Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis Article Swipe
Nitikorn Poriswanish
,
Rita Neumann
,
Jon H. Wetton
,
J. Wagstaff
,
Maarten Larmuseau
,
Mark A. Jobling
,
Celia A. May
·
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1371/journal.pgen.1007680
YOU?
·
· 2018
· Open Access
·
· DOI: https://doi.org/10.1371/journal.pgen.1007680
The human X and Y chromosomes are heteromorphic but share a region of homology at the tips of their short arms, pseudoautosomal region 1 (PAR1), that supports obligate crossover in male meiosis. Although the boundary between pseudoautosomal and sex-specific DNA has traditionally been regarded as conserved among primates, it was recently discovered that the boundary position varies among human males, due to a translocation of ~110 kb from the X to the Y chromosome that creates an extended PAR1 (ePAR). This event has occurred at least twice in human evolution. So far, only limited evidence has been presented to suggest this extension is recombinationally active. Here, we sought direct proof by examining thousands of gametes from each of two ePAR-carrying men, for two subregions chosen on the basis of previously published male X-chromosomal meiotic double-strand break (DSB) maps. Crossover activity comparable to that seen at autosomal hotspots was observed between the X and the ePAR borne on the Y chromosome both at a distal and a proximal site within the 110-kb extension. Other hallmarks of classic recombination hotspots included evidence of transmission distortion and GC-biased gene conversion. We observed good correspondence between the male DSB clusters and historical recombination activity of this region in the X chromosomes of females, as ascertained from linkage disequilibrium analysis; this suggests that this region is similarly primed for crossover in both male and female germlines, although sex-specific differences may also exist. Extensive resequencing and inference of ePAR haplotypes, placed in the framework of the Y phylogeny as ascertained by both Y microsatellites and single nucleotide polymorphisms, allowed us to estimate a minimum rate of crossover over the entire ePAR region of 6-fold greater than genome average, comparable with pedigree estimates of PAR1 activity generally. We conclude ePAR very likely contributes to the critical crossover function of PAR1.
Related Topics
Concepts
Pseudoautosomal region
Biology
Chromosomal crossover
Genetics
Meiosis
Recombination
Evolutionary biology
Y chromosome
Gene conversion
X chromosome
Haplotype
Meiotic drive
Homologous recombination
Linkage disequilibrium
Chromosome
Gene
Allele
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1371/journal.pgen.1007680
- https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printable
- OA Status
- gold
- Cited By
- 10
- References
- 73
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W2894919995
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W2894919995Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1371/journal.pgen.1007680Digital Object Identifier
- Title
-
Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysisWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2018Year of publication
- Publication date
-
2018-10-08Full publication date if available
- Authors
-
Nitikorn Poriswanish, Rita Neumann, Jon H. Wetton, J. Wagstaff, Maarten Larmuseau, Mark A. Jobling, Celia A. MayList of authors in order
- Landing page
-
https://doi.org/10.1371/journal.pgen.1007680Publisher landing page
- PDF URL
-
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printableDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printableDirect OA link when available
- Concepts
-
Pseudoautosomal region, Biology, Chromosomal crossover, Genetics, Meiosis, Recombination, Evolutionary biology, Y chromosome, Gene conversion, X chromosome, Haplotype, Meiotic drive, Homologous recombination, Linkage disequilibrium, Chromosome, Gene, AlleleTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
10Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2022: 2, 2021: 1, 2020: 3, 2019: 3Per-year citation counts (last 5 years)
- References (count)
-
73Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W2894919995 |
|---|---|
| doi | https://doi.org/10.1371/journal.pgen.1007680 |
| ids.doi | https://doi.org/10.1371/journal.pgen.1007680 |
| ids.mag | 2894919995 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/30296256 |
| ids.openalex | https://openalex.org/W2894919995 |
| fwci | 1.23599054 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000328 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Adult |
| mesh[1].qualifier_ui | Q000379 |
| mesh[1].descriptor_ui | D002874 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | methods |
| mesh[1].descriptor_name | Chromosome Mapping |
| mesh[2].qualifier_ui | |
| mesh[2].descriptor_ui | D002875 |
| mesh[2].is_major_topic | False |
| mesh[2].qualifier_name | |
| mesh[2].descriptor_name | Chromosomes |
| mesh[3].qualifier_ui | Q000235 |
| mesh[3].descriptor_ui | D041321 |
| mesh[3].is_major_topic | False |
| mesh[3].qualifier_name | genetics |
| mesh[3].descriptor_name | Chromosomes, Human, X |
| mesh[4].qualifier_ui | Q000235 |
| mesh[4].descriptor_ui | D041322 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | genetics |
| mesh[4].descriptor_name | Chromosomes, Human, Y |
| mesh[5].qualifier_ui | Q000235 |
| mesh[5].descriptor_ui | D003434 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | genetics |
| mesh[5].descriptor_name | Crossing Over, Genetic |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D053903 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | DNA Breaks, Double-Stranded |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D008040 |
