Saliva Free Light Chains in Patients with Neuro-Sjögren Article Swipe
Franz Felix Konen
,
Tabea Seeliger
,
Philipp Schwenkenbecher
,
Stefan Gingele
,
Konstantin Fritz Jendretzky
,
Kurt‐Wolfram Sühs
,
Diana Ernst
,
Torsten Witte
,
Thomas Skripuletz
·
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/biomedicines10102470
YOU?
·
· 2022
· Open Access
·
· DOI: https://doi.org/10.3390/biomedicines10102470
Background: Sjögren’s syndrome (SS) is an autoimmune disease characterized by sicca symptoms and various extra-glandular manifestations. The diagnosis of SS requires sicca symptoms, anti-SSA(Ro)-antibody positivity, and/or pathological focus scores on a minor salivary gland biopsy. Previous studies have investigated different biomarkers in order to avoid invasive diagnostic procedures. It was found that kappa and lambda free light chains (KFLC and LFLC) in saliva are specific for SS. Methods: FLC concentrations in saliva and serum were determined in 130 patients—50 with SS and neurological involvement (Neuro-Sjögren) and 80 neurological controls. The EULAR SS disease activity index and patient reported index (ESSPRI) were determined in patients with SS. Results: Patients with SS revealed increased pain and decreased saliva production according to the ESSPRI and Saxon test, respectively, with increasing FLC concentrations in the saliva. No significant differences in serum and salivary protein concentrations were observed between patients with SS and controls. Conclusion: KFLC and LFLC concentrations in saliva are not suitable to distinguish patients with Neuro-Sjögren and neurological control subjects, thus a diagnostic biopsy is still required. The association of salivary KFLC and LFLC concentrations with saliva production and ESSPRI pain score suggests a complex relationship between dryness and pain in patients with SS.
Related Topics
Concepts
Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.3390/biomedicines10102470
- https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705
- OA Status
- gold
- Cited By
- 4
- References
- 38
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4303614425
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
-
https://openalex.org/W4303614425Canonical identifier for this work in OpenAlex
- DOI
-
https://doi.org/10.3390/biomedicines10102470Digital Object Identifier
- Title
-
Saliva Free Light Chains in Patients with Neuro-SjögrenWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2022Year of publication
- Publication date
-
2022-10-03Full publication date if available
- Authors
-
Franz Felix Konen, Tabea Seeliger, Philipp Schwenkenbecher, Stefan Gingele, Konstantin Fritz Jendretzky, Kurt‐Wolfram Sühs, Diana Ernst, Torsten Witte, Thomas SkripuletzList of authors in order
- Landing page
-
https://doi.org/10.3390/biomedicines10102470Publisher landing page
- PDF URL
-
https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
goldOpen access status per OpenAlex
- OA URL
-
https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705Direct OA link when available
- Concepts
-
Saliva, Medicine, Internal medicineTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
4Total citation count in OpenAlex
- Citations by year (recent)
-
2025: 2, 2024: 1, 2023: 1Per-year citation counts (last 5 years)
- References (count)
-
38Number of works referenced by this work
- Related works (count)
-
10Other works algorithmically related by OpenAlex
Full payload
| id | https://openalex.org/W4303614425 |
|---|---|
| doi | https://doi.org/10.3390/biomedicines10102470 |
| ids.doi | https://doi.org/10.3390/biomedicines10102470 |
| ids.pmid | https://pubmed.ncbi.nlm.nih.gov/36289732 |
| ids.openalex | https://openalex.org/W4303614425 |
| fwci | 0.71798548 |
| type | article |
| title | Saliva Free Light Chains in Patients with Neuro-Sjögren |
| biblio.issue | 10 |
| biblio.volume | 10 |
| biblio.last_page | 2470 |
| biblio.first_page | 2470 |
| topics[0].id | https://openalex.org/T11521 |
| topics[0].field.id | https://openalex.org/fields/27 |
