RARE-61. BODY COMPOSITION AND NUCHAL SKINFOLD THICKNESS IN PEDIATRIC BRAIN TUMOR PATIENTS Article Swipe
Junxiang Peng
,
Svenja Boekhoff
,
Maria Eveslage
,
Brigitte Bison
,
Panjarat Sowithayasakul
,
Hermann L. Müller
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1093/neuonc/noaa222.771
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1093/neuonc/noaa222.771
BACKGROUND Obesity, cardiovascular disease (CVD), and relapse/progression have major impact on prognosis in pediatric brain tumor (BT) patients. Cranial MRI is part of routine follow-up. METHODS In a cross-sectional study, we analyzed nuchal skinfold thickness (NST) on MRI performed for BT follow-up monitoring as a novel parameter for body composition (BC) and CVD in 177 BT patients (40 WHO grade 1–2 BT; 31 grade 3–4 BT; 106 craniopharyngioma (CP)), and 53 healthy controls (HC). Associations of NST with body mass index (BMI), waist-to-height ratio (WHtR), caliper-measured skinfold thickness (cSFT), and blood pressure (BP) were analysed in BT and HC. RESULTS CP patients showed higher BMI, WHtR, NST and cSFT when compared with BT and HC, whereas these differences were not detectable between BT and HC. However, WHO grade 1–2 BT patients were observed with higher BMI, waist circumference and triceps cSFT when compared to WHO grade 3–4 BT patients. NST showed high correlations with BMI, WHtR, and cSFT. NST, BMI and WHtR had predictive value for CVD in terms of increased BP, and in multivariate analysis, only BMI was selected for the final model resulting in an odds ratio of 1.25 (1.14–1.379). In CP patients with hypothalamic involvement/lesion or gross-total resection, rate and degree of obesity were increased. CONCLUSIONS As monitoring of MRI and BC play an important role in follow-up after BT, NST could serve as a novel useful parameter for assessment of BC and CVD risk in BT patients.
Related Topics
Concepts
Medicine
Waist-to-height ratio
Body mass index
Waist
Obesity
Odds ratio
Internal medicine
Cardiology
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1093/neuonc/noaa222.771
- https://academic.oup.com/neuro-oncology/article-pdf/22/Supplement_3/iii455/34688101/noaa222.771.pdf
- OA Status
- hybrid
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3185707902
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3185707902Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1093/neuonc/noaa222.771Digital Object Identifier
- Title
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RARE-61. BODY COMPOSITION AND NUCHAL SKINFOLD THICKNESS IN PEDIATRIC BRAIN TUMOR PATIENTSWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2020Year of publication
- Publication date
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2020-12-01Full publication date if available
- Authors
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Junxiang Peng, Svenja Boekhoff, Maria Eveslage, Brigitte Bison, Panjarat Sowithayasakul, Hermann L. MüllerList of authors in order
- Landing page
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https://doi.org/10.1093/neuonc/noaa222.771Publisher landing page
- PDF URL
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https://academic.oup.com/neuro-oncology/article-pdf/22/Supplement_3/iii455/34688101/noaa222.771.pdfDirect link to full text PDF
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YesWhether a free full text is available
- OA status
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hybridOpen access status per OpenAlex
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https://academic.oup.com/neuro-oncology/article-pdf/22/Supplement_3/iii455/34688101/noaa222.771.pdfDirect OA link when available
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Medicine, Waist-to-height ratio, Body mass index, Waist, Obesity, Odds ratio, Internal medicine, CardiologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
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0Total citation count in OpenAlex
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10Other works algorithmically related by OpenAlex
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| best_oa_location.source.host_organization_lineage_names | Oxford University Press, University of Oxford |
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| best_oa_location.version | publishedVersion |
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| best_oa_location.license_id | https://openalex.org/licenses/cc-by-nc |
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| primary_location.source.host_organization_lineage_names | Oxford University Press, University of Oxford |
| primary_location.license | cc-by-nc |
| primary_location.pdf_url | https://academic.oup.com/neuro-oncology/article-pdf/22/Supplement_3/iii455/34688101/noaa222.771.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by-nc |
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| primary_location.is_published | True |
| primary_location.raw_source_name | Neuro-Oncology |
| primary_location.landing_page_url | https://doi.org/10.1093/neuonc/noaa222.771 |
| publication_date | 2020-12-01 |
| publication_year | 2020 |
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