Renal transplantation outcomes in obese patients: a French cohort-based study Article Swipe
Yohann Foucher
,
Marine Lorent
,
Laetitia Albano
,
Sandrine Roux
,
Vincent Pernin
,
Moglie Le Quintrec
,
Christophe Legendre
,
Fanny Buron
,
Emmanuel Morélon
,
Sophie Girerd
,
Marc Ladrière
,
Denis Glotz
,
Carmen Lefaucher
,
Clarisse Kerleau
,
Jacques Dantal
,
Julien Branchereau
,
Magali Giral
·
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1186/s12882-021-02278-1
YOU?
·
· 2021
· Open Access
·
· DOI: https://doi.org/10.1186/s12882-021-02278-1
Background Whilst there are a number of publications comparing the relationship between body mass index (BMI) of kidney transplant recipients and graft/patient survival, no study has assessed this for a French patient cohort. Methods In this study, cause-specific Cox models were used to study patient and graft survival and several other time-to-event measures. Logistic regressions were performed to study surgical complications at 30 days post-transplantation as well as delayed graft function. Results Among the 4691 included patients, 747 patients were considered obese with a BMI level greater than 30 kg/m 2 . We observed a higher mortality for obese recipients (HR = 1.37, p = 0.0086) and higher risks of serious bacterial infections (HR = 1.24, p = 0.0006) and cardiac complications (HR = 1.45, p < 0.0001). We observed a trend towards death censored graft survival (HR = 1.22, p = 0.0666) and no significant increased risk of early surgical complications. Conclusions We showed that obesity increased the risk of death and serious bacterial infections and cardiac complications in obese French kidney transplant recipients. Further epidemiologic studies aiming to compare obese recipients versus obese candidates remaining on dialysis are needed to improve the guidelines for obese patient transplant allocation.
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Metadata
- Type
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- Language
- en
- Landing Page
- https://doi.org/10.1186/s12882-021-02278-1
- https://bmcnephrol.biomedcentral.com/counter/pdf/10.1186/s12882-021-02278-1
- OA Status
- gold
- Cited By
- 22
- References
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- Related Works
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- OpenAlex ID
- https://openalex.org/W3135476567
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3135476567Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.1186/s12882-021-02278-1Digital Object Identifier
- Title
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Renal transplantation outcomes in obese patients: a French cohort-based studyWork title
- Type
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articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2021Year of publication
- Publication date
-
2021-03-05Full publication date if available
- Authors
-
Yohann Foucher, Marine Lorent, Laetitia Albano, Sandrine Roux, Vincent Pernin, Moglie Le Quintrec, Christophe Legendre, Fanny Buron, Emmanuel Morélon, Sophie Girerd, Marc Ladrière, Denis Glotz, Carmen Lefaucher, Clarisse Kerleau, Jacques Dantal, Julien Branchereau, Magali GiralList of authors in order
- Landing page
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https://doi.org/10.1186/s12882-021-02278-1Publisher landing page
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-
https://bmcnephrol.biomedcentral.com/counter/pdf/10.1186/s12882-021-02278-1Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
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https://bmcnephrol.biomedcentral.com/counter/pdf/10.1186/s12882-021-02278-1Direct OA link when available
- Concepts
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Medicine, Nephrology, Internal medicine, Transplantation, Cohort study, Cohort, Kidney transplantation, Obesity, Intensive care medicineTop concepts (fields/topics) attached by OpenAlex
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22Total citation count in OpenAlex
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2025: 3, 2024: 8, 2023: 6, 2022: 4, 2021: 1Per-year citation counts (last 5 years)
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34Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| cited_by_percentile_year.min | 89 |
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