Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria Article Swipe
Kazuya Saito
,
Taisuke Nakade
,
Nobuyuki Kagiyama
,
Daichi Maeda
,
Yudai Fujimoto
,
Tsutomu Sunayama
,
Taishi Dotare
,
Kentaro Jujo
,
Kentaro Kamiya
,
Hiroshi Saito
,
Yuki Ogasahara
,
Emi Maekawa
,
Masaaki Konishi
,
Takeshi Kitai
,
K. Iwata
,
Hiroshi Wada
,
Takatoshi Kasai
,
Hirofumi Nagamatsu
,
Shin‐ichi Momomura
,
Daichi Maeda
·
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1111/ggi.70040
YOU?
·
· 2025
· Open Access
·
· DOI: https://doi.org/10.1111/ggi.70040
Aim Sarcopenia is a prevalent comorbidity among older patients with heart failure. This study aimed to evaluate the differences between sarcopenia diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2014 and 2019 criteria in older patients with heart failure. Methods This study is a post hoc sub‐analysis of data from the FRAGILE‐HF study, a prospective, multicenter, observational study. The study included 879 patients aged >65 years who were hospitalized for heart failure decompensation and could walk at discharge. Sarcopenia was diagnosed using criteria from the AWGS 2014 (2014 model) and 2019 (2019 model). The primary outcome was 2‐year mortality. Results Sarcopenia was identified in 186 (21.1%) patients using the 2014 model and 211 (24.0%) patients using the 2019 model. Over the 2‐year follow‐up period, 158 (18.0%) deaths occurred. Adjusted Cox proportional hazard analysis showed that sarcopenia was significantly associated with 2‐year mortality in the 2014 model, whereas only severe sarcopenia was associated with mortality in the 2019 model. Both models showed significant net reclassification improvement when sarcopenia was added to the baseline model (2014 model: 0.358, 2019 model: 0.357). However, no significant difference in net reclassification improvement was observed upon direct comparison between the two models (−0.082, P = 0.376), suggesting comparable performance. Conclusions The 2014 model shows strong prognostic value for predicting 2‐year mortality in patients with heart failure. Although the 2019 model shows similar prognostic value, particularly for severe sarcopenia, it does not significantly outperform the 2014 model. Geriatr Gerontol Int 2025; 25: 764–771 .
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Metadata
- Type
- article
- Language
- en
- Landing Page
- https://doi.org/10.1111/ggi.70040
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ggi.70040
- OA Status
- bronze
- References
- 27
- Related Works
- 10
- OpenAlex ID
- https://openalex.org/W4410182533
All OpenAlex metadata
Raw OpenAlex JSON
- OpenAlex ID
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https://openalex.org/W4410182533Canonical identifier for this work in OpenAlex
- DOI
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https://doi.org/10.1111/ggi.70040Digital Object Identifier
- Title
-
Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteriaWork title
- Type
-
articleOpenAlex work type
- Language
-
enPrimary language
- Publication year
-
2025Year of publication
- Publication date
-
2025-05-06Full publication date if available
- Authors
-
Kazuya Saito, Taisuke Nakade, Nobuyuki Kagiyama, Daichi Maeda, Yudai Fujimoto, Tsutomu Sunayama, Taishi Dotare, Kentaro Jujo, Kentaro Kamiya, Hiroshi Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, K. Iwata, Hiroshi Wada, Takatoshi Kasai, Hirofumi Nagamatsu, Shin‐ichi Momomura, Daichi MaedaList of authors in order
- Landing page
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https://doi.org/10.1111/ggi.70040Publisher landing page
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-
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ggi.70040Direct link to full text PDF
- Open access
-
YesWhether a free full text is available
- OA status
-
bronzeOpen access status per OpenAlex
- OA URL
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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ggi.70040Direct OA link when available
- Concepts
-
Sarcopenia, Medicine, Proportional hazards model, Heart failure, Hazard ratio, Internal medicine, Comorbidity, Decompensation, Observational study, Prospective cohort study, Cardiology, Confidence intervalTop concepts (fields/topics) attached by OpenAlex
- Cited by
-
0Total citation count in OpenAlex
- References (count)
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27Number of works referenced by this work
- Related works (count)
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10Other works algorithmically related by OpenAlex
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| primary_location.raw_source_name | Geriatrics & Gerontology International |
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| publication_date | 2025-05-06 |
| publication_year | 2025 |
| referenced_works | https://openalex.org/W1900956557, https://openalex.org/W4385841420, https://openalex.org/W2889669803, https://openalex.org/W2580792129, https://openalex.org/W2897513125, https://openalex.org/W3040961354, https://openalex.org/W2608488150, https://openalex.org/W4390024336, https://openalex.org/W2132273917, https://openalex.org/W3005437800, https://openalex.org/W3034004005, https://openalex.org/W4383998654, https://openalex.org/W4393929711, https://openalex.org/W4396812803, https://openalex.org/W4388979158, https://openalex.org/W3215685111, https://openalex.org/W2113865982, https://openalex.org/W3125736010, https://openalex.org/W1508372417, https://openalex.org/W4394759745, https://openalex.org/W2001984572, https://openalex.org/W4405075239, https://openalex.org/W4323923461, https://openalex.org/W4309669918, https://openalex.org/W4392013501, https://openalex.org/W4224315270, https://openalex.org/W4399940523 |
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