Refined atrial fibrillation screening and cost-effectiveness in the German population Article Swipe
Renate B. Schnabel
,
Christopher Wallenhorst
,
Daniel Engler
,
Stefan Blankenberg
,
Norbert Pfeiffer
,
Ngoc Anh Spruenker
,
Matthias Buettner
,
Matthias Michal
,
Karl J. Lackner
,
Thomas Münzel
,
Philipp S. Wild
,
Carlos Martínez
,
Ben Freedman
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/heartjnl-2020-318882
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1136/heartjnl-2020-318882
Objective Little is known on optimal screening population for detecting new atrial fibrillation (AF) in the community. We describe characteristics and estimate cost-effectiveness for a single timepoint electrocardiographic screening. Methods We performed a 12-lead ECG in the German population-based Gutenberg Health Study between 2007 and 2012 (n=15 010), mean age 55±11 years, 51% men and collected more than 120 clinical and biomarker variables, including N-terminal pro B-type natriuretic peptide (Nt-proBNP), risk factors, disease symptoms and echocardiographic variables. Results Of 15 010 individuals, 466 (3.1%) had AF. New AF was found in 32 individuals, 0.2% of the total sample, 0.5% of individuals aged 65–74 years and predominantly men (86%). The classical risk factor burden was high in individuals with new AF. The median estimated stroke risk was 2.2%/year, while risk of developing heart failure was 21% over 10 years. In the 65–74 year age group, the cost per quality-adjusted life-year gained resulting from a single timepoint screening was €30 361. In simulations, the costs were highly sensitive to AF detection rates, proportion of treatment and type of oral anticoagulant. Prescreening by Nt-proBNP measurements was not cost-effective in the current setting. Conclusions In our middle-aged population cohort, we identified 0.2% new AF by single timepoint screening. There was a significant estimated risk of stroke and heart failure in these individuals. Cost-effectiveness for screening may be reached in individuals aged 65 years and older. The simple age cut-off is not improved by using Nt-proBNP as a biomarker to guide a screening programme.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1136/heartjnl-2020-318882
- https://heart.bmj.com/content/heartjnl/108/6/451.full.pdf
- OA Status
- hybrid
- Cited By
- 12
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3189899103
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W3189899103Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1136/heartjnl-2020-318882Digital Object Identifier
- Title
-
Refined atrial fibrillation screening and cost-effectiveness in the German populationWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-08-10Full publication date if available
- Authors
-
Renate B. Schnabel, Christopher Wallenhorst, Daniel Engler, Stefan Blankenberg, Norbert Pfeiffer, Ngoc Anh Spruenker, Matthias Buettner, Matthias Michal, Karl J. Lackner, Thomas Münzel, Philipp S. Wild, Carlos Martínez, Ben FreedmanList of authors in order
- Landing page
-
https://doi.org/10.1136/heartjnl-2020-318882Publisher landing page
- PDF URL
-
https://heart.bmj.com/content/heartjnl/108/6/451.full.pdfDirect link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
hybridOpen access status per OpenAlex
- OA URL
-
https://heart.bmj.com/content/heartjnl/108/6/451.full.pdfDirect OA link when available
- Concepts
-
Medicine, Atrial fibrillation, German, Population, German population, Cardiology, Internal medicine, Intensive care medicine, Environmental health, History, ArchaeologyTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
12Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 1, 2024: 4, 2023: 5, 2022: 1, 2021: 1Per-year citation counts (last 5 years)
- References (count)
-
36Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W3189899103 |
|---|---|
| doi | https://doi.org/10.1136/heartjnl-2020-318882 |
| ids.doi | https://doi.org/10.1136/heartjnl-2020-318882 |
| ids.mag | 3189899103 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/34376487 |
| ids.openalex | https://openalex.org/W3189899103 |
| fwci | 1.95183249 |
| mesh[0].qualifier_ui | |
| mesh[0].descriptor_ui | D000328 |
| mesh[0].is_major_topic | False |
| mesh[0].qualifier_name | |
| mesh[0].descriptor_name | Adult |
| mesh[1].qualifier_ui | |
| mesh[1].descriptor_ui | D000368 |
| mesh[1].is_major_topic | False |
| mesh[1].qualifier_name | |
| mesh[1].descriptor_name | Aged |
| mesh[2].qualifier_ui | Q000175 |
| mesh[2].descriptor_ui | D001281 |
| mesh[2].is_major_topic | True |
| mesh[2].qualifier_name | diagnosis |
| mesh[2].descriptor_name | Atrial Fibrillation |
| mesh[3].qualifier_ui | Q000453 |
| mesh[3].descriptor_ui | D001281 |
| mesh[3].is_major_topic | True |
| mesh[3].qualifier_name | epidemiology |
| mesh[3].descriptor_name | Atrial Fibrillation |
| mesh[4].qualifier_ui | |
| mesh[4].descriptor_ui | D015415 |
| mesh[4].is_major_topic | False |
| mesh[4].qualifier_name | |
| mesh[4].descriptor_name | Biomarkers |
| mesh[5].qualifier_ui | |
| mesh[5].descriptor_ui | D003362 |
| mesh[5].is_major_topic | False |
| mesh[5].qualifier_name | |
| mesh[5].descriptor_name | Cost-Benefit Analysis |
| mesh[6].qualifier_ui | |
| mesh[6].descriptor_ui | D005260 |
| mesh[6].is_major_topic | False |
| mesh[6].qualifier_name | |
| mesh[6].descriptor_name | Female |
| mesh[7].qualifier_ui | |
| mesh[7].descriptor_ui | D006333 |
| mesh[7].is_major_topic | True |
| mesh[7].qualifier_name | |
| mesh[7].descriptor_name | Heart Failure |
| mesh[8].qualifier_ui | |
| mesh[8].descriptor_ui | D006801 |
| mesh[8].is_major_topic | False |
| mesh[8].qualifier_name | |
| mesh[8].descriptor_name | Humans |
| mesh[9].qualifier_ui | |
| mesh[9].descriptor_ui | D008297 |
| mesh[9].is_major_topic | False |
