Rational Drug Therapy for the Management of Diabetes Mellitus Article Swipe
YOU?
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· 2022
· Open Access
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· DOI: https://doi.org/10.53350/pjmhs22168902
Diabetes Mellitus is one of the major worldwide public health issues, along with socio-economic growth. Diabetes Mellitus is a chronic metabolic syndrome of several causes characterized by long-lasting hyperglycemia with the turmoil of carbohydrates. The study aimed to evaluate pharmacotherapy on rational grounds for drug-drug interactions, polypharmacy, and untreated conditions if any., For the recording of patient case histories, a standard questionnaire was designed, which includes age, sex, history, chief complaints, Clinical tests, diagnosis & patient’s family history, etc., the copy of which is appended. Considering 20 cases, different parameters were studied which showed that 17 out of 20 cases received rational therapy according to standard pharmacotherapy and the patients responded well to the prescribed therapy, 3 cases out of 20 received irrational therapy due to which they showed poor response. The percentage of the female patient was 40% and the male patient was 60%. In some of these cases, drug interactions were found and their percentage was 22.1%. The most prominent interaction occurrence was of Ramipril with metformin i.e. 18.75% and Ciprofloxacin interaction with glimepiride is 6.25% etc. In all cases, a total of 86 drugs related problems were reported. The percentage of untreated conditions was 9.3%, drug without indication 6.98%, and cost-related problems were 20.9%, etc. In some cases, concurrent diseases were also found i.e. hypertension at 37.5% and asthma at 25 was prominent. Patients with ages between 41-50 and 51-60 years have a high percentage of Diabetes Mellitus i.e. 40% and 40% respectively. The most prominent ADRs were insomnia, skin rashes, dizziness, nausea, vomiting, diarrhea, etc. Nausea, vomiting, and diarrhea are more frequent with antibiotics. Keywords: Epidemiology, Etiology, Pathophysiology, Investigations, Complications and Treatment of Diabetes Mellitus
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.53350/pjmhs22168902
- https://pjmhsonline.com/index.php/pjmhs/article/download/2714/2679
- OA Status
- gold
- References
- 25
- Related Works
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- OpenAlex ID
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Raw OpenAlex JSON
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https://openalex.org/W4313155023Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.53350/pjmhs22168902Digital Object Identifier
- Title
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Rational Drug Therapy for the Management of Diabetes MellitusWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2022Year of publication
- Publication date
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2022-08-31Full publication date if available
- Authors
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Fawad Mahmood, Shahid Anwar, Ayesha Javaid, Moiz Inam Khan, Bilal Ahmed, Abad KhanList of authors in order
- Landing page
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https://doi.org/10.53350/pjmhs22168902Publisher landing page
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https://pjmhsonline.com/index.php/pjmhs/article/download/2714/2679Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://pjmhsonline.com/index.php/pjmhs/article/download/2714/2679Direct OA link when available
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Medicine, Pharmacotherapy, Polypharmacy, Diabetes mellitus, Ramipril, Metformin, Drug, Glimepiride, Family history, Internal medicine, Medical prescription, Pediatrics, Pharmacology, Endocrinology, Blood pressureTop concepts (fields/topics) attached by OpenAlex
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0Total citation count in OpenAlex
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25Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.20 | 86, 98, 120 |
| abstract_inverted_index.25 | 223 |
| abstract_inverted_index.86 | 185 |
| abstract_inverted_index.In | 145, 179, 208 |
| abstract_inverted_index.at | 218, 222 |
| abstract_inverted_index.by | 26 |
| abstract_inverted_index.if | 50 |
| abstract_inverted_index.is | 2, 17, 83, 176 |
| abstract_inverted_index.of | 4, 22, 32, 55, 81, 97, 119, 133, 147, 165, 184, 193, 238, 276 |
| abstract_inverted_index.on | 40 |
| abstract_inverted_index.to | 37, 104, 112, 125 |
| abstract_inverted_index.40% | 138, 242, 244 |
| abstract_inverted_index.For | 52 |
| abstract_inverted_index.The | 34, 131, 159, 191, 246 |
| abstract_inverted_index.all | 180 |
| abstract_inverted_index.and | 47, 107, 139, 154, 171, 202, 220, 231, 243, 261, 274 |
| abstract_inverted_index.are | 263 |
| abstract_inverted_index.due | 124 |
| abstract_inverted_index.for | 43 |
| abstract_inverted_index.one | 3 |
| abstract_inverted_index.out | 96, 118 |
| abstract_inverted_index.the | 5, 30, 53, 79, 108, 113, 134, 140 |
| abstract_inverted_index.was | 62, 137, 143, 157, 164, 196, 224 |
| abstract_inverted_index.60%. | 144 |
| abstract_inverted_index.ADRs | 249 |
| abstract_inverted_index.age, | 66 |
| abstract_inverted_index.ages | 228 |
| abstract_inverted_index.also | 214 |
| abstract_inverted_index.case | 57 |
| abstract_inverted_index.copy | 80 |
| abstract_inverted_index.drug | 150, 198 |
| abstract_inverted_index.etc. | 178, 207, 258 |
| abstract_inverted_index.have | 234 |
| abstract_inverted_index.high | 236 |
| abstract_inverted_index.i.e. | 169, 216, 241 |
| abstract_inverted_index.male | 141 |
| abstract_inverted_index.more | 264 |
| abstract_inverted_index.most | 160, 247 |
| abstract_inverted_index.poor | 129 |
| abstract_inverted_index.sex, | 67 |
| abstract_inverted_index.skin | 252 |
| abstract_inverted_index.some | 146, 209 |
| abstract_inverted_index.that | 94 |
| abstract_inverted_index.they | 127 |
| abstract_inverted_index.well | 111 |
| abstract_inverted_index.were | 90, 152, 189, 205, 213, 250 |
| abstract_inverted_index.with | 12, 29, 167, 174, 227, 266 |
| abstract_inverted_index.& | 74 |
| abstract_inverted_index.37.5% | 219 |
| abstract_inverted_index.41-50 | 230 |
| abstract_inverted_index.51-60 | 232 |
| abstract_inverted_index.6.25% | 177 |
| abstract_inverted_index.9.3%, | 197 |
| abstract_inverted_index.aimed | 36 |
| abstract_inverted_index.along | 11 |
| abstract_inverted_index.any., | 51 |
| abstract_inverted_index.cases | 99, 117 |
| abstract_inverted_index.chief | 69 |
| abstract_inverted_index.drugs | 186 |
| abstract_inverted_index.etc., | 78 |
| abstract_inverted_index.found | 153, 215 |
| abstract_inverted_index.major | 6 |
| abstract_inverted_index.study | 35 |
| abstract_inverted_index.their | 155 |
| abstract_inverted_index.these | 148 |
| abstract_inverted_index.total | 183 |
| abstract_inverted_index.which | 64, 82, 92, 126 |
| abstract_inverted_index.years | 233 |
| abstract_inverted_index.18.75% | 170 |
| abstract_inverted_index.20.9%, | 206 |
| abstract_inverted_index.22.1%. | 158 |
| abstract_inverted_index.6.98%, | 201 |
| abstract_inverted_index.asthma | 221 |
| abstract_inverted_index.cases, | 87, 149, 181, 210 |
| abstract_inverted_index.causes | 24 |
| abstract_inverted_index.family | 76 |
| abstract_inverted_index.female | 135 |
| abstract_inverted_index.health | 9 |
| abstract_inverted_index.public | 8 |
| abstract_inverted_index.showed | 93, 128 |
| abstract_inverted_index.tests, | 72 |
| abstract_inverted_index.Nausea, | 259 |
| abstract_inverted_index.between | 229 |
| abstract_inverted_index.chronic | 19 |
| abstract_inverted_index.grounds | 42 |
| abstract_inverted_index.growth. | 14 |
| abstract_inverted_index.issues, | 10 |
| abstract_inverted_index.nausea, | 255 |
| abstract_inverted_index.patient | 56, 136, 142 |
| abstract_inverted_index.rashes, | 253 |
| abstract_inverted_index.related | 187 |
| abstract_inverted_index.several | 23 |
| abstract_inverted_index.studied | 91 |
| abstract_inverted_index.therapy | 102, 123 |
| abstract_inverted_index.turmoil | 31 |
| abstract_inverted_index.without | 199 |
| abstract_inverted_index.Clinical | 71 |
| abstract_inverted_index.Diabetes | 0, 15, 239, 277 |
| abstract_inverted_index.Mellitus | 1, 16, 240, 278 |
| abstract_inverted_index.Patients | 226 |
| abstract_inverted_index.Ramipril | 166 |
| abstract_inverted_index.diarrhea | 262 |
| abstract_inverted_index.diseases | 212 |
| abstract_inverted_index.evaluate | 38 |
| abstract_inverted_index.frequent | 265 |
| abstract_inverted_index.history, | 68, 77 |
| abstract_inverted_index.includes | 65 |
| abstract_inverted_index.patients | 109 |
| abstract_inverted_index.problems | 188, 204 |
| abstract_inverted_index.rational | 41, 101 |
| abstract_inverted_index.received | 100, 121 |
| abstract_inverted_index.standard | 60, 105 |
| abstract_inverted_index.syndrome | 21 |
| abstract_inverted_index.therapy, | 115 |
| abstract_inverted_index.Etiology, | 270 |
| abstract_inverted_index.Keywords: | 268 |
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| abstract_inverted_index.appended. | 84 |
| abstract_inverted_index.designed, | 63 |
| abstract_inverted_index.diagnosis | 73 |
| abstract_inverted_index.diarrhea, | 257 |
| abstract_inverted_index.different | 88 |
| abstract_inverted_index.drug-drug | 44 |
| abstract_inverted_index.insomnia, | 251 |
| abstract_inverted_index.metabolic | 20 |
| abstract_inverted_index.metformin | 168 |
| abstract_inverted_index.prominent | 161, 248 |
| abstract_inverted_index.recording | 54 |
| abstract_inverted_index.reported. | 190 |
| abstract_inverted_index.responded | 110 |
| abstract_inverted_index.response. | 130 |
| abstract_inverted_index.untreated | 48, 194 |
| abstract_inverted_index.vomiting, | 256, 260 |
| abstract_inverted_index.worldwide | 7 |
| abstract_inverted_index.concurrent | 211 |
| abstract_inverted_index.conditions | 49, 195 |
| abstract_inverted_index.dizziness, | 254 |
| abstract_inverted_index.histories, | 58 |
| abstract_inverted_index.indication | 200 |
| abstract_inverted_index.irrational | 122 |
| abstract_inverted_index.occurrence | 163 |
| abstract_inverted_index.parameters | 89 |
| abstract_inverted_index.percentage | 132, 156, 192, 237 |
| abstract_inverted_index.prescribed | 114 |
| abstract_inverted_index.prominent. | 225 |
| abstract_inverted_index.Considering | 85 |
| abstract_inverted_index.complaints, | 70 |
| abstract_inverted_index.glimepiride | 175 |
| abstract_inverted_index.interaction | 162, 173 |
| abstract_inverted_index.patient’s | 75 |
| abstract_inverted_index.antibiotics. | 267 |
| abstract_inverted_index.cost-related | 203 |
| abstract_inverted_index.hypertension | 217 |
| abstract_inverted_index.interactions | 151 |
| abstract_inverted_index.long-lasting | 27 |
| abstract_inverted_index.Ciprofloxacin | 172 |
| abstract_inverted_index.Complications | 273 |
| abstract_inverted_index.Epidemiology, | 269 |
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| abstract_inverted_index.hyperglycemia | 28 |
| abstract_inverted_index.interactions, | 45 |
| abstract_inverted_index.polypharmacy, | 46 |
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| abstract_inverted_index.respectively. | 245 |
| abstract_inverted_index.carbohydrates. | 33 |
| abstract_inverted_index.socio-economic | 13 |
| abstract_inverted_index.Investigations, | 272 |
| abstract_inverted_index.pharmacotherapy | 39, 106 |
| abstract_inverted_index.Pathophysiology, | 271 |
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| institutions_distinct_count | 6 |
| corresponding_institution_ids | https://openalex.org/I4210142599 |
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