| mesh[7].is_major_topic | False |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Genetic Linkage |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D016678 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Genome |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D006239 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Haplotypes |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D006801 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Humans |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D008297 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Male |
| mesh[12].qualifier_ui | Q000235 |
| mesh[12].descriptor_ui | D020641 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | genetics |
| mesh[12].descriptor_name | Polymorphism, Single Nucleotide |
| mesh[13].qualifier_ui | Q000235 |
| mesh[13].descriptor_ui | D000071439 |
| mesh[13].is_major_topic | False |
| mesh[13].qualifier_name | genetics |
| mesh[13].descriptor_name | Pseudoautosomal Regions |
| mesh[14].qualifier_ui | Q000235 |
| mesh[14].descriptor_ui | D011995 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | genetics |
| mesh[14].descriptor_name | Recombination, Genetic |
| mesh[15].qualifier_ui | Q000166 |
| mesh[15].descriptor_ui | D013094 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | cytology |
| mesh[15].descriptor_name | Spermatozoa |
| mesh[16].qualifier_ui | |
| mesh[16].descriptor_ui | D000328 |
| mesh[16].is_major_topic | False |
| mesh[16].qualifier_name | |
| mesh[16].descriptor_name | Adult |
| mesh[17].qualifier_ui | Q000379 |
| mesh[17].descriptor_ui | D002874 |
| mesh[17].is_major_topic | False |
| mesh[17].qualifier_name | methods |
| mesh[17].descriptor_name | Chromosome Mapping |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D002875 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Chromosomes |
| mesh[19].qualifier_ui | Q000235 |
| mesh[19].descriptor_ui | D041321 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | genetics |
| mesh[19].descriptor_name | Chromosomes, Human, X |
| mesh[20].qualifier_ui | Q000235 |
| mesh[20].descriptor_ui | D041322 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | genetics |
| mesh[20].descriptor_name | Chromosomes, Human, Y |
| mesh[21].qualifier_ui | Q000235 |
| mesh[21].descriptor_ui | D003434 |
| mesh[21].is_major_topic | False |
| mesh[21].qualifier_name | genetics |
| mesh[21].descriptor_name | Crossing Over, Genetic |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D053903 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | DNA Breaks, Double-Stranded |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D008040 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Genetic Linkage |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D016678 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Genome |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D006239 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Haplotypes |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D006801 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Humans |
| mesh[27].qualifier_ui | |
| mesh[27].descriptor_ui | D008297 |
| mesh[27].is_major_topic | False |
| mesh[27].qualifier_name | |
| mesh[27].descriptor_name | Male |
| mesh[28].qualifier_ui | Q000235 |
| mesh[28].descriptor_ui | D020641 |
| mesh[28].is_major_topic | False |
| mesh[28].qualifier_name | genetics |
| mesh[28].descriptor_name | Polymorphism, Single Nucleotide |
| mesh[29].qualifier_ui | Q000235 |
| mesh[29].descriptor_ui | D000071439 |
| mesh[29].is_major_topic | False |
| mesh[29].qualifier_name | genetics |
| mesh[29].descriptor_name | Pseudoautosomal Regions |
| mesh[30].qualifier_ui | Q000235 |
| mesh[30].descriptor_ui | D011995 |
| mesh[30].is_major_topic | False |
| mesh[30].qualifier_name | genetics |
| mesh[30].descriptor_name | Recombination, Genetic |
| mesh[31].qualifier_ui | Q000166 |
| mesh[31].descriptor_ui | D013094 |
| mesh[31].is_major_topic | False |
| mesh[31].qualifier_name | cytology |
| mesh[31].descriptor_name | Spermatozoa |
| type | article |
| title | Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis |
| biblio.issue | 10 |
| biblio.volume | 14 |
| biblio.last_page | e1007680 |
| biblio.first_page | e1007680 |
| topics[0].id | https://openalex.org/T11077 |
| topics[0].field.id | https://openalex.org/fields/13 |
| topics[0].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[0].score | 0.9994000196456909 |
| topics[0].domain.id | https://openalex.org/domains/1 |
| topics[0].domain.display_name | Life Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/1311 |
| topics[0].subfield.display_name | Genetics |
| topics[0].display_name | Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities |
| topics[1].id | https://openalex.org/T10434 |
| topics[1].field.id | https://openalex.org/fields/11 |
| topics[1].field.display_name | Agricultural and Biological Sciences |
| topics[1].score | 0.9993000030517578 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/1110 |
| topics[1].subfield.display_name | Plant Science |
| topics[1].display_name | Chromosomal and Genetic Variations |
| topics[2].id | https://openalex.org/T10222 |
| topics[2].field.id | https://openalex.org/fields/13 |
| topics[2].field.display_name | Biochemistry, Genetics and Molecular Biology |
| topics[2].score | 0.9955000281333923 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/1312 |
| topics[2].subfield.display_name | Molecular Biology |
| topics[2].display_name | Genomics and Chromatin Dynamics |
| is_xpac | False |
| apc_list.value | 2655 |
| apc_list.currency | USD |
| apc_list.value_usd | 2655 |
| apc_paid.value | 2655 |
| apc_paid.currency | USD |
| apc_paid.value_usd | 2655 |
| concepts[0].id | https://openalex.org/C169836425 |
| concepts[0].level | 4 |
| concepts[0].score | 0.9813204407691956 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q2115752 |