| mesh[9].qualifier_name | |
| mesh[9].descriptor_name | Male |
| mesh[10].qualifier_ui | |
| mesh[10].descriptor_ui | D008875 |
| mesh[10].is_major_topic | False |
| mesh[10].qualifier_name | |
| mesh[10].descriptor_name | Middle Aged |
| mesh[11].qualifier_ui | |
| mesh[11].descriptor_ui | D020097 |
| mesh[11].is_major_topic | False |
| mesh[11].qualifier_name | |
| mesh[11].descriptor_name | Natriuretic Peptide, Brain |
| mesh[12].qualifier_ui | |
| mesh[12].descriptor_ui | D010446 |
| mesh[12].is_major_topic | False |
| mesh[12].qualifier_name | |
| mesh[12].descriptor_name | Peptide Fragments |
| mesh[13].qualifier_ui | Q000517 |
| mesh[13].descriptor_ui | D020521 |
| mesh[13].is_major_topic | True |
| mesh[13].qualifier_name | prevention & control |
| mesh[13].descriptor_name | Stroke |
| mesh[14].qualifier_ui | |
| mesh[14].descriptor_ui | D000328 |
| mesh[14].is_major_topic | False |
| mesh[14].qualifier_name | |
| mesh[14].descriptor_name | Adult |
| mesh[15].qualifier_ui | |
| mesh[15].descriptor_ui | D000368 |
| mesh[15].is_major_topic | False |
| mesh[15].qualifier_name | |
| mesh[15].descriptor_name | Aged |
| mesh[16].qualifier_ui | Q000175 |
| mesh[16].descriptor_ui | D001281 |
| mesh[16].is_major_topic | True |
| mesh[16].qualifier_name | diagnosis |
| mesh[16].descriptor_name | Atrial Fibrillation |
| mesh[17].qualifier_ui | Q000453 |
| mesh[17].descriptor_ui | D001281 |
| mesh[17].is_major_topic | True |
| mesh[17].qualifier_name | epidemiology |
| mesh[17].descriptor_name | Atrial Fibrillation |
| mesh[18].qualifier_ui | |
| mesh[18].descriptor_ui | D015415 |
| mesh[18].is_major_topic | False |
| mesh[18].qualifier_name | |
| mesh[18].descriptor_name | Biomarkers |
| mesh[19].qualifier_ui | |
| mesh[19].descriptor_ui | D003362 |
| mesh[19].is_major_topic | False |
| mesh[19].qualifier_name | |
| mesh[19].descriptor_name | Cost-Benefit Analysis |
| mesh[20].qualifier_ui | |
| mesh[20].descriptor_ui | D005260 |
| mesh[20].is_major_topic | False |
| mesh[20].qualifier_name | |
| mesh[20].descriptor_name | Female |
| mesh[21].qualifier_ui | |
| mesh[21].descriptor_ui | D006333 |
| mesh[21].is_major_topic | True |
| mesh[21].qualifier_name | |
| mesh[21].descriptor_name | Heart Failure |
| mesh[22].qualifier_ui | |
| mesh[22].descriptor_ui | D006801 |
| mesh[22].is_major_topic | False |
| mesh[22].qualifier_name | |
| mesh[22].descriptor_name | Humans |
| mesh[23].qualifier_ui | |
| mesh[23].descriptor_ui | D008297 |
| mesh[23].is_major_topic | False |
| mesh[23].qualifier_name | |
| mesh[23].descriptor_name | Male |
| mesh[24].qualifier_ui | |
| mesh[24].descriptor_ui | D008875 |
| mesh[24].is_major_topic | False |
| mesh[24].qualifier_name | |
| mesh[24].descriptor_name | Middle Aged |
| mesh[25].qualifier_ui | |
| mesh[25].descriptor_ui | D020097 |
| mesh[25].is_major_topic | False |
| mesh[25].qualifier_name | |
| mesh[25].descriptor_name | Natriuretic Peptide, Brain |
| mesh[26].qualifier_ui | |
| mesh[26].descriptor_ui | D010446 |
| mesh[26].is_major_topic | False |
| mesh[26].qualifier_name | |
| mesh[26].descriptor_name | Peptide Fragments |
| mesh[27].qualifier_ui | Q000517 |
| mesh[27].descriptor_ui | D020521 |
| mesh[27].is_major_topic | True |
| mesh[27].qualifier_name | prevention & control |
| mesh[27].descriptor_name | Stroke |
| type | article |
| title | Refined atrial fibrillation screening and cost-effectiveness in the German population |
| awards[0].id | https://openalex.org/G2634934472 |
| awards[0].funder_id | https://openalex.org/F4320321114 |
| awards[0].funder_award_id | BMBF 01EO1503 |
| awards[0].funder_display_name | Bundesministerium für Bildung und Forschung |
| awards[1].id | https://openalex.org/G6015547599 |
| awards[1].funder_id | https://openalex.org/F4320320300 |
| awards[1].funder_award_id | 648131 |
| awards[1].funder_display_name | European Commission |
| awards[2].id | https://openalex.org/G169986164 |
| awards[2].funder_id | https://openalex.org/F4320320300 |
| awards[2].funder_award_id | 847770 |
| awards[2].funder_display_name | European Commission |
| biblio.issue | 6 |
| biblio.volume | 108 |
| biblio.last_page | 457 |
| biblio.first_page | 451 |
| grants[0].funder | https://openalex.org/F4320320300 |
| grants[0].award_id | 648131 |
| grants[0].funder_display_name | European Commission |
| grants[1].funder | https://openalex.org/F4320320300 |
| grants[1].award_id | 847770 |
| grants[1].funder_display_name | European Commission |
| grants[2].funder | https://openalex.org/F4320321114 |
| grants[2].award_id | BMBF 01EO1503 |
| grants[2].funder_display_name | Bundesministerium für Bildung und Forschung |
| topics[0].id | https://openalex.org/T10065 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 0.9998999834060669 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2705 |
| topics[0].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[0].display_name | Atrial Fibrillation Management and Outcomes |
| topics[1].id | https://openalex.org/T10217 |
| topics[1].field.id | https://openalex.org/fields/27 |
| topics[1].field.display_name | Medicine |
| topics[1].score | 0.9884999990463257 |
| topics[1].domain.id | https://openalex.org/domains/4 |
| topics[1].domain.display_name | Health Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2705 |
| topics[1].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[1].display_name | Cardiac electrophysiology and arrhythmias |
| topics[2].id | https://openalex.org/T11217 |
| topics[2].field.id | https://openalex.org/fields/27 |
| topics[2].field.display_name | Medicine |
| topics[2].score | 0.9884999990463257 |
| topics[2].domain.id | https://openalex.org/domains/4 |
| topics[2].domain.display_name | Health Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2705 |
| topics[2].subfield.display_name | Cardiology and Cardiovascular Medicine |
