Recommendations for COVID‐19 vaccination in people with rheumatic disease: Developed by the Singapore Chapter of Rheumatologists Article Swipe
Amelia Santosa
,
Chuanhui Xu
,
Thaschawee Arkachaisri
,
Kok Ooi Kong
,
Aisha Lateef
,
Tau Hong Lee
,
K H Leong
,
Andrea Hsiu Ling Low
,
Melonie K Sriranganathan
,
T. Tan
,
Gim Gee Teng
,
Bernard Yu‐Hor Thong
,
Warren Fong
,
Manjari Lahiri
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1111/1756-185x.14107
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1111/1756-185x.14107
Aim People with rheumatic diseases (PRD) remain vulnerable in the era of the COVID‐19 pandemic. We formulated recommendations to meet the urgent need for a consensus for vaccination against SARS‐CoV‐2 in PRD. Methods Systematic literature reviews were performed to evaluate: (a) outcomes in PRD with COVID‐19; (b) efficacy, immunogenicity and safety of COVID‐19 vaccination; and (c) published guidelines/recommendations for non‐live, non‐COVID‐19 vaccinations in PRD. Recommendations were formulated based on the evidence and expert opinion according to the Grading of Recommendations Assessment, Development and Evaluation methodology. Results The consensus comprises 2 overarching principles and 7 recommendations. Vaccination against SARS‐CoV‐2 in PRD should be aligned with prevailing national policy and should be individualized through shared decision between the healthcare provider and patient. We strongly recommend that eligible PRD and household contacts be vaccinated against SARS‐CoV‐2. We conditionally recommended that the COVID‐19 vaccine be administered during quiescent disease if possible. Immunomodulatory drugs, other than rituximab, can be continued alongside vaccination. We conditionally recommend that the COVID‐19 vaccine be administered prior to commencing rituximab if possible. For patients on rituximab, the vaccine should be administered a minimum of 6 months after the last dose and/or 4 weeks prior to the next dose of rituximab. Post‐vaccination antibody titers against SARS‐CoV‐2 need not be measured. Any of the approved COVID‐19 vaccines may be used, with no particular preference. Conclusion These recommendations provide guidance for COVID‐19 vaccination in PRD. Most recommendations in this consensus are conditional, reflecting a lack of evidence or low‐level evidence.
Related Topics
Concepts
Medicine
Vaccination
Rituximab
Coronavirus disease 2019 (COVID-19)
Immunogenicity
Pandemic
Family medicine
Disease
Immunology
Internal medicine
Infectious disease (medical specialty)
Antibody
Metadata
- Type
- review
- Language
- en
- Landing Page
- https://doi.org/10.1111/1756-185x.14107
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1756-185X.14107
- OA Status
- bronze
- Cited By
- 38
- References
- 34
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3160026234
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3160026234Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/1756-185x.14107Digital Object Identifier
- Title
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Recommendations for COVID‐19 vaccination in people with rheumatic disease: Developed by the Singapore Chapter of RheumatologistsWork title
- Type
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reviewOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-05-10Full publication date if available
- Authors
-
Amelia Santosa, Chuanhui Xu, Thaschawee Arkachaisri, Kok Ooi Kong, Aisha Lateef, Tau Hong Lee, K H Leong, Andrea Hsiu Ling Low, Melonie K Sriranganathan, T. Tan, Gim Gee Teng, Bernard Yu‐Hor Thong, Warren Fong, Manjari LahiriList of authors in order
- Landing page
-
https://doi.org/10.1111/1756-185x.14107Publisher landing page
- PDF URL
-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1756-185X.14107Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1756-185X.14107Direct OA link when available
- Concepts
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Medicine, Vaccination, Rituximab, Coronavirus disease 2019 (COVID-19), Immunogenicity, Pandemic, Family medicine, Disease, Immunology, Internal medicine, Infectious disease (medical specialty), AntibodyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
38Total citation count in OpenAlex
- Citations by year (recent)
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2024: 10, 2023: 10, 2022: 10, 2021: 8Per-year citation counts (last 5 years)
- References (count)
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34Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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