| concepts[0].display_name | Pseudoautosomal region |
| concepts[1].id | https://openalex.org/C86803240 |
| concepts[1].level | 0 |
| concepts[1].score | 0.8215399980545044 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q420 |
| concepts[1].display_name | Biology |
| concepts[2].id | https://openalex.org/C115220002 |
| concepts[2].level | 4 |
| concepts[2].score | 0.7146342396736145 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q244145 |
| concepts[2].display_name | Chromosomal crossover |
| concepts[3].id | https://openalex.org/C54355233 |
| concepts[3].level | 1 |
| concepts[3].score | 0.6856006979942322 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q7162 |
| concepts[3].display_name | Genetics |
| concepts[4].id | https://openalex.org/C148196450 |
| concepts[4].level | 3 |
| concepts[4].score | 0.6167750954627991 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q21100485 |
| concepts[4].display_name | Meiosis |
| concepts[5].id | https://openalex.org/C156695909 |
| concepts[5].level | 3 |
| concepts[5].score | 0.5795087218284607 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q3373825 |
| concepts[5].display_name | Recombination |
| concepts[6].id | https://openalex.org/C78458016 |
| concepts[6].level | 1 |
| concepts[6].score | 0.5763417482376099 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q840400 |
| concepts[6].display_name | Evolutionary biology |
| concepts[7].id | https://openalex.org/C2780246931 |
| concepts[7].level | 3 |
| concepts[7].score | 0.5630851984024048 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q202771 |
| concepts[7].display_name | Y chromosome |
| concepts[8].id | https://openalex.org/C112212490 |
| concepts[8].level | 4 |
| concepts[8].score | 0.5503631234169006 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q471134 |
| concepts[8].display_name | Gene conversion |
| concepts[9].id | https://openalex.org/C35158069 |
| concepts[9].level | 3 |
| concepts[9].score | 0.5253509879112244 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q61333 |
| concepts[9].display_name | X chromosome |
| concepts[10].id | https://openalex.org/C197754878 |
| concepts[10].level | 4 |
| concepts[10].score | 0.4844946563243866 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q80711 |
| concepts[10].display_name | Haplotype |
| concepts[11].id | https://openalex.org/C54809848 |
| concepts[11].level | 4 |
| concepts[11].score | 0.43340831995010376 |
| concepts[11].wikidata | https://www.wikidata.org/wiki/Q1918189 |
| concepts[11].display_name | Meiotic drive |
| concepts[12].id | https://openalex.org/C102744134 |
| concepts[12].level | 3 |
| concepts[12].score | 0.42485982179641724 |
| concepts[12].wikidata | https://www.wikidata.org/wiki/Q22280388 |
| concepts[12].display_name | Homologous recombination |
| concepts[13].id | https://openalex.org/C35605836 |
| concepts[13].level | 5 |
| concepts[13].score | 0.41765347123146057 |
| concepts[13].wikidata | https://www.wikidata.org/wiki/Q2064311 |
| concepts[13].display_name | Linkage disequilibrium |
| concepts[14].id | https://openalex.org/C30481170 |
| concepts[14].level | 3 |
| concepts[14].score | 0.4155849814414978 |
| concepts[14].wikidata | https://www.wikidata.org/wiki/Q37748 |
| concepts[14].display_name | Chromosome |
| concepts[15].id | https://openalex.org/C104317684 |
| concepts[15].level | 2 |
| concepts[15].score | 0.3099043071269989 |
| concepts[15].wikidata | https://www.wikidata.org/wiki/Q7187 |
| concepts[15].display_name | Gene |
| concepts[16].id | https://openalex.org/C180754005 |
| concepts[16].level | 3 |
| concepts[16].score | 0.17126277089118958 |
| concepts[16].wikidata | https://www.wikidata.org/wiki/Q80726 |
| concepts[16].display_name | Allele |
| keywords[0].id | https://openalex.org/keywords/pseudoautosomal-region |
| keywords[0].score | 0.9813204407691956 |
| keywords[0].display_name | Pseudoautosomal region |
| keywords[1].id | https://openalex.org/keywords/biology |
| keywords[1].score | 0.8215399980545044 |
| keywords[1].display_name | Biology |
| keywords[2].id | https://openalex.org/keywords/chromosomal-crossover |
| keywords[2].score | 0.7146342396736145 |
| keywords[2].display_name | Chromosomal crossover |
| keywords[3].id | https://openalex.org/keywords/genetics |
| keywords[3].score | 0.6856006979942322 |
| keywords[3].display_name | Genetics |
| keywords[4].id | https://openalex.org/keywords/meiosis |
| keywords[4].score | 0.6167750954627991 |
| keywords[4].display_name | Meiosis |
| keywords[5].id | https://openalex.org/keywords/recombination |
| keywords[5].score | 0.5795087218284607 |
| keywords[5].display_name | Recombination |
| keywords[6].id | https://openalex.org/keywords/evolutionary-biology |
| keywords[6].score | 0.5763417482376099 |
| keywords[6].display_name | Evolutionary biology |
| keywords[7].id | https://openalex.org/keywords/y-chromosome |
| keywords[7].score | 0.5630851984024048 |
| keywords[7].display_name | Y chromosome |
| keywords[8].id | https://openalex.org/keywords/gene-conversion |
| keywords[8].score | 0.5503631234169006 |
| keywords[8].display_name | Gene conversion |
| keywords[9].id | https://openalex.org/keywords/x-chromosome |
| keywords[9].score | 0.5253509879112244 |
| keywords[9].display_name | X chromosome |
| keywords[10].id | https://openalex.org/keywords/haplotype |
| keywords[10].score | 0.4844946563243866 |
| keywords[10].display_name | Haplotype |
| keywords[11].id | https://openalex.org/keywords/meiotic-drive |
| keywords[11].score | 0.43340831995010376 |
| keywords[11].display_name | Meiotic drive |
| keywords[12].id | https://openalex.org/keywords/homologous-recombination |
| keywords[12].score | 0.42485982179641724 |
| keywords[12].display_name | Homologous recombination |
| keywords[13].id | https://openalex.org/keywords/linkage-disequilibrium |