| topics[2].display_name | Cardiac Arrhythmias and Treatments |
| funders[0].id | https://openalex.org/F4320320300 |
| funders[0].ror | https://ror.org/00k4n6c32 |
| funders[0].display_name | European Commission |
| funders[1].id | https://openalex.org/F4320321114 |
| funders[1].ror | https://ror.org/04pz7b180 |
| funders[1].display_name | Bundesministerium für Bildung und Forschung |
| is_xpac | False |
| apc_list | |
| apc_paid | |
| concepts[0].id | https://openalex.org/C71924100 |
| concepts[0].level | 0 |
| concepts[0].score | 0.9714587330818176 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[0].display_name | Medicine |
| concepts[1].id | https://openalex.org/C2779161974 |
| concepts[1].level | 2 |
| concepts[1].score | 0.850906491279602 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q815819 |
| concepts[1].display_name | Atrial fibrillation |
| concepts[2].id | https://openalex.org/C154775046 |
| concepts[2].level | 2 |
| concepts[2].score | 0.6205499768257141 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q188 |
| concepts[2].display_name | German |
| concepts[3].id | https://openalex.org/C2908647359 |
| concepts[3].level | 2 |
| concepts[3].score | 0.5083324313163757 |
| concepts[3].wikidata | https://www.wikidata.org/wiki/Q2625603 |
| concepts[3].display_name | Population |
| concepts[4].id | https://openalex.org/C2909167518 |
| concepts[4].level | 3 |
| concepts[4].score | 0.4948963522911072 |
| concepts[4].wikidata | https://www.wikidata.org/wiki/Q327213 |
| concepts[4].display_name | German population |
| concepts[5].id | https://openalex.org/C164705383 |
| concepts[5].level | 1 |
| concepts[5].score | 0.49139633774757385 |
| concepts[5].wikidata | https://www.wikidata.org/wiki/Q10379 |
| concepts[5].display_name | Cardiology |
| concepts[6].id | https://openalex.org/C126322002 |
| concepts[6].level | 1 |
| concepts[6].score | 0.42224615812301636 |
| concepts[6].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[6].display_name | Internal medicine |
| concepts[7].id | https://openalex.org/C177713679 |
| concepts[7].level | 1 |
| concepts[7].score | 0.4003733694553375 |
| concepts[7].wikidata | https://www.wikidata.org/wiki/Q679690 |
| concepts[7].display_name | Intensive care medicine |
| concepts[8].id | https://openalex.org/C99454951 |
| concepts[8].level | 1 |
| concepts[8].score | 0.10517024993896484 |
| concepts[8].wikidata | https://www.wikidata.org/wiki/Q932068 |
| concepts[8].display_name | Environmental health |
| concepts[9].id | https://openalex.org/C95457728 |
| concepts[9].level | 0 |
| concepts[9].score | 0.0 |
| concepts[9].wikidata | https://www.wikidata.org/wiki/Q309 |
| concepts[9].display_name | History |
| concepts[10].id | https://openalex.org/C166957645 |
| concepts[10].level | 1 |
| concepts[10].score | 0.0 |
| concepts[10].wikidata | https://www.wikidata.org/wiki/Q23498 |
| concepts[10].display_name | Archaeology |
| keywords[0].id | https://openalex.org/keywords/medicine |
| keywords[0].score | 0.9714587330818176 |
| keywords[0].display_name | Medicine |
| keywords[1].id | https://openalex.org/keywords/atrial-fibrillation |
| keywords[1].score | 0.850906491279602 |
| keywords[1].display_name | Atrial fibrillation |
| keywords[2].id | https://openalex.org/keywords/german |
| keywords[2].score | 0.6205499768257141 |
| keywords[2].display_name | German |
| keywords[3].id | https://openalex.org/keywords/population |
| keywords[3].score | 0.5083324313163757 |
| keywords[3].display_name | Population |
| keywords[4].id | https://openalex.org/keywords/german-population |
| keywords[4].score | 0.4948963522911072 |
| keywords[4].display_name | German population |
| keywords[5].id | https://openalex.org/keywords/cardiology |
| keywords[5].score | 0.49139633774757385 |
| keywords[5].display_name | Cardiology |
| keywords[6].id | https://openalex.org/keywords/internal-medicine |
| keywords[6].score | 0.42224615812301636 |
| keywords[6].display_name | Internal medicine |
| keywords[7].id | https://openalex.org/keywords/intensive-care-medicine |
| keywords[7].score | 0.4003733694553375 |
| keywords[7].display_name | Intensive care medicine |
| keywords[8].id | https://openalex.org/keywords/environmental-health |
| keywords[8].score | 0.10517024993896484 |
| keywords[8].display_name | Environmental health |
| language | en |
| locations[0].id | doi:10.1136/heartjnl-2020-318882 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S191565391 |
| locations[0].source.issn | 1355-6037, 1468-201X |
| locations[0].source.type | journal |
| locations[0].source.is_oa | False |
| locations[0].source.issn_l | 1355-6037 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | False |
| locations[0].source.display_name | Heart |
| locations[0].source.host_organization | https://openalex.org/P4310319945 |
| locations[0].source.host_organization_name | BMJ |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310319945 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://heart.bmj.com/content/heartjnl/108/6/451.full.pdf |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Heart |
| locations[0].landing_page_url | https://doi.org/10.1136/heartjnl-2020-318882 |
| locations[1].id | pmid:34376487 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Heart (British Cardiac Society) |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/34376487 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:8899485 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Heart |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/8899485 |
| indexed_in | crossref, pubmed |
| authorships[0].author.id | https://openalex.org/A5090270823 |
| authorships[0].author.orcid | https://orcid.org/0000-0001-7170-9509 |
| authorships[0].author.display_name | Renate B. Schnabel |
