Role of Cord Blood Albumin and Bilirubin for Prediction of Significant Neonatal Jaundice Article Swipe

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Nidhi Gupta , Shachi Jain Taran , Surabhi Gupta , Kewal kishore Arora ·

YOU? · · 2021 · Open Access · · DOI: https://doi.org/10.3126/jnps.v41i2.30383

Introduction: Nearly 60-80% of the term and preterm neonates are affected due to rise in bilirubin levels during early postnatal days, and causes readmission of the neonate sometimes with severe jaundice, which can be reduced if neonatal hyperbilirubinemia can be predicted early. The study was conducted to evaluate the predictive values of cord blood albumin and bilirubin for neonatal hyperbilirubinemia and to evaluate the better predictor between them. Method: In this hospital based observational study, 152 healthy term newborns with birth weight more than 2.5 kg were included. Assessment of cord blood haemoglobin, blood group, albumin and bilirubin levels was done. Follow-up for first consecutive five days after birth was done and assessed daily to look for evidence of jaundice, sepsis or any other illness. Serum bilirubin was evaluated at 72-96 hours of life in all neonates and was done early, if clinically indicated. Receiver’s Operating Characteristics curves were used for calculating the cut-off values of cord blood albumin and bilirubin in relation to hyperbilirubinemia. Result: The cut-off values obtained for albumin and bilirubin of cord blood was < 2.56 mg/dL and >2.33 mg/dL respectively at optimum sensitivity and specificity. Cord blood bilirubin was found to be highly sensitive for early recognition of significant neonatal hyperbilirubinemia as compared to cord blood albumin and can be used for screening purpose. Conclusion: Cord blood albumin and bilirubin can be used for negating the development of NNHB, but for screening purpose, cord blood bilirubin is more predictive of neonatal hyperbilirubinemia.

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Medicine Cord blood Jaundice Bilirubin Albumin Cord Sepsis Gastroenterology Serum albumin Neonatal sepsis Internal medicine Surgery

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Type: article
Language: en
Landing Page: https://doi.org/10.3126/jnps.v41i2.30383
PDF: https://www.nepjol.info/index.php/JNPS/article/download/30383/30952
OA Status: diamond
Cited By: 6
References: 16
Related Works: 10
OpenAlex ID: https://openalex.org/W3210534309

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OpenAlex ID: https://openalex.org/W3210534309

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DOI: https://doi.org/10.3126/jnps.v41i2.30383

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Title: Role of Cord Blood Albumin and Bilirubin for Prediction of Significant Neonatal Jaundice

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Type: article

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Language: en

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Publication year: 2021

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Publication date: 2021-11-03

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Authors: Nidhi Gupta, Shachi Jain Taran, Surabhi Gupta, Kewal kishore Arora

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Landing page: https://doi.org/10.3126/jnps.v41i2.30383

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PDF URL: https://www.nepjol.info/index.php/JNPS/article/download/30383/30952

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OA URL: https://www.nepjol.info/index.php/JNPS/article/download/30383/30952

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Concepts: Medicine, Cord blood, Jaundice, Bilirubin, Albumin, Cord, Sepsis, Gastroenterology, Serum albumin, Neonatal sepsis, Internal medicine, Surgery

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Cited by: 6

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Citations by year (recent): 2024: 1, 2023: 3, 2022: 2

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abstract_inverted_index.screening	217, 236
abstract_inverted_index.sensitive	198
abstract_inverted_index.sometimes	27
abstract_inverted_index.Assessment	88
abstract_inverted_index.clinically	142
abstract_inverted_index.indicated.	143
abstract_inverted_index.predictive	49, 243
abstract_inverted_index.Conclusion:	219
abstract_inverted_index.calculating	151
abstract_inverted_index.consecutive	104
abstract_inverted_index.development	231
abstract_inverted_index.readmission	23
abstract_inverted_index.recognition	201
abstract_inverted_index.sensitivity	187
abstract_inverted_index.significant	203
abstract_inverted_index.Receiver’s	144
abstract_inverted_index.haemoglobin,	92
abstract_inverted_index.respectively	184
abstract_inverted_index.specificity.	189
abstract_inverted_index.Introduction:	0
abstract_inverted_index.observational	73
abstract_inverted_index.Characteristics	146
abstract_inverted_index.hyperbilirubinemia	37, 59, 205
abstract_inverted_index.hyperbilirubinemia.	164, 246
cited_by_percentile_year.max	97
cited_by_percentile_year.min	90
countries_distinct_count	1
institutions_distinct_count	4
sustainable_development_goals[0].id	https://metadata.un.org/sdg/3
sustainable_development_goals[0].score	0.8100000023841858
sustainable_development_goals[0].display_name	Good health and well-being
citation_normalized_percentile.value	0.87335988
citation_normalized_percentile.is_in_top_1_percent	False
citation_normalized_percentile.is_in_top_10_percent	True