| keywords[13].score | 0.41765347123146057 |
| keywords[13].display_name | Linkage disequilibrium |
| keywords[14].id | https://openalex.org/keywords/chromosome |
| keywords[14].score | 0.4155849814414978 |
| keywords[14].display_name | Chromosome |
| keywords[15].id | https://openalex.org/keywords/gene |
| keywords[15].score | 0.3099043071269989 |
| keywords[15].display_name | Gene |
| keywords[16].id | https://openalex.org/keywords/allele |
| keywords[16].score | 0.17126277089118958 |
| keywords[16].display_name | Allele |
| language | en |
| locations[0].id | doi:10.1371/journal.pgen.1007680 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S103870658 |
| locations[0].source.issn | 1553-7390, 1553-7404 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 1553-7390 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | PLoS Genetics |
| locations[0].source.host_organization | https://openalex.org/P4310315706 |
| locations[0].source.host_organization_name | Public Library of Science |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310315706 |
| locations[0].source.host_organization_lineage_names | Public Library of Science |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printable |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | PLOS Genetics |
| locations[0].landing_page_url | https://doi.org/10.1371/journal.pgen.1007680 |
| locations[1].id | pmid:30296256 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | PLoS genetics |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/30296256 |
| locations[2].id | pmh:oai:doaj.org/article:d1da9ce8b4b54ceda4658e61ef43b1d5 |
| locations[2].is_oa | False |
| locations[2].source.id | https://openalex.org/S4306401280 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[2].source.host_organization | |
| locations[2].source.host_organization_name | |
| locations[2].license | |
| locations[2].pdf_url | |
| locations[2].version | publishedVersion |
| locations[2].raw_type | article |
| locations[2].license_id | |
| locations[2].is_accepted | True |
| locations[2].is_published | True |
| locations[2].raw_source_name | PLoS Genetics, Vol 14, Iss 10, p e1007680 (2018) |
| locations[2].landing_page_url | https://doaj.org/article/d1da9ce8b4b54ceda4658e61ef43b1d5 |
| locations[3].id | pmh:oai:europepmc.org:5162999 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306400806 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | Europe PMC (PubMed Central) |
| locations[3].source.host_organization | https://openalex.org/I1303153112 |
| locations[3].source.host_organization_name | European Bioinformatics Institute |
| locations[3].source.host_organization_lineage | https://openalex.org/I1303153112 |
| locations[3].license | cc-by |
| locations[3].pdf_url | |
| locations[3].version | publishedVersion |
| locations[3].raw_type | Text |
| locations[3].license_id | https://openalex.org/licenses/cc-by |
| locations[3].is_accepted | True |
| locations[3].is_published | True |
| locations[3].raw_source_name | |
| locations[3].landing_page_url | http://europepmc.org/pmc/articles/PMC6193736 |
| locations[4].id | pmh:oai:pubmedcentral.nih.gov:6193736 |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S2764455111 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | False |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | PubMed Central |
| locations[4].source.host_organization | https://openalex.org/I1299303238 |
| locations[4].source.host_organization_name | National Institutes of Health |
| locations[4].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[4].license | cc-by |
| locations[4].pdf_url | |
| locations[4].version | publishedVersion |
| locations[4].raw_type | Text |
| locations[4].license_id | https://openalex.org/licenses/cc-by |
| locations[4].is_accepted | True |
| locations[4].is_published | True |
| locations[4].raw_source_name | PLoS Genet |
| locations[4].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/6193736 |
| locations[5].id | pmh:oai:lirias2repo.kuleuven.be:123456789/627912 |
| locations[5].is_oa | False |
| locations[5].source.id | https://openalex.org/S4306401954 |
| locations[5].source.issn | |
| locations[5].source.type | repository |
| locations[5].source.is_oa | False |
| locations[5].source.issn_l | |
| locations[5].source.is_core | False |
| locations[5].source.is_in_doaj | False |
| locations[5].source.display_name | Lirias (KU Leuven) |
| locations[5].source.host_organization | https://openalex.org/I99464096 |
| locations[5].source.host_organization_name | KU Leuven |
| locations[5].source.host_organization_lineage | https://openalex.org/I99464096 |
| locations[5].license | |
| locations[5].pdf_url | |
| locations[5].version | acceptedVersion |
| locations[5].raw_type | info:eu-repo/semantics/article |
| locations[5].license_id | |
| locations[5].is_accepted | True |
| locations[5].is_published | False |
| locations[5].raw_source_name | |
| locations[5].landing_page_url | https://lirias.kuleuven.be/handle/123456789/627912 |
| locations[6].id | pmh:oai:figshare.com:article/7179062 |
| locations[6].is_oa | True |
| locations[6].source.id | https://openalex.org/S4306400572 |
| locations[6].source.issn | |
| locations[6].source.type | repository |
| locations[6].source.is_oa | False |
| locations[6].source.issn_l | |
| locations[6].source.is_core | False |
| locations[6].source.is_in_doaj | False |
| locations[6].source.display_name | OPAL (Open@LaTrobe) (La Trobe University) |
| locations[6].source.host_organization | https://openalex.org/I196829312 |
| locations[6].source.host_organization_name | La Trobe University |
| locations[6].source.host_organization_lineage | https://openalex.org/I196829312 |
| locations[6].license | cc-by |
| locations[6].pdf_url | |
| locations[6].version | submittedVersion |