| authorships[0].countries | DE |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| authorships[0].affiliations[0].raw_affiliation_string | Cardiology, University Heart Center Hamburg, Hamburg 52 20246, Germany |
| authorships[0].institutions[0].id | https://openalex.org/I4210108711 |
| authorships[0].institutions[0].ror | https://ror.org/01zgy1s35 |
| authorships[0].institutions[0].type | healthcare |
| authorships[0].institutions[0].lineage | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| authorships[0].institutions[0].country_code | DE |
| authorships[0].institutions[0].display_name | University Medical Center Hamburg-Eppendorf |
| authorships[0].institutions[1].id | https://openalex.org/I159176309 |
| authorships[0].institutions[1].ror | https://ror.org/00g30e956 |
| authorships[0].institutions[1].type | education |
| authorships[0].institutions[1].lineage | https://openalex.org/I159176309 |
| authorships[0].institutions[1].country_code | DE |
| authorships[0].institutions[1].display_name | Universität Hamburg |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Renate B Schnabel |
| authorships[0].is_corresponding | True |
| authorships[0].raw_affiliation_strings | Cardiology, University Heart Center Hamburg, Hamburg 52 20246, Germany |
| authorships[1].author.id | https://openalex.org/A5088335104 |
| authorships[1].author.orcid | https://orcid.org/0000-0001-7944-7347 |
| authorships[1].author.display_name | Christopher Wallenhorst |
| authorships[1].affiliations[0].raw_affiliation_string | Institute for Epidemiology, Statistics and Informatics GmbH, Frankfurt, Germany |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Christopher Wallenhorst |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Institute for Epidemiology, Statistics and Informatics GmbH, Frankfurt, Germany |
| authorships[2].author.id | https://openalex.org/A5010362031 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-9519-6258 |
| authorships[2].author.display_name | Daniel Engler |
| authorships[2].countries | DE |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I4210125971 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Cardiology, Universitäres Herzzentrum Hamburg (UHZ), Hamburg, Germany |
| authorships[2].institutions[0].id | https://openalex.org/I4210125971 |
| authorships[2].institutions[0].ror | https://ror.org/02nyezm25 |
| authorships[2].institutions[0].type | healthcare |
| authorships[2].institutions[0].lineage | https://openalex.org/I4210125971 |
| authorships[2].institutions[0].country_code | DE |
| authorships[2].institutions[0].display_name | Mammazentrum Hamburg |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Daniel Engler |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Cardiology, Universitäres Herzzentrum Hamburg (UHZ), Hamburg, Germany |
| authorships[3].author.id | https://openalex.org/A5030454575 |
| authorships[3].author.orcid | https://orcid.org/0000-0001-6488-2362 |
| authorships[3].author.display_name | Stefan Blankenberg |
| authorships[3].countries | DE |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| authorships[3].affiliations[0].raw_affiliation_string | Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany |
| authorships[3].institutions[0].id | https://openalex.org/I4210108711 |
| authorships[3].institutions[0].ror | https://ror.org/01zgy1s35 |
| authorships[3].institutions[0].type | healthcare |
| authorships[3].institutions[0].lineage | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| authorships[3].institutions[0].country_code | DE |
| authorships[3].institutions[0].display_name | University Medical Center Hamburg-Eppendorf |
| authorships[3].institutions[1].id | https://openalex.org/I159176309 |
| authorships[3].institutions[1].ror | https://ror.org/00g30e956 |
| authorships[3].institutions[1].type | education |
| authorships[3].institutions[1].lineage | https://openalex.org/I159176309 |
| authorships[3].institutions[1].country_code | DE |
| authorships[3].institutions[1].display_name | Universität Hamburg |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Stefan Blankenberg |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany |
| authorships[4].author.id | https://openalex.org/A5079455074 |
| authorships[4].author.orcid | https://orcid.org/0000-0002-5766-2617 |
| authorships[4].author.display_name | Norbert Pfeiffer |
| authorships[4].countries | DE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I197323543, https://openalex.org/I4210094062 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany |
| authorships[4].institutions[0].id | https://openalex.org/I197323543 |
| authorships[4].institutions[0].ror | https://ror.org/023b0x485 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I197323543 |
| authorships[4].institutions[0].country_code | DE |
| authorships[4].institutions[0].display_name | Johannes Gutenberg University Mainz |
| authorships[4].institutions[1].id | https://openalex.org/I4210094062 |
| authorships[4].institutions[1].ror | https://ror.org/00q1fsf04 |
| authorships[4].institutions[1].type | healthcare |
| authorships[4].institutions[1].lineage | https://openalex.org/I4210094062 |
| authorships[4].institutions[1].country_code | DE |
| authorships[4].institutions[1].display_name | University Medical Center of the Johannes Gutenberg University Mainz |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Norbert Pfeiffer |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany |
| authorships[5].author.id | https://openalex.org/A5071377618 |
| authorships[5].author.orcid | |
| authorships[5].author.display_name | Ngoc Anh Spruenker |
| authorships[5].countries | DE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I4210108711 |
| authorships[5].affiliations[0].raw_affiliation_string | University Heart and Vascular Center Hamburg Eppendorf, Hamburg, Germany |
