Psychological state at the time of psychiatric genetic counseling impacts patient empowerment: A pre–post analysis Article Swipe
Rachel Gore Moses
,
Colleen Jodarski
,
Michael Setzer
,
Katie L. Lewis
,
Jia Yan
,
Sophie Byers
,
Mani Yavi
,
Elizabeth D. Ballard
,
Magdalena Walkiewicz
,
Carlos A. Zarate
,
Jehannine Austin
,
Morgan Similuk
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1002/jgc4.1949
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1002/jgc4.1949
Psychiatric genetic counseling (GC) has been associated with patient‐reported increases in empowerment (perceived control, emotional regulation, and hope). We sought to evaluate the extent to which patients' psychological state at the time of GC is related to changes in empowerment. Participants with a history of major depressive disorder and/or bipolar disorder that had been refractory to treatment underwent psychiatric GC remotely from 2022 to 2023. GC was performed by four genetic counselors and included discussion of perceived causes of illness, multifactorial inheritance, and protective factors. Empowerment, depression, and anxiety were measured immediately prior to GC via online survey by the GCOS‐16, PHQ‐9, and GAD‐7, respectively. Empowerment was re‐assessed 2 weeks later. In total, 66/161 (41.0%) invited individuals completed both the baseline and follow‐up surveys. Participants completing both surveys were 54.6% female, 84.8% white, and ranged in age from 22 to 78 years (mean = 54.8 years). Overall, a significant change in mean empowerment was not observed ( p = 0.38); however, there were moderating effects by baseline psychological state. A multiple linear regression model incorporating PHQ‐9, GAD‐7 and baseline GCOS‐16 score predicted change in empowerment with a large effect ( F = 5.49, R 2 = 0.21, p < 0.01). A higher score on the PHQ‐9 was associated with decreases in empowerment from pre to post GC. Higher scores on the GAD‐7 and lower baseline GCOS‐16 scores were associated with increases in empowerment. Further, two‐way ANOVA was conducted to assess change in empowerment between subgroups based on the level of anxiety and depression. Those with low depression and high anxiety reported significant increases in empowerment ( F = 6.64, p = 0.01). These findings suggest that psychiatric GC may be especially helpful to individuals experiencing anxiety and low baseline empowerment. Alternative approaches may be needed to best meet the needs of those experiencing significant depression.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1002/jgc4.1949
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgc4.1949
- OA Status
- hybrid
- Cited By
- 1
- References
- 23
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400570265
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4400570265Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1002/jgc4.1949Digital Object Identifier
- Title
-
Psychological state at the time of psychiatric genetic counseling impacts patient empowerment: A pre–post analysisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-07-10Full publication date if available
- Authors
-
Rachel Gore Moses, Colleen Jodarski, Michael Setzer, Katie L. Lewis, Jia Yan, Sophie Byers, Mani Yavi, Elizabeth D. Ballard, Magdalena Walkiewicz, Carlos A. Zarate, Jehannine Austin, Morgan SimilukList of authors in order
- Landing page
-
https://doi.org/10.1002/jgc4.1949Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgc4.1949Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgc4.1949Direct OA link when available
- Concepts
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Empowerment, Medicine, Anxiety, Psychiatry, Clinical psychology, Major depressive disorder, Patient Health Questionnaire, Genetic counseling, Depression (economics), Depressive symptoms, Mood, Genetics, Economics, Biology, Political science, Macroeconomics, LawTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
- References (count)
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23Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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