| locations[6].raw_type | Dataset |
| locations[6].license_id | https://openalex.org/licenses/cc-by |
| locations[6].is_accepted | False |
| locations[6].is_published | False |
| locations[6].raw_source_name | |
| locations[6].landing_page_url | https://figshare.com/articles/dataset/Recombination_hotspots_in_an_extended_human_pseudoautosomal_domain_predicted_from_double-strand_break_maps_and_characterized_by_sperm-based_crossover_analysis/7179062 |
| locations[7].id | pmh:oai:lra.le.ac.uk:2381/45044 |
| locations[7].is_oa | True |
| locations[7].source.id | https://openalex.org/S4306402365 |
| locations[7].source.issn | |
| locations[7].source.type | repository |
| locations[7].source.is_oa | False |
| locations[7].source.issn_l | |
| locations[7].source.is_core | False |
| locations[7].source.is_in_doaj | False |
| locations[7].source.display_name | Leicester Research Archive (University of Leicester) |
| locations[7].source.host_organization | https://openalex.org/I153648349 |
| locations[7].source.host_organization_name | University of Leicester |
| locations[7].source.host_organization_lineage | https://openalex.org/I153648349 |
| locations[7].license | cc-by |
| locations[7].pdf_url | |
| locations[7].version | submittedVersion |
| locations[7].raw_type | Journal Article |
| locations[7].license_id | https://openalex.org/licenses/cc-by |
| locations[7].is_accepted | False |
| locations[7].is_published | False |
| locations[7].raw_source_name | |
| locations[7].landing_page_url | https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007680 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5000523872 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-2173-0008 |
| authorships[0].author.display_name | Nitikorn Poriswanish |
| authorships[0].countries | GB, TH |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I1332387789, https://openalex.org/I25399158 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Forensic Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand |
| authorships[0].affiliations[1].institution_ids | https://openalex.org/I153648349 |
| authorships[0].affiliations[1].raw_affiliation_string | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[0].institutions[0].id | https://openalex.org/I153648349 |
| authorships[0].institutions[0].ror | https://ror.org/04h699437 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I153648349 |
| authorships[0].institutions[0].country_code | GB |
| authorships[0].institutions[0].display_name | University of Leicester |
| authorships[0].institutions[1].id | https://openalex.org/I25399158 |
| authorships[0].institutions[1].ror | https://ror.org/01znkr924 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I25399158 |
| authorships[0].institutions[1].country_code | TH |
| authorships[0].institutions[1].display_name | Mahidol University |
| authorships[0].institutions[2].id | https://openalex.org/I1332387789 |
| authorships[0].institutions[2].ror | https://ror.org/0331zs648 |
| authorships[0].institutions[2].type | healthcare |
| authorships[0].institutions[2].lineage | https://openalex.org/I1332387789 |
| authorships[0].institutions[2].country_code | TH |
| authorships[0].institutions[2].display_name | Siriraj Hospital |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Nitikorn Poriswanish |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Department of Forensic Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[1].author.id | https://openalex.org/A5066558071 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-0971-438X |
| authorships[1].author.display_name | Rita Neumann |
| authorships[1].countries | GB |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I153648349 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[1].institutions[0].id | https://openalex.org/I153648349 |
| authorships[1].institutions[0].ror | https://ror.org/04h699437 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I153648349 |
| authorships[1].institutions[0].country_code | GB |
| authorships[1].institutions[0].display_name | University of Leicester |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Rita Neumann |
| authorships[1].is_corresponding | True |
| authorships[1].raw_affiliation_strings | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[2].author.id | https://openalex.org/A5007579161 |
| authorships[2].author.orcid | https://orcid.org/0000-0001-8337-4654 |
| authorships[2].author.display_name | Jon H. Wetton |
| authorships[2].countries | GB |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I153648349 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[2].institutions[0].id | https://openalex.org/I153648349 |
| authorships[2].institutions[0].ror | https://ror.org/04h699437 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I153648349 |
| authorships[2].institutions[0].country_code | GB |
| authorships[2].institutions[0].display_name | University of Leicester |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Jon H. Wetton |
| authorships[2].is_corresponding | True |
| authorships[2].raw_affiliation_strings | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[3].author.id | https://openalex.org/A5068760676 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-9745-2462 |
| authorships[3].author.display_name | J. Wagstaff |
| authorships[3].countries | GB |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I153648349 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[3].institutions[0].id | https://openalex.org/I153648349 |
| authorships[3].institutions[0].ror | https://ror.org/04h699437 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I153648349 |
| authorships[3].institutions[0].country_code | GB |
| authorships[3].institutions[0].display_name | University of Leicester |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | John Wagstaff |