| topics[0].field.display_name | Medicine |
| topics[0].score | 1.0 |
| topics[0].domain.id | https://openalex.org/domains/4 |
| topics[0].domain.display_name | Health Sciences |
| topics[0].subfield.id | https://openalex.org/subfields/2737 |
| topics[0].subfield.display_name | Physiology |
| topics[0].display_name | Salivary Gland Disorders and Functions |
| topics[1].id | https://openalex.org/T10971 |
| topics[1].field.id | https://openalex.org/fields/28 |
| topics[1].field.display_name | Neuroscience |
| topics[1].score | 0.9952999949455261 |
| topics[1].domain.id | https://openalex.org/domains/1 |
| topics[1].domain.display_name | Life Sciences |
| topics[1].subfield.id | https://openalex.org/subfields/2809 |
| topics[1].subfield.display_name | Sensory Systems |
| topics[1].display_name | Olfactory and Sensory Function Studies |
| topics[2].id | https://openalex.org/T12580 |
| topics[2].field.id | https://openalex.org/fields/28 |
| topics[2].field.display_name | Neuroscience |
| topics[2].score | 0.9627000093460083 |
| topics[2].domain.id | https://openalex.org/domains/1 |
| topics[2].domain.display_name | Life Sciences |
| topics[2].subfield.id | https://openalex.org/subfields/2808 |
| topics[2].subfield.display_name | Neurology |
| topics[2].display_name | Vagus Nerve Stimulation Research |
| is_xpac | False |
| apc_list.value | 2200 |
| apc_list.currency | CHF |
| apc_list.value_usd | 2382 |
| apc_paid.value | 2200 |
| apc_paid.currency | CHF |
| apc_paid.value_usd | 2382 |
| concepts[0].id | https://openalex.org/C504460877 |
| concepts[0].level | 2 |
| concepts[0].score | 0.7411781549453735 |
| concepts[0].wikidata | https://www.wikidata.org/wiki/Q155925 |
| concepts[0].display_name | Saliva |
| concepts[1].id | https://openalex.org/C71924100 |
| concepts[1].level | 0 |
| concepts[1].score | 0.42565885186195374 |
| concepts[1].wikidata | https://www.wikidata.org/wiki/Q11190 |
| concepts[1].display_name | Medicine |
| concepts[2].id | https://openalex.org/C126322002 |
| concepts[2].level | 1 |
| concepts[2].score | 0.22081419825553894 |
| concepts[2].wikidata | https://www.wikidata.org/wiki/Q11180 |
| concepts[2].display_name | Internal medicine |
| keywords[0].id | https://openalex.org/keywords/saliva |
| keywords[0].score | 0.7411781549453735 |
| keywords[0].display_name | Saliva |
| keywords[1].id | https://openalex.org/keywords/medicine |
| keywords[1].score | 0.42565885186195374 |
| keywords[1].display_name | Medicine |
| keywords[2].id | https://openalex.org/keywords/internal-medicine |
| keywords[2].score | 0.22081419825553894 |
| keywords[2].display_name | Internal medicine |
| language | en |
| locations[0].id | doi:10.3390/biomedicines10102470 |
| locations[0].is_oa | True |
| locations[0].source.id | https://openalex.org/S2737005842 |
| locations[0].source.issn | 2227-9059 |
| locations[0].source.type | journal |
| locations[0].source.is_oa | True |
| locations[0].source.issn_l | 2227-9059 |
| locations[0].source.is_core | True |
| locations[0].source.is_in_doaj | True |
| locations[0].source.display_name | Biomedicines |
| locations[0].source.host_organization | https://openalex.org/P4310310987 |
| locations[0].source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| locations[0].source.host_organization_lineage | https://openalex.org/P4310310987 |
| locations[0].license | cc-by |
| locations[0].pdf_url | https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705 |
| locations[0].version | publishedVersion |
| locations[0].raw_type | journal-article |
| locations[0].license_id | https://openalex.org/licenses/cc-by |
| locations[0].is_accepted | True |
| locations[0].is_published | True |
| locations[0].raw_source_name | Biomedicines |
| locations[0].landing_page_url | https://doi.org/10.3390/biomedicines10102470 |
| locations[1].id | pmid:36289732 |
| locations[1].is_oa | False |
| locations[1].source.id | https://openalex.org/S4306525036 |
| locations[1].source.issn | |
| locations[1].source.type | repository |
| locations[1].source.is_oa | False |
