Relationship between Occupational Metal Exposure and Hypertension Risk Based on Conditional Logistic Regression Analysis Article Swipe
YOU?
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· 2022
· Open Access
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· DOI: https://doi.org/10.3390/metabo12121259
Occupational exposure is a significant source of metal contact; previous studies have been limited regarding the effect of occupational metal exposure on the development of hypertension. This study was conducted to assess the levels of exposure of certain metals (chromium (Cr), iron (Fe), manganese (Mn), and nickel (Ni)) in hypertensive and non-hypertensive workers and to assess the relationship between the risk of hypertension and metal exposure level. Our study included 138 hypertensive patients as case groups and 138 non-hypertensive participants as controls. The exposure risk level was divided according to the limit value after collecting and testing the metal dust in the workshop. Considering the influence of single- and poly-metal, single factor analysis and conditional logistic regression analysis of poly-metal were carried out. The results of the model indicated that the incidence of hypertension increased with an increase in Cr exposure level, and the risk of hypertension was 1.85 times higher in the highest exposure than in the lowest exposure (95% CI: 1.20–2.86, p < 0.05). Mn has the same effect as Cr. There was no significant correlation between Fe or Ni and hypertension. Our findings suggested that Cr and Mn exposure in the work environment might increase the risk of hypertension, while no effect of Fe and Ni on blood pressure was found. Prospective study designs in larger populations are needed to confirm our findings.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/metabo12121259
- https://www.mdpi.com/2218-1989/12/12/1259/pdf?version=1671010335
- OA Status
- gold
- Cited By
- 10
- References
- 36
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4311493312
Raw OpenAlex JSON
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https://openalex.org/W4311493312Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/metabo12121259Digital Object Identifier
- Title
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Relationship between Occupational Metal Exposure and Hypertension Risk Based on Conditional Logistic Regression AnalysisWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-12-14Full publication date if available
- Authors
-
Huiling Qian, Guangming Li, Yongbin Luo, Xiaolei Fu, Siyu Wan, Xiaoli Mao, Wenjun Yin, Zhiteng Min, Jinfeng Jiang, Guilin Yi, Xiaodong TanList of authors in order
- Landing page
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https://doi.org/10.3390/metabo12121259Publisher landing page
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https://www.mdpi.com/2218-1989/12/12/1259/pdf?version=1671010335Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2218-1989/12/12/1259/pdf?version=1671010335Direct OA link when available
- Concepts
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Logistic regression, Conditional logistic regression, Medicine, Statistics, Environmental health, Internal medicine, Mathematics, Odds ratioTop concepts (fields/topics) attached by OpenAlex
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10Total citation count in OpenAlex
- Citations by year (recent)
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2025: 6, 2024: 3, 2023: 1Per-year citation counts (last 5 years)
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36Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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