| authorships[3].is_corresponding | True |
| authorships[3].raw_affiliation_strings | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[4].author.id | https://openalex.org/A5022327754 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-5974-7235 |
| authorships[4].author.display_name | Maarten Larmuseau |
| authorships[4].countries | BE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I99464096 |
| authorships[4].affiliations[0].raw_affiliation_string | Laboratory of Forensic Genetics and Molecular Archaeology, Department of Imaging and Pathology, KU Leuven, Belgium |
| authorships[4].institutions[0].id | https://openalex.org/I99464096 |
| authorships[4].institutions[0].ror | https://ror.org/05f950310 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I99464096 |
| authorships[4].institutions[0].country_code | BE |
| authorships[4].institutions[0].display_name | KU Leuven |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Maarten H. D. Larmuseau |
| authorships[4].is_corresponding | True |
| authorships[4].raw_affiliation_strings | Laboratory of Forensic Genetics and Molecular Archaeology, Department of Imaging and Pathology, KU Leuven, Belgium |
| authorships[5].author.id | https://openalex.org/A5084000812 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-8061-1308 |
| authorships[5].author.display_name | Mark A. Jobling |
| authorships[5].countries | GB |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I153648349 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[5].institutions[0].id | https://openalex.org/I153648349 |
| authorships[5].institutions[0].ror | https://ror.org/04h699437 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I153648349 |
| authorships[5].institutions[0].country_code | GB |
| authorships[5].institutions[0].display_name | University of Leicester |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Mark A. Jobling |
| authorships[5].is_corresponding | True |
| authorships[5].raw_affiliation_strings | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[6].author.id | https://openalex.org/A5030157714 |
| authorships[6].author.orcid | https://orcid.org/0000-0001-8541-2458 |
| authorships[6].author.display_name | Celia A. May |
| authorships[6].countries | GB |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I153648349 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| authorships[6].institutions[0].id | https://openalex.org/I153648349 |
| authorships[6].institutions[0].ror | https://ror.org/04h699437 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I153648349 |
| authorships[6].institutions[0].country_code | GB |
| authorships[6].institutions[0].display_name | University of Leicester |
| authorships[6].author_position | last |
| authorships[6].raw_author_name | Celia A. May |
| authorships[6].is_corresponding | True |
| authorships[6].raw_affiliation_strings | Department of Genetics & Genome Biology, University of Leicester, Leicester, United Kingdom |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printable |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11077 |
| primary_topic.field.id | https://openalex.org/fields/13 |
| primary_topic.field.display_name | Biochemistry, Genetics and Molecular Biology |
| primary_topic.score | 0.9994000196456909 |
| primary_topic.domain.id | https://openalex.org/domains/1 |
| primary_topic.domain.display_name | Life Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/1311 |
| primary_topic.subfield.display_name | Genetics |
| primary_topic.display_name | Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities |
| related_works | https://openalex.org/W1980853918, https://openalex.org/W2037107419, https://openalex.org/W2126675036, https://openalex.org/W2144686577, https://openalex.org/W2153145992, https://openalex.org/W1924069948, https://openalex.org/W2894919995, https://openalex.org/W1992249022, https://openalex.org/W1999583821, https://openalex.org/W2087850275 |
| cited_by_count | 10 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2022 |
| counts_by_year[1].cited_by_count | 2 |
| counts_by_year[2].year | 2021 |
| counts_by_year[2].cited_by_count | 1 |
| counts_by_year[3].year | 2020 |
| counts_by_year[3].cited_by_count | 3 |
| counts_by_year[4].year | 2019 |
| counts_by_year[4].cited_by_count | 3 |
| locations_count | 8 |
| best_oa_location.id | doi:10.1371/journal.pgen.1007680 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S103870658 |
| best_oa_location.source.issn | 1553-7390, 1553-7404 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 1553-7390 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | PLoS Genetics |
| best_oa_location.source.host_organization | https://openalex.org/P4310315706 |
| best_oa_location.source.host_organization_name | Public Library of Science |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310315706 |
| best_oa_location.source.host_organization_lineage_names | Public Library of Science |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printable |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | PLOS Genetics |
| best_oa_location.landing_page_url | https://doi.org/10.1371/journal.pgen.1007680 |
| primary_location.id | doi:10.1371/journal.pgen.1007680 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S103870658 |
| primary_location.source.issn | 1553-7390, 1553-7404 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 1553-7390 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | PLoS Genetics |
| primary_location.source.host_organization | https://openalex.org/P4310315706 |
| primary_location.source.host_organization_name | Public Library of Science |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310315706 |
| primary_location.source.host_organization_lineage_names | Public Library of Science |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1007680&type=printable |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | PLOS Genetics |
