Recurrent Drug-Induced Hypersensitivity Syndrome Following Bortezomib for Multiple Myeloma Article Swipe
Related Concepts
Medicine
Bortezomib
Allopurinol
Multiple myeloma
Drug
Minocycline
Hypersensitivity reaction
Lenalidomide
Dapsone
Delayed hypersensitivity
Proteasome inhibitor
Pharmacology
Dermatology
Internal medicine
Immunology
Antibiotics
Microbiology
Antigen
Biology
Austin Ambur
,
Rajiv Nathoo
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.7759/cureus.20830
· OA: W4200462021
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.7759/cureus.20830
· OA: W4200462021
Drug-induced hypersensitivity syndrome is a rare, severe, and delayed hypersensitivity reaction that may occur with exposure to a number of medications. Typical implicated medications include aromatic anticonvulsants, sulfonamides, minocycline, dapsone, and allopurinol. Bortezomib is a proteasome inhibitor and has rarely been associated with cutaneous hypersensitivity reactions. We report a case of recurrent drug-induced hypersensitivity syndrome secondary to bortezomib in a patient with multiple myeloma. The aim of this article is to highlight a unique mediation that may cause drug-induced hypersensitivity syndrome and to emphasize the challenge of managing these patients long-term to prevent relapse of the syndrome.
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