| locations[1].source.issn_l | |
| locations[1].source.is_core | False |
| locations[1].source.is_in_doaj | False |
| locations[1].source.display_name | PubMed |
| locations[1].source.host_organization | https://openalex.org/I1299303238 |
| locations[1].source.host_organization_name | National Institutes of Health |
| locations[1].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[1].license | |
| locations[1].pdf_url | |
| locations[1].version | publishedVersion |
| locations[1].raw_type | |
| locations[1].license_id | |
| locations[1].is_accepted | True |
| locations[1].is_published | True |
| locations[1].raw_source_name | Biomedicines |
| locations[1].landing_page_url | https://pubmed.ncbi.nlm.nih.gov/36289732 |
| locations[2].id | pmh:oai:pubmedcentral.nih.gov:9599066 |
| locations[2].is_oa | True |
| locations[2].source.id | https://openalex.org/S2764455111 |
| locations[2].source.issn | |
| locations[2].source.type | repository |
| locations[2].source.is_oa | False |
| locations[2].source.issn_l | |
| locations[2].source.is_core | False |
| locations[2].source.is_in_doaj | False |
| locations[2].source.display_name | PubMed Central |
| locations[2].source.host_organization | https://openalex.org/I1299303238 |
| locations[2].source.host_organization_name | National Institutes of Health |
| locations[2].source.host_organization_lineage | https://openalex.org/I1299303238 |
| locations[2].license | other-oa |
| locations[2].pdf_url | |
| locations[2].version | submittedVersion |
| locations[2].raw_type | Text |
| locations[2].license_id | https://openalex.org/licenses/other-oa |
| locations[2].is_accepted | False |
| locations[2].is_published | False |
| locations[2].raw_source_name | Biomedicines |
| locations[2].landing_page_url | https://www.ncbi.nlm.nih.gov/pmc/articles/9599066 |
| locations[3].id | pmh:oai:doaj.org/article:7065748e27a44d36897fd055e449c8c7 |
| locations[3].is_oa | True |
| locations[3].source.id | https://openalex.org/S4306401280 |
| locations[3].source.issn | |
| locations[3].source.type | repository |
| locations[3].source.is_oa | False |
| locations[3].source.issn_l | |
| locations[3].source.is_core | False |
| locations[3].source.is_in_doaj | False |
| locations[3].source.display_name | DOAJ (DOAJ: Directory of Open Access Journals) |
| locations[3].source.host_organization | |
| locations[3].source.host_organization_name | |
| locations[3].source.host_organization_lineage | |
| locations[3].license | cc-by-sa |
| locations[3].pdf_url | |
| locations[3].version | submittedVersion |
| locations[3].raw_type | article |
| locations[3].license_id | https://openalex.org/licenses/cc-by-sa |
| locations[3].is_accepted | False |
| locations[3].is_published | False |
| locations[3].raw_source_name | Biomedicines, Vol 10, Iss 10, p 2470 (2022) |
| locations[3].landing_page_url | https://doaj.org/article/7065748e27a44d36897fd055e449c8c7 |
| locations[4].id | pmh:oai:mdpi.com:/2227-9059/10/10/2470/ |
| locations[4].is_oa | True |
| locations[4].source.id | https://openalex.org/S4306400947 |
| locations[4].source.issn | |
| locations[4].source.type | repository |
| locations[4].source.is_oa | True |
| locations[4].source.issn_l | |
| locations[4].source.is_core | False |
| locations[4].source.is_in_doaj | False |
| locations[4].source.display_name | MDPI (MDPI AG) |
| locations[4].source.host_organization | https://openalex.org/I4210097602 |
| locations[4].source.host_organization_name | Multidisciplinary Digital Publishing Institute (Switzerland) |
| locations[4].source.host_organization_lineage | https://openalex.org/I4210097602 |
| locations[4].license | cc-by |
| locations[4].pdf_url | |
| locations[4].version | submittedVersion |
| locations[4].raw_type | Text |
| locations[4].license_id | https://openalex.org/licenses/cc-by |
| locations[4].is_accepted | False |
| locations[4].is_published | False |
| locations[4].raw_source_name | Biomedicines; Volume 10; Issue 10; Pages: 2470 |
| locations[4].landing_page_url | https://dx.doi.org/10.3390/biomedicines10102470 |
