Prostate-Specific Membrane Antigen–Targeted Imaging and Its Correlation with HOXB13 Expression Article Swipe
Duminduni H. Angappulige
,
Nimrod S. Barashi
,
Nicholas Pickersgill
,
Cody Weimholt
,
Jingqin Luo
,
Ghazal Shadmani
,
Ziad Tarcha
,
Sampanna Rayamajhi
,
Nupam P. Mahajan
,
Gerald L. Andriole
,
Barry A. Siegel
,
Eric H. Kim
,
Kiran Mahajan
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.2967/jnumed.123.267301
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.2967/jnumed.123.267301
Homeobox 13 (HOXB13) is an oncogenic transcription factor that directly regulates expression of folate hydrolase 1, which encodes prostate-specific membrane antigen (PSMA). HOXB13 is expressed in primary and metastatic prostate cancers (PCs) and promotes androgen-independent PC growth. Since HOXB13 promotes resistance to androgen receptor (AR)-targeted therapies and regulates the expression of folate hydrolase 1, we investigated whether SUVs on PSMA PET would correlate with HOXB13 expression. Methods: We analyzed 2 independent PC patient cohorts who underwent PSMA PET/CT for initial staging or for biochemical recurrence. In the discovery cohort, we examined the relationship between HOXB13, PSMA, and AR messenger RNA (mRNA) expression in prostate biopsy specimens from 179 patients who underwent PSMA PET/CT with 18F-piflufolastat. In the validation cohort, we confirmed the relationship between HOXB13, PSMA, and AR by comparing protein expression in prostatectomy and lymph node (LN) sections from 19 patients enrolled in 18F-rhPSMA-7.3 PET clinical trials. Correlation and association analyses were also used to confirm the relationship between the markers, LN positivity, and PSMA PET SUVs. Results: We observed a significant correlation between PSMA and HOXB13 mRNA (P < 0.01). The association between HOXB13 and 18F-piflufolastat SUVs was also significant (SUVmax, P = 0.0005; SUVpeak, P = 0.0006). Likewise, the PSMA SUVmax was significantly associated with the expression of HOXB13 protein in the 18F-rhPSMA-7.3 PET cohort (P = 0.008). Treatment-naïve patients with LN metastases demonstrated elevated HOXB13 and PSMA levels in their tumors as well as higher PSMA tracer uptake and low AR expression. Conclusion: Our findings demonstrate that HOXB13 correlates with PSMA expression and PSMA PET SUVs at the mRNA and protein levels. Our study suggests that the PSMA PET findings may reflect oncogenic HOXB13 transcriptional activity in PC, thus potentially serving as an imaging biomarker for more aggressive disease.
Related Topics
Concepts
Glutamate carboxypeptidase II
Correlation
Prostate-specific antigen
Expression (computer science)
Antigen
Biology
Computational biology
Molecular biology
Immunology
Prostate
Computer science
Mathematics
Genetics
Cancer
Geometry
Programming language
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.2967/jnumed.123.267301
- OA Status
- hybrid
- Cited By
- 1
- References
- 46
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400080079
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4400080079Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.2967/jnumed.123.267301Digital Object Identifier
- Title
-
Prostate-Specific Membrane Antigen–Targeted Imaging and Its Correlation with HOXB13 ExpressionWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-06-27Full publication date if available
- Authors
-
Duminduni H. Angappulige, Nimrod S. Barashi, Nicholas Pickersgill, Cody Weimholt, Jingqin Luo, Ghazal Shadmani, Ziad Tarcha, Sampanna Rayamajhi, Nupam P. Mahajan, Gerald L. Andriole, Barry A. Siegel, Eric H. Kim, Kiran MahajanList of authors in order
- Landing page
-
https://doi.org/10.2967/jnumed.123.267301Publisher landing page
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://doi.org/10.2967/jnumed.123.267301Direct OA link when available
- Concepts
-
Glutamate carboxypeptidase II, Correlation, Prostate-specific antigen, Expression (computer science), Antigen, Biology, Computational biology, Molecular biology, Immunology, Prostate, Computer science, Mathematics, Genetics, Cancer, Geometry, Programming languageTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1Per-year citation counts (last 5 years)
- References (count)
-
46Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4400080079 |
|---|---|
| doi | https://doi.org/10.2967/jnumed.123.267301 |
| ids.doi | https://doi.org/10.2967/jnumed.123.267301 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/38936974 |
| ids.openalex | https://openalex.org/W4400080079 |
| fwci | 0.86262314 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D006801 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Humans |
| mesh[1].qualifier_ui | Q000378 |
| mesh[1].descriptor_ui | D018398 |
| mesh[1].is_major_topic | True |
| mesh[1].qualifier_name | metabolism |
| mesh[1].descriptor_name | Homeodomain Proteins |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D008297 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Male |
| mesh[3].qualifier_ui | Q000378 |
| mesh[3].descriptor_ui | D000954 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | metabolism |
| mesh[3].descriptor_name | Antigens, Surface |
| mesh[4].qualifier_ui | Q000378 |
| mesh[4].descriptor_ui | D043425 |
| mesh[4].is_major_topic | True |
| mesh[4].qualifier_name | metabolism |
| mesh[4].descriptor_name | Glutamate Carboxypeptidase II |
| mesh[5].qualifier_ui | Q000000981 |
| mesh[5].descriptor_ui | D011471 |
| mesh[5].is_major_topic | True |
| mesh[5].qualifier_name | diagnostic imaging |
| mesh[5].descriptor_name | Prostatic Neoplasms |
| mesh[6].qualifier_ui | Q000378 |
| mesh[6].descriptor_ui | D011471 |
| mesh[6].is_major_topic | True |
| mesh[6].qualifier_name | metabolism |
| mesh[6].descriptor_name | Prostatic Neoplasms |
| mesh[7].qualifier_ui | Q000473 |
| mesh[7].descriptor_ui | D011471 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | pathology |
| mesh[7].descriptor_name | Prostatic Neoplasms |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D000072078 |
