Journal of Neuroscience Methods • Vol 422
Profiling lamina specific pyramidal neurons using postmortem human formalin fixed paraffin embedded frontal cortex tissue in combination with digital spatial profiling
June 2025 • Aleksandra Stanisavljevic, Kyrillos W. Ibrahim, Philip Stavrides, J Christopher Bare, Melissa J. Alldred, Adriana Heguy, Ralph A. Nixon, Stephen D. G…
This optimized DSP assay provides high resolution RNA-seq data demonstrating utility and versatility of the GeoMx platform for individually characterized neurons and isolated cortical ribbons within postmortem FFPE human brain tissue for downstream analyses.