| primary_location.landing_page_url | https://doi.org/10.1371/journal.pgen.1007680 |
| publication_date | 2018-10-08 |
| publication_year | 2018 |
| referenced_works | https://openalex.org/W2025699653, https://openalex.org/W2053852336, https://openalex.org/W2003861119, https://openalex.org/W2010133343, https://openalex.org/W2030228799, https://openalex.org/W2074148774, https://openalex.org/W1518792000, https://openalex.org/W2089378812, https://openalex.org/W2156967983, https://openalex.org/W1980853918, https://openalex.org/W2137452657, https://openalex.org/W140634989, https://openalex.org/W2077811261, https://openalex.org/W2086448215, https://openalex.org/W2020958409, https://openalex.org/W1987093963, https://openalex.org/W2308736777, https://openalex.org/W1596459374, https://openalex.org/W1991867417, https://openalex.org/W2105184999, https://openalex.org/W2020260974, https://openalex.org/W1730861791, https://openalex.org/W1977090939, https://openalex.org/W2170284389, https://openalex.org/W2004691787, https://openalex.org/W1988896526, https://openalex.org/W2077357134, https://openalex.org/W2071936353, https://openalex.org/W2047657819, https://openalex.org/W1963756058, https://openalex.org/W2785258365, https://openalex.org/W2122732537, https://openalex.org/W2125685565, https://openalex.org/W2096791516, https://openalex.org/W2142781472, https://openalex.org/W2153145992, https://openalex.org/W2042497384, https://openalex.org/W2072688044, https://openalex.org/W2045601906, https://openalex.org/W2124429706, https://openalex.org/W2056954872, https://openalex.org/W2069681711, https://openalex.org/W1992249022, https://openalex.org/W1999583821, https://openalex.org/W2135267901, https://openalex.org/W2126084304, https://openalex.org/W2110755408, https://openalex.org/W2031082289, https://openalex.org/W2006852618, https://openalex.org/W1907733689, https://openalex.org/W1977212112, https://openalex.org/W2775759340, https://openalex.org/W2140470486, https://openalex.org/W1984921840, https://openalex.org/W2074678950, https://openalex.org/W2001341582, https://openalex.org/W1968557064, https://openalex.org/W1928207406, https://openalex.org/W2577550981, https://openalex.org/W2096991924, https://openalex.org/W2067007270, https://openalex.org/W2609468559, https://openalex.org/W2531301510, https://openalex.org/W2060234119, https://openalex.org/W2140798431, https://openalex.org/W2409856937, https://openalex.org/W2082704080, https://openalex.org/W2010933912, https://openalex.org/W2096420865, https://openalex.org/W2084407487, https://openalex.org/W2336048325, https://openalex.org/W2013550946, https://openalex.org/W2469018879 |
| referenced_works_count | 73 |
| abstract_inverted_index.1 | 23 |
| abstract_inverted_index.X | 2, 69, 151, 205 |
| abstract_inverted_index.Y | 4, 72, 158, 250, 256 |
| abstract_inverted_index.a | 10, 62, 162, 165, 266 |
| abstract_inverted_index.So | 90 |
| abstract_inverted_index.We | 187, 290 |
| abstract_inverted_index.an | 76 |
| abstract_inverted_index.as | 44, 209, 252 |
| abstract_inverted_index.at | 14, 84, 144, 161 |
| abstract_inverted_index.by | 110, 254 |
| abstract_inverted_index.in | 29, 87, 203, 225, 245 |
| abstract_inverted_index.is | 102, 220 |
| abstract_inverted_index.it | 48 |
| abstract_inverted_index.kb | 66 |
| abstract_inverted_index.of | 12, 17, 64, 113, 117, 128, 174, 180, 200, 207, 241, 248, 269, 276, 286, 301 |
| abstract_inverted_index.on | 125, 156 |
| abstract_inverted_index.to | 61, 70, 98, 141, 264, 296 |
| abstract_inverted_index.us | 263 |
| abstract_inverted_index.we | 106 |
| abstract_inverted_index.DNA | 39 |
| abstract_inverted_index.DSB | 194 |
| abstract_inverted_index.The | 0 |
| abstract_inverted_index.and | 3, 37, 152, 164, 183, 196, 228, 239, 258 |
| abstract_inverted_index.are | 6 |
| abstract_inverted_index.but | 8 |
| abstract_inverted_index.due | 60 |
| abstract_inverted_index.for | 121, 223 |
| abstract_inverted_index.has | 40, 82, 95 |
| abstract_inverted_index.may | 234 |
| abstract_inverted_index.the | 15, 33, 53, 68, 71, 126, 150, 153, 157, 169, 192, 204, 246, 249, 272, 297 |
| abstract_inverted_index.two | 118, 122 |
| abstract_inverted_index.was | 49, 147 |
| abstract_inverted_index.PAR1 | 78, 287 |
| abstract_inverted_index.This | 80 |
| abstract_inverted_index.also | 235 |
| abstract_inverted_index.been | 42, 96 |
| abstract_inverted_index.both | 160, 226, 255 |
| abstract_inverted_index.ePAR | 154, 242, 274, 292 |
| abstract_inverted_index.each | 116 |
| abstract_inverted_index.far, | 91 |
| abstract_inverted_index.from | 67, 115, 211 |
| abstract_inverted_index.gene | 185 |
| abstract_inverted_index.good | 189 |
| abstract_inverted_index.male | 30, 131, 193, 227 |
| abstract_inverted_index.men, | 120 |
| abstract_inverted_index.only | 92 |
| abstract_inverted_index.over | 271 |
| abstract_inverted_index.rate | 268 |
| abstract_inverted_index.seen | 143 |
| abstract_inverted_index.site | 167 |
| abstract_inverted_index.than | 279 |
| abstract_inverted_index.that | 25, 52, 74, 142, 217 |
| abstract_inverted_index.this | 100, 201, 215, 218 |
| abstract_inverted_index.tips | 16 |
| abstract_inverted_index.very | 293 |
| abstract_inverted_index.with | 283 |
| abstract_inverted_index.~110 | 65 |
| abstract_inverted_index.(DSB) | 136 |
| abstract_inverted_index.Here, | 105 |
| abstract_inverted_index.Other | 172 |
| abstract_inverted_index.PAR1. | 302 |
| abstract_inverted_index.among | 46, 57 |
| abstract_inverted_index.arms, | 20 |
| abstract_inverted_index.basis | 127 |
| abstract_inverted_index.borne | 155 |
| abstract_inverted_index.break | 135 |
| abstract_inverted_index.event | 81 |
| abstract_inverted_index.human | 1, 58, 88 |
| abstract_inverted_index.least | 85 |