| mesh[8].is_major_topic | True |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Positron Emission Tomography Computed Tomography |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D000368 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Aged |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D015972 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Gene Expression Regulation, Neoplastic |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D008875 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Middle Aged |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D006801 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Humans |
| mesh[13].qualifier_ui | Q000378 |
| mesh[13].descriptor_ui | D018398 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | metabolism |
| mesh[13].descriptor_name | Homeodomain Proteins |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D008297 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Male |
| mesh[15].qualifier_ui | Q000378 |
| mesh[15].descriptor_ui | D000954 |
| mesh[15].is_major_topic | True |
| mesh[15].qualifier_name | metabolism |
| mesh[15].descriptor_name | Antigens, Surface |
| mesh[16].qualifier_ui | Q000378 |
| mesh[16].descriptor_ui | D043425 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | metabolism |
| mesh[16].descriptor_name | Glutamate Carboxypeptidase II |
| mesh[17].qualifier_ui | Q000000981 |
| mesh[17].descriptor_ui | D011471 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | diagnostic imaging |
| mesh[17].descriptor_name | Prostatic Neoplasms |
| mesh[18].qualifier_ui | Q000378 |
| mesh[18].descriptor_ui | D011471 |
| mesh[18].is_major_topic | True |
| mesh[18].qualifier_name | metabolism |
| mesh[18].descriptor_name | Prostatic Neoplasms |
| mesh[19].qualifier_ui | Q000473 |
| mesh[19].descriptor_ui | D011471 |
| mesh[19].is_major_topic | True |
| mesh[19].qualifier_name | pathology |
| mesh[19].descriptor_name | Prostatic Neoplasms |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D000072078 |
| mesh[20].is_major_topic | True |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Positron Emission Tomography Computed Tomography |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D000368 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Aged |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D015972 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Gene Expression Regulation, Neoplastic |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D008875 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Middle Aged |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D006801 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Humans |
| mesh[25].qualifier_ui | Q000378 |
| mesh[25].descriptor_ui | D018398 |
| mesh[25].is_major_topic | True |
| mesh[25].qualifier_name | metabolism |
| mesh[25].descriptor_name | Homeodomain Proteins |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D008297 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Male |
| mesh[27].qualifier_ui | Q000378 |
| mesh[27].descriptor_ui | D000954 |
| mesh[27].is_major_topic | True |
| mesh[27].qualifier_name | metabolism |
| mesh[27].descriptor_name | Antigens, Surface |
| mesh[28].qualifier_ui | Q000378 |
| mesh[28].descriptor_ui | D043425 |
| mesh[28].is_major_topic | True |
| mesh[28].qualifier_name | metabolism |
| mesh[28].descriptor_name | Glutamate Carboxypeptidase II |
| mesh[29].qualifier_ui | Q000000981 |
| mesh[29].descriptor_ui | D011471 |
| mesh[29].is_major_topic | True |
| mesh[29].qualifier_name | diagnostic imaging |
| mesh[29].descriptor_name | Prostatic Neoplasms |
| mesh[30].qualifier_ui | Q000378 |
| mesh[30].descriptor_ui | D011471 |
| mesh[30].is_major_topic | True |
| mesh[30].qualifier_name | metabolism |
| mesh[30].descriptor_name | Prostatic Neoplasms |
| mesh[31].qualifier_ui | Q000473 |
| mesh[31].descriptor_ui | D011471 |
| mesh[31].is_major_topic | True |
| mesh[31].qualifier_name | pathology |
| mesh[31].descriptor_name | Prostatic Neoplasms |
| mesh[32].qualifier_ui | |
| mesh[32].descriptor_ui | D000072078 |
| mesh[32].is_major_topic | True |
| mesh[32].qualifier_name | |
| mesh[32].descriptor_name | Positron Emission Tomography Computed Tomography |
| mesh[33].qualifier_ui | |
| mesh[33].descriptor_ui | D000368 |
| mesh[33].is_major_topic | False |
| mesh[33].qualifier_name | |
| mesh[33].descriptor_name | Aged |
| mesh[34].qualifier_ui | |
| mesh[34].descriptor_ui | D015972 |
| mesh[34].is_major_topic | False |
| mesh[34].qualifier_name | |
| mesh[34].descriptor_name | Gene Expression Regulation, Neoplastic |
| mesh[35].qualifier_ui | |
| mesh[35].descriptor_ui | D008875 |
| mesh[35].is_major_topic | False |
| mesh[35].qualifier_name | |
| mesh[35].descriptor_name | Middle Aged |
| mesh[36].qualifier_ui | |
| mesh[36].descriptor_ui | D006801 |
| mesh[36].is_major_topic | False |
| mesh[36].qualifier_name | |
| mesh[36].descriptor_name | Humans |
| mesh[37].qualifier_ui | Q000378 |
| mesh[37].descriptor_ui | D018398 |
| mesh[37].is_major_topic | True |
| mesh[37].qualifier_name | metabolism |
| mesh[37].descriptor_name | Homeodomain Proteins |
| mesh[38].qualifier_ui | |
| mesh[38].descriptor_ui | D008297 |
| mesh[38].is_major_topic | False |
| mesh[38].qualifier_name | |
| mesh[38].descriptor_name | Male |
| mesh[39].qualifier_ui | Q000378 |
| mesh[39].descriptor_ui | D000954 |
| mesh[39].is_major_topic | True |
| mesh[39].qualifier_name | metabolism |
| mesh[39].descriptor_name | Antigens, Surface |
| mesh[40].qualifier_ui | Q000378 |
| mesh[40].descriptor_ui | D043425 |
| mesh[40].is_major_topic | True |
| mesh[40].qualifier_name | metabolism |
| mesh[40].descriptor_name | Glutamate Carboxypeptidase II |
| mesh[41].qualifier_ui | Q000000981 |
| mesh[41].descriptor_ui | D011471 |
| mesh[41].is_major_topic | True |
| mesh[41].qualifier_name | diagnostic imaging |
| mesh[41].descriptor_name | Prostatic Neoplasms |
