Puupehenone, an Anticancer Produced by the Indonesian Marine Sponge Hyrtios sp. Article Swipe

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YOU? · · 2021 · Open Access · · DOI: https://doi.org/10.1088/1755-1315/869/1/012050

In a continuous study on the Indonesian marine sponges, we found a Hyrtios sponge during our expedition in Lhok Mata Ie, an isolated place around Aceh Besar, Indonesia in 2017. The bioassay-guided separation with several steps of chromatography was applied to give pure material. Moreover, the spectroscopic analysis revealed the presence of puupehenone ( 1 ), a unique class of merosesquiterpene together with its analogs ( 2 - 3 ). Their structures and bioactivity against multidrug-resistant Escherichia coli (MDR E. coli ) together with several cell lines are described here.

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Sponge Indonesian Bioassay Escherichia coli Biology Stereochemistry Botany Chemistry Biochemistry Ecology Gene Philosophy Linguistics

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Type: article
Language: en
Landing Page: https://doi.org/10.1088/1755-1315/869/1/012050
OA Status: diamond
Cited By: 1
References: 20
Related Works: 10
OpenAlex ID: https://openalex.org/W3211962631

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DOI: https://doi.org/10.1088/1755-1315/869/1/012050

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Title: Puupehenone, an Anticancer Produced by the Indonesian Marine Sponge Hyrtios sp.

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Type: article

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Language: en

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Publication year: 2021

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Publication date: 2021-11-01

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Authors: Viqqi Kurnianda, Musri Musman

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Landing page: https://doi.org/10.1088/1755-1315/869/1/012050

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Concepts: Sponge, Indonesian, Bioassay, Escherichia coli, Biology, Stereochemistry, Botany, Chemistry, Biochemistry, Ecology, Gene, Philosophy, Linguistics

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Cited by: 1

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