Recent Advances in Metal-Organic Framework (MOF) Asymmetric Membranes/Composites for Biomedical Applications Article Swipe
Farrokhfar Valizadeh Harzand
,
Seyyed Navid Mousavi Nejad
,
Aziz Babapoor
,
Seyyed Mojtaba Mousavi
,
Seyyed Alireza Hashemi
,
Ahmad Gholami
,
Wei‐Hung Chiang
,
Maria Giovanna Buonomenna
,
Chin Wei Lai
·
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/sym15020403
YOU?
·
· 2023
· Open Access
·
· DOI: https://doi.org/10.3390/sym15020403
Metal-organic frameworks (MOFs) are a new class of porous crystalline materials composed of metal and organic material. MOFs have fascinating properties, such as fine tunability, large specific surface area, and high porosity. MOFs are widely used for environmental protection, biosensors, regenerative medicine, medical engineering, cell therapy, catalysts, and drug delivery. Recent studies have reported various significant properties of MOFs for biomedical applications, such as drug detection and delivery. In contrast, MOFs have limitations such as low stability and low specificity in binding to the target. MOF-based membranes improve the stability and specificity of conventional MOFs by increasing the surface area and developing the possibility of MOF-ligand binding, while conjugated membranes dramatically increase the area of active functional groups. This special property makes them attractive for drug and biosensor fabrication, as both the spreading and solubility components of the porosity can be changed. Asymmetric membranes are a structure with high potential in the biomedical field, due to the different characteristics on its two surfaces, the possibility of adjusting various properties such as the size of porosity, transfer rate and selectivity, and surface properties such as hydrophilicity and hydrophobicity. MOF assisted asymmetric membranes can provide a platform with different properties and characteristics in the biomedical field. The latest version of MOF materials/membranes has several potential applications, especially in medical engineering, cell therapy, drug delivery, and regenerative medicine, which will be discussed in this review, along with their advantages, disadvantages, and challenges.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/sym15020403
- https://www.mdpi.com/2073-8994/15/2/403/pdf?version=1675402968
- OA Status
- gold
- Cited By
- 34
- References
- 188
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4319083611
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4319083611Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/sym15020403Digital Object Identifier
- Title
-
Recent Advances in Metal-Organic Framework (MOF) Asymmetric Membranes/Composites for Biomedical ApplicationsWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
-
2023-02-03Full publication date if available
- Authors
-
Farrokhfar Valizadeh Harzand, Seyyed Navid Mousavi Nejad, Aziz Babapoor, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Wei‐Hung Chiang, Maria Giovanna Buonomenna, Chin Wei LaiList of authors in order
- Landing page
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https://doi.org/10.3390/sym15020403Publisher landing page
- PDF URL
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https://www.mdpi.com/2073-8994/15/2/403/pdf?version=1675402968Direct link to full text PDF
- Open access
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://www.mdpi.com/2073-8994/15/2/403/pdf?version=1675402968Direct OA link when available
- Concepts
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Membrane, Materials science, Nanotechnology, Drug delivery, Metal-organic framework, Porosity, Biosensor, Characterisation of pore space in soil, Surface engineering, Chemistry, Composite material, Organic chemistry, Adsorption, BiochemistryTop concepts (fields/topics) attached by OpenAlex
- Cited by
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34Total citation count in OpenAlex
- Citations by year (recent)
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2025: 9, 2024: 20, 2023: 5Per-year citation counts (last 5 years)
- References (count)
-
188Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
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