Recent advance in phytonanomedicine and mineral nanomedicine delivery system of the treatment for acute myeloid leukemia Article Swipe
Yimin Jia
,
Cun Sun
,
Ting Chen
,
Hui Zhu
,
Tian‐Rui Wang
,
Yan Ye
,
Xing Luo
,
Xiaoqiang Zeng
,
Yun Yang
,
Hao Zeng
,
Quanming Zou
,
E. Liu
,
Jieping Li
,
Hongwu Sun
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1186/s12951-023-01968-2
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.1186/s12951-023-01968-2
Acute myeloid leukemia (AML) is an invasive hematopoietic malignancy caused by excessive proliferation of myeloblasts. Classical chemotherapies and cell transplantation therapies have remarkable efficacy in AML treatment; however, 30–40% of patients relapsed or had refractory disease. The resistance of AML is closely related to its inherent cytogenetics or various gene mutations. Recently, phytonanomedicine are found to be effective against resistant AML cells and have become a research focus for nanotechnology development to improve their properties, such as increasing solubility, improving absorption, enhancing bioavailability, and maintaining sustained release and targeting. These novel phytonanomedicine and mineral nanomedicine, including nanocrystals, nanoemulsion, nanoparticles, nanoliposome, and nanomicelles, offer many advantages, such as flexible dosages or forms, multiple routes of administration, and curative effects. Therefore, we reviewed the application and progress of phytomedicine in AML treatment and discussed the limitations and future prospects. This review may provide a solid reference to guide future research on AML treatment.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1186/s12951-023-01968-2
- https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-023-01968-2
- OA Status
- gold
- Cited By
- 9
- References
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- Related Works
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- OpenAlex ID
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All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4385265001Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1186/s12951-023-01968-2Digital Object Identifier
- Title
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Recent advance in phytonanomedicine and mineral nanomedicine delivery system of the treatment for acute myeloid leukemiaWork title
- Type
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reviewOpenAlex work type
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-07-26Full publication date if available
- Authors
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Yimin Jia, Cun Sun, Ting Chen, Hui Zhu, Tian‐Rui Wang, Yan Ye, Xing Luo, Xiaoqiang Zeng, Yun Yang, Hao Zeng, Quanming Zou, E. Liu, Jieping Li, Hongwu SunList of authors in order
- Landing page
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https://doi.org/10.1186/s12951-023-01968-2Publisher landing page
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https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-023-01968-2Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-023-01968-2Direct OA link when available
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Myeloid leukemia, Nanomedicine, Medicine, Homoharringtonine, Pharmacology, Cancer research, Nanotechnology, Materials science, NanoparticleTop concepts (fields/topics) attached by OpenAlex
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9Total citation count in OpenAlex
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2025: 3, 2024: 6Per-year citation counts (last 5 years)
- References (count)
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105Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.proliferation | 13 |
| abstract_inverted_index.chemotherapies | 17 |
| abstract_inverted_index.nanoparticles, | 99 |
| abstract_inverted_index.nanotechnology | 70 |
| abstract_inverted_index.administration, | 115 |
| abstract_inverted_index.transplantation | 20 |
| abstract_inverted_index.bioavailability, | 83 |
| abstract_inverted_index.phytonanomedicine | 53, 92 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 97 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 14 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.5299999713897705 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.8433035 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |