtbaya, Sarah Lee, Lara M. Leijser, Steve M. Liao, Pei‐Yi Lin, Rachel Lippman, Vicki Livingstone, Thuy Mai Luu, Joshua Magombe, Zamzam Mahdi, Bohdana Marandyuk, Alyssa Martin, Sean Mathieson, Edith Mbabazi, Khorshid Mohammad, Michael Moore, Ronald Mulondo, Chelsea Munster, Deirdre M. Murray, Esther Nalule, Davis Natukwatsa, Gunnar Naulaers, Mona Noroozi, Brian Nsubuga Kaaya, John E. O’Toole, Andreea Pavel, Mallory Peterson, Elana Pinchefsky, Katharine Playter, Jennifer Queally, Ajay Rajaram, А. Yu. Ryndin, Steven J. Schiff, Marvin Seruwu, Diiana Sharafutdinova, Yvonne Sheldon, Marie‐Noëlle Simard, Jessica Sims, Tina Steele, Amélie Stritzke, John B. Sunwoo, Jason Sutin, Julia Tatz, Taylor Vadset, Zachary A. Vesoulis, Rutvi Vyas, Moses Wabukoma, Brian H. Walsh, Joshua Wandukwa, Benjamin C. Warf, Halana V. Whitehead, Michael Woglom, Fan-Yu Yen, Lucca Zampolli, Alexander I. Zavriyev, Hussein Zein, Bernhard Zimmermann, V.V. ZubkovList of authors in order
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0Total citation count in OpenAlex
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17Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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