Promising use of nanotechnology in Pythium insidiosum: a systematic review Article Swipe

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Lara Baccarin Ianiski , Aline Fontanella Maciel , Caroline Quintana Braga , Carla Weiblen , Daniela Isabel Brayer Pereira , Luís Antônio Sangioni , Jânio Morais Santúrio , Luciana Pötter , Sônia de Ávila Botton ·

YOU? · · 2022 · Open Access · · DOI: https://doi.org/10.6084/m9.figshare.21601105

The aquatic oomycete Pythium insidiosum is an emerging pathogen highly relevant in human and veterinary medicine and an etiologic agent of pythiosis, a disease of worldwide distribution mainly affecting horses, dogs, and humans, presenting cutaneous, subcutaneous, ocular, gastrointestinal, and systemic forms. The available therapeutic methods to treat this disease and its forms are not entirely effective, thus highlighting the need to investigate the forms of treatments with better efficacy, such as compounds from different pharmacological classes, compounds of natural origin, and new technological alternatives, including nanotechnology. Therefore, this study evaluated scientific publications regarding the use of nanotechnology in P. insidiosum treatment. For this, a systematic literature review, was carried out on articles published from 2010 to 2022 on the LILACS, MEDLINE, Google Scholar, PubMed, and SciELO databases using the descriptors ‘Pythium insidiosum,’ ‘pythiosis,’ ‘nanotechnology,’ ‘nanoparticles,’ ‘nanoemulsion,’ and ‘treatment.’ We reported 162 articles for the researched theme; although, only four studies were included because they met the criteria established herein. A meta-analysis was used for the statistical analysis of the data obtained in vitro studies, and we reported the use of nanotechnology can be a promising alternative in developing antimicrobial compounds with anti-P. insidiosum activity. Nevertheless, additional research is needed to verify the potential use of this technology in clinical therapy against P. insidiosum infections.

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Nanotechnology Pythium Materials science Biology Botany

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Type: review
Language: en
Landing Page: https://doi.org/10.6084/m9.figshare.21601105
OA Status: gold
Related Works: 10
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OpenAlex ID: https://openalex.org/W4394481205

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DOI: https://doi.org/10.6084/m9.figshare.21601105

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Title: Promising use of nanotechnology in Pythium insidiosum: a systematic review

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Type: review

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Language: en

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Publication year: 2022

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Publication date: 2022-01-01

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Authors: Lara Baccarin Ianiski, Aline Fontanella Maciel, Caroline Quintana Braga, Carla Weiblen, Daniela Isabel Brayer Pereira, Luís Antônio Sangioni, Jânio Morais Santúrio, Luciana Pötter, Sônia de Ávila Botton

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Landing page: https://doi.org/10.6084/m9.figshare.21601105

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OA status: gold

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OA URL: https://doi.org/10.6084/m9.figshare.21601105

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Concepts: Nanotechnology, Pythium, Materials science, Biology, Botany

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Cited by: 0

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Related works (count): 10

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