| mesh[42].qualifier_ui | Q000378 |
| mesh[42].descriptor_ui | D011471 |
| mesh[42].is_major_topic | True |
| mesh[42].qualifier_name | metabolism |
| mesh[42].descriptor_name | Prostatic Neoplasms |
| mesh[43].qualifier_ui | Q000473 |
| mesh[43].descriptor_ui | D011471 |
| mesh[43].is_major_topic | True |
| mesh[43].qualifier_name | pathology |
| mesh[43].descriptor_name | Prostatic Neoplasms |
| mesh[44].qualifier_ui | |
| mesh[44].descriptor_ui | D000072078 |
| mesh[44].is_major_topic | True |
| mesh[44].qualifier_name | |
| mesh[44].descriptor_name | Positron Emission Tomography Computed Tomography |
| mesh[45].qualifier_ui | |
| mesh[45].descriptor_ui | D000368 |
| mesh[45].is_major_topic | False |
| mesh[45].qualifier_name | |
| mesh[45].descriptor_name | Aged |
| mesh[46].qualifier_ui | |
| mesh[46].descriptor_ui | D015972 |
| mesh[46].is_major_topic | False |
| mesh[46].qualifier_name | |
| mesh[46].descriptor_name | Gene Expression Regulation, Neoplastic |
| mesh[47].qualifier_ui | |
| mesh[47].descriptor_ui | D008875 |
| mesh[47].is_major_topic | False |
| mesh[47].qualifier_name | |
| mesh[47].descriptor_name | Middle Aged |
| mesh[48].qualifier_ui | |
| mesh[48].descriptor_ui | D006801 |
| mesh[48].is_major_topic | False |
| mesh[48].qualifier_name | |
| mesh[48].descriptor_name | Humans |
| mesh[49].qualifier_ui | Q000378 |
| mesh[49].descriptor_ui | D018398 |
| mesh[49].is_major_topic | True |
| mesh[49].qualifier_name | metabolism |
| mesh[49].descriptor_name | Homeodomain Proteins |
| type | article |
| title | Prostate-Specific Membrane Antigen–Targeted Imaging and Its Correlation with HOXB13 Expression |
| biblio.issue | 8 |
| biblio.volume | 65 |
| biblio.last_page | 1216 |
| biblio.first_page | 1210 |
| topics[0].id | https://openalex.org/T10543 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9995999932289124 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2740 |
| topics[0].subfield.display_name | Pulmonary and Respiratory Medicine |
| topics[0].display_name | Prostate Cancer Treatment and Research |
| topics[1].id | https://openalex.org/T11395 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9947999715805054 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2741 |
| topics[1].subfield.display_name | Radiology, Nuclear Medicine and Imaging |
| topics[1].display_name | Radiopharmaceutical Chemistry and Applications |
| topics[2].id | https://openalex.org/T10831 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9921000003814697 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2723 |
| topics[2].subfield.display_name | Immunology and Allergy |
| topics[2].display_name | Cell Adhesion Molecules Research |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C20417620 |
| concepts[0].level | 4 |
| concepts[0].score | 0.565670371055603 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q4140229 |
| concepts[0].display_name | Glutamate carboxypeptidase II |
| concepts[1].id | https://openalex.org/C117220453 |
| concepts[1].level | 2 |
| concepts[1].score | 0.5352590084075928 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q5172842 |
| concepts[1].display_name | Correlation |
| concepts[2].id | https://openalex.org/C2781406297 |
| concepts[2].level | 4 |
| concepts[2].score | 0.5277740955352783 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q409450 |
| concepts[2].display_name | Prostate-specific antigen |
| concepts[3].id | https://openalex.org/C90559484 |
| concepts[3].level | 2 |
| concepts[3].score | 0.5105417966842651 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q778379 |
| concepts[3].display_name | Expression (computer science) |
| concepts[4].id | https://openalex.org/C147483822 |
| concepts[4].level | 2 |
| concepts[4].score | 0.4630596339702606 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q103537 |
| concepts[4].display_name | Antigen |
| concepts[5].id | https://openalex.org/C86803240 |
| concepts[5].level | 0 |
| concepts[5].score | 0.41794461011886597 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[5].display_name | Biology |
| concepts[6].id | https://openalex.org/C70721500 |
| concepts[6].level | 1 |
| concepts[6].score | 0.39583027362823486 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q177005 |
| concepts[6].display_name | Computational biology |
| concepts[7].id | https://openalex.org/C153911025 |
| concepts[7].level | 1 |
| concepts[7].score | 0.36348581314086914 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q7202 |
| concepts[7].display_name | Molecular biology |
| concepts[8].id | https://openalex.org/C203014093 |
| concepts[8].level | 1 |
| concepts[8].score | 0.306932657957077 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q101929 |
| concepts[8].display_name | Immunology |
| concepts[9].id | https://openalex.org/C2776235491 |
| concepts[9].level | 3 |
| concepts[9].score | 0.30291181802749634 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q9625 |
| concepts[9].display_name | Prostate |
| concepts[10].id | https://openalex.org/C41008148 |
| concepts[10].level | 0 |
| concepts[10].score | 0.23368266224861145 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q21198 |
| concepts[10].display_name | Computer science |
| concepts[11].id | https://openalex.org/C33923547 |
| concepts[11].level | 0 |
| concepts[11].score | 0.2274455428123474 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q395 |
| concepts[11].display_name | Mathematics |
| concepts[12].id | https://openalex.org/C54355233 |
| concepts[12].level | 1 |
| concepts[12].score | 0.22228261828422546 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[12].display_name | Genetics |
| concepts[13].id | https://openalex.org/C121608353 |
| concepts[13].level | 2 |
| concepts[13].score | 0.10062670707702637 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q12078 |
| concepts[13].display_name | Cancer |
| concepts[14].id | https://openalex.org/C2524010 |
| concepts[14].level | 1 |
