RETRACTED: Two new coordination polymers: Magnetic properties and treatment activity on non-small cell lung cancer by reversing the resistance of the cancer cells Article Swipe
Yilong Wan
,
Yunyun Xu
,
Bo Peng
,
Lingdi Zhao
,
Quanli Gao
,
Dong Jiang
·
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1016/j.arabjc.2020.102921
YOU?
·
· 2020
· Open Access
·
· DOI: https://doi.org/10.1016/j.arabjc.2020.102921
In the current study, by employing 5-((4-carboxypyridin-2-yl)amino)isophthalic acid (H3L), a semirigid carboxylate-pyridine ligand with V-shape, two new transition metal coordination polymers with the chemical formulae of [Cu1.5(L)(H2O)]·2H2O (1) and [Co4(L)2(CH3CN)(OH)2(H2O)4]·3H2O (2) have been successfully prepared through the reaction between the H3L ligand and corresponding metal salts under the solvothermal reaction conditions. Magnetic investigations have suggested that there is antiferromagnetic coupling between neighboring metal ions in the two compounds. The application values of compounds 1 and 2 on the non-small cell lung cancer (NSCLC) was evaluated and the related mechanism was discussed at the same time. First of all, the Cell Counting Kit-8 (CCK-8) detection kit was performed to measure the viability of the non-small cell lung cancer cells after compound treatment. In addition to this, the real time reverse transcription polymerase chain reaction (real time RT-PCR) was used to detect the relative expression levels of the ezh2 gene in NSCLC cells after indicated treatment.
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1016/j.arabjc.2020.102921
- OA Status
- gold
- Cited By
- 2
- References
- 25
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W3106787615
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W3106787615Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1016/j.arabjc.2020.102921Digital Object Identifier
- Title
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RETRACTED: Two new coordination polymers: Magnetic properties and treatment activity on non-small cell lung cancer by reversing the resistance of the cancer cellsWork title
- Type
-
articleOpenAlex work type
- Language
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enPrimary language
- Publication year
-
2020Year of publication
- Publication date
-
2020-12-04Full publication date if available
- Authors
-
Yilong Wan, Yunyun Xu, Bo Peng, Lingdi Zhao, Quanli Gao, Dong JiangList of authors in order
- Landing page
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https://doi.org/10.1016/j.arabjc.2020.102921Publisher landing page
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YesWhether a free full text is available
- OA status
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goldOpen access status per OpenAlex
- OA URL
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https://doi.org/10.1016/j.arabjc.2020.102921Direct OA link when available
- Concepts
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Chemistry, Isophthalic acid, Pyridine, Lung cancer, Ligand (biochemistry), Viability assay, Metal ions in aqueous solution, Metal, Cell, Stereochemistry, Polymer chemistry, Receptor, Medicinal chemistry, Biochemistry, Oncology, Organic chemistry, Polyester, Terephthalic acid, MedicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
2Total citation count in OpenAlex
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2023: 1, 2022: 1Per-year citation counts (last 5 years)
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10Other works algorithmically related by OpenAlex
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