Quantitative Proteomic Analysis of Nile Tilapia Brain Following Sub–Chronically Exposed to Toxic Cyanobacteria Microcystis aeruginosa Article Swipe

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Hai Xu , Yuling Ding , Xuchun Qiu , Yohei Shimasaki , Yuji Oshima ·

YOU? · · 2020 · Open Access · · DOI: https://doi.org/10.5109/4103892

In the present study, we investigated the effects of Microcytis on Nile tilapia brain. Male Nile tilapia were exposed to lyophilized Microcytis aeruginosa for 28 days. An isobaric Tags for Relative and Absolute Quantitation (iTRAQ) approach coupled with nano high–performance liquid chromatography–tandem mass spectrometry (nano HPLC–MS/MS) analysis was employed to detect and identify the differential expressed proteins. A total of 49 proteins were successfully identified and categorized into functional classes that mostly included metabolism, ubiquitin–proteasome, signal transduction and transporting, indicating that Microcytis toxicity in the fish brain is complex and diverse. Our proteomic analyses added new perspective to Microcytis neurotoxicity in aquatic organisms.

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Microcystis aeruginosa Nile tilapia Cyanobacteria Microcystis Biology Chemistry Microbiology Fish <Actinopterygii> Fishery Bacteria Oreochromis Genetics

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Type: article
Language: en
Landing Page: https://doi.org/10.5109/4103892
PDF: https://catalog.lib.kyushu-u.ac.jp/opac_download_md/4103892/p283.pdf
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DOI: https://doi.org/10.5109/4103892

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Title: Quantitative Proteomic Analysis of Nile Tilapia Brain Following Sub–Chronically Exposed to Toxic Cyanobacteria Microcystis aeruginosa

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Language: en

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Publication year: 2020

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Publication date: 2020-09-01

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Authors: Hai Xu, Yuling Ding, Xuchun Qiu, Yohei Shimasaki, Yuji Oshima

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Landing page: https://doi.org/10.5109/4103892

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Concepts: Microcystis aeruginosa, Nile tilapia, Cyanobacteria, Microcystis, Biology, Chemistry, Microbiology, Fish , Fishery, Bacteria, Oreochromis, Genetics

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citation_normalized_percentile.value	0.10479213
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	False