| concepts[14].score | 0.0 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q8087 |
| concepts[14].display_name | Geometry |
| concepts[15].id | https://openalex.org/C199360897 |
| concepts[15].level | 1 |
| concepts[15].score | 0.0 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q9143 |
| concepts[15].display_name | Programming language |
| keywords[0].id | https://openalex.org/keywords/glutamate-carboxypeptidase-ii |
| keywords[0].score | 0.565670371055603 |
| keywords[0].display_name | Glutamate carboxypeptidase II |
| keywords[1].id | https://openalex.org/keywords/correlation |
| keywords[1].score | 0.5352590084075928 |
| keywords[1].display_name | Correlation |
| keywords[2].id | https://openalex.org/keywords/prostate-specific-antigen |
| keywords[2].score | 0.5277740955352783 |
| keywords[2].display_name | Prostate-specific antigen |
| keywords[3].id | https://openalex.org/keywords/expression |
| keywords[3].score | 0.5105417966842651 |
| keywords[3].display_name | Expression (computer science) |
| keywords[4].id | https://openalex.org/keywords/antigen |
| keywords[4].score | 0.4630596339702606 |
| keywords[4].display_name | Antigen |
| keywords[5].id | https://openalex.org/keywords/biology |
| keywords[5].score | 0.41794461011886597 |
| keywords[5].display_name | Biology |
| keywords[6].id | https://openalex.org/keywords/computational-biology |
| keywords[6].score | 0.39583027362823486 |
| keywords[6].display_name | Computational biology |
| keywords[7].id | https://openalex.org/keywords/molecular-biology |
| keywords[7].score | 0.36348581314086914 |
| keywords[7].display_name | Molecular biology |
| keywords[8].id | https://openalex.org/keywords/immunology |
| keywords[8].score | 0.306932657957077 |
| keywords[8].display_name | Immunology |
| keywords[9].id | https://openalex.org/keywords/prostate |
| keywords[9].score | 0.30291181802749634 |
| keywords[9].display_name | Prostate |
| keywords[10].id | https://openalex.org/keywords/computer-science |
| keywords[10].score | 0.23368266224861145 |
| keywords[10].display_name | Computer science |
| keywords[11].id | https://openalex.org/keywords/mathematics |
| keywords[11].score | 0.2274455428123474 |
| keywords[11].display_name | Mathematics |
| keywords[12].id | https://openalex.org/keywords/genetics |
| keywords[12].score | 0.22228261828422546 |
| keywords[12].display_name | Genetics |
| keywords[13].id | https://openalex.org/keywords/cancer |
| keywords[13].score | 0.10062670707702637 |
| keywords[13].display_name | Cancer |
| language | en |
| locations[0].id | doi:10.2967/jnumed.123.267301 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S4210180780 |
| locations[0].source.issn | 2159-662X |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 2159-662X |
| locations[0].source.is_core | False |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Journal of Nuclear Medicine |
| locations[0].source.host_organization | https://openalex.org/P4310315767 |
| locations[0].source.host_organization_name | Society of Nuclear Medicine and Molecular Imaging |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310315767 |
| locations[0].source.host_organization_lineage_names | Society of Nuclear Medicine and Molecular Imaging |
| locations[0].license | cc-by |
| locations[0].pdf_url | |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Journal of Nuclear Medicine |
| locations[0].landing_page_url | https://doi.org/10.2967/jnumed.123.267301 |
| locations[1].id | pmid:38936974 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Journal of nuclear medicine : official publication, Society of Nuclear Medicine |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/38936974 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:11294063 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | J Nucl Med |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/11294063 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5031025517 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-8914-2299 |
| authorships[0].author.display_name | Duminduni H. Angappulige |
| authorships[0].countries | US |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[0].affiliations[0].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[0].institutions[0].id | https://openalex.org/I204465549 |
| authorships[0].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[0].institutions[0].country_code | US |
| authorships[0].institutions[0].display_name | Washington University in St. Louis |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Duminduni Hewa Angappulige |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[1].author.id | https://openalex.org/A5103203368 |
| authorships[1].author.orcid | https://orcid.org/0000-0003-0026-544X |
| authorships[1].author.display_name | Nimrod S. Barashi |
| authorships[1].countries | US |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[1].affiliations[0].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[1].institutions[0].id | https://openalex.org/I204465549 |
| authorships[1].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[1].institutions[0].country_code | US |
| authorships[1].institutions[0].display_name | Washington University in St. Louis |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Nimrod S. Barashi |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[2].author.id | https://openalex.org/A5024382606 |
| authorships[2].author.orcid | |
| authorships[2].author.display_name | Nicholas Pickersgill |
| authorships[2].countries | US |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[2].affiliations[0].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[2].institutions[0].id | https://openalex.org/I204465549 |
| authorships[2].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[2].institutions[0].country_code | US |
| authorships[2].institutions[0].display_name | Washington University in St. Louis |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Nicholas Pickersgill |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[3].author.id | https://openalex.org/A5025854192 |
| authorships[3].author.orcid | https://orcid.org/0000-0003-2926-343X |
| authorships[3].author.display_name | Cody Weimholt |
| authorships[3].countries | US |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[3].institutions[0].id | https://openalex.org/I204465549 |
| authorships[3].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[3].institutions[0].country_code | US |
| authorships[3].institutions[0].display_name | Washington University in St. Louis |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Cody Weimholt |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[4].author.id | https://openalex.org/A5037696116 |
| authorships[4].author.orcid | https://orcid.org/0000-0003-2759-3072 |
| authorships[4].author.display_name | Jingqin Luo |
| authorships[4].countries | US |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[4].affiliations[0].raw_affiliation_string | Division of Public Health, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[4].affiliations[1].institution_ids | https://openalex.org/I204465549 |
| authorships[4].affiliations[1].raw_affiliation_string | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri |
| authorships[4].institutions[0].id | https://openalex.org/I204465549 |
| authorships[4].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[4].institutions[0].country_code | US |
| authorships[4].institutions[0].display_name | Washington University in St. Louis |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Jingqin Luo |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, Division of Public Health, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[5].author.id | https://openalex.org/A5099586663 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Ghazal Shadmani |
| authorships[5].countries | US |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I204465549, https://openalex.org/I4210102181 |
| authorships[5].affiliations[0].raw_affiliation_string | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[5].institutions[0].id | https://openalex.org/I4210102181 |
| authorships[5].institutions[0].ror | https://ror.org/01akman82 |
| authorships[5].institutions[0].type | company |
| authorships[5].institutions[0].lineage | https://openalex.org/I4210102181 |
| authorships[5].institutions[0].country_code | US |
| authorships[5].institutions[0].display_name | Mallinckrodt (United States) |
| authorships[5].institutions[1].id | https://openalex.org/I204465549 |
| authorships[5].institutions[1].ror | https://ror.org/01yc7t268 |
| authorships[5].institutions[1].type | education |
| authorships[5].institutions[1].lineage | https://openalex.org/I204465549 |
| authorships[5].institutions[1].country_code | US |
| authorships[5].institutions[1].display_name | Washington University in St. Louis |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Ghazal Shadmani |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[6].author.id | https://openalex.org/A5099586664 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Ziad Tarcha |
| authorships[6].countries | US |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I204465549, https://openalex.org/I4210102181 |
| authorships[6].affiliations[0].raw_affiliation_string | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[6].institutions[0].id | https://openalex.org/I4210102181 |
| authorships[6].institutions[0].ror | https://ror.org/01akman82 |
| authorships[6].institutions[0].type | company |
| authorships[6].institutions[0].lineage | https://openalex.org/I4210102181 |
| authorships[6].institutions[0].country_code | US |
| authorships[6].institutions[0].display_name | Mallinckrodt (United States) |
| authorships[6].institutions[1].id | https://openalex.org/I204465549 |
| authorships[6].institutions[1].ror | https://ror.org/01yc7t268 |
| authorships[6].institutions[1].type | education |
| authorships[6].institutions[1].lineage | https://openalex.org/I204465549 |
| authorships[6].institutions[1].country_code | US |
| authorships[6].institutions[1].display_name | Washington University in St. Louis |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Ziad Tarcha |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[7].author.id | https://openalex.org/A5007375525 |
| authorships[7].author.orcid | https://orcid.org/0000-0001-8383-3216 |
| authorships[7].author.display_name | Sampanna Rayamajhi |
| authorships[7].countries | US |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I204465549, https://openalex.org/I4210102181 |
| authorships[7].affiliations[0].raw_affiliation_string | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[7].institutions[0].id | https://openalex.org/I4210102181 |
| authorships[7].institutions[0].ror | https://ror.org/01akman82 |
| authorships[7].institutions[0].type | company |
| authorships[7].institutions[0].lineage | https://openalex.org/I4210102181 |
| authorships[7].institutions[0].country_code | US |
| authorships[7].institutions[0].display_name | Mallinckrodt (United States) |
| authorships[7].institutions[1].id | https://openalex.org/I204465549 |
| authorships[7].institutions[1].ror | https://ror.org/01yc7t268 |
| authorships[7].institutions[1].type | education |
| authorships[7].institutions[1].lineage | https://openalex.org/I204465549 |
| authorships[7].institutions[1].country_code | US |
| authorships[7].institutions[1].display_name | Washington University in St. Louis |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Sampanna Rayamajhi |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[8].author.id | https://openalex.org/A5087068240 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-4150-602X |
| authorships[8].author.display_name | Nupam P. Mahajan |
| authorships[8].countries | US |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[8].affiliations[0].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[8].affiliations[1].institution_ids | https://openalex.org/I204465549 |
| authorships[8].affiliations[1].raw_affiliation_string | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri |
| authorships[8].institutions[0].id | https://openalex.org/I204465549 |
| authorships[8].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[8].institutions[0].country_code | US |
| authorships[8].institutions[0].display_name | Washington University in St. Louis |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Nupam P. Mahajan |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[9].author.id | https://openalex.org/A5086081364 |
| authorships[9].author.orcid | https://orcid.org/0000-0003-4033-2352 |
| authorships[9].author.display_name | Gerald L. Andriole |
| authorships[9].countries | US |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[9].affiliations[0].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[9].institutions[0].id | https://openalex.org/I204465549 |
| authorships[9].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[9].institutions[0].country_code | US |
| authorships[9].institutions[0].display_name | Washington University in St. Louis |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Gerald L. Andriole |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[10].author.id | https://openalex.org/A5049988109 |
| authorships[10].author.orcid | https://orcid.org/0000-0001-6246-5792 |
| authorships[10].author.display_name | Barry A. Siegel |
| authorships[10].countries | US |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[10].affiliations[0].raw_affiliation_string | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri |
| authorships[10].affiliations[1].institution_ids | https://openalex.org/I204465549, https://openalex.org/I4210102181 |
| authorships[10].affiliations[1].raw_affiliation_string | Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[10].institutions[0].id | https://openalex.org/I4210102181 |
| authorships[10].institutions[0].ror | https://ror.org/01akman82 |
| authorships[10].institutions[0].type | company |
| authorships[10].institutions[0].lineage | https://openalex.org/I4210102181 |
| authorships[10].institutions[0].country_code | US |
| authorships[10].institutions[0].display_name | Mallinckrodt (United States) |
| authorships[10].institutions[1].id | https://openalex.org/I204465549 |
| authorships[10].institutions[1].ror | https://ror.org/01yc7t268 |
| authorships[10].institutions[1].type | education |
| authorships[10].institutions[1].lineage | https://openalex.org/I204465549 |
| authorships[10].institutions[1].country_code | US |
| authorships[10].institutions[1].display_name | Washington University in St. Louis |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Barry A. Siegel |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri |
| authorships[11].author.id | https://openalex.org/A5100779047 |
| authorships[11].author.orcid | https://orcid.org/0000-0002-0284-8342 |
| authorships[11].author.display_name | Eric H. Kim |
| authorships[11].countries | US |
| authorships[11].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[11].affiliations[0].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[11].affiliations[1].institution_ids | https://openalex.org/I204465549 |
| authorships[11].affiliations[1].raw_affiliation_string | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri |
| authorships[11].institutions[0].id | https://openalex.org/I204465549 |
| authorships[11].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[11].institutions[0].type | education |
| authorships[11].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[11].institutions[0].country_code | US |
| authorships[11].institutions[0].display_name | Washington University in St. Louis |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Eric H. Kim |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[12].author.id | https://openalex.org/A5082062478 |
| authorships[12].author.orcid | https://orcid.org/0000-0001-7192-396X |
| authorships[12].author.display_name | Kiran Mahajan |
| authorships[12].countries | US |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I204465549 |
| authorships[12].affiliations[0].raw_affiliation_string | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri |
| authorships[12].affiliations[1].institution_ids | https://openalex.org/I204465549 |
| authorships[12].affiliations[1].raw_affiliation_string | Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| authorships[12].institutions[0].id | https://openalex.org/I204465549 |
| authorships[12].institutions[0].ror | https://ror.org/01yc7t268 |
| authorships[12].institutions[0].type | education |
| authorships[12].institutions[0].lineage | https://openalex.org/I204465549 |
| authorships[12].institutions[0].country_code | US |
| authorships[12].institutions[0].display_name | Washington University in St. Louis |
| authorships[12].author_position | last |
| authorships[12].raw_author_name | Kiran Mahajan |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | Alvin J. Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, Division of Urologic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri |
| has_content.pdf | False |
| has_content.grobid_xml | False |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://doi.org/10.2967/jnumed.123.267301 |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Prostate-Specific Membrane Antigen–Targeted Imaging and Its Correlation with HOXB13 Expression |
| has_fulltext | False |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10543 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9995999932289124 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2740 |
| primary_topic.subfield.display_name | Pulmonary and Respiratory Medicine |
| primary_topic.display_name | Prostate Cancer Treatment and Research |
