Pulsed‐Field Ablation for Persistent Atrial Fibrillation in EU‐PORIA Registry Article Swipe
Jun Hirokami
,
K. R. Julian Chun
,
Stefano Bordignon
,
Shota Tohoku
,
Kars Neven
,
Tobias Reichlin
,
Yuri Blaauw
,
Jim Hansen
,
Raquel Adeliño
,
Alexandre Ouss
,
Anna Füting
,
Laurent Roten
,
Bart A. Mulder
,
Martin H. Ruwald
,
Roberto Menè
,
Pepijn van der Voort
,
Nico Reinsch
,
Thomas Kueffer
,
Serge Bovéda
,
E Albrecht
,
Boris Schmidt
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1111/jce.16583
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1111/jce.16583
Background Real‐life data on efficacy and safety of pulsed‐field ablation (PFA) using the pentaspline multi‐electrode catheter in symptomatic atrial fibrillation (AF) patients is still scarce. Objective This study aims to assess the efficacy and safety of PFA in patients with persistent AF. Methods Data from early commercial use across seven European centers were collected in a registry. To confirm the efficacy and safety of extra pulmonary vein (PV) ablation, patients were categorized into two groups: those undergoing pulmonary vein isolation (PVI) alone and those receiving additional ablation. Procedural and follow‐up data were collected. Results The study included 448 patients (347 PVI only, 101 PVI + α ). In the PVI + α group, extra PV ablation included left atrial posterior wall isolation (87%), mitral isthmus ablation (37%), and cavo‐tricuspid isthmus ablation (3%). At 1‐year follow‐up, the PVI only group showed significantly fewer atrial tachyarrhythmia recurrences compared to PVI + α group (69% vs. 56%, p = 0.013). While AF recurrence did not significantly differ (25% vs. 28%, p = 0.713), PVI + α group had a significantly higher atrial tachycardia recurrence (8% vs. 22%, p < 0.001). Major complications occurred in 2.0% versus 1.0% (PVI only vs. PVI + α ), including pericardial tamponade (6 vs. 0; p = 0.345) and stroke (1 vs. 1; p = 0.400). Conclusions PVI plus extra PV ablation using a pentaspline PFA catheter is associated with a higher incidence of atrial tachycardia recurrences. For persistent AF, a simpler approach of performing only PVI may be more effective.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/jce.16583
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jce.16583
- OA Status
- hybrid
- Cited By
- 7
- References
- 29
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4409119219
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4409119219Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1111/jce.16583Digital Object Identifier
- Title
-
Pulsed‐Field Ablation for Persistent Atrial Fibrillation in EU‐PORIA RegistryWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-04-02Full publication date if available
- Authors
-
Jun Hirokami, K. R. Julian Chun, Stefano Bordignon, Shota Tohoku, Kars Neven, Tobias Reichlin, Yuri Blaauw, Jim Hansen, Raquel Adeliño, Alexandre Ouss, Anna Füting, Laurent Roten, Bart A. Mulder, Martin H. Ruwald, Roberto Menè, Pepijn van der Voort, Nico Reinsch, Thomas Kueffer, Serge Bovéda, E Albrecht, Boris SchmidtList of authors in order
- Landing page
-
https://doi.org/10.1111/jce.16583Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jce.16583Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jce.16583Direct OA link when available
- Concepts
-
Medicine, Atrial fibrillation, Ablation, Internal medicine, Cardiology, Atrial tachycardia, Pulmonary vein, Catheter ablation, Tamponade, Cardiac tamponade, Hazard ratio, Confidence intervalTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
7Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 7Per-year citation counts (last 5 years)
- References (count)
-
29Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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