Recent Advances of Pharmacological Intervention of Hyperlipidemia: A Comprehensive Review Article Swipe
Sharanabasava S Biradar
,
M. Ajmal Ali
,
Syed Sagheer Ahmed
,
K. Chandan
,
B. M. Jayanth
,
D. R. Bharathi
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.4103/ajprhc.ajprhc_121_24
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.4103/ajprhc.ajprhc_121_24
Hyperlipidemia is characterized by high blood levels of lipids, especially cholesterol and triglycerides. The occurrence of cardiovascular (CV) disorders such as atherosclerosis, heart disease, and stroke are all significantly increased by this condition. A review of the pathophysiology, clinical implications, and treatment options for hyperlipidemia is intended in this abstract. Elevated cholesterol levels are a common metabolic condition that has serious clinical ramifications, especially for CV health. Its development is influenced by genetic and lifestyle factors, which cause lipid abnormalities in the blood and the start of atherosclerosis. A person’s levels of lipids and risk factors for CV disease are taken into account when developing pharmaceutical therapies and lifestyle changes for effective management. A comprehensive evaluation of pharmaceutical therapies for hyperlipidemia is also presented in this abstract. The purpose of the review is to assess the effectiveness, safety, and relative efficacy of different lipid-lowering medications, such as fibrates, ezetimibe, statins, proprotein convertase subtilisin/kexin type 9 inhibitors, and new and developing treatments. This comprehensive review offers important insights into the best choice and sequencing of pharmaceutical therapies based on individual patient characteristics, lipid profile, and risk assessment by combining data from randomized controlled trials and meta-analyses.
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Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.4103/ajprhc.ajprhc_121_24
- OA Status
- diamond
- Cited By
- 1
- References
- 43
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All OpenAlex metadata
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https://openalex.org/W4410836695Canonical identifier for this work in OpenAlex
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https://doi.org/10.4103/ajprhc.ajprhc_121_24Digital Object Identifier
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Recent Advances of Pharmacological Intervention of Hyperlipidemia: A Comprehensive ReviewWork title
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reviewOpenAlex work type
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enPrimary language
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2025Year of publication
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2025-01-01Full publication date if available
- Authors
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Sharanabasava S Biradar, M. Ajmal Ali, Syed Sagheer Ahmed, K. Chandan, B. M. Jayanth, D. R. BharathiList of authors in order
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https://doi.org/10.4103/ajprhc.ajprhc_121_24Publisher landing page
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://doi.org/10.4103/ajprhc.ajprhc_121_24Direct OA link when available
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Hyperlipidemia, Intervention (counseling), Medicine, Endocrinology, Psychiatry, Diabetes mellitusTop concepts (fields/topics) attached by OpenAlex
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1Total citation count in OpenAlex
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2025: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.treatments. | 160 |
| abstract_inverted_index.medications, | 144 |
| abstract_inverted_index.abnormalities | 79 |
| abstract_inverted_index.characterized | 2 |
| abstract_inverted_index.comprehensive | 114, 162 |
| abstract_inverted_index.implications, | 39 |
| abstract_inverted_index.significantly | 28 |
| abstract_inverted_index.Hyperlipidemia | 0 |
| abstract_inverted_index.cardiovascular | 16 |
| abstract_inverted_index.effectiveness, | 136 |
| abstract_inverted_index.hyperlipidemia | 44, 120 |
| abstract_inverted_index.lipid-lowering | 143 |
| abstract_inverted_index.meta-analyses. | 194 |
| abstract_inverted_index.pharmaceutical | 105, 117, 174 |
| abstract_inverted_index.ramifications, | 62 |
| abstract_inverted_index.triglycerides. | 12 |
| abstract_inverted_index.atherosclerosis, | 21 |
| abstract_inverted_index.atherosclerosis. | 87 |
| abstract_inverted_index.characteristics, | 180 |
| abstract_inverted_index.pathophysiology, | 37 |
| abstract_inverted_index.subtilisin/kexin | 152 |
| cited_by_percentile_year.max | 95 |
| cited_by_percentile_year.min | 91 |
| countries_distinct_count | 0 |
| institutions_distinct_count | 6 |
| citation_normalized_percentile.value | 0.90701833 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | True |