| authorships[5].institutions[0].id | https://openalex.org/I4210108711 |
| authorships[5].institutions[0].ror | https://ror.org/01zgy1s35 |
| authorships[5].institutions[0].type | healthcare |
| authorships[5].institutions[0].lineage | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| authorships[5].institutions[0].country_code | DE |
| authorships[5].institutions[0].display_name | University Medical Center Hamburg-Eppendorf |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Ngoc Anh Spruenker |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | University Heart and Vascular Center Hamburg Eppendorf, Hamburg, Germany |
| authorships[6].author.id | https://openalex.org/A5072493706 |
| authorships[6].author.orcid | |
| authorships[6].author.display_name | Matthias Buettner |
| authorships[6].countries | DE |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I197323543, https://openalex.org/I4210094062 |
| authorships[6].affiliations[0].raw_affiliation_string | Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany |
| authorships[6].institutions[0].id | https://openalex.org/I197323543 |
| authorships[6].institutions[0].ror | https://ror.org/023b0x485 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I197323543 |
| authorships[6].institutions[0].country_code | DE |
| authorships[6].institutions[0].display_name | Johannes Gutenberg University Mainz |
| authorships[6].institutions[1].id | https://openalex.org/I4210094062 |
| authorships[6].institutions[1].ror | https://ror.org/00q1fsf04 |
| authorships[6].institutions[1].type | healthcare |
| authorships[6].institutions[1].lineage | https://openalex.org/I4210094062 |
| authorships[6].institutions[1].country_code | DE |
| authorships[6].institutions[1].display_name | University Medical Center of the Johannes Gutenberg University Mainz |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Matthias Buettner |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany |
| authorships[7].author.id | https://openalex.org/A5022275113 |
| authorships[7].author.orcid | https://orcid.org/0000-0002-4028-5851 |
| authorships[7].author.display_name | Matthias Michal |
| authorships[7].countries | DE |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I159176309, https://openalex.org/I197323543, https://openalex.org/I4210094062, https://openalex.org/I4210108711 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Hamburg, Germany |
| authorships[7].institutions[0].id | https://openalex.org/I197323543 |
| authorships[7].institutions[0].ror | https://ror.org/023b0x485 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I197323543 |
| authorships[7].institutions[0].country_code | DE |
| authorships[7].institutions[0].display_name | Johannes Gutenberg University Mainz |
| authorships[7].institutions[1].id | https://openalex.org/I4210108711 |
| authorships[7].institutions[1].ror | https://ror.org/01zgy1s35 |
| authorships[7].institutions[1].type | healthcare |
| authorships[7].institutions[1].lineage | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| authorships[7].institutions[1].country_code | DE |
| authorships[7].institutions[1].display_name | University Medical Center Hamburg-Eppendorf |
| authorships[7].institutions[2].id | https://openalex.org/I4210094062 |
| authorships[7].institutions[2].ror | https://ror.org/00q1fsf04 |
| authorships[7].institutions[2].type | healthcare |
| authorships[7].institutions[2].lineage | https://openalex.org/I4210094062 |
| authorships[7].institutions[2].country_code | DE |
| authorships[7].institutions[2].display_name | University Medical Center of the Johannes Gutenberg University Mainz |
| authorships[7].institutions[3].id | https://openalex.org/I159176309 |
| authorships[7].institutions[3].ror | https://ror.org/00g30e956 |
| authorships[7].institutions[3].type | education |
| authorships[7].institutions[3].lineage | https://openalex.org/I159176309 |
| authorships[7].institutions[3].country_code | DE |
| authorships[7].institutions[3].display_name | Universität Hamburg |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Matthias Michal |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Hamburg, Germany |
| authorships[8].author.id | https://openalex.org/A5075174977 |
| authorships[8].author.orcid | https://orcid.org/0000-0002-1985-7931 |
| authorships[8].author.display_name | Karl J. Lackner |
| authorships[8].countries | DE |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I197323543, https://openalex.org/I4210094062 |
| authorships[8].affiliations[0].raw_affiliation_string | Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany |
| authorships[8].institutions[0].id | https://openalex.org/I197323543 |
| authorships[8].institutions[0].ror | https://ror.org/023b0x485 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I197323543 |
| authorships[8].institutions[0].country_code | DE |
| authorships[8].institutions[0].display_name | Johannes Gutenberg University Mainz |
| authorships[8].institutions[1].id | https://openalex.org/I4210094062 |
| authorships[8].institutions[1].ror | https://ror.org/00q1fsf04 |
| authorships[8].institutions[1].type | healthcare |
| authorships[8].institutions[1].lineage | https://openalex.org/I4210094062 |
| authorships[8].institutions[1].country_code | DE |
| authorships[8].institutions[1].display_name | University Medical Center of the Johannes Gutenberg University Mainz |
| authorships[8].author_position | middle |
| authorships[8].raw_author_name | Karl J Lackner |
| authorships[8].is_corresponding | False |
| authorships[8].raw_affiliation_strings | Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany |
| authorships[9].author.id | https://openalex.org/A5113521673 |
| authorships[9].author.orcid | |
