Psychogenic fever: how psychological stress affects body temperature in the clinical population Article Swipe
Psychogenic fever is a stress-related, psychosomatic disease especially seen in young women. Some patients develop extremely high core body temperature (Tc) (up to 41°C) when they are exposed to emotional events, whereas others show persistent low-grade high Tc (37-38°C) during situations of chronic stress. The mechanism for psychogenic fever is not yet fully understood. However, clinical case reports demonstrate that psychogenic fever is not attenuated by antipyretic drugs, but by psychotropic drugs that display anxiolytic and sedative properties, or by resolving patients' difficulties via natural means or psychotherapy. Animal studies have demonstrated that psychological stress increases Tc via mechanisms distinct from infectious fever (which requires proinflammatory mediators) and that the sympathetic nervous system, particularly β3-adrenoceptor-mediated non-shivering thermogenesis in brown adipose tissue, plays an important role in the development of psychological stress-induced hyperthermia. Acute psychological stress induces a transient, monophasic increase in Tc. In contrast, repeated stress induces anticipatory hyperthermia, reduces diurnal changes in Tc, or slightly increases Tc throughout the day. Chronically stressed animals also display an enhanced hyperthermic response to a novel stress, while past fearful experiences induce conditioned hyperthermia to the fear context. The high Tc that psychogenic fever patients develop may be a complex of these diverse kinds of hyperthermic responses.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1080/23328940.2015.1056907
- https://www.tandfonline.com/doi/pdf/10.1080/23328940.2015.1056907?needAccess=true
- OA Status
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- Cited By
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- References
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W2193003531Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1080/23328940.2015.1056907Digital Object Identifier
- Title
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Psychogenic fever: how psychological stress affects body temperature in the clinical populationWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
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2015Year of publication
- Publication date
-
2015-06-03Full publication date if available
- Authors
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Takakazu OkaList of authors in order
- Landing page
-
https://doi.org/10.1080/23328940.2015.1056907Publisher landing page
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https://www.tandfonline.com/doi/pdf/10.1080/23328940.2015.1056907?needAccess=trueDirect link to full text PDF
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hybridOpen access status per OpenAlex
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https://www.tandfonline.com/doi/pdf/10.1080/23328940.2015.1056907?needAccess=trueDirect OA link when available
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Psychogenic disease, Hyperthermia, Shivering, Medicine, Psychology, Anxiolytic, Population, Anxiety, Internal medicine, Anesthesia, Psychiatry, Environmental healthTop concepts (fields/topics) attached by OpenAlex
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114Total citation count in OpenAlex
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2025: 8, 2024: 18, 2023: 10, 2022: 12, 2021: 21Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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