| abstract_inverted_index.maps. | 137 |
| abstract_inverted_index.proof | 109 |
| abstract_inverted_index.share | 9 |
| abstract_inverted_index.short | 19 |
| abstract_inverted_index.their | 18 |
| abstract_inverted_index.twice | 86 |
| abstract_inverted_index.110-kb | 170 |
| abstract_inverted_index.6-fold | 277 |
| abstract_inverted_index.chosen | 124 |
| abstract_inverted_index.direct | 108 |
| abstract_inverted_index.distal | 163 |
| abstract_inverted_index.entire | 273 |
| abstract_inverted_index.exist. | 236 |
| abstract_inverted_index.female | 229 |
| abstract_inverted_index.genome | 280 |
| abstract_inverted_index.likely | 294 |
| abstract_inverted_index.males, | 59 |
| abstract_inverted_index.placed | 244 |
| abstract_inverted_index.primed | 222 |
| abstract_inverted_index.region | 11, 22, 202, 219, 275 |
| abstract_inverted_index.single | 259 |
| abstract_inverted_index.sought | 107 |
| abstract_inverted_index.varies | 56 |
| abstract_inverted_index.within | 168 |
| abstract_inverted_index.(PAR1), | 24 |
| abstract_inverted_index.(ePAR). | 79 |
| abstract_inverted_index.active. | 104 |
| abstract_inverted_index.allowed | 262 |
| abstract_inverted_index.between | 35, 149, 191 |
| abstract_inverted_index.classic | 175 |
| abstract_inverted_index.creates | 75 |
| abstract_inverted_index.gametes | 114 |
| abstract_inverted_index.greater | 278 |
| abstract_inverted_index.limited | 93 |
| abstract_inverted_index.linkage | 212 |
| abstract_inverted_index.meiotic | 133 |
| abstract_inverted_index.minimum | 267 |
| abstract_inverted_index.suggest | 99 |
| abstract_inverted_index.Although | 32 |
| abstract_inverted_index.activity | 139, 199, 288 |
| abstract_inverted_index.although | 231 |
| abstract_inverted_index.average, | 281 |
| abstract_inverted_index.boundary | 34, 54 |
| abstract_inverted_index.clusters | 195 |
| abstract_inverted_index.conclude | 291 |
| abstract_inverted_index.critical | 298 |
| abstract_inverted_index.estimate | 265 |
| abstract_inverted_index.evidence | 94, 179 |
| abstract_inverted_index.extended | 77 |
| abstract_inverted_index.females, | 208 |
| abstract_inverted_index.function | 300 |
| abstract_inverted_index.homology | 13 |
| abstract_inverted_index.hotspots | 146, 177 |
| abstract_inverted_index.included | 178 |
| abstract_inverted_index.meiosis. | 31 |
| abstract_inverted_index.obligate | 27 |
| abstract_inverted_index.observed | 148, 188 |
| abstract_inverted_index.occurred | 83 |
| abstract_inverted_index.pedigree | 284 |
| abstract_inverted_index.position | 55 |
| abstract_inverted_index.proximal | 166 |
| abstract_inverted_index.recently | 50 |
| abstract_inverted_index.regarded | 43 |
| abstract_inverted_index.suggests | 216 |
| abstract_inverted_index.supports | 26 |
| abstract_inverted_index.Crossover | 138 |
| abstract_inverted_index.Extensive | 237 |
| abstract_inverted_index.GC-biased | 184 |
| abstract_inverted_index.analysis; | 214 |
| abstract_inverted_index.autosomal | 145 |
| abstract_inverted_index.conserved | 45 |
| abstract_inverted_index.crossover | 28, 224, 270, 299 |
| abstract_inverted_index.estimates | 285 |
| abstract_inverted_index.examining | 111 |
| abstract_inverted_index.extension | 101 |
| abstract_inverted_index.framework | 247 |
| abstract_inverted_index.hallmarks | 173 |
| abstract_inverted_index.inference | 240 |
| abstract_inverted_index.phylogeny | 251 |
| abstract_inverted_index.presented | 97 |
| abstract_inverted_index.primates, | 47 |
| abstract_inverted_index.published | 130 |
| abstract_inverted_index.similarly | 221 |
| abstract_inverted_index.thousands | 112 |
| abstract_inverted_index.chromosome | 73, 159 |
| abstract_inverted_index.comparable | 140, 282 |
| abstract_inverted_index.discovered | 51 |
| abstract_inverted_index.distortion | 182 |
| abstract_inverted_index.evolution. | 89 |
| abstract_inverted_index.extension. | 171 |
| abstract_inverted_index.generally. | 289 |
| abstract_inverted_index.germlines, | 230 |
| abstract_inverted_index.historical | 197 |
| abstract_inverted_index.nucleotide | 260 |
| abstract_inverted_index.previously | 129 |
| abstract_inverted_index.subregions | 123 |
| abstract_inverted_index.ascertained | 210, 253 |
| abstract_inverted_index.chromosomes | 5, 206 |
| abstract_inverted_index.contributes | 295 |
| abstract_inverted_index.conversion. | 186 |
| abstract_inverted_index.differences | 233 |
| abstract_inverted_index.haplotypes, | 243 |
| abstract_inverted_index.resequencing | 238 |
| abstract_inverted_index.sex-specific | 38, 232 |
| abstract_inverted_index.transmission | 181 |
| abstract_inverted_index.X-chromosomal | 132 |
| abstract_inverted_index.double-strand | 134 |
| abstract_inverted_index.ePAR-carrying | 119 |
| abstract_inverted_index.heteromorphic | 7 |
| abstract_inverted_index.recombination | 176, 198 |
| abstract_inverted_index.traditionally | 41 |
| abstract_inverted_index.translocation | 63 |
| abstract_inverted_index.correspondence | 190 |
| abstract_inverted_index.disequilibrium | 213 |
| abstract_inverted_index.polymorphisms, | 261 |
| abstract_inverted_index.microsatellites | 257 |
| abstract_inverted_index.pseudoautosomal | 21, 36 |
| abstract_inverted_index.recombinationally | 103 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5007579161, https://openalex.org/A5084000812, https://openalex.org/A5000523872, https://openalex.org/A5022327754, https://openalex.org/A5066558071, https://openalex.org/A5030157714, https://openalex.org/A5068760676 |
| countries_distinct_count | 3 |
| institutions_distinct_count | 7 |
| corresponding_institution_ids | https://openalex.org/I1332387789, https://openalex.org/I153648349, https://openalex.org/I25399158, https://openalex.org/I99464096 |
| citation_normalized_percentile.value | 0.82466525 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |