Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation Article Swipe

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Asao Noda , Shuji Mishima , Yuko Hirai , K. Hamasaki , Reid D. Landes , Hiroshi Mitani , Kei Haga , Tohru Kiyono , Nori Nakamura , Yoshiaki Kodama ·

YOU? · · 2015 · Open Access · · DOI: https://doi.org/10.1186/s41021-015-0018-4

We suggest that lamin A- or progerin-associated nuclear envelope is involved in cellular aging associated with DNA damage repair.

Related Topics

Xeroderma Pigmentosum

Molecular Biology

Dna

Concepts

Progeria Lamin DNA damage DNA repair Biology Cell biology Senescence Xeroderma pigmentosum Molecular biology DNA Genetics Gene Nucleus

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Type: article
Language: en
Landing Page: https://doi.org/10.1186/s41021-015-0018-4
PDF: https://genesenvironment.biomedcentral.com/counter/pdf/10.1186/s41021-015-0018-4
OA Status: gold
Cited By: 25
References: 57
Related Works: 10
OpenAlex ID: https://openalex.org/W2122103252

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DOI: https://doi.org/10.1186/s41021-015-0018-4

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Title: Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation

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Type: article

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Language: en

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Publication year: 2015

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Publication date: 2015-07-28

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Authors: Asao Noda, Shuji Mishima, Yuko Hirai, K. Hamasaki, Reid D. Landes, Hiroshi Mitani, Kei Haga, Tohru Kiyono, Nori Nakamura, Yoshiaki Kodama

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Landing page: https://doi.org/10.1186/s41021-015-0018-4

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PDF URL: https://genesenvironment.biomedcentral.com/counter/pdf/10.1186/s41021-015-0018-4

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Concepts: Progeria, Lamin, DNA damage, DNA repair, Biology, Cell biology, Senescence, Xeroderma pigmentosum, Molecular biology, DNA, Genetics, Gene, Nucleus

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Cited by: 25

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Citations by year (recent): 2025: 3, 2024: 1, 2023: 3, 2022: 2, 2021: 4

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References (count): 57

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Related works (count): 10

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