Research Progress in the Separation of Chemical Components from Essential Oils by High-Speed Countercurrent Chromatography Article Swipe
Linhong He
,
Zihao Zhong
,
Lijuan Zhang
,
Xi Bai
·
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/separations11050152
YOU?
·
· 2024
· Open Access
·
· DOI: https://doi.org/10.3390/separations11050152
Essential oils (EOs) are vital secondary metabolites in plants. They have garnered substantial attention owing to their distinct flavors and desirable attributes, including potent antioxidant, antibacterial, and antitumor properties. Nevertheless, the active constituents of EOs exhibit intricate chemical structures, and conventional separation techniques are inadequate for purifying the individual chemical components from EOs. High-speed countercurrent chromatography, based on the principles of a hydrodynamic equilibrium system, has emerged as a liquid–liquid chromatographic separation method renowned for its ability to handle substantial single injection volumes and the absence of irreversible adsorption. Consequently, in recent years, this technique has been widely employed in the isolation and refinement of natural products. In this review, a comprehensive analysis is conducted, contrasting the merits and demerits of high-speed countercurrent chromatography with conventional separation methods. The solvent systems, elution modes, commonly employed detectors, and practical applications are reviewed in the context of high-speed countercurrent chromatography for essential oil separation and purification. Furthermore, this review offers a glimpse into the potential prospects of applying this technique, with the intention of serving as a valuable reference for the use of high-speed countercurrent chromatography in the purification of EOs.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/separations11050152
- https://www.mdpi.com/2297-8739/11/5/152/pdf?version=1715762102
- OA Status
- gold
- Cited By
- 3
- References
- 73
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4396924306
All OpenAlex metadata
Raw OpenAlex JSON
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https://openalex.org/W4396924306Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.3390/separations11050152Digital Object Identifier
- Title
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Research Progress in the Separation of Chemical Components from Essential Oils by High-Speed Countercurrent ChromatographyWork title
- Type
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articleOpenAlex work type
- Language
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enPrimary language
- Publication year
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2024Year of publication
- Publication date
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2024-05-15Full publication date if available
- Authors
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Linhong He, Zihao Zhong, Lijuan Zhang, Xi BaiList of authors in order
- Landing page
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https://doi.org/10.3390/separations11050152Publisher landing page
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https://www.mdpi.com/2297-8739/11/5/152/pdf?version=1715762102Direct link to full text PDF
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YesWhether a free full text is available
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goldOpen access status per OpenAlex
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https://www.mdpi.com/2297-8739/11/5/152/pdf?version=1715762102Direct OA link when available
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Countercurrent chromatography, Countercurrent exchange, Chromatography, Countercurrent distribution, Separation (statistics), Chemistry, Chromatographic separation, High-performance liquid chromatography, Biology, Computer science, Anatomy, Machine learningTop concepts (fields/topics) attached by OpenAlex
- Cited by
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3Total citation count in OpenAlex
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2025: 2, 2024: 1Per-year citation counts (last 5 years)
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73Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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