Prognostic significance and clinical determinants of residual dyspnoea at discharge in acute heart failure: a single-centre, prospective observational study Article Swipe
Mateusz Garus
,
Maksym Jura
,
Mateusz Guzik
,
Robert Zymliński
,
Gracjan Iwanek
,
Piotr Ponikowski
,
Jan Biegus
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2023-075302
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1136/bmjopen-2023-075302
Objective This study aimed to assess the prognostic significance of residual (discharge) dyspnoea in acute heart failure (AHF) patients. Design Single-centre, prospective observational study. Setting Patients hospitalised for decompensated AHF in a single cardiology centre, in Poland. Participants All patients (n=202) who survived the hospitalisation with the primary diagnosis of AHF and were discharged from the hospital. Primary and secondary outcome measures 1-year all-cause mortality; and the composite endpoint of 1-year all-cause mortality and rehospitalisation for the HF (whichever occurred first). Results On admission, 159 (78.7%) AHF patients presented dyspnoea at rest, while residual resting dyspnoea at discharge was present in 16 patients (7.9%). There were 48 (24%) patients with moderate/severe exertional dyspnoea at discharge. In the multivariable model, the resting dyspnoea at discharge was related to a higher risk of both 1-year mortality and composite outcome, with HR (95% CI) 8.0 (3.7 to 17.3) and 5.1 (2.6 to 10.2), respectively, both p<0.0001. Analogically, moderate or severe residual dyspnoea at discharge was related to the heightened risk of study both outcomes, with HR (95% CI) 3.1 (1.8 to 5.4) and 1.8 (1.1 to 2.9), respectively, p<0.01. Conclusions Among AHF patients the residual dyspnoea at discharge was unexpectedly common and was associated with an unfavourable outcome during 1-year follow-up.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/bmjopen-2023-075302
- https://bmjopen.bmj.com/content/bmjopen/13/11/e075302.full.pdf
- OA Status
- gold
- Cited By
- 4
- References
- 30
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4388835419
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4388835419Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/bmjopen-2023-075302Digital Object Identifier
- Title
-
Prognostic significance and clinical determinants of residual dyspnoea at discharge in acute heart failure: a single-centre, prospective observational studyWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2023Year of publication
- Publication date
-
2023-11-01Full publication date if available
- Authors
-
Mateusz Garus, Maksym Jura, Mateusz Guzik, Robert Zymliński, Gracjan Iwanek, Piotr Ponikowski, Jan BiegusList of authors in order
- Landing page
-
https://doi.org/10.1136/bmjopen-2023-075302Publisher landing page
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https://bmjopen.bmj.com/content/bmjopen/13/11/e075302.full.pdfDirect link to full text PDF
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-
YesWhether a free full text is available
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-
goldOpen access status per OpenAlex
- OA URL
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https://bmjopen.bmj.com/content/bmjopen/13/11/e075302.full.pdfDirect OA link when available
- Concepts
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Medicine, Heart failure, Observational study, Internal medicine, Cardiology, Prospective cohort study, Clinical endpoint, Hospital discharge, Clinical trialTop concepts (fields/topics) attached by OpenAlex
- Cited by
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4Total citation count in OpenAlex
- Citations by year (recent)
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2025: 3, 2024: 1Per-year citation counts (last 5 years)
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30Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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