| related_works | https://openalex.org/W4396724950, https://openalex.org/W2110010918, https://openalex.org/W2983725837, https://openalex.org/W2126741950, https://openalex.org/W4255120256, https://openalex.org/W2038145494, https://openalex.org/W2031954916, https://openalex.org/W846826746, https://openalex.org/W2381163510, https://openalex.org/W4256622085 |
| cited_by_count | 1 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.2967/jnumed.123.267301 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S4210180780 |
| best_oa_location.source.issn | 2159-662X |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 2159-662X |
| best_oa_location.source.is_core | False |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Journal of Nuclear Medicine |
| best_oa_location.source.host_organization | https://openalex.org/P4310315767 |
| best_oa_location.source.host_organization_name | Society of Nuclear Medicine and Molecular Imaging |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310315767 |
| best_oa_location.source.host_organization_lineage_names | Society of Nuclear Medicine and Molecular Imaging |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Journal of Nuclear Medicine |
| best_oa_location.landing_page_url | https://doi.org/10.2967/jnumed.123.267301 |
| primary_location.id | doi:10.2967/jnumed.123.267301 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S4210180780 |
| primary_location.source.issn | 2159-662X |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 2159-662X |
| primary_location.source.is_core | False |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Journal of Nuclear Medicine |
| primary_location.source.host_organization | https://openalex.org/P4310315767 |
| primary_location.source.host_organization_name | Society of Nuclear Medicine and Molecular Imaging |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310315767 |
| primary_location.source.host_organization_lineage_names | Society of Nuclear Medicine and Molecular Imaging |
| primary_location.license | cc-by |
| primary_location.pdf_url | |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Journal of Nuclear Medicine |
| primary_location.landing_page_url | https://doi.org/10.2967/jnumed.123.267301 |
| publication_date | 2024-06-27 |
| publication_year | 2024 |
| referenced_works | https://openalex.org/W3081551422, https://openalex.org/W2626401975, https://openalex.org/W4285802185, https://openalex.org/W2471590292, https://openalex.org/W3010398944, https://openalex.org/W6810101900, https://openalex.org/W2011660334, https://openalex.org/W2016973566, https://openalex.org/W3181663023, https://openalex.org/W3139707937, https://openalex.org/W6674975460, https://openalex.org/W2585630612, https://openalex.org/W3203431570, https://openalex.org/W4390500985, https://openalex.org/W2598884790, https://openalex.org/W4389828735, https://openalex.org/W1965617754, https://openalex.org/W4223497742, https://openalex.org/W2903950335, https://openalex.org/W4385076586, https://openalex.org/W1951061860, https://openalex.org/W3043694186, https://openalex.org/W4363675761, https://openalex.org/W2889764312, https://openalex.org/W4391693581, https://openalex.org/W4387729688, https://openalex.org/W3035162230, https://openalex.org/W2492448981, https://openalex.org/W6720140876, https://openalex.org/W3133798642, https://openalex.org/W3131780647, https://openalex.org/W2101103881, https://openalex.org/W2806280499, https://openalex.org/W2807646053, https://openalex.org/W1998923122, https://openalex.org/W2906327585, https://openalex.org/W4297236697, https://openalex.org/W2522571310, https://openalex.org/W3180150817, https://openalex.org/W2972890374, https://openalex.org/W2988034537, https://openalex.org/W3180086826, https://openalex.org/W2289942644, https://openalex.org/W4392796800, https://openalex.org/W4389210100, https://openalex.org/W3176208875 |
| referenced_works_count | 46 |
| abstract_inverted_index.2 | 69 |
| abstract_inverted_index.< | 180 |
| abstract_inverted_index.= | 194, 198, 219 |
| abstract_inverted_index.a | 171 |
| abstract_inverted_index.1, | 15, 53 |
| abstract_inverted_index.13 | 1 |
| abstract_inverted_index.19 | 140 |
| abstract_inverted_index.AR | 97, 127, 244 |
| abstract_inverted_index.In | 85, 115 |
| abstract_inverted_index.LN | 162, 224 |
| abstract_inverted_index.PC | 35, 71 |
| abstract_inverted_index.We | 67, 169 |
| abstract_inverted_index.an | 4, 286 |
| abstract_inverted_index.as | 235, 237, 285 |
| abstract_inverted_index.at | 260 |
| abstract_inverted_index.by | 128 |
| abstract_inverted_index.in | 25, 102, 132, 143, 213, 232, 280 |
| abstract_inverted_index.is | 3, 23 |
| abstract_inverted_index.of | 12, 50, 210 |
| abstract_inverted_index.on | 58 |
| abstract_inverted_index.or | 81 |
| abstract_inverted_index.to | 41, 155 |
| abstract_inverted_index.we | 54, 89, 119 |
| abstract_inverted_index.179 | 107 |
| abstract_inverted_index.Our | 247, 266 |
| abstract_inverted_index.PC, | 281 |
| abstract_inverted_index.PET | 60, 145, 166, 216, 258, 272 |
| abstract_inverted_index.RNA | 99 |
| abstract_inverted_index.The | 182 |
| abstract_inverted_index.and | 27, 32, 46, 96, 126, 134, 149, 164, 176, 186, 229, 242, 256, 263 |
| abstract_inverted_index.for | 78, 82, 289 |
| abstract_inverted_index.low | 243 |
| abstract_inverted_index.may | 274 |
| abstract_inverted_index.the | 48, 86, 91, 116, 121, 157, 160, 201, 208, 214, 261, 270 |
| abstract_inverted_index.was | 189, 204 |
| abstract_inverted_index.who | 74, 109 |
| abstract_inverted_index.(LN) | 137 |
| abstract_inverted_index.PSMA | 59, 76, 111, 165, 175, 202, 230, 239, 254, 257, 271 |
| abstract_inverted_index.SUVs | 57, 188, 259 |
| abstract_inverted_index.also | 153, 190 |
| abstract_inverted_index.from | 106, 139 |
| abstract_inverted_index.mRNA | 178, 262 |
| abstract_inverted_index.more | 290 |
| abstract_inverted_index.node | 136 |
| abstract_inverted_index.that | 8, 250, 269 |
| abstract_inverted_index.thus | 282 |
| abstract_inverted_index.used | 154 |
| abstract_inverted_index.well | 236 |
| abstract_inverted_index.were | 152 |
