Review of Pharmacological Activity of Ephedra Gerardiana Article Swipe
YOU?
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· 2023
· Open Access
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· DOI: https://doi.org/10.32350/sir.72.05
Ephedra gerardiana (E. gerardiana,), commonly known as "Ma-huang," is a medicinal plant native to the Himalayan region. Historically, it has a long traditional use in various indigenous systems for medicinal purpose. The current review aims to summarize the present knowledge on the botanical description, phytochemistry, traditional uses, and pharmacological properties of E. gerardiana. This study was thoroughly based on previous literature and was conducted by using electronic databases such as PubMed, Scopus, and Google Scholar. Relevant studies and recently published articles up till 2020 were included in this review. E. gerardiana is a small shrub-like plant characterized by jointed stems, scale-like leaves, and cylindrical cones. It belongs to the family Ephedraceae and is commonly found in arid and semi-arid regions. Phytochemical analysis has revealed the presence of various bioactive compounds in Ephedra gerardiana, including ephedrine, pseudoephedrine, norephedrine, and methyl ephedrine. These alkaloids are primarily responsible for their pharmacological activities. In traditional medicine, Ephedra gerardiana has been used for its bronchodilatory, diaphoretic, diuretic, and thermogenic properties. Additionally, it has been employed for the treatment of respiratory disorders, namely, asthma and nasal congestion, as a stimulant. Its bioactive alkaloids, particularly ephedrine, have been extensively studied for their potential therapeutic applications. However, caution should be exercised due to the potential side effects associated with ephedrine-containing products. Further research can explore its mechanisms of action, optimize dosage regimens, and investigate potential drug interactions to ensure its safe and effective use in clinical settings.
Related Topics
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.32350/sir.72.05
- https://journals.umt.edu.pk/index.php/SIR/article/download/2980/1729
- OA Status
- diamond
- Cited By
- 4
- References
- 33
- Related Works
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- OpenAlex ID
- https://openalex.org/W4383107296
Raw OpenAlex JSON
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https://openalex.org/W4383107296Canonical identifier for this work in OpenAlex
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https://doi.org/10.32350/sir.72.05Digital Object Identifier
- Title
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Review of Pharmacological Activity of Ephedra GerardianaWork title
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articleOpenAlex work type
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enPrimary language
- Publication year
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2023Year of publication
- Publication date
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2023-06-15Full publication date if available
- Authors
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Halima Nazar, Azalfa Amar, Mohmmad Younus, Ghazala Shaheen, Hafiz Muhammad Asif, Farah Zafar, Sultan AyazList of authors in order
- Landing page
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https://doi.org/10.32350/sir.72.05Publisher landing page
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https://journals.umt.edu.pk/index.php/SIR/article/download/2980/1729Direct link to full text PDF
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YesWhether a free full text is available
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diamondOpen access status per OpenAlex
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https://journals.umt.edu.pk/index.php/SIR/article/download/2980/1729Direct OA link when available
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Traditional medicine, Siddha, Phytochemical, Medicine, PharmacologyTop concepts (fields/topics) attached by OpenAlex
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4Total citation count in OpenAlex
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2025: 4Per-year citation counts (last 5 years)
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33Number of works referenced by this work
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10Other works algorithmically related by OpenAlex
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| abstract_inverted_index.action, | 220 |
| abstract_inverted_index.belongs | 106 |
| abstract_inverted_index.caution | 199 |
| abstract_inverted_index.current | 32 |
| abstract_inverted_index.effects | 208 |
| abstract_inverted_index.explore | 216 |
| abstract_inverted_index.jointed | 98 |
| abstract_inverted_index.leaves, | 101 |
| abstract_inverted_index.namely, | 176 |
| abstract_inverted_index.present | 38 |
| abstract_inverted_index.region. | 16 |
| abstract_inverted_index.review. | 88 |
| abstract_inverted_index.studied | 192 |
| abstract_inverted_index.studies | 76 |
| abstract_inverted_index.systems | 27 |
| abstract_inverted_index.various | 25, 127 |
| abstract_inverted_index.However, | 198 |
| abstract_inverted_index.Relevant | 75 |
| abstract_inverted_index.Scholar. | 74 |
| abstract_inverted_index.analysis | 121 |
| abstract_inverted_index.articles | 80 |
| abstract_inverted_index.clinical | 237 |
| abstract_inverted_index.commonly | 4, 113 |
| abstract_inverted_index.employed | 169 |
| abstract_inverted_index.included | 85 |
| abstract_inverted_index.optimize | 221 |
| abstract_inverted_index.presence | 125 |
| abstract_inverted_index.previous | 59 |
| abstract_inverted_index.purpose. | 30 |
| abstract_inverted_index.recently | 78 |
| abstract_inverted_index.regions. | 119 |
| abstract_inverted_index.research | 214 |
| abstract_inverted_index.revealed | 123 |
| abstract_inverted_index.Himalayan | 15 |
| abstract_inverted_index.alkaloids | 141 |
| abstract_inverted_index.bioactive | 128, 185 |
| abstract_inverted_index.botanical | 42 |
| abstract_inverted_index.compounds | 129 |
| abstract_inverted_index.conducted | 63 |
| abstract_inverted_index.databases | 67 |
| abstract_inverted_index.diuretic, | 161 |
| abstract_inverted_index.effective | 234 |
| abstract_inverted_index.exercised | 202 |
| abstract_inverted_index.including | 133 |
| abstract_inverted_index.knowledge | 39 |
| abstract_inverted_index.medicinal | 10, 29 |
| abstract_inverted_index.medicine, | 151 |
| abstract_inverted_index.potential | 195, 206, 226 |
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| abstract_inverted_index.products. | 212 |
| abstract_inverted_index.published | 79 |
| abstract_inverted_index.regimens, | 223 |
| abstract_inverted_index.semi-arid | 118 |
| abstract_inverted_index.summarize | 36 |
| abstract_inverted_index.treatment | 172 |
| abstract_inverted_index.alkaloids, | 186 |
| abstract_inverted_index.associated | 209 |
| abstract_inverted_index.disorders, | 175 |
| abstract_inverted_index.electronic | 66 |
| abstract_inverted_index.ephedrine, | 134, 188 |
| abstract_inverted_index.ephedrine. | 139 |
| abstract_inverted_index.gerardiana | 1, 90, 153 |
| abstract_inverted_index.indigenous | 26 |
| abstract_inverted_index.literature | 60 |
| abstract_inverted_index.mechanisms | 218 |
| abstract_inverted_index.properties | 49 |
| abstract_inverted_index.scale-like | 100 |
| abstract_inverted_index.shrub-like | 94 |
| abstract_inverted_index.stimulant. | 183 |
| abstract_inverted_index.thoroughly | 56 |
| abstract_inverted_index."Ma-huang," | 7 |
| abstract_inverted_index.Ephedraceae | 110 |
| abstract_inverted_index.activities. | 148 |
| abstract_inverted_index.congestion, | 180 |
| abstract_inverted_index.cylindrical | 103 |
| abstract_inverted_index.extensively | 191 |
| abstract_inverted_index.gerardiana, | 132 |
| abstract_inverted_index.gerardiana. | 52 |
| abstract_inverted_index.investigate | 225 |
| abstract_inverted_index.properties. | 164 |
| abstract_inverted_index.respiratory | 174 |
| abstract_inverted_index.responsible | 144 |
| abstract_inverted_index.therapeutic | 196 |
| abstract_inverted_index.thermogenic | 163 |
| abstract_inverted_index.traditional | 22, 45, 150 |
| abstract_inverted_index.description, | 43 |
| abstract_inverted_index.diaphoretic, | 160 |
| abstract_inverted_index.interactions | 228 |
| abstract_inverted_index.particularly | 187 |
| abstract_inverted_index.Additionally, | 165 |
| abstract_inverted_index.Historically, | 17 |
| abstract_inverted_index.Phytochemical | 120 |
| abstract_inverted_index.applications. | 197 |
| abstract_inverted_index.characterized | 96 |
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| abstract_inverted_index.norephedrine, | 136 |
| abstract_inverted_index.pharmacological | 48, 147 |
| abstract_inverted_index.phytochemistry, | 44 |
| abstract_inverted_index.settings.
 | 238 |
| abstract_inverted_index.bronchodilatory, | 159 |
| abstract_inverted_index.pseudoephedrine, | 135 |
| abstract_inverted_index.ephedrine-containing | 211 |
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| cited_by_percentile_year.min | 97 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 7 |
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