| authorships[9].author.display_name | Thomas Münzel |
| authorships[9].countries | DE |
| authorships[9].affiliations[0].institution_ids | https://openalex.org/I197323543, https://openalex.org/I4210094062 |
| authorships[9].affiliations[0].raw_affiliation_string | Department of Medicine 2, University Medical Center Mainz, Mainz, Germany |
| authorships[9].institutions[0].id | https://openalex.org/I197323543 |
| authorships[9].institutions[0].ror | https://ror.org/023b0x485 |
| authorships[9].institutions[0].type | education |
| authorships[9].institutions[0].lineage | https://openalex.org/I197323543 |
| authorships[9].institutions[0].country_code | DE |
| authorships[9].institutions[0].display_name | Johannes Gutenberg University Mainz |
| authorships[9].institutions[1].id | https://openalex.org/I4210094062 |
| authorships[9].institutions[1].ror | https://ror.org/00q1fsf04 |
| authorships[9].institutions[1].type | healthcare |
| authorships[9].institutions[1].lineage | https://openalex.org/I4210094062 |
| authorships[9].institutions[1].country_code | DE |
| authorships[9].institutions[1].display_name | University Medical Center of the Johannes Gutenberg University Mainz |
| authorships[9].author_position | middle |
| authorships[9].raw_author_name | Thomas Münzel |
| authorships[9].is_corresponding | False |
| authorships[9].raw_affiliation_strings | Department of Medicine 2, University Medical Center Mainz, Mainz, Germany |
| authorships[10].author.id | https://openalex.org/A5022358930 |
| authorships[10].author.orcid | https://orcid.org/0000-0003-4413-9752 |
| authorships[10].author.display_name | Philipp S. Wild |
| authorships[10].countries | DE |
| authorships[10].affiliations[0].institution_ids | https://openalex.org/I197323543, https://openalex.org/I4210094062 |
| authorships[10].affiliations[0].raw_affiliation_string | Department of Preventive Cardiology and Preventive Medicine, University Medical Center Mainz, Mainz, Rhineland-Palatinate, Germany |
| authorships[10].institutions[0].id | https://openalex.org/I197323543 |
| authorships[10].institutions[0].ror | https://ror.org/023b0x485 |
| authorships[10].institutions[0].type | education |
| authorships[10].institutions[0].lineage | https://openalex.org/I197323543 |
| authorships[10].institutions[0].country_code | DE |
| authorships[10].institutions[0].display_name | Johannes Gutenberg University Mainz |
| authorships[10].institutions[1].id | https://openalex.org/I4210094062 |
| authorships[10].institutions[1].ror | https://ror.org/00q1fsf04 |
| authorships[10].institutions[1].type | healthcare |
| authorships[10].institutions[1].lineage | https://openalex.org/I4210094062 |
| authorships[10].institutions[1].country_code | DE |
| authorships[10].institutions[1].display_name | University Medical Center of the Johannes Gutenberg University Mainz |
| authorships[10].author_position | middle |
| authorships[10].raw_author_name | Philipp S Wild |
| authorships[10].is_corresponding | False |
| authorships[10].raw_affiliation_strings | Department of Preventive Cardiology and Preventive Medicine, University Medical Center Mainz, Mainz, Rhineland-Palatinate, Germany |
| authorships[11].author.id | https://openalex.org/A5107924007 |
| authorships[11].author.orcid | https://orcid.org/0000-0001-6498-6428 |
| authorships[11].author.display_name | Carlos Martínez |
| authorships[11].affiliations[0].raw_affiliation_string | Institute for Epidemiology, Statistics and Informatics GmbH, Frankfurt, Germany |
| authorships[11].author_position | middle |
| authorships[11].raw_author_name | Carlos Martinez |
| authorships[11].is_corresponding | False |
| authorships[11].raw_affiliation_strings | Institute for Epidemiology, Statistics and Informatics GmbH, Frankfurt, Germany |
| authorships[12].author.id | https://openalex.org/A5005536581 |
| authorships[12].author.orcid | https://orcid.org/0000-0002-3809-2911 |
| authorships[12].author.display_name | Ben Freedman |
| authorships[12].countries | AU |
| authorships[12].affiliations[0].institution_ids | https://openalex.org/I129604602, https://openalex.org/I2801241159 |
| authorships[12].affiliations[0].raw_affiliation_string | University of Sydney, Charles Perkins Centre, Heart Research Institute, Sydney, New South Wales, Australia |
| authorships[12].institutions[0].id | https://openalex.org/I2801241159 |
| authorships[12].institutions[0].ror | https://ror.org/046fa4y88 |
| authorships[12].institutions[0].type | facility |
| authorships[12].institutions[0].lineage | https://openalex.org/I2801241159 |
| authorships[12].institutions[0].country_code | AU |
| authorships[12].institutions[0].display_name | The Heart Research Institute |
| authorships[12].institutions[1].id | https://openalex.org/I129604602 |
| authorships[12].institutions[1].ror | https://ror.org/0384j8v12 |
| authorships[12].institutions[1].type | education |
| authorships[12].institutions[1].lineage | https://openalex.org/I129604602 |
| authorships[12].institutions[1].country_code | AU |
| authorships[12].institutions[1].display_name | The University of Sydney |
| authorships[12].author_position | last |
| authorships[12].raw_author_name | Ben Freedman |
| authorships[12].is_corresponding | False |
| authorships[12].raw_affiliation_strings | University of Sydney, Charles Perkins Centre, Heart Research Institute, Sydney, New South Wales, Australia |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://heart.bmj.com/content/heartjnl/108/6/451.full.pdf |
| open_access.oa_status | hybrid |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Refined atrial fibrillation screening and cost-effectiveness in the German population |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T10065 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 0.9998999834060669 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2705 |
