RNA silencing of GM-CSF in CAR-T cells reduces the secretion of multiple inflammatory cytokines Article Swipe

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Siqi Shang , Yunshuo Chen , Xuejiao Yang , Ying Yang , Wenbo Wang , Yueying Wang ·

YOU? · · 2023 · Open Access · · DOI: https://doi.org/10.1007/s10637-023-01344-9

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Chimeric antigen receptor Proinflammatory cytokine Gene silencing Cytokine Immunotherapy Gene knockdown Small hairpin RNA Immunology Cancer research Secretion Cytokine release syndrome Biology Medicine Inflammation Cell culture Immune system Gene Endocrinology Genetics Biochemistry

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Type: article
Language: en
Landing Page: https://doi.org/10.1007/s10637-023-01344-9
PDF: https://link.springer.com/content/pdf/10.1007/s10637-023-01344-9.pdf
OA Status: bronze
Cited By: 6
References: 19
Related Works: 10
OpenAlex ID: https://openalex.org/W4361285193

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OpenAlex ID: https://openalex.org/W4361285193

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DOI: https://doi.org/10.1007/s10637-023-01344-9

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Title: RNA silencing of GM-CSF in CAR-T cells reduces the secretion of multiple inflammatory cytokines

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Type: article

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Language: en

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Publication year: 2023

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Publication date: 2023-03-29

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Authors: Siqi Shang, Yunshuo Chen, Xuejiao Yang, Ying Yang, Wenbo Wang, Yueying Wang

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Landing page: https://doi.org/10.1007/s10637-023-01344-9

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Concepts: Chimeric antigen receptor, Proinflammatory cytokine, Gene silencing, Cytokine, Immunotherapy, Gene knockdown, Small hairpin RNA, Immunology, Cancer research, Secretion, Cytokine release syndrome, Biology, Medicine, Inflammation, Cell culture, Immune system, Gene, Endocrinology, Genetics, Biochemistry

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Cited by: 6

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