Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22 Article Swipe

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Elisia Villemure , Tom Januario , Mingshuo Zeng , Hanna G. Budayeva , Benjamin T. Walters , Aaron Lictao , Ke Sherry Li , Xiaofen Ye , Caroline L. Gilchrist , Bridget Hoag , Nicholas F. Endres , Peter Hsu , John S.D. Chan , Tommy K. Cheung , Michael R. Costa , Jean‐Philippe Fortin , Noriko Ishisoko , Brett M. Babin , Joyce Liu , Alexandra Frommlet , Joachim Rudolph , Robert L. Yauch ·

YOU? · · 2025 · Open Access · · DOI: https://doi.org/10.1038/s41467-025-64669-4

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Type: article
Language: en
Landing Page: https://doi.org/10.1038/s41467-025-64669-4
PDF: https://www.nature.com/articles/s41467-025-64669-4.pdf
OA Status: gold
Cited By: 1
References: 53
OpenAlex ID: https://openalex.org/W4415808337

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OpenAlex ID: https://openalex.org/W4415808337

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DOI: https://doi.org/10.1038/s41467-025-64669-4

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Title: Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22

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Type: article

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Language: en

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Publication year: 2025

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Publication date: 2025-11-03

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Authors: Elisia Villemure, Tom Januario, Mingshuo Zeng, Hanna G. Budayeva, Benjamin T. Walters, Aaron Lictao, Ke Sherry Li, Xiaofen Ye, Caroline L. Gilchrist, Bridget Hoag, Nicholas F. Endres, Peter Hsu, John S.D. Chan, Tommy K. Cheung, Michael R. Costa, Jean‐Philippe Fortin, Noriko Ishisoko, Brett M. Babin, Joyce Liu, Alexandra Frommlet, Joachim Rudolph, Robert L. Yauch

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Landing page: https://doi.org/10.1038/s41467-025-64669-4

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PDF URL: https://www.nature.com/articles/s41467-025-64669-4.pdf

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OA status: gold

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OA URL: https://www.nature.com/articles/s41467-025-64669-4.pdf

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Cited by: 1

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Citations by year (recent): 2025: 1

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References (count): 53

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