| abstract_inverted_index.with | 63, 113, 207, 223, 253 |
| abstract_inverted_index.(PCs) | 31 |
| abstract_inverted_index.PSMA, | 95, 125 |
| abstract_inverted_index.SUVs. | 167 |
| abstract_inverted_index.Since | 37 |
| abstract_inverted_index.lymph | 135 |
| abstract_inverted_index.study | 267 |
| abstract_inverted_index.their | 233 |
| abstract_inverted_index.which | 16 |
| abstract_inverted_index.would | 61 |
| abstract_inverted_index.(mRNA) | 100 |
| abstract_inverted_index.0.01). | 181 |
| abstract_inverted_index.HOXB13 | 22, 38, 64, 177, 185, 211, 228, 251, 277 |
| abstract_inverted_index.PET/CT | 77, 112 |
| abstract_inverted_index.biopsy | 104 |
| abstract_inverted_index.cohort | 217 |
| abstract_inverted_index.factor | 7 |
| abstract_inverted_index.folate | 13, 51 |
| abstract_inverted_index.higher | 238 |
| abstract_inverted_index.levels | 231 |
| abstract_inverted_index.tracer | 240 |
| abstract_inverted_index.tumors | 234 |
| abstract_inverted_index.uptake | 241 |
| abstract_inverted_index.(PSMA). | 21 |
| abstract_inverted_index.0.0005; | 195 |
| abstract_inverted_index.0.008). | 220 |
| abstract_inverted_index.HOXB13, | 94, 124 |
| abstract_inverted_index.antigen | 20 |
| abstract_inverted_index.between | 93, 123, 159, 174, 184 |
| abstract_inverted_index.cancers | 30 |
| abstract_inverted_index.cohort, | 88, 118 |
| abstract_inverted_index.cohorts | 73 |
| abstract_inverted_index.confirm | 156 |
| abstract_inverted_index.encodes | 17 |
| abstract_inverted_index.growth. | 36 |
| abstract_inverted_index.imaging | 287 |
| abstract_inverted_index.initial | 79 |
| abstract_inverted_index.levels. | 265 |
| abstract_inverted_index.patient | 72 |
| abstract_inverted_index.primary | 26 |
| abstract_inverted_index.protein | 130, 212, 264 |
| abstract_inverted_index.reflect | 275 |
| abstract_inverted_index.serving | 284 |
| abstract_inverted_index.staging | 80 |
| abstract_inverted_index.trials. | 147 |
| abstract_inverted_index.whether | 56 |
| abstract_inverted_index.(HOXB13) | 2 |
| abstract_inverted_index.0.0006). | 199 |
| abstract_inverted_index.<i>P</i> | 193, 197 |
| abstract_inverted_index.Homeobox | 0 |
| abstract_inverted_index.activity | 279 |
| abstract_inverted_index.analyses | 151 |
| abstract_inverted_index.analyzed | 68 |
| abstract_inverted_index.androgen | 42 |
| abstract_inverted_index.clinical | 146 |
| abstract_inverted_index.directly | 9 |
| abstract_inverted_index.disease. | 292 |
| abstract_inverted_index.elevated | 227 |
| abstract_inverted_index.enrolled | 142 |
| abstract_inverted_index.examined | 90 |
| abstract_inverted_index.findings | 248, 273 |
| abstract_inverted_index.markers, | 161 |
| abstract_inverted_index.membrane | 19 |
| abstract_inverted_index.observed | 170 |
| abstract_inverted_index.patients | 108, 141, 222 |
| abstract_inverted_index.promotes | 33, 39 |
| abstract_inverted_index.prostate | 29, 103 |
| abstract_inverted_index.receptor | 43 |
| abstract_inverted_index.sections | 138 |
| abstract_inverted_index.suggests | 268 |
| abstract_inverted_index.(<i>P</i> | 179, 218 |
| abstract_inverted_index.Likewise, | 200 |
| abstract_inverted_index.biomarker | 288 |
| abstract_inverted_index.comparing | 129 |
| abstract_inverted_index.confirmed | 120 |
| abstract_inverted_index.correlate | 62 |
| abstract_inverted_index.discovery | 87 |
| abstract_inverted_index.expressed | 24 |
| abstract_inverted_index.hydrolase | 14, 52 |
| abstract_inverted_index.messenger | 98 |
| abstract_inverted_index.oncogenic | 5, 276 |
| abstract_inverted_index.regulates | 10, 47 |
| abstract_inverted_index.specimens | 105 |
| abstract_inverted_index.therapies | 45 |
| abstract_inverted_index.underwent | 75, 110 |
| abstract_inverted_index.aggressive | 291 |
| abstract_inverted_index.associated | 206 |
| abstract_inverted_index.correlates | 252 |
| abstract_inverted_index.expression | 11, 49, 101, 131, 209, 255 |
| abstract_inverted_index.metastases | 225 |
| abstract_inverted_index.metastatic | 28 |
| abstract_inverted_index.resistance | 40 |
| abstract_inverted_index.validation | 117 |
| abstract_inverted_index.Correlation | 148 |
| abstract_inverted_index.association | 150, 183 |
| abstract_inverted_index.biochemical | 83 |
| abstract_inverted_index.correlation | 173 |
| abstract_inverted_index.demonstrate | 249 |
| abstract_inverted_index.expression. | 65, 245 |
| abstract_inverted_index.independent | 70 |
| abstract_inverted_index.positivity, | 163 |
| abstract_inverted_index.potentially | 283 |
| abstract_inverted_index.recurrence. | 84 |
| abstract_inverted_index.significant | 172, 191 |
| abstract_inverted_index.demonstrated | 226 |
| abstract_inverted_index.investigated | 55 |
| abstract_inverted_index.relationship | 92, 122, 158 |
| abstract_inverted_index.(AR)-targeted | 44 |
| abstract_inverted_index.prostatectomy | 133 |
| abstract_inverted_index.significantly | 205 |
| abstract_inverted_index.transcription | 6 |
| abstract_inverted_index.<b>Methods:</b> | 66 |
| abstract_inverted_index.<b>Results:</b> | 168 |
| abstract_inverted_index.transcriptional | 278 |
| abstract_inverted_index.Treatment-naïve | 221 |
| abstract_inverted_index.SUV<sub>max</sub> | 203 |
| abstract_inverted_index.prostate-specific | 18 |
| abstract_inverted_index.<b>Conclusion:</b> | 246 |
| abstract_inverted_index.(SUV<sub>max</sub>, | 192 |
| abstract_inverted_index.SUV<sub>peak</sub>, | 196 |
| abstract_inverted_index.androgen-independent | 34 |
| abstract_inverted_index.<sup>18</sup>F-rhPSMA-7.3 | 144, 215 |
| abstract_inverted_index.<sup>18</sup>F-piflufolastat | 187 |
| abstract_inverted_index.<sup>18</sup>F-piflufolastat. | 114 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 13 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/2 |
| sustainable_development_goals[0].score | 0.5 |
| sustainable_development_goals[0].display_name | Zero hunger |
| citation_normalized_percentile.value | 0.68254537 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |