Pulmonary vein isolation with additional substrate ablation for atrial fibrillation results in an increased risk for the development of atypical atrial flutter Article Swipe
Inês Neves
,
S Jacinto
,
G Portugal
,
P Silva Cunha
,
Bianor Valente
,
A Lousinha
,
H Santos
,
André Monteiro
,
R Contins
,
Filipa Ferreira
,
Mário Oliveira
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/europace/euae102.187
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1093/europace/euae102.187
Introduction Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) catheter ablation. Several extra pulmonary vein (PV) ablation strategies for substrate modification (PVI plus) have been employed to AF patients. It has not been proven that this approach decreases the recurrence of AF, and it could contribute to increase the risk of developing atypical atrial flutter. Methods Patients submitted to AF catheter ablation at our centre between 2005 and 2020 were included. Using logistic regression, we did a retrospective analysis of the association between the application of PVI plus strategies (such as ablation of the cavo tricuspid isthmus (CTI), ganglion plexus, isolation of the superior vena cava (SVC), mitral isthmus ablation and atrial roof line ablation) and the development of atypical flutter later submitted to ablation. Results Five hundred and seventy-five patients were included (64% males, age 57±12 years [between 14 and 81], 68.2% with paroxysmal AF) with > 1-year follow-up. Five hundred and five (87.8%) had PVI alone. From the 575 patients, 11 (1.9%) developed an atypical flutter during the follow-up, which was later submitted to ablation. The crude ODDS of a patient submitted to a PVI plus strategy developing atypical atrial flutter are 13.92 times higher than the one of those submitted to a stand-alone PVI technique, with a p value <0.001 (95% CI 3.96 – 48.87). When adjusted for age and history of heart failure, the ODDS of a patient submitted to a PVI plus strategy developing atypical atrial flutter are 16.29 times higher than the one of those submitted to a stand-alone PVI technique, with a p value <0.001 (95% CI 3.92 – 67.65). Conclusions Additional substrate ablation for AF significantly increases the risk of developing atypical auricular flutter.Characteristics of the study populationCharacterization of PIV plus strategies
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- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/europace/euae102.187
- https://academic.oup.com/europace/article-pdf/26/Supplement_1/euae102.187/57871836/euae102.187.pdf
- OA Status
- hybrid
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4398777419
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4398777419Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/europace/euae102.187Digital Object Identifier
- Title
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Pulmonary vein isolation with additional substrate ablation for atrial fibrillation results in an increased risk for the development of atypical atrial flutterWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2024Year of publication
- Publication date
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2024-05-01Full publication date if available
- Authors
-
Inês Neves, S Jacinto, G Portugal, P Silva Cunha, Bianor Valente, A Lousinha, H Santos, André Monteiro, R Contins, Filipa Ferreira, Mário OliveiraList of authors in order
- Landing page
-
https://doi.org/10.1093/europace/euae102.187Publisher landing page
- PDF URL
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https://academic.oup.com/europace/article-pdf/26/Supplement_1/euae102.187/57871836/euae102.187.pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
- OA URL
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https://academic.oup.com/europace/article-pdf/26/Supplement_1/euae102.187/57871836/euae102.187.pdfDirect OA link when available
- Concepts
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Medicine, Atrial fibrillation, Pulmonary vein, Atrial flutter, Cardiology, Ablation, Internal medicine, Isolation (microbiology), Bioinformatics, BiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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