Python tooth–inspired fixation device for enhanced rotator cuff repair Article Swipe
Iden Kurtaliaj
,
Ethan D. Hoppe
,
Yuxuan Huang
,
David Ju
,
Jacob A. Sandler
,
Donghwan Yoon
,
Lester J. Smith
,
Silvio Torres Betancur
,
Linda Effiong
,
Thomas R. Gardner
,
Liana J. Tedesco
,
Sohil S. Desai
,
Victor Birman
,
William N. Levine
,
Guy M. Genin
,
Stavros Thomopoulos
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1126/sciadv.adl5270
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.1126/sciadv.adl5270
Rotator cuff repair surgeries fail frequently, with 20 to 94% of the 600,000 repairs performed annually in the United States resulting in retearing of the rotator cuff. The most common cause of failure is sutures tearing through tendons at grasping points. To address this issue, we drew inspiration from the specialized teeth of snakes of the Pythonoidea superfamily, which grasp soft tissues without tearing. To apply this nondamaging gripping approach to the surgical repair of tendon, we developed and optimized a python tooth–inspired device as an adjunct to current rotator cuff suture repair and found that it nearly doubled repair strength. Integrated simulations, 3D printing, and ex vivo experiments revealed a relationship between tooth shape and grasping mechanics, enabling optimization of the clinically relevant device that substantially enhances rotator cuff repair by distributing stresses over the attachment footprint. This approach suggests an alternative to traditional suturing paradigms and may reduce the risk of tendon retearing after rotator cuff repair.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1126/sciadv.adl5270
- https://www.science.org/doi/pdf/10.1126/sciadv.adl5270?download=true
- OA Status
- gold
- Cited By
- 4
- References
- 64
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4400113471
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4400113471Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1126/sciadv.adl5270Digital Object Identifier
- Title
-
Python tooth–inspired fixation device for enhanced rotator cuff repairWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2024Year of publication
- Publication date
-
2024-06-28Full publication date if available
- Authors
-
Iden Kurtaliaj, Ethan D. Hoppe, Yuxuan Huang, David Ju, Jacob A. Sandler, Donghwan Yoon, Lester J. Smith, Silvio Torres Betancur, Linda Effiong, Thomas R. Gardner, Liana J. Tedesco, Sohil S. Desai, Victor Birman, William N. Levine, Guy M. Genin, Stavros ThomopoulosList of authors in order
- Landing page
-
https://doi.org/10.1126/sciadv.adl5270Publisher landing page
- PDF URL
-
https://www.science.org/doi/pdf/10.1126/sciadv.adl5270?download=trueDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.science.org/doi/pdf/10.1126/sciadv.adl5270?download=trueDirect OA link when available
- Concepts
-
Rotator cuff, Tendon, Tearing, Fixation (population genetics), Medicine, Fibrous joint, Biomedical engineering, Surgery, Engineering, Mechanical engineering, Environmental health, PopulationTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
4Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 4Per-year citation counts (last 5 years)
- References (count)
-
64Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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