| indexed_in | crossref, doaj, pubmed |
| authorships[0].author.id | https://openalex.org/A5068885506 |
| authorships[0].author.orcid | https://orcid.org/0000-0002-8609-5674 |
| authorships[0].author.display_name | Franz Felix Konen |
| authorships[0].countries | DE |
| authorships[0].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[0].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[0].institutions[0].id | https://openalex.org/I34809795 |
| authorships[0].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[0].institutions[0].type | education |
| authorships[0].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[0].institutions[0].country_code | DE |
| authorships[0].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[0].author_position | first |
| authorships[0].raw_author_name | Franz Felix Konen |
| authorships[0].is_corresponding | False |
| authorships[0].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[1].author.id | https://openalex.org/A5001679610 |
| authorships[1].author.orcid | https://orcid.org/0000-0002-6018-6826 |
| authorships[1].author.display_name | Tabea Seeliger |
| authorships[1].countries | DE |
| authorships[1].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[1].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[1].institutions[0].id | https://openalex.org/I34809795 |
| authorships[1].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[1].institutions[0].type | education |
| authorships[1].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[1].institutions[0].country_code | DE |
| authorships[1].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[1].author_position | middle |
| authorships[1].raw_author_name | Tabea Seeliger |
| authorships[1].is_corresponding | False |
| authorships[1].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[2].author.id | https://openalex.org/A5039847442 |
| authorships[2].author.orcid | https://orcid.org/0000-0002-1260-1650 |
| authorships[2].author.display_name | Philipp Schwenkenbecher |
| authorships[2].countries | DE |
| authorships[2].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[2].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[2].institutions[0].id | https://openalex.org/I34809795 |
| authorships[2].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[2].institutions[0].type | education |
| authorships[2].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[2].institutions[0].country_code | DE |
| authorships[2].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[2].author_position | middle |
| authorships[2].raw_author_name | Philipp Schwenkenbecher |
| authorships[2].is_corresponding | False |
| authorships[2].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[3].author.id | https://openalex.org/A5003028142 |
| authorships[3].author.orcid | https://orcid.org/0000-0002-6055-5695 |
| authorships[3].author.display_name | Stefan Gingele |
| authorships[3].countries | DE |
| authorships[3].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[3].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[3].institutions[0].id | https://openalex.org/I34809795 |
| authorships[3].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[3].institutions[0].type | education |
| authorships[3].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[3].institutions[0].country_code | DE |
| authorships[3].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[3].author_position | middle |
| authorships[3].raw_author_name | Stefan Gingele |
| authorships[3].is_corresponding | False |
| authorships[3].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[4].author.id | https://openalex.org/A5077490436 |
| authorships[4].author.orcid | |
| authorships[4].author.display_name | Konstantin Fritz Jendretzky |
| authorships[4].countries | DE |
| authorships[4].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[4].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[4].institutions[0].id | https://openalex.org/I34809795 |
| authorships[4].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[4].institutions[0].type | education |
| authorships[4].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[4].institutions[0].country_code | DE |
| authorships[4].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[4].author_position | middle |
| authorships[4].raw_author_name | Konstantin Fritz Jendretzky |
| authorships[4].is_corresponding | False |
| authorships[4].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[5].author.id | https://openalex.org/A5048460745 |
| authorships[5].author.orcid | https://orcid.org/0000-0002-8077-481X |
| authorships[5].author.display_name | Kurt‐Wolfram Sühs |
| authorships[5].countries | DE |
| authorships[5].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[5].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[5].institutions[0].id | https://openalex.org/I34809795 |
| authorships[5].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[5].institutions[0].type | education |
| authorships[5].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[5].institutions[0].country_code | DE |
| authorships[5].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[5].author_position | middle |
| authorships[5].raw_author_name | Kurt-Wolfram Sühs |
| authorships[5].is_corresponding | False |
| authorships[5].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[6].author.id | https://openalex.org/A5111535230 |
| authorships[6].author.orcid | https://orcid.org/0000-0003-0736-6243 |
| authorships[6].author.display_name | Diana Ernst |
| authorships[6].countries | DE |
| authorships[6].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[6].affiliations[0].raw_affiliation_string | Department of Immunology & Rheumatology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[6].institutions[0].id | https://openalex.org/I34809795 |
| authorships[6].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[6].institutions[0].type | education |
| authorships[6].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[6].institutions[0].country_code | DE |
| authorships[6].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[6].author_position | middle |
| authorships[6].raw_author_name | Diana Ernst |
| authorships[6].is_corresponding | False |
| authorships[6].raw_affiliation_strings | Department of Immunology & Rheumatology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[7].author.id | https://openalex.org/A5031205195 |
| authorships[7].author.orcid | https://orcid.org/0000-0003-4531-0267 |
| authorships[7].author.display_name | Torsten Witte |
| authorships[7].countries | DE |
| authorships[7].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[7].affiliations[0].raw_affiliation_string | Department of Immunology & Rheumatology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[7].institutions[0].id | https://openalex.org/I34809795 |
| authorships[7].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[7].institutions[0].type | education |
| authorships[7].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[7].institutions[0].country_code | DE |
| authorships[7].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[7].author_position | middle |
| authorships[7].raw_author_name | Torsten Witte |
| authorships[7].is_corresponding | False |
| authorships[7].raw_affiliation_strings | Department of Immunology & Rheumatology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[8].author.id | https://openalex.org/A5001155888 |
| authorships[8].author.orcid | https://orcid.org/0000-0001-8550-335X |
| authorships[8].author.display_name | Thomas Skripuletz |
| authorships[8].countries | DE |
| authorships[8].affiliations[0].institution_ids | https://openalex.org/I34809795 |
| authorships[8].affiliations[0].raw_affiliation_string | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| authorships[8].institutions[0].id | https://openalex.org/I34809795 |
| authorships[8].institutions[0].ror | https://ror.org/00f2yqf98 |
| authorships[8].institutions[0].type | education |
| authorships[8].institutions[0].lineage | https://openalex.org/I34809795 |
| authorships[8].institutions[0].country_code | DE |
| authorships[8].institutions[0].display_name | Medizinische Hochschule Hannover |
| authorships[8].author_position | last |
| authorships[8].raw_author_name | Thomas Skripuletz |
| authorships[8].is_corresponding | True |
| authorships[8].raw_affiliation_strings | Department of Neurology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany |
| has_content.pdf | True |
| has_content.grobid_xml | True |
| is_paratext | False |
| open_access.is_oa | True |
| open_access.oa_url | https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705 |
| open_access.oa_status | gold |
| open_access.any_repository_has_fulltext | False |
| created_date | 2025-10-10T00:00:00 |
| display_name | Saliva Free Light Chains in Patients with Neuro-Sjögren |
| has_fulltext | True |
| is_retracted | False |
| updated_date | 2025-11-06T03:46:38.306776 |
| primary_topic.id | https://openalex.org/T11521 |
| primary_topic.field.id | https://openalex.org/fields/27 |
| primary_topic.field.display_name | Medicine |
| primary_topic.score | 1.0 |
| primary_topic.domain.id | https://openalex.org/domains/4 |
| primary_topic.domain.display_name | Health Sciences |
| primary_topic.subfield.id | https://openalex.org/subfields/2737 |
| primary_topic.subfield.display_name | Physiology |
| primary_topic.display_name | Salivary Gland Disorders and Functions |
| related_works | https://openalex.org/W2748952813, https://openalex.org/W3031052312, https://openalex.org/W4389568370, https://openalex.org/W3032375762, https://openalex.org/W1995515455, https://openalex.org/W2080531066, https://openalex.org/W3108674512, https://openalex.org/W1506200166, https://openalex.org/W1489783725, https://openalex.org/W2148612803 |
| cited_by_count | 4 |
| counts_by_year[0].year | 2025 |
| counts_by_year[0].cited_by_count | 2 |
| counts_by_year[1].year | 2024 |
| counts_by_year[1].cited_by_count | 1 |
| counts_by_year[2].year | 2023 |
| counts_by_year[2].cited_by_count | 1 |
| locations_count | 5 |
| best_oa_location.id | doi:10.3390/biomedicines10102470 |
| best_oa_location.is_oa | True |
| best_oa_location.source.id | https://openalex.org/S2737005842 |
| best_oa_location.source.issn | 2227-9059 |
| best_oa_location.source.type | journal |
| best_oa_location.source.is_oa | True |
| best_oa_location.source.issn_l | 2227-9059 |
| best_oa_location.source.is_core | True |
| best_oa_location.source.is_in_doaj | True |
| best_oa_location.source.display_name | Biomedicines |
| best_oa_location.source.host_organization | https://openalex.org/P4310310987 |
| best_oa_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| best_oa_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| best_oa_location.license | cc-by |
| best_oa_location.pdf_url | https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705 |
| best_oa_location.version | publishedVersion |
| best_oa_location.raw_type | journal-article |
| best_oa_location.license_id | https://openalex.org/licenses/cc-by |
| best_oa_location.is_accepted | True |
| best_oa_location.is_published | True |
| best_oa_location.raw_source_name | Biomedicines |
| best_oa_location.landing_page_url | https://doi.org/10.3390/biomedicines10102470 |
| primary_location.id | doi:10.3390/biomedicines10102470 |
| primary_location.is_oa | True |
| primary_location.source.id | https://openalex.org/S2737005842 |
| primary_location.source.issn | 2227-9059 |
| primary_location.source.type | journal |
| primary_location.source.is_oa | True |
| primary_location.source.issn_l | 2227-9059 |
| primary_location.source.is_core | True |
| primary_location.source.is_in_doaj | True |
| primary_location.source.display_name | Biomedicines |
| primary_location.source.host_organization | https://openalex.org/P4310310987 |
| primary_location.source.host_organization_name | Multidisciplinary Digital Publishing Institute |
| primary_location.source.host_organization_lineage | https://openalex.org/P4310310987 |
| primary_location.license | cc-by |
| primary_location.pdf_url | https://www.mdpi.com/2227-9059/10/10/2470/pdf?version=1664785705 |
| primary_location.version | publishedVersion |
| primary_location.raw_type | journal-article |
| primary_location.license_id | https://openalex.org/licenses/cc-by |
| primary_location.is_accepted | True |
| primary_location.is_published | True |
| primary_location.raw_source_name | Biomedicines |
| primary_location.landing_page_url | https://doi.org/10.3390/biomedicines10102470 |
| publication_date | 2022-10-03 |
| publication_year | 2022 |
| referenced_works | https://openalex.org/W2030711090, https://openalex.org/W4200605822, https://openalex.org/W3180181087, https://openalex.org/W3049675335, https://openalex.org/W3043616480, https://openalex.org/W3025492510, https://openalex.org/W2540091234, https://openalex.org/W2147546090, https://openalex.org/W2044570210, https://openalex.org/W2786928529, https://openalex.org/W2022755336, https://openalex.org/W2806104832, https://openalex.org/W2795147888, https://openalex.org/W2810890866, https://openalex.org/W2562509644, https://openalex.org/W3213612681, https://openalex.org/W2561533867, https://openalex.org/W3214224030, https://openalex.org/W2989402348, https://openalex.org/W2902850345, https://openalex.org/W1823789485, https://openalex.org/W1967834717, https://openalex.org/W2105452082, https://openalex.org/W2960265880, https://openalex.org/W3131433931, https://openalex.org/W1966736991, https://openalex.org/W2155965977, https://openalex.org/W4289339395, https://openalex.org/W3038206929, https://openalex.org/W4224307779, https://openalex.org/W3214947182, https://openalex.org/W1525188084, https://openalex.org/W4225837042, https://openalex.org/W3156012201, https://openalex.org/W3014332360, https://openalex.org/W4225854680, https://openalex.org/W2607031541, https://openalex.org/W2913829063 |
| referenced_works_count | 38 |
| abstract_inverted_index.a | 30, 169, 191 |
| abstract_inverted_index.80 | 86 |
| abstract_inverted_index.It | 48 |
| abstract_inverted_index.No | 132 |
| abstract_inverted_index.SS | 19, 80, 91, 109, 146 |
| abstract_inverted_index.an | 5 |
| abstract_inverted_index.by | 9 |
| abstract_inverted_index.in | 41, 61, 70, 76, 102, 129, 135, 154, 198 |
| abstract_inverted_index.is | 4, 172 |
| abstract_inverted_index.of | 18, 177 |
| abstract_inverted_index.on | 29 |
| abstract_inverted_index.to | 43, 118, 159 |
| abstract_inverted_index.130 | 77 |
| abstract_inverted_index.FLC | 68, 127 |
| abstract_inverted_index.SS. | 66, 105, 201 |
| abstract_inverted_index.The | 16, 89, 175 |
| abstract_inverted_index.and | 12, 53, 59, 72, 81, 85, 95, 113, 121, 137, 147, 151, 164, 180, 186, 196 |
| abstract_inverted_index.are | 63, 156 |
| abstract_inverted_index.for | 65 |
| abstract_inverted_index.not | 157 |
| abstract_inverted_index.the | 119, 130 |
| abstract_inverted_index.was | 49 |
| abstract_inverted_index.(SS) | 3 |
| abstract_inverted_index.KFLC | 150, 179 |
| abstract_inverted_index.LFLC | 152, 181 |
| abstract_inverted_index.free | 55 |
| abstract_inverted_index.have | 37 |
| abstract_inverted_index.pain | 112, 188, 197 |
| abstract_inverted_index.that | 51 |
| abstract_inverted_index.thus | 168 |
| abstract_inverted_index.were | 74, 100, 141 |
| abstract_inverted_index.with | 79, 104, 108, 125, 145, 162, 183, 200 |
| abstract_inverted_index.(KFLC | 58 |
| abstract_inverted_index.EULAR | 90 |
| abstract_inverted_index.LFLC) | 60 |
| abstract_inverted_index.Saxon | 122 |
| abstract_inverted_index.avoid | 44 |
| abstract_inverted_index.focus | 27 |
| abstract_inverted_index.found | 50 |
| abstract_inverted_index.gland | 33 |
| abstract_inverted_index.index | 94, 98 |
| abstract_inverted_index.kappa | 52 |
| abstract_inverted_index.light | 56 |
| abstract_inverted_index.minor | 31 |
| abstract_inverted_index.order | 42 |
| abstract_inverted_index.score | 189 |
| abstract_inverted_index.serum | 73, 136 |
| abstract_inverted_index.sicca | 10, 21 |
| abstract_inverted_index.still | 173 |
| abstract_inverted_index.test, | 123 |
| abstract_inverted_index.ESSPRI | 120, 187 |
| abstract_inverted_index.and/or | 25 |
| abstract_inverted_index.biopsy | 171 |
| abstract_inverted_index.chains | 57 |
| abstract_inverted_index.lambda | 54 |
| abstract_inverted_index.saliva | 62, 71, 115, 155, 184 |
| abstract_inverted_index.scores | 28 |
| abstract_inverted_index.between | 143, 194 |
| abstract_inverted_index.biopsy. | 34 |
| abstract_inverted_index.complex | 192 |
| abstract_inverted_index.control | 166 |
| abstract_inverted_index.disease | 7, 92 |
| abstract_inverted_index.dryness | 195 |
| abstract_inverted_index.patient | 96 |
| abstract_inverted_index.protein | 139 |
| abstract_inverted_index.saliva. | 131 |
| abstract_inverted_index.studies | 36 |
| abstract_inverted_index.various | 13 |
| abstract_inverted_index.(ESSPRI) | 99 |
| abstract_inverted_index.Methods: | 67 |
| abstract_inverted_index.Patients | 107 |
| abstract_inverted_index.Previous | 35 |
| abstract_inverted_index.Results: | 106 |
| abstract_inverted_index.activity | 93 |
| abstract_inverted_index.invasive | 45 |
| abstract_inverted_index.observed | 142 |
| abstract_inverted_index.patients | 103, 144, 161, 199 |
| abstract_inverted_index.reported | 97 |
| abstract_inverted_index.requires | 20 |
| abstract_inverted_index.revealed | 110 |
| abstract_inverted_index.salivary | 32, 138, 178 |
| abstract_inverted_index.specific | 64 |
| abstract_inverted_index.suggests | 190 |
| abstract_inverted_index.suitable | 158 |
| abstract_inverted_index.symptoms | 11 |
| abstract_inverted_index.syndrome | 2 |
| abstract_inverted_index.according | 117 |
| abstract_inverted_index.controls. | 88, 148 |
| abstract_inverted_index.decreased | 114 |
| abstract_inverted_index.diagnosis | 17 |
| abstract_inverted_index.different | 39 |
| abstract_inverted_index.increased | 111 |
| abstract_inverted_index.required. | 174 |
| abstract_inverted_index.subjects, | 167 |
| abstract_inverted_index.symptoms, | 22 |
| abstract_inverted_index.autoimmune | 6 |
| abstract_inverted_index.biomarkers | 40 |
| abstract_inverted_index.determined | 75, 101 |
| abstract_inverted_index.diagnostic | 46, 170 |
| abstract_inverted_index.increasing | 126 |
| abstract_inverted_index.production | 116, 185 |
| abstract_inverted_index.Background: | 0 |
| abstract_inverted_index.Conclusion: | 149 |
| abstract_inverted_index.association | 176 |
| abstract_inverted_index.differences | 134 |
| abstract_inverted_index.distinguish | 160 |
| abstract_inverted_index.involvement | 83 |
| abstract_inverted_index.positivity, | 24 |
| abstract_inverted_index.procedures. | 47 |
| abstract_inverted_index.significant | 133 |
| abstract_inverted_index.Sjögren’s | 1 |
| abstract_inverted_index.investigated | 38 |
| abstract_inverted_index.neurological | 82, 87, 165 |
| abstract_inverted_index.pathological | 26 |
| abstract_inverted_index.relationship | 193 |
| abstract_inverted_index.characterized | 8 |
| abstract_inverted_index.patients—50 | 78 |
| abstract_inverted_index.respectively, | 124 |
| abstract_inverted_index.Neuro-Sjögren | 163 |
| abstract_inverted_index.concentrations | 69, 128, 140, 153, 182 |
| abstract_inverted_index.extra-glandular | 14 |
| abstract_inverted_index.manifestations. | 15 |
| abstract_inverted_index.(Neuro-Sjögren) | 84 |
| abstract_inverted_index.anti-SSA(Ro)-antibody | 23 |
| cited_by_percentile_year.max | 97 |
| cited_by_percentile_year.min | 89 |
| corresponding_author_ids | https://openalex.org/A5001155888 |
| countries_distinct_count | 1 |
| institutions_distinct_count | 9 |
| corresponding_institution_ids | https://openalex.org/I34809795 |
| sustainable_development_goals[0].id | https://metadata.un.org/sdg/3 |
| sustainable_development_goals[0].score | 0.7400000095367432 |
| sustainable_development_goals[0].display_name | Good health and well-being |
| citation_normalized_percentile.value | 0.64251296 |
| citation_normalized_percentile.is_in_top_1_percent | False |
| citation_normalized_percentile.is_in_top_10_percent | False |