| primary_topic.subfield.display_name | Cardiology and Cardiovascular Medicine |
| primary_topic.display_name | Atrial Fibrillation Management and Outcomes |
| related_works | https://openalex.org/W3173606202, https://openalex.org/W1531601525, https://openalex.org/W4243875435, https://openalex.org/W74487859, https://openalex.org/W1959882930, https://openalex.org/W2522151558, https://openalex.org/W2257555832, https://openalex.org/W958282391, https://openalex.org/W2915137319, https://openalex.org/W2918114199 |
| cited_by_count | 12 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 1 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 4 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 5 |
| counts_by_year[3].year | 2022 |
| counts_by_year[3].cited_by_count | 1 |
| counts_by_year[4].year | 2021 |
| counts_by_year[4].cited_by_count | 1 |
| locations_count | 3 |
| best_oa_location.id | doi:10.1136/heartjnl-2020-318882 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S191565391 |
| best_oa_location.source.issn | 1355-6037, 1468-201X |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | False |
| best_oa_location.source.issn_l | 1355-6037 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | False |
| best_oa_location.source.display_name | Heart |
| best_oa_location.source.host_organization | https://openalex.org/P4310319945 |
| best_oa_location.source.host_organization_name | BMJ |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310319945 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://heart.bmj.com/content/heartjnl/108/6/451.full.pdf |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Heart |
| best_oa_location.landing_page_url | https://doi.org/10.1136/heartjnl-2020-318882 |
| primary_location.id | doi:10.1136/heartjnl-2020-318882 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S191565391 |
| primary_location.source.issn | 1355-6037, 1468-201X |
| primary_location.source.type | journal |
| primary_location.source.is_oa | False |
| primary_location.source.issn_l | 1355-6037 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | False |
| primary_location.source.display_name | Heart |
| primary_location.source.host_organization | https://openalex.org/P4310319945 |
| primary_location.source.host_organization_name | BMJ |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310319945 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://heart.bmj.com/content/heartjnl/108/6/451.full.pdf |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Heart |
| primary_location.landing_page_url | https://doi.org/10.1136/heartjnl-2020-318882 |
| publication_date | 2021-08-10 |
| publication_year | 2021 |
| referenced_works | https://openalex.org/W2147018083, https://openalex.org/W2947446138, https://openalex.org/W2020061893, https://openalex.org/W2055181085, https://openalex.org/W1616073113, https://openalex.org/W2971768162, https://openalex.org/W9727340, https://openalex.org/W2164861810, https://openalex.org/W1747765887, https://openalex.org/W2097173178, https://openalex.org/W2097360283, https://openalex.org/W1992944164, https://openalex.org/W2032388524, https://openalex.org/W4294541781, https://openalex.org/W4324114579, https://openalex.org/W2089485949, https://openalex.org/W1998083759, https://openalex.org/W3107986792, https://openalex.org/W3082188176, https://openalex.org/W2092165341, https://openalex.org/W2566015711, https://openalex.org/W2020682484, https://openalex.org/W2025221952, https://openalex.org/W2260482868, https://openalex.org/W2726718945, https://openalex.org/W2308510141, https://openalex.org/W2889260593, https://openalex.org/W2909002141, https://openalex.org/W2987985090, https://openalex.org/W1985320908, https://openalex.org/W3216808633, https://openalex.org/W2157076315, https://openalex.org/W2099919979, https://openalex.org/W108653819, https://openalex.org/W2149457559, https://openalex.org/W4237409336 |
| referenced_works_count | 36 |
| abstract_inverted_index.a | 24, 32, 152, 206, 242, 246 |
| abstract_inverted_index.10 | 136 |
| abstract_inverted_index.15 | 79 |
| abstract_inverted_index.32 | 91 |
| abstract_inverted_index.65 | 227 |
| abstract_inverted_index.AF | 87, 167, 199 |
| abstract_inverted_index.In | 138, 159, 190 |
| abstract_inverted_index.Of | 78 |
| abstract_inverted_index.We | 17, 30 |
| abstract_inverted_index.as | 241 |
| abstract_inverted_index.be | 222 |
| abstract_inverted_index.by | 179, 200, 238 |
| abstract_inverted_index.in | 14, 35, 90, 115, 185, 215, 224 |
| abstract_inverted_index.is | 2, 235 |
| abstract_inverted_index.of | 94, 99, 129, 171, 175, 210 |
| abstract_inverted_index.on | 4 |
| abstract_inverted_index.to | 166, 244 |
| abstract_inverted_index.we | 195 |
| abstract_inverted_index.010 | 80 |
| abstract_inverted_index.120 | 58 |
| abstract_inverted_index.21% | 134 |
| abstract_inverted_index.466 | 82 |
| abstract_inverted_index.51% | 52 |
| abstract_inverted_index.AF. | 85, 119 |
| abstract_inverted_index.ECG | 34 |
| abstract_inverted_index.New | 86 |
| abstract_inverted_index.The | 108, 120, 231 |
| abstract_inverted_index.age | 49, 142, 233 |
| abstract_inverted_index.and | 20, 44, 54, 60, 74, 104, 173, 212, 229 |
| abstract_inverted_index.for | 8, 23, 219 |
| abstract_inverted_index.had | 84 |
| abstract_inverted_index.may | 221 |
| abstract_inverted_index.men | 53, 106 |
| abstract_inverted_index.new | 10, 118, 198 |
| abstract_inverted_index.not | 183, 236 |
| abstract_inverted_index.our | 191 |
| abstract_inverted_index.per | 146 |
| abstract_inverted_index.pro | 65 |
| abstract_inverted_index.the | 15, 36, 95, 139, 144, 161, 186 |
| abstract_inverted_index.was | 88, 113, 125, 133, 156, 182, 205 |
| abstract_inverted_index.(AF) | 13 |
| abstract_inverted_index.0.2% | 93, 197 |
| abstract_inverted_index.0.5% | 98 |
| abstract_inverted_index.2007 | 43 |
| abstract_inverted_index.2012 | 45 |
| abstract_inverted_index.361. | 158 |
| abstract_inverted_index.aged | 101, 226 |
| abstract_inverted_index.cost | 145 |
| abstract_inverted_index.from | 151 |
| abstract_inverted_index.high | 114 |
| abstract_inverted_index.mean | 48 |
| abstract_inverted_index.more | 56 |
| abstract_inverted_index.oral | 176 |
| abstract_inverted_index.over | 135 |
| abstract_inverted_index.risk | 70, 110, 124, 128, 209 |
| abstract_inverted_index.than | 57 |
| abstract_inverted_index.type | 174 |
| abstract_inverted_index.were | 163 |
| abstract_inverted_index.with | 117 |
| abstract_inverted_index.year | 141 |
| abstract_inverted_index.(n=15 | 46 |
| abstract_inverted_index.010), | 47 |
| abstract_inverted_index.Study | 41 |
| abstract_inverted_index.There | 204 |
| abstract_inverted_index.costs | 162 |
| abstract_inverted_index.found | 89 |
| abstract_inverted_index.guide | 245 |
| abstract_inverted_index.heart | 131, 213 |
| abstract_inverted_index.known | 3 |
| abstract_inverted_index.these | 216 |
| abstract_inverted_index.total | 96 |
| abstract_inverted_index.using | 239 |
| abstract_inverted_index.while | 127 |
| abstract_inverted_index.years | 103, 228 |
| abstract_inverted_index.€30 | 157 |
| abstract_inverted_index.(3.1%) | 83 |
| abstract_inverted_index.(86%). | 107 |
| abstract_inverted_index.55±11 | 50 |
| abstract_inverted_index.B-type | 66 |
| abstract_inverted_index.German | 37 |
| abstract_inverted_index.Health | 40 |
| abstract_inverted_index.Little | 1 |
| abstract_inverted_index.atrial | 11 |
| abstract_inverted_index.burden | 112 |
| abstract_inverted_index.factor | 111 |
| abstract_inverted_index.gained | 149 |
| abstract_inverted_index.group, | 143 |
| abstract_inverted_index.highly | 164 |
| abstract_inverted_index.median | 121 |
| abstract_inverted_index.older. | 230 |
| abstract_inverted_index.rates, | 169 |
| abstract_inverted_index.simple | 232 |
| abstract_inverted_index.single | 25, 153, 201 |
| abstract_inverted_index.stroke | 123, 211 |
| abstract_inverted_index.years, | 51 |
| abstract_inverted_index.years. | 137 |
| abstract_inverted_index.12-lead | 33 |
| abstract_inverted_index.65–74 | 102, 140 |
| abstract_inverted_index.Methods | 29 |
| abstract_inverted_index.Results | 77 |
| abstract_inverted_index.between | 42 |
| abstract_inverted_index.cohort, | 194 |
| abstract_inverted_index.current | 187 |
| abstract_inverted_index.cut-off | 234 |
| abstract_inverted_index.disease | 72 |
| abstract_inverted_index.failure | 132, 214 |
| abstract_inverted_index.optimal | 5 |
| abstract_inverted_index.peptide | 68 |
| abstract_inverted_index.reached | 223 |
| abstract_inverted_index.sample, | 97 |
| abstract_inverted_index.clinical | 59 |
| abstract_inverted_index.describe | 18 |
| abstract_inverted_index.estimate | 21 |
| abstract_inverted_index.factors, | 71 |
| abstract_inverted_index.improved | 237 |
| abstract_inverted_index.setting. | 188 |
| abstract_inverted_index.symptoms | 73 |
| abstract_inverted_index.Gutenberg | 39 |
| abstract_inverted_index.Nt-proBNP | 180, 240 |
| abstract_inverted_index.Objective | 0 |
| abstract_inverted_index.biomarker | 61, 243 |
| abstract_inverted_index.classical | 109 |
| abstract_inverted_index.collected | 55 |
| abstract_inverted_index.detecting | 9 |
| abstract_inverted_index.detection | 168 |
| abstract_inverted_index.estimated | 122, 208 |
| abstract_inverted_index.including | 63 |
| abstract_inverted_index.life-year | 148 |
| abstract_inverted_index.performed | 31 |
| abstract_inverted_index.resulting | 150 |
| abstract_inverted_index.screening | 6, 155, 220, 247 |
| abstract_inverted_index.sensitive | 165 |
| abstract_inverted_index.timepoint | 26, 154, 202 |
| abstract_inverted_index.treatment | 172 |
| abstract_inverted_index.2.2%/year, | 126 |
| abstract_inverted_index.N-terminal | 64 |
| abstract_inverted_index.community. | 16 |
| abstract_inverted_index.developing | 130 |
| abstract_inverted_index.identified | 196 |
| abstract_inverted_index.population | 7, 193 |
| abstract_inverted_index.programme. | 248 |
| abstract_inverted_index.proportion | 170 |
| abstract_inverted_index.screening. | 28, 203 |
| abstract_inverted_index.variables, | 62 |
| abstract_inverted_index.variables. | 76 |
| abstract_inverted_index.Conclusions | 189 |
| abstract_inverted_index.individuals | 100, 116, 225 |
| abstract_inverted_index.middle-aged | 192 |
| abstract_inverted_index.natriuretic | 67 |
| abstract_inverted_index.significant | 207 |
| abstract_inverted_index.(Nt-proBNP), | 69 |
| abstract_inverted_index.Prescreening | 178 |
| abstract_inverted_index.fibrillation | 12 |
| abstract_inverted_index.individuals, | 81, 92 |
| abstract_inverted_index.individuals. | 217 |
| abstract_inverted_index.measurements | 181 |
| abstract_inverted_index.simulations, | 160 |
| abstract_inverted_index.predominantly | 105 |
| abstract_inverted_index.anticoagulant. | 177 |
| abstract_inverted_index.cost-effective | 184 |
| abstract_inverted_index.characteristics | 19 |
| abstract_inverted_index.population-based | 38 |
| abstract_inverted_index.quality-adjusted | 147 |
| abstract_inverted_index.echocardiographic | 75 |
| abstract_inverted_index.Cost-effectiveness | 218 |
| abstract_inverted_index.cost-effectiveness | 22 |
| abstract_inverted_index.electrocardiographic | 27 |
| cited_by_percentile_year.max | 98 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5090270823 |
| countries_distinct_count | 2 |
| institutions_distinct_count | 13 |
| corresponding_institution_ids | https://openalex.org/I159176309, https://openalex.org/I4210108711 |
| citation_normalized